LOCUS       NM_016792               2558 bp    mRNA    linear   ROD 05-AUG-2024
DEFINITION  Mus musculus thioredoxin-like 1 (Txnl1), mRNA.
ACCESSION   NM_016792
VERSION     NM_016792.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2558)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2558)
  AUTHORS   Wiseman,R.L., Chin,K.T., Haynes,C.M., Stanhill,A., Xu,C.F.,
            Roguev,A., Krogan,N.J., Neubert,T.A. and Ron,D.
  TITLE     Thioredoxin-related Protein 32 is an arsenite-regulated Thiol
            Reductase of the proteasome 19 S particle
  JOURNAL   J Biol Chem 284 (22), 15233-15245 (2009)
   PUBMED   19349280
  REMARK    GeneRIF: TRP32 was identified as a novel subunit of the 26 S
            proteasome.
            Erratum:[J Biol Chem. 2020 Jul 3;295(27):9267. doi:
            10.1074/jbc.AAC120.014712. PMID: 32620695]
REFERENCE   3  (bases 1 to 2558)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   4  (bases 1 to 2558)
  AUTHORS   Jimenez,A., Pelto-Huikko,M., Gustafsson,J.A. and Miranda-Vizuete,A.
  TITLE     Characterization of human thioredoxin-like-1: potential involvement
            in the cellular response against glucose deprivation
  JOURNAL   FEBS Lett 580 (3), 960-967 (2006)
   PUBMED   16438969
REFERENCE   5  (bases 1 to 2558)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 2558)
  AUTHORS   Lee,K.K., Murakawa,M., Takahashi,S., Tsubuki,S., Kawashima,S.,
            Sakamaki,K. and Yonehara,S.
  TITLE     Purification, molecular cloning, and characterization of TRP32, a
            novel thioredoxin-related mammalian protein of 32 kDa
  JOURNAL   J Biol Chem 273 (30), 19160-19166 (1998)
   PUBMED   9668102
  REMARK    Erratum:[J Biol Chem 1998 Oct 16;273(42):27755]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC102040.16.
            
            On Apr 28, 2007 this sequence version replaced NM_016792.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK029807.1, AK051698.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-284               AC102040.16        186469-186752       c
            285-381             AC102040.16        176604-176700       c
            382-555             AC102040.16        173746-173919       c
            556-678             AC102040.16        171272-171394       c
            679-748             AC102040.16        169837-169906       c
            749-921             AC102040.16        168442-168614       c
            922-1026            AC102040.16        165975-166079       c
            1027-2558           AC102040.16        157194-158725       c
FEATURES             Location/Qualifiers
     source          1..2558
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 37.06 cM"
     gene            1..2558
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /note="thioredoxin-like 1"
                     /db_xref="GeneID:53382"
                     /db_xref="MGI:MGI:1860078"
     exon            1..284
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            285..381
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            382..555
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            556..678
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            679..748
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            749..921
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1026
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..2558
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1230..1235
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /note="hexamer: AATAAA"
     polyA_site      1253
                     /gene="Txnl1"
                     /gene_synonym="32kDa; TRP32; Txnl"
                     /note="major polyA site"
ORIGIN      
        1 tcctccccct ccgctcgcct gctccctggc gtgactcggc actcgcagct ccgggaggac
       61 acgtcgtggt cgccgttccc gcccaggccc cggcctcctg cagcccgtct ccggcctctc
      121 tcgggctctg tgcttcagtt ttgaggccgg aagcgtcgcg gccgccctgc cgggctctct
      181 gtgaggatgg tgggagtgaa gccggtcggg agcgatccag atttccagcc ggagctgagc
      241 ggggcgggct ccagacttgc cgtggtcaag ttcaccatga gagggtgtgg accgtgtctt
      301 cggattgccc cggcgttcag ctctatgagt aataagtacc cacaggcagt cttcttggaa
      361 gtagatgtgc atcagtgcca gggaacagct gccaccaaca acatatcagc aacacctacg
      421 tttttgtttt ttcgaaacaa agtgagaatc gatcagtatc aaggagcaga tgctgtggga
      481 ctagaagaga aaatcaagca gcacttagaa aatgatcctg gaagcaatga ggacgcagac
      541 attccaaagg gctatatgga tttaatgcct tttattaaca aagctggttg tgaatgtctt
      601 aatgaaagtg atgagcacgg ctttgacaac tgtttacgaa aagacatgtc cttcttggag
      661 tctgactgtg atgagcagct ccttattact gtggcattca atcagcctgt taagctttat
      721 tccatgaagt ttcaaggacc agataacggt cagggtccta aatatgtaaa aatttttatc
      781 aacctacccc gatctatgga ttttgaggag gcggaaagga gtgagccaac tcaagctctg
      841 gaactgacag aagatgacat taaagaagat ggcattgttc ctcttcgtta tgttaaattt
      901 cagaatgtca acagtgtaac tttatttgtt cagtctaatc aaggagaaga agaaacaacg
      961 agaatttcat attttacttt cattggtact ccagtccagg caacaaatat gaatgacttc
     1021 aaacgagtgg ttggcaaaaa aggggaaagc cattagggta caaagacact ggaagactta
     1081 ctgcagtcag acttgcagct cctggataat tgcttgattc tcttcggaaa ctgttaatct
     1141 tttatttgtt gccagtacca ataaatcatt gcttttgttc agatggcatc actagtgttt
     1201 gtagtgtaat cgtgatacat gcagttgtaa ataaaagtca ctacttttgc caagcttaag
     1261 tcttcgtcat tctatataaa tgcattctct ctctttttat ttgaaaattt gctaacctct
     1321 tgttttagga gttgtgtcta gtatcacatt gactaaaagt tactctatct ctagaggaac
     1381 agaacgccac agggattagg agtactgtct atacacatgg agagtttaga caggatttga
     1441 aacctccatg tatgtgtaat gtttggatgc atggatttgg aatggttaac caagttcaag
     1501 tacattctga cttattttat caaaaagcat ttgggtatct aggctttaca aatttgttaa
     1561 aaaacccaat ttataaacac ccagtactct tacctatcac tggtagttaa cagatttaca
     1621 aatattttgg ttttaggtta gcttcactgt tgatatcctt gggtacctgc cttccaaatg
     1681 gtgggattgt aggcctgtac cactaaacct ggtctcatgc caagatttta actttctgca
     1741 taaacctaaa cattagagtc aactatttcc tttaataatg caggtattaa aactgaattc
     1801 agaaaaattt ggaaattata atacatggag attatttaat ttaaaaatta aaaaatatgg
     1861 aaaattagaa tcaaatctat tatctaaatt caccaaaaca ttcactctat atagatagag
     1921 aacatgattt aagcttaaaa tgagttgtcc cagctgtttg tttgaaagat cttccacaaa
     1981 agactggata agcaaatact tgttgttcta agcttttaaa acatttaata ttggcaaatt
     2041 taatgtttaa atactttatt ttgttttatg tttatgtgtg tttggcttcc atgtatgtgt
     2101 atattcgtgt gagtgagtgt ggtgcccagc agaggggtga cagctggtgg gaactgccat
     2161 gtgggtgatg ggaactgagc ccaggcctct ataagactgc tgctccatcc ccacacatta
     2221 atcttgtaat tcattatttt aaaagcatat ataagactaa taacttgtaa ttcatttaat
     2281 acatttgagg gcattcttac ctatatagtg cagaggtttg cctttggata ctaatgtact
     2341 tatacgtaat tatgagaaaa aaaaaaccaa actctggatg ttgttgaagt agtgttgaaa
     2401 tagtcctttt ctgaaacttg tgtcattaag taatgtttag ttcatgtgta tgtgagctca
     2461 gtaactggtc tgtgataatg tctgtatttt atgtatttca cagtttgttg acttaaagtg
     2521 aaagaaagac aaaaaaagta aacgtttata atacctgt
//
