LOCUS       NM_001033773            1517 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus ubiquitin-conjugating enzyme E2U (putative) (Ube2u),
            mRNA.
ACCESSION   NM_001033773 XM_355502 XM_884080 XM_914882 XM_923453
VERSION     NM_001033773.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1517)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1517)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. PMID: 29144450]
REFERENCE   3  (bases 1 to 1517)
  AUTHORS   Miyata,H., Castaneda,J.M., Fujihara,Y., Yu,Z., Archambeault,D.R.,
            Isotani,A., Kiyozumi,D., Kriseman,M.L., Mashiko,D., Matsumura,T.,
            Matzuk,R.M., Mori,M., Noda,T., Oji,A., Okabe,M.,
            Prunskaite-Hyyrylainen,R., Ramirez-Solis,R., Satouh,Y., Zhang,Q.,
            Ikawa,M. and Matzuk,M.M.
  TITLE     Genome engineering uncovers 54 evolutionarily conserved and
            testis-enriched genes that are not required for male fertility in
            mice
  JOURNAL   Proc Natl Acad Sci U S A 113 (28), 7704-7710 (2016)
   PUBMED   27357688
REFERENCE   4  (bases 1 to 1517)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB616918.1, BC172031.1, AL670290.13, AK133379.1 and AV266581.1.
            
            [WARNING] On Jul 9, 2024 this sequence was replaced by
            NM_001033773.5.
            
            On Nov 10, 2010 this sequence version replaced NM_001033773.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC150888.1, SRR5189685.193505.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN00849385
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-149               BB616918.1         2-150
            150-572             BC172031.1         142-564
            573-614             AL670290.13        10001-10042
            615-1061            BC172031.1         607-1053
            1062-1515           AK133379.1         982-1435
            1516-1517           AV266581.1         276-277
FEATURES             Location/Qualifiers
     source          1..1517
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 45.72 cM"
     gene            1..1517
                     /gene="Ube2u"
                     /note="ubiquitin-conjugating enzyme E2U (putative)"
                     /db_xref="GeneID:381534"
                     /db_xref="MGI:MGI:3588216"
     exon            1..381
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     CDS             316..1374
                     /gene="Ube2u"
                     /EC_number="6.3.2.19"
                     /codon_start=1
                     /product="ubiquitin-conjugating enzyme E2 U"
                     /protein_id="NP_001028945.2"
                     /db_xref="CCDS:CCDS18390.2"
                     /db_xref="GeneID:381534"
                     /db_xref="MGI:MGI:3588216"
                     /translation="MYSKAYILLEREFRELKRDTRKDITAYPVSDDMMNWKAEIEGLR
                     NSVCEGLVFYLTLEFSQEYNSVPPNVKFTTIPFHPNVDPYTGKPSIDFLDKPGKWNTN
                     YTVLSILLDLQMLLSYPVLKNPVNLEAAQLLIRNASTYKMVIQELLPPALPKRESSLV
                     IPEKPQDRVRVIKTISFNDYYKTWSQIATTKVAEHSRNPFVGDPHFMGQYYKWKQQDR
                     QNQVQWESKFALSKWQTARKKIMAQEKSNHYNQVIGIYPSPSELSFEYEIEEEEEEEE
                     EEEEEEEEEEEEEEKEEEEEEPRIYQIPQEWPEEHDSKESWEEEADHLVSWTNGLDEE
                     SLNYEYFDNVKNYENLGN"
     exon            382..463
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     exon            464..556
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     exon            557..654
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     exon            655..775
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     exon            776..824
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     exon            825..913
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     exon            914..995
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1093
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..1517
                     /gene="Ube2u"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaaagagaa cttggcagtg ctgcttcggg tttgcatttt tttcctcttg gccagccaac
       61 aactccggca tctctcaagt ggtccccaag tttgtctagg ggtggaagct gagacagccc
      121 agataggaaa gaccccagtc ttccttcggg aagttcccgt ctggaggagt cagaaaagaa
      181 agtcactgtt aaatcctaat cttagcagtt acttgactac ggagtgagta accgttaacc
      241 aggggtcaga gggtgaccgg agacctcagt caggaactct gccctgagta aaccaagaca
      301 agtagcaacc tcagtatgta ctccaaagct tacatcttgc tggaaagaga attcagggag
      361 ttaaaacgtg acacaagaaa ggatattact gcttatcctg taagtgatga tatgatgaat
      421 tggaaagctg agattgaagg tcttcgcaat tcagtttgtg aaggacttgt tttctacctg
      481 acattagagt tttcacaaga gtacaattct gttcctccaa atgtgaaatt tacaacaatt
      541 ccttttcatc caaatgtaga cccatatacc ggtaaaccca gtatagactt tttggacaag
      601 cctggcaagt ggaacacgaa ttatacagta ctcagcatct tacttgatct acagatgttg
      661 ctttcttacc ctgtcctaaa aaatccagtg aacttggagg cagcccaact gctgattaga
      721 aatgcgtcta cgtataaaat ggtaattcag gaacttttgc cgccagcatt accaaaaaga
      781 gagagcagcc tggtgatacc tgaaaagcca caggatcgag tcagggtaat taaaacaatc
      841 tcatttaatg attactacaa gacatggtct cagatagcca cgacaaaagt cgcagaacac
      901 tccagaaacc catttgttgg agatccacat ttcatgggac agtattacaa atggaagcaa
      961 caggatcggc agaatcaagt gcaatgggag tccaagtttg cactctcaaa gtggcagact
     1021 gctaggaaaa aaataatggc tcaggaaaag agcaatcact acaaccaagt gataggtatc
     1081 tacccatctc cgagtgaact ttcttttgaa tatgaaatag aagaagaaga agaagaagaa
     1141 gaagaggagg aggaggagga ggaggaggaa gaagaagaag aagaaaaaga agaagaagaa
     1201 gaagaaccaa ggatttatca aatacctcag gagtggccag aagaacatga ttcaaaagaa
     1261 tcctgggaag aggaagcaga ccacctggtc tcctggacca atggtcttga tgaagaatct
     1321 ttgaactatg agtactttga caacgtaaag aactatgaga acttgggcaa ctaacacaca
     1381 aggactttac acactgccct attacagtgc agtctcaggg aacagtttta ggagatgctc
     1441 aggacctggc ttctgctctc taccccagtt gatctcatct ttctggaagc acaaaataga
     1501 aaatacaagt ataagcc
//
