LOCUS       NP_001359439             540 aa            linear   ROD 02-MAY-2024
DEFINITION  upstream-binding protein 1 isoform a [Mus musculus].
ACCESSION   NP_001359439 XP_006512114
VERSION     NP_001359439.1
DBSOURCE    REFSEQ: accession NM_001372510.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 540)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (residues 1 to 540)
  AUTHORS   Gurdziel,K., Vogt,K.R., Walton,K.D., Schneider,G.K. and
            Gumucio,D.L.
  TITLE     Transcriptome of the inner circular smooth muscle of the developing
            mouse intestine: Evidence for regulation of visceral smooth muscle
            genes by the hedgehog target gene, cJun
  JOURNAL   Dev Dyn 245 (5), 614-626 (2016)
   PUBMED   26930384
REFERENCE   3  (residues 1 to 540)
  AUTHORS   Lin,J.C., Lu,Y.H., Liu,Y.R. and Lin,Y.J.
  TITLE     RBM4a-regulated splicing cascade modulates the differentiation and
            metabolic activities of brown adipocytes
  JOURNAL   Sci Rep 6, 20665 (2016)
   PUBMED   26857472
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 540)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   5  (residues 1 to 540)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   6  (residues 1 to 540)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   7  (residues 1 to 540)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   8  (residues 1 to 540)
  AUTHORS   Ramamurthy,L., Barbour,V., Tuckfield,A., Clouston,D.R., Topham,D.,
            Cunningham,J.M. and Jane,S.M.
  TITLE     Targeted disruption of the CP2 gene, a member of the NTF family of
            transcription factors
  JOURNAL   J Biol Chem 276 (11), 7836-7842 (2001)
   PUBMED   10995745
REFERENCE   9  (residues 1 to 540)
  AUTHORS   Sueyoshi,T., Kobayashi,R., Nishio,K., Aida,K., Moore,R., Wada,T.,
            Handa,H. and Negishi,M.
  TITLE     A nuclear factor (NF2d9) that binds to the male-specific P450 (Cyp
            2d-9) gene in mouse liver
  JOURNAL   Mol Cell Biol 15 (8), 4158-4166 (1995)
   PUBMED   7623810
REFERENCE   10 (residues 1 to 540)
  AUTHORS   Sanno,Y., Holzer,M. and Schimke,R.T.
  TITLE     Studies of a mutation affecting pyrimidine degradation in inbred
            mice
  JOURNAL   J Biol Chem 245 (21), 5668-5676 (1970)
   PUBMED   5472365
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC107803.15 and CT025531.9.
            
            On Sep 3, 2019 this sequence version replaced XP_006512114.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY182062.1, SRR1660819.117072.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..540
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 64.14 cM"
     Protein         1..540
                     /product="upstream-binding protein 1 isoform a"
                     /note="nuclear factor 2d9"
                     /calculated_mol_wt=60081
     Region          1..40
                     /region_name="Transcriptional activation"
                     /note="propagated from UniProtKB/Swiss-Prot (Q811S7.1)"
     Site            22
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9NZI7; propagated from
                     UniProtKB/Swiss-Prot (Q811S7.1)"
     Region          50..254
                     /region_name="CP2"
                     /note="CP2 transcription factor; pfam04516"
                     /db_xref="CDD:461338"
     Region          235..265
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q811S7.1)"
     Region          274..309
                     /region_name="Erythroid-specific transcriptional
                     activation"
                     /note="propagated from UniProtKB/Swiss-Prot (Q811S7.1)"
     Region          285..372
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q811S7.1)"
     Region          369..435
                     /region_name="SAM_LBP1"
                     /note="SAM domain of LBP1 (UBP1) transcription factors;
                     cd09588"
                     /db_xref="CDD:188987"
     Site            390
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q811S7.1)"
     Site            393
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q811S7.1)"
     CDS             1..540
                     /gene="Ubp1"
                     /gene_synonym="Cp2b; LBP-1a; LBP-1b; NF2d9"
                     /coded_by="NM_001372510.1:343..1965"
                     /note="isoform a is encoded by transcript variant 5"
                     /db_xref="GeneID:22221"
                     /db_xref="MGI:MGI:104889"
ORIGIN      
        1 mawvlsmdev iesglvhdfd sslsgigqel gagaysmsdv lalpifkqed sslsledeak
       61 hppfqyvmca atspavklhd etltylnqgq syeirmldnr kmgdmpelsg klvksiirvv
      121 fhdrrlqyte hqqlegwkwn rpgdrlldld ipmsvgiidt rtnpsqlnav eflwdpakrt
      181 safiqvhcis teftprkhgg ekgvpfriqv dtfkqnenge ytdhlhsasc qikvfkpkga
      241 drkqkndrek mekrtaheke kyqpsydtti ltemrlepii edaveheqkk sskrtlpady
      301 gdslakrgsc spwpdtptay vnnspspapt ftssqpstcs vpdsnssspn hqgdgaaqas
      361 geqiqpsatt qetqqwllkn rfssytrlfs nfsgadllkl tkedlvqicg aadgirlyns
      421 lksrsvrprl tiyvcqeqps stalqgqpqa agsggesggg tpsvyhaiyl eemvasevar
      481 klasvfnipf hqinqvyrqg ptgihilvsd qmvqnfqdet cflfstvkae nndgihiilk
//
