LOCUS       NM_001357043            3457 bp    mRNA    linear   ROD 04-APR-2024
DEFINITION  Mus musculus ubiquitin-activating enzyme, Chr Y (Uba1y), mRNA.
ACCESSION   NM_001357043 XM_006531582
VERSION     NM_001357043.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3457)
  AUTHORS   Kazi,S., Castaneda,J.M., Savolainen,A., Xu,Y., Liu,N., Qiao,H.,
            Ramirez-Solis,R., Nozawa,K., Yu,Z., Matzuk,M.M. and
            Prunskaite-Hyyrylainen,R.
  TITLE     MRNIP interacts with sex body chromatin to support meiotic
            progression, spermatogenesis, and male fertility in mice
  JOURNAL   FASEB J 36 (9), e22479 (2022)
   PUBMED   35920200
REFERENCE   2  (bases 1 to 3457)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3457)
  AUTHORS   Yao,C.J., Xu,W.J., Gong,X.L., Zhou,Y., Yan,Z.Q., Zhu,Z.J.,
            Wang,Z.X., Li,Q.L., Guo,X.B., Wang,L.Y., Ma,D. and Qiao,Z.D.
  TITLE     The role of Dby mRNA in early development of male mouse zygotes
  JOURNAL   Asian J Androl 12 (4), 567-577 (2010)
   PUBMED   20543856
REFERENCE   4  (bases 1 to 3457)
  AUTHORS   Alton,M., Lau,M.P., Villemure,M. and Taketo,T.
  TITLE     The behavior of the X- and Y-chromosomes in the oocyte during
            meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary
  JOURNAL   Reproduction 135 (2), 241-252 (2008)
   PUBMED   18239052
REFERENCE   5  (bases 1 to 3457)
  AUTHORS   Sandstedt,S.A. and Tucker,P.K.
  TITLE     Evolutionary strata on the mouse X chromosome correspond to strata
            on the human X chromosome
  JOURNAL   Genome Res 14 (2), 267-272 (2004)
   PUBMED   14762062
REFERENCE   6  (bases 1 to 3457)
  AUTHORS   Mitchell,M.J., Woods,D.R., Wilcox,S.A., Graves,J.A. and Bishop,C.E.
  TITLE     Marsupial Y chromosome encodes a homologue of the mouse Y-linked
            candidate spermatogenesis gene Ube1y
  JOURNAL   Nature 359 (6395), 528-531 (1992)
   PUBMED   1406968
REFERENCE   7  (bases 1 to 3457)
  AUTHORS   Jackson-Grusby,L., Kuo,A. and Leder,P.
  TITLE     A variant limb deformity transcript expressed in the embryonic
            mouse limb defines a novel formin
  JOURNAL   Genes Dev 6 (1), 29-37 (1992)
   PUBMED   1339380
REFERENCE   8  (bases 1 to 3457)
  AUTHORS   Disteche,C.M., Zacksenhaus,E., Adler,D.A., Bressler,S.L.,
            Keitz,B.T. and Chapman,V.M.
  TITLE     Mapping and expression of the ubiquitin-activating enzyme E1 (Ube1)
            gene in the mouse
  JOURNAL   Mamm Genome 3 (3), 156-161 (1992)
   PUBMED   1617221
REFERENCE   9  (bases 1 to 3457)
  AUTHORS   Kay,G.F., Ashworth,A., Penny,G.D., Dunlop,M., Swift,S.,
            Brockdorff,N. and Rastan,S.
  TITLE     A candidate spermatogenesis gene on the mouse Y chromosome is
            homologous to ubiquitin-activating enzyme E1
  JOURNAL   Nature 354 (6353), 486-489 (1991)
   PUBMED   1749428
REFERENCE   10 (bases 1 to 3457)
  AUTHORS   Mitchell,M.J., Woods,D.R., Tucker,P.K., Opp,J.S. and Bishop,C.E.
  TITLE     Homology of a candidate spermatogenic gene from the mouse Y
            chromosome to the ubiquitin-activating enzyme E1
  JOURNAL   Nature 354 (6353), 483-486 (1991)
   PUBMED   1684224
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF150963.1 and AC139318.5.
            
            On Oct 17, 2017 this sequence version replaced XM_006531582.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF150963.1, AK030031.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-378               AF150963.1         1-378
            379-379             AC139318.5         37073-37073         c
            380-3457            AF150963.1         380-3457
FEATURES             Location/Qualifiers
     source          1..3457
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="Y"
                     /map="Y"
     gene            1..3457
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /note="ubiquitin-activating enzyme, Chr Y"
                     /db_xref="GeneID:22202"
                     /db_xref="MGI:MGI:98891"
     exon            1..102
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..3279
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /EC_number="6.2.1.45"
                     /note="ubiquitin-activating enzyme E1 Y;
                     ubiquitin-activating enzyme E1, Chr Y 1"
                     /codon_start=1
                     /product="ubiquitin-like modifier-activating enzyme 1 Y"
                     /protein_id="NP_001343972.1"
                     /db_xref="CCDS:CCDS30540.1"
                     /db_xref="GeneID:22202"
                     /db_xref="MGI:MGI:98891"
                     /translation="MSSSVLSKKRKVSGPDSSLDSSWSPTYSVMFGVPPGPTNEMSKN
                     KEMDIDESLYSRQLYVLGHEAMKHLQASSVLISGLQGLGVEIAKNIILGGVKAVTLHD
                     QGIAQWADLSSQFCLREEDIGKNRAEISQPRLAELNSYVPVFAYTGPLIEEFLSGFQV
                     VVLTNTPLEYQLQVGEFCHSHGIKLVVADTRGLVGQLFCDFGEEMILTDSNGEQPLSA
                     MVSMITKENPGIVTCLEDSRHGFESGDFISFTEVQGMSELNGIGPIEIKVLGPYTFSI
                     CDTSSFSEYIRGGIVSQVKVPRKINFKPLLASLAEPEFVVTDFAKCCHPAQLHIGFQA
                     LHQFCTQHSRPPRPHNEEDAEELVTLAQSVNAQALPAVQQDCLDIDLIRKLAYVAAGD
                     LAPMNAFFGGLAAQEVMKACSGKFMPIRQWLYFDALECLPEHRVAFMEDKCLPHQNRY
                     DGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEDGEITVTDMDTIE
                     KSNLNRQFLFRPWDITKLKSETAAAAVRDINPHIRIFSHQNRVGPETEHVYDDDFFQK
                     LDGVANALDNVDARLYVDRRCVYYRKPLLESGTLGTKGNVQVVVPFLTESYSSSQDPP
                     EKSIPICTLKNFPNAIEHTVQWARDEFEGLFKQSAENVNQYLTDPKFMERTLQLAGTQ
                     PLEVLEAIHCSLVLQRPQTWADCVTWAYQHWHTQYSHNIQQLLHNFPPAQLTSSGALF
                     WSGPKRCPHPLTFDINNPLHLDYVMAAANLFAQTYGLGGSQDCAVVAKLLQSLPVPKF
                     APKSGIRIHVSEQELQSTSATTIDDSHLEELKTALPTPDKLLGFKMYPIDFEKDDDSN
                     FHMDFIVAASNLRAENYGISPADRHKSKLIAGKIIPAIATTTSAIVGLVCLELYKVVQ
                     GHQQLESYKNSFINLALPLFSFSAPLAPECHQYYDQEWTLWDRFDVQGLQPSGEEMTL
                     KQFLDYFKTEHKLEVIMLSQGVSMLYSVFMPASKLKERLDQPMTEIVSCVSKQKLGHH
                     VKSLVFELCCNSDSGDDIEVPYVRYIIR"
     exon            103..219
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            220..275
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            276..444
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            445..579
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            580..686
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            687..777
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            778..910
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1008
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1009..1155
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1332
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1333..1437
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1518
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1519..1674
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1675..1840
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            1841..2037
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2038..2102
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2103..2298
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2299..2373
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2374..2566
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2567..2655
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2656..2748
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2749..2940
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            2941..3042
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            3043..3143
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
     exon            3144..3441
                     /gene="Uba1y"
                     /gene_synonym="A1s9Y-1; Sby; Ube-2; Ube1ay; Ube1y;
                     Ube1y-1; Ube1y1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcattttgt ggaaggagtt tcccgagaga aactggctgc tggccaggga cttgaaggtg
       61 gaggctgctc cgttctggga ccggatcctc gaggaagagg agatgtccag ctcagtcctg
      121 tccaagaaac gcaaagtgtc tggacctgac tctagtctgg attctagttg gtctcctacc
      181 tattctgtga tgtttggcgt gcccccaggg ccaaccaacg aaatgtcaaa aaataaggaa
      241 atggacatag atgaaagcct ttactcccgc cagctgtatg tactcggcca tgaggcaatg
      301 aagcatctcc aggcttccag tgtactgata tcaggcctgc agggtctggg tgtggaaatt
      361 gccaagaata tcatccttgg tggggtcaag gctgtcactc tccatgatca gggcattgcc
      421 cagtgggctg atctgtcttc ccagttctgc ctacgtgagg aagatattgg taaaaaccga
      481 gctgagatat cccaaccacg ccttgctgaa ctcaacagtt acgttcctgt gtttgcctac
      541 actggacctc taattgagga gttccttagt ggttttcagg tagtggttct taccaacact
      601 cctttggaat atcagctgca ggtgggtgaa ttctgccata gccacggaat caagctggta
      661 gtagcagaca ctcggggcct agttggacaa ctcttctgtg actttggaga ggaaatgatt
      721 ctcactgatt caaatggaga acagccactc agtgccatgg tttcaatgat cactaaggag
      781 aatccaggga ttgtcacctg cctggaggac tcccggcatg gatttgaaag tggtgacttt
      841 atctctttca cagaagttca gggcatgagt gaactcaatg gcattggtcc catagagatc
      901 aaagttctgg gtccctatac ctttagtatc tgtgatacct ccagcttctc tgagtacatc
      961 cgtggaggca ttgtcagtca agtgaaagta cctcggaaga tcaattttaa acccctactt
     1021 gcctcgctgg cagagccaga gtttgtggtc acagattttg ctaagtgctg tcatcctgct
     1081 cagctccaca ttggcttcca ggccctgcat cagttctgta ctcagcacag caggcctcct
     1141 cggccccata atgaggagga tgctgaggaa ttggtgacct tagcccaatc tgtgaatgct
     1201 caagctttgc cagcagttca gcaggattgc ctggacatcg accttatccg gaagttggcc
     1261 tatgtagcag ctggggacct ggcacccatg aatgcctttt ttggtggttt ggctgcccag
     1321 gaggtcatga aggcttgttc tggaaagttt atgcccatta ggcagtggct gtactttgat
     1381 gcccttgaat gtctcccaga gcacagagtg gccttcatgg aagataagtg cctgccacac
     1441 cagaaccgtt atgatgggca agtggctgta tttggatcag acctacaaga gaagcttggc
     1501 aagcagaaat acttcctggt aggtgcaggt gccattggct gtgagctgct caagaacttt
     1561 gccatgattg gcctcggctg tggggaggat ggagaaatca cagttacaga catggacacc
     1621 attgagaagt caaacctgaa caggcagttt ctcttccgtc cctgggacat cacaaaatta
     1681 aagtctgaga ctgctgctgc agcagtgcgt gacataaatc cacacatcag gatattcagc
     1741 caccagaatc gagtaggccc agagacagaa cacgtctatg atgatgactt cttccaaaag
     1801 ctggatggtg tggccaatgc cctagacaat gtggatgctc gattatacgt ggaccgccgt
     1861 tgtgtttact atcgtaagcc tctgctggaa tcaggcacgc tgggcaccaa gggcaacgtg
     1921 caggtggttg ttcccttctt gacagaatct tacagctcaa gccaggaccc acctgagaaa
     1981 tccatcccca tctgcacact gaagaacttc cctaatgcca ttgagcacac cgtgcagtgg
     2041 gctcgggatg agtttgaagg gctcttcaag cagtcagctg aaaatgttaa ccaatacctc
     2101 acggacccca agttcatgga gcggacactg cagctagccg gcacccagcc tttggaagta
     2161 ctggaggcca tacactgcag cctggtcctg cagaggccac agacttgggc cgactgtgtg
     2221 acttgggcct accagcactg gcacacccag tattctcaca acatccagca gttgctgcac
     2281 aacttccctc cagcacagct tacgagctct ggagcacttt tttggtcagg accaaaacgc
     2341 tgtccacatc ctctcacctt tgacataaac aatcccctgc atctggatta tgtgatggct
     2401 gctgccaacc tgtttgctca gacatacgga ctaggagggt cccaggactg tgctgtggtg
     2461 gccaaactcc tgcagtctct gccagtcccc aagtttgctc ccaagtctgg catcaggatc
     2521 catgtttctg agcaggagct gcagagtacc agtgccacca ccattgatga cagccacctg
     2581 gaggaactca agactgcact tcctactcca gacaagctgc ttggattcaa gatgtacccc
     2641 attgactttg agaaggatga cgacagcaac tttcacatgg atttcattgt ggcagcatcc
     2701 aacctccgag cagaaaacta tggcatttcc ccagcagacc ggcataagag caaactgatt
     2761 gcaggcaaga tcatcccagc cattgcaacc accacatctg ctatagttgg ccttgtgtgt
     2821 ctggagctgt acaaggtggt tcagggccac caacaactgg agtcttataa aaacagtttt
     2881 atcaacttgg ctctgccttt gtttagcttt tctgcacctc tggctccaga gtgtcatcag
     2941 tactatgatc aagagtggac actgtgggat cgctttgatg tgcaaggact gcaacctagc
     3001 ggtgaggaga tgaccttgaa gcagtttcta gactacttta agacagagca caagctggaa
     3061 gtcatcatgc tgtcccaggg tgtgtccatg ctctattctg tctttatgcc agccagcaag
     3121 ctcaaagaac ggttggatca gccgatgaca gagattgtga gctgtgtgtc aaagcaaaaa
     3181 ctgggccatc atgtgaagtc acttgtgttt gagctgtgct gcaacagtga cagtggagac
     3241 gacatagagg ttccttatgt acgatacatc atccgctgat ctcttactga ctccgttctt
     3301 tcagatctct cagtctatat caaaaccttt ctagttatga ggaaacctca gtttgaacct
     3361 ccttgttcct aagaactttt tagtgctgtt tttacattgt taagaactga aattcataat
     3421 aataaatttt cagcctgtga aaaaaaaaaa aaaaaaa
//
