LOCUS       NM_001305045            3090 bp    mRNA    linear   ROD 08-FEB-2023
DEFINITION  Mus musculus UDP-N-acetylglucosamine pyrophosphorylase 1 (Uap1),
            transcript variant 1, mRNA.
ACCESSION   NM_001305045
VERSION     NM_001305045.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3090)
  AUTHORS   Yang S, Jin S, Xian H, Zhao Z, Wang L, Wu Y, Zhou L, Li M and Cui
            J.
  TITLE     Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to
            facilitate innate immune response
  JOURNAL   Mol Cell 83 (2), 298-313 (2023)
   PUBMED   36603579
  REMARK    GeneRIF: Metabolic enzyme UAP1 mediates IRF3 pyrophosphorylation to
            facilitate innate immune response.
REFERENCE   2  (bases 1 to 3090)
  AUTHORS   Cibi DM, Mia MM, Guna Shekeran S, Yun LS, Sandireddy R, Gupta P,
            Hota M, Sun L, Ghosh S and Singh MK.
  TITLE     Neural crest-specific deletion of Rbfox2 in mice leads to
            craniofacial abnormalities including cleft palate
  JOURNAL   Elife 8, e45418 (2019)
   PUBMED   31241461
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3090)
  AUTHORS   Yi J, Lu L, Yanger K, Wang W, Sohn BH, Stanger BZ, Zhang M, Martin
            JF, Ajani JA, Chen J, Lee JS, Song S and Johnson RL.
  TITLE     Large tumor suppressor homologs 1 and 2 regulate mouse liver
            progenitor cell proliferation and maturation through antagonism of
            the coactivators YAP and TAZ
  JOURNAL   Hepatology 64 (5), 1757-1772 (2016)
   PUBMED   27531557
REFERENCE   4  (bases 1 to 3090)
  AUTHORS   Bebee TW, Park JW, Sheridan KI, Warzecha CC, Cieply BW, Rohacek AM,
            Xing Y and Carstens RP.
  TITLE     The splicing regulators Esrp1 and Esrp2 direct an epithelial
            splicing program essential for mammalian development
  JOURNAL   Elife 4, e08954 (2015)
   PUBMED   26371508
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 3090)
  AUTHORS   Eddleston J, Murdoch JN, Copp AJ and Stanier P.
  TITLE     Physical and transcriptional map of a 3-Mb region of mouse
            chromosome 1 containing the gene for the neural tube defect mutant
            loop-tail (Lp)
  JOURNAL   Genomics 56 (2), 149-159 (1999)
   PUBMED   10051400
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BM947026.1, AK049519.1, AK081690.1, AK036243.1, AK047566.1,
            AA646755.1, AC123650.7, AC119893.9 and AI467637.1.
            
            [WARNING] On May 5, 2023 this sequence was replaced by
            NM_001305045.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147139.1, AK036243.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                BM947026.1         1-18
            19-1160             AK049519.1         2-1143
            1161-1161           AK081690.1         1115-1115
            1162-1616           AK049519.1         1145-1599
            1617-1619           AK036243.1         1546-1548
            1620-2302           AK049519.1         1600-2282
            2303-2369           AK047566.1         2246-2312
            2370-2400           AA646755.1         161-191
            2401-2556           AC123650.7         162765-162920
            2557-2639           AC119893.9         179371-179453       c
            2640-2683           AA646755.1         431-474
            2684-2700           AC119893.9         179310-179326       c
            2701-3090           AI467637.1         1-390               c
FEATURES             Location/Qualifiers
     source          1..3090
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1"
     gene            1..3090
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /note="UDP-N-acetylglucosamine pyrophosphorylase 1"
                     /db_xref="GeneID:107652"
                     /db_xref="MGI:MGI:1334459"
     exon            1..215
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            216..538
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            539..743
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            744..919
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1092
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1286
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1287..1427
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1616
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1667
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1668..1734
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..3084
                     /gene="Uap1"
                     /gene_synonym="AgX; AGX-1; AGX-2; AGX1; ESTM38; SPAG2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgacgtgtc gggccggcag gcttccgctc cgcccctggg ccgcagccac tcaccgcggc
       61 gggaggggcc gggtggccgg ggcccgcgct cccctcggcc gctgctcgtg gcccgccccg
      121 ccgccccggc ccctcggatg acagtatata ttccaggcgg gcgcgggaca cgggcgagta
      181 gccgagccga aggagccgcg ggattgtcga gggagctctc cctactctgt ttttaccaag
      241 cttcactacc agagcactat gaatgtcaat gacctcaaac aaaggctgtc ccaagctggg
      301 caagagcacc tgctgcagtt ctggaatgag ctgtccgaag cccagcaggt agaactttat
      361 atggagctcc aggccatgaa ctttgaagag ctgaactcct ttttccggaa ggccattggt
      421 gaatttgatc gatcctctca ccaagaaaag gtggacgcac gaatggagcc tgtgccccgg
      481 caggttttgg gcagtgctac cagagatcaa gagcagctgc aggcctggga aagtgaagga
      541 ctttctcaga tttctcagaa caaagtagca gttcttcttc tagctggtgg gcaggggaca
      601 agacttggag tctcatatcc caagggcatg tatgatgttg gcttgccatc ccacaagacg
      661 ctttttcaga ttcaagcaga acgtattctg aaactccagc agttagctga aaaacaccat
      721 ggcaacaagt gcaccatccc atggtatata atgaccagcg gcagaacaat ggaatcaacg
      781 aaggagttct tcacaaagca caagttcttt ggtttaaaaa aggagaatgt ggtgtttttc
      841 cagcagggaa tgctgcctgc tatgagtttt gatgggaaaa ttatcttgga agagaaaaac
      901 aaagtgtcta tggctccaga tgggaatggt ggtctctacc gggctcttgc agcccaaaac
      961 attgtggagg acatggagca aagaggcatc tgcagtattc atgtctattg tgtggacaac
     1021 atattggtaa aagtggctga cccgcggttc attggattct gcattcagaa aggagcagac
     1081 tgtggggcaa aggtggtaga gaaaacgaat cccacagagc cagttggagt ggtttgccgg
     1141 gtggatggag tataccaggt ggtagaatac agcgagatct ctctggcaac agctcaaagg
     1201 cgaagttcag atggacggct gctgttcaat gcagggaaca ttgccaatca cttcttcact
     1261 gtcccgttcc tgaaagatgt tgtcaatgtt tatgaacctc agttgcagca ccatgtggct
     1321 caaaagaaga ttccatatgt ggactcccag gggcacttca ttaagccaga caagccaaat
     1381 ggaataaaga tggaaaaatt tgtctttgac atcttccagt ttgcaaagaa gtttgtggtg
     1441 tatgaagtat tacgggaaga tgagttttcc ccgctcaaga atgcagacag tcagaacggg
     1501 aaggacaacc cgaccacagc aaggcatgct ttgatgtccc ttcaccactg ctgggtcctc
     1561 aatgccgggg gacacttcat agatgagaat ggctctcgcc tcccagccat cccccgcagt
     1621 gctacaaatg gaaagtcaga ggccatcaca gctgatgtca atcacaactt gaaagatgcc
     1681 aatgatgtac cgatccagtg tgaaatctct cccctcatct cttatgctgg agagggcctt
     1741 gaaggttatg tggcagataa agagttccat gcaccgctaa tcatcgatga gaatggagtt
     1801 catgagctgg tgaaaaatgg catataaatc ctaacgggcc acatagggag ccgttgtttt
     1861 ggtagatcaa ttgtgaacct gtgggacctg tcctggacag ctgaagtttg gacgtgcatc
     1921 gagtctcatt cgcttgctag tgtctgctaa gcaacacaga cttcccagac ccagatgact
     1981 ggagttcatt tttaaaagca tttttttttt cttttttgtg attctcaact ctctgaaggt
     2041 cttatttata ttttttaact atataagttc ttccaagcca aggctcatat tggccaccca
     2101 ggaaacttcg tcagcttgac tctggttgga tgttcagcat gacttcactt gaagctggaa
     2161 gcatttgttt ttgaagttgt acatattgat aagtcagcgt atgtgtcaga ggtttctatg
     2221 gtactaaaat tttgttttat tttatcaagc attaaagttt tttaagaaaa taactggaca
     2281 gcaaaataaa attatcttct tgtcactgcc ttgtttctac cttaagaaaa ttctattggc
     2341 aaaatacaaa acttgggaag tgttttgaga taatgcataa aaacaagtgc gtggagtcac
     2401 ggctttcttc agcaggcagc cgacgttggg ttttgtcttc tgtcactctc cagtctctac
     2461 caaatgtttt tcccagatgc aaagggcact tggctcagtt ggagacactt ttggtacctg
     2521 gttgggcaag tggggtggta ctaataccgt aaagcagatc catagcaaat gtgtggagta
     2581 acctcctaca gcaaggagtg accagccagt gtcctccata gcaaatgtgt ggagtaactc
     2641 ctacagcaag gagtgaccag ccagtgtcct ccatagcaaa tgtgtggagt aactcctaca
     2701 gcaaggagtg accagccagt gtcctccata gcaaatgtgt ggagtaacct cctacagcaa
     2761 ggagtgacca gccagtgtcc tccatagcaa atgtgtggag taacctccta cagcaaggag
     2821 tgaccagcca gtgtcctcca tagcaaatgt gtggagtaac ctcctacagc aaggagtgac
     2881 cagccagtgt cccaggattt aaggctgaga ggcatgctta aatcagttat ttacctattg
     2941 tccgtacata tcttgtagca cttaaaactt aatcactgca attctgatct ttttaaaatt
     3001 ataagattga aaaagagcgg caaacgtgaa tcttcaatgt gtaccagaag tcatgattgt
     3061 tgataaacca tttatttaaa agttaaaaaa
//
