LOCUS       NM_001416553             466 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus cDNA sequence U90926 (U90926), mRNA.
ACCESSION   NM_001416553
VERSION     NM_001416553.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Sabikunnahar,B., Caldwell,S., Varnum,S., Hogan,T., Lahue,K.G.,
            Rathkolb,B., Gerlini,R., Dragano,N.R.V., Aguilar-Pimentel,A.,
            Irmler,M., Sanz-Moreno,A., da Silva-Buttkus,P., Beckers,J.,
            Wolf,E., Gailus-Durner,V., Fuchs,H., Hrabe de Angelis,M.,
            Ather,J.L., Poynter,M.E. and Krementsov,D.N.
  CONSRTM   German Mouse Clinic Consortium
  TITLE     LncRNA U90926 is dispensable for the development of
            obesity-associated phenotypes in vivo
  JOURNAL   Physiol Rep 12 (1), e15901 (2024)
   PUBMED   38171546
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Graham,M.L., Li,M., Gong,A.Y., Deng,S., Jin,K., Wang,S. and
            Chen,X.M.
  TITLE     Cryptosporidium parvum hijacks a host's long noncoding RNA U90926
            to evade intestinal epithelial cell-autonomous antiparasitic
            defense
  JOURNAL   Front Immunol 14, 1205468 (2023)
   PUBMED   37346046
  REMARK    GeneRIF: Cryptosporidium parvum hijacks a host's long noncoding RNA
            U90926 to evade intestinal epithelial cell-autonomous antiparasitic
            defense.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 466)
  AUTHORS   Sabikunnahar,B., Caldwell,S., Varnum,S., Hogan,T., Cooper,A.,
            Lahue,K.G., Bivona,J.J., Cousens,P.M., Symeonides,M., Ballif,B.A.,
            Poynter,M.E. and Krementsov,D.N.
  TITLE     Long Noncoding RNA U90926 Is Induced in Activated Macrophages, Is
            Protective in Endotoxic Shock, and Encodes a Novel Secreted Protein
  JOURNAL   J Immunol 210 (6), 807-819 (2023)
   PUBMED   36705532
  REMARK    GeneRIF: Long Noncoding RNA U90926 Is Induced in Activated
            Macrophages, Is Protective in Endotoxic Shock, and Encodes a Novel
            Secreted Protein.
REFERENCE   4  (bases 1 to 466)
  AUTHORS   Chen,J., Jin,J., Zhang,X., Yu,H., Zhu,X., Yu,L., Chen,Y., Liu,P.,
            Dong,X., Cao,X., Gu,Y., Bao,X., Xia,S. and Xu,Y.
  TITLE     Microglial lnc-U90926 facilitates neutrophil infiltration in
            ischemic stroke via MDH2/CXCL2 axis
  JOURNAL   Mol Ther 29 (9), 2873-2885 (2021)
   PUBMED   33895326
  REMARK    GeneRIF: Microglial lnc-U90926 facilitates neutrophil infiltration
            in ischemic stroke via MDH2/CXCL2 axis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC125542.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U90926.1, SRR17253012.5061625.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-59                AC125542.4         133623-133681       c
            60-123              AC125542.4         131114-131177       c
            124-177             AC125542.4         130350-130403       c
            178-213             AC125542.4         129427-129462       c
            214-466             AC125542.4         128224-128476       c
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 46.23 cM"
     gene            1..466
                     /gene="U90926"
                     /note="cDNA sequence U90926"
                     /db_xref="GeneID:57425"
                     /db_xref="MGI:MGI:1930915"
     exon            1..59
                     /gene="U90926"
                     /inference="alignment:Splign:2.1.0"
     exon            60..123
                     /gene="U90926"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..333
                     /gene="U90926"
                     /note="putative TNF-resistance related protein; U9-ORF
                     protein; endotoxic shock protective protein U9-ORF"
                     /codon_start=1
                     /product="endotoxic shock protective protein U9-ORF
                     precursor"
                     /protein_id="NP_001403482.1"
                     /db_xref="GeneID:57425"
                     /db_xref="MGI:MGI:1930915"
                     /translation="MKVVILMALLVLTAHCVPVSRFPGKIFLYCPFFNRKHCQRFCEF
                     FKICRKPPLSRRTTVVPSFPLTTEADLSLTGGPLTPDRRGDSR"
     exon            124..177
                     /gene="U90926"
                     /inference="alignment:Splign:2.1.0"
     exon            178..213
                     /gene="U90926"
                     /inference="alignment:Splign:2.1.0"
     exon            214..466
                     /gene="U90926"
                     /inference="alignment:Splign:2.1.0"
     regulatory      449..454
                     /regulatory_class="polyA_signal_sequence"
                     /gene="U90926"
                     /note="hexamer: AATAAA"
     polyA_site      466
                     /gene="U90926"
                     /note="major polyA site"
ORIGIN      
        1 gaatgaggct tcaaaagaac tcaagattac cagatactcc gtccttcctg gtcatactga
       61 taaagaaaaa tgaaggtggt gattctgatg gcccttcttg tgctcacagc tcactgtgta
      121 ccagtatcaa gattccctgg caagattttc ctctactgtc ctttcttcaa ccggaagcac
      181 tgccagaggt tctgtgaatt ctttaaaatc tgtaggaagc cgccactgag cagaagaact
      241 actgtggtcc catcattccc actcacaaca gaagctgacc tttctctgac tgggggtcct
      301 cttactcccg acaggcgggg agattcaaga tagtagggtt cctcacagcc cagaaaagcc
      361 tcttccccca cacagtgccc atgctacagt cggatcatgc ttccagctcc ttcctgcacc
      421 acagtgactc ctccctacct gatgtgtcaa taaaaagctt acatta
//
