LOCUS       NM_001310534            4062 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus thioredoxin domain containing 16 (Txndc16), transcript
            variant 1, mRNA.
ACCESSION   NM_001310534 XM_006519519
VERSION     NM_001310534.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4062)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY122029.1, AK046466.1 and CX209472.1.
            
            On Jul 15, 2015 this sequence version replaced XM_006519519.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052488.1, SRR1660813.89326.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                BY122029.1         1-31
            32-2536             AK046466.1         2-2506
            2537-2901           CX209472.1         189-553
            2902-4062           AK046466.1         2869-4029
FEATURES             Location/Qualifiers
     source          1..4062
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 22.77 cM"
     gene            1..4062
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /note="thioredoxin domain containing 16"
                     /db_xref="GeneID:70561"
                     /db_xref="MGI:MGI:1917811"
     exon            1..209
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            210..263
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            264..502
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             340..2802
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; thioredoxin domain-containing protein 16"
                     /codon_start=1
                     /product="thioredoxin domain-containing protein 16 isoform
                     1 precursor"
                     /protein_id="NP_001297463.1"
                     /db_xref="CCDS:CCDS79300.1"
                     /db_xref="GeneID:70561"
                     /db_xref="MGI:MGI:1917811"
                     /translation="MMSSGFSVFRAGVALVLMCSFYKSTEDSLPELTPQQYFSTLQPG
                     KASLVYFCQVGSLSNSVFLEELKEAVKPLQDYGISVAKVTCVEEEASRYCGEEEGLMK
                     AYLFRGNILLREFPTDILFDVNAIIAHVLFALLFNEVKYITTLEDLHSIENSLKGKSN
                     MIFSYVEAIGTPEHRAVMEAAFVYGTSYQFALTTEIALLENIGSESIEHAHLYFFHCK
                     LVLDLTEHCRRTLMEQPLTTLNIHVFVKTMNAPLLMEVAEDPQQVSTVHLQLGLPLVF
                     IISQRATQEADRRTAEWVAWHLLGKAGVLLLLRDSMDVNIPQHANVAFRRAEKDVPVE
                     FLVLNDVELIISHVKNNMHIEEIQEDEGEDMEGPDLAVEDDEVAGTVYRDRKKPLPLE
                     LSVELTEETFNTTVMTSDSIVLFYATWHAVSMAFLQSYIDVAIKLKGRSTILLTRINC
                     ADWSDICTKQNVTAFPVVKLYKEGESPVSYAGMLATKDLLKFIQLNKISCPVNIASIQ
                     EAEKYLRGELYKDLPSSASVSVLGLFSPAMASAKELFREAGKQLRGSVITGIYSEDDV
                     WILSNKYATTLPALLLARPKEGRIESVPLDTTLVQDMAQILANALLEAFPEITVENLP
                     TYLRFQRPLLLLFSGGSINPQYRNTILALVRQKQLDSFTPCWLNLKNTPVGRGILKAY
                     FGRLPPLPQLLLVNLHSGGQVYAFPSSQSVTEQSLVLWLKHLQAGLENPITVLSAQEW
                     KPPLPAFDFLNMMDAPTSQAPTKKVLECQKEAEVQESAELQPGDRSTARREPVEMLRI
                     KRWNTANWPKDTQEPFHHDKEL"
     exon            503..585
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            586..659
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            660..734
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            735..856
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            857..947
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1098
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1265
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1266..1326
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1327..1450
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1594
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1595..1654
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..1823
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1824..1960
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1961..2045
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2046..2184
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2345
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2346..2536
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2537..4062
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3847..3852
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3868
                     /gene="Txndc16"
                     /gene_synonym="5730420B22Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggagcctcgg gggttgtttt ttcgcccaag agactgattt tgcggaggca gtgccggccg
       61 tgggcggtga gcttctcagg taggcgtagt tgctttggga gccgccgtag ggaccagccc
      121 ctgccccgcc ttctgtcacc atctctactc tgatggcggg acgtgctgtc ctcagagacc
      181 tttcatctct gcacgagaat ctcaggcagc tggaggaaac acggggcgag gaaagcgaat
      241 gaagcaaagc gcgagcggaa actggatcgc ttcaagcagt agaacacggc agtgaagaaa
      301 acagacaagt ctcctggcac gcgtctccag gcacagctca tgatgtcttc tggcttcagt
      361 gtctttagag ctggtgttgc attggttttg atgtgcagtt tttacaagtc aactgaagac
      421 tctctcccag aactgactcc tcagcaatat ttcagcacac tgcagccagg aaaagcctca
      481 ttagtttatt tctgccaagt tggttctcta agtaactctg tgtttcttga agaactaaaa
      541 gaagctgtca agcctctcca ggactatggg atttcagttg caaaggttac ttgtgttgaa
      601 gaagaagcgt caaggtactg tggggaagaa gagggtttga tgaaagcgta tttattcaga
      661 ggcaacatac ttctcagaga attccccacg gacatcttgt ttgatgtgaa cgccatcatt
      721 gctcatgttc tctttgctct gctttttaat gaagtaaaat atattaccac cctggaagac
      781 cttcacagca tagaaaactc tctgaaagga aaatcaaata tgatattctc atacgtagaa
      841 gccatcggaa caccagagca tagagcagtc atggaagctg cttttgtgta tgggacctct
      901 taccagtttg ccttaaccac agaaattgct cttttagaaa atatcggctc tgagagtata
      961 gaacatgcac atctctactt ttttcattgt aaactggtct tggacttgac cgagcattgc
     1021 agaagaacac taatggaaca gccattgacc acactcaata ttcacgtatt tgtgaagaca
     1081 atgaacgcac ctctgttgat ggaagtggct gaagatcccc agcaggtctc aaccgttcat
     1141 ctacaactag gattgccact ggtttttatt atcagccagc gcgctaccca ggaggctgac
     1201 agaagaactg cggagtgggt ggcgtggcac cttctgggga aagcaggggt tctgctcttg
     1261 ttgagggact ccatggatgt taacattcct cagcacgcta atgtggcctt cagaagagca
     1321 gagaaggatg tgcctgtgga gtttctggtg ttgaatgatg ttgagttaat catttcccac
     1381 gtgaaaaata atatgcacat tgaagaaata caagaagatg aaggcgaaga catggagggc
     1441 ccagatctgg ctgttgaaga tgatgaggtg gcaggaactg tttacagaga taggaagaaa
     1501 ccactacctt tggagttgtc tgtggagcta acagaggaga cttttaatac aacggtcatg
     1561 acttctgaca gcatagtgct cttctatgct acctggcatg cagtatccat ggcatttcta
     1621 caatcctata ttgatgtggc aattaagttg aaaggcaggt ccaccatcct tctcaccaga
     1681 ataaattgtg cagattggtc tgatatatgt acgaagcaaa atgttactgc atttcccgtg
     1741 gtaaagttgt ataaggaagg cgagagccca gtgtcttatg ctggtatgtt ggcaactaaa
     1801 gatctcctga aatttatcca gttgaataag atctcctgtc cagtgaacat agcatctatc
     1861 caggaagcag aaaaatacct gcgtggggaa ttatataaag acctgcccag ctctgctagt
     1921 gtgtcagtac tggggctctt cagcccagcc atggcatcag caaaagaact tttcagggaa
     1981 gcaggaaagc agctgagagg ctctgtcatt acgggaattt attctgaaga tgatgtgtgg
     2041 atactgtcaa ataaatatgc tacaactctc ccagccctgc tactggccag gcctaaagaa
     2101 ggtagaatag agagtgtccc actagacacc accctggtac aagacatggc tcagatacta
     2161 gcaaatgcac tactggaagc atttccagaa atcactgtgg aaaatcttcc cacatattta
     2221 agatttcaga gaccgctact tctcttgttt agtggtggca gcataaaccc tcagtacagg
     2281 aacacgatcc tggcactggt gagacagaag cagctggatt cgtttacccc ttgctggtta
     2341 aatctgaaga acactcccgt ggggaggggc atcttgaagg catattttgg ccgtctgcca
     2401 ccacttcctc agctgctgtt ggtgaatctg cattcgggtg gccaagtgta tgcatttcct
     2461 tcatcccagt ctgtgacgga acaaagcctt gtgttgtggc tgaaacattt acaagcggga
     2521 ctagaaaatc ccatcacagt cttgtctgcc caggaatgga aacctcctct tcctgccttt
     2581 gattttctga atatgatgga cgctcctaca tcccaagctc ccacgaagaa agttctagag
     2641 tgtcagaaag aagcagaggt gcaggagagt gctgagctgc agcctggaga cagatcaaca
     2701 gccaggagag agccggtcga aatgctgaga ataaagcgct ggaacactgc caactggccc
     2761 aaagacacac aggagccttt tcaccacgac aaggagttat gagcgggcct cgtgggatgg
     2821 cctctctgtg gcacaggaaa cccgagatca aatctgtaaa ggaacaggac taaattatgc
     2881 catctctaga caagtgccat tgaatgggct tgtgatacaa atgacatgta aaatttctta
     2941 gtagttactc ttaaaaaccg taaaccgagc agataaaccc cagacagctt aattactacg
     3001 aaaatgttga catttacttt ttaatgtgaa gtcttcaaaa tacagtccat ttcacactta
     3061 atgcctttcc tcactaagga gatccgtttt tgagggctta tttgccatag gtggtacatg
     3121 acagttgtat agggcagttc actatcagac aaacaccagt gtgcttgacc tgggtctagc
     3181 catcctgtgc atttgaatca aattgggatg taactccact gaatcaccgt tgactctctg
     3241 gttgaatcat aactggcgtt tgtatttatt ttcttgtagc catattaaaa ccagtacttt
     3301 ccaggatatt tggcaagatg aagagacagt tttaatattt tgatttagtg atactattgg
     3361 catctacagg acagaggttg aggtgcccct acacccaacc actctacact gaatagatgg
     3421 atcctccatc aaagaattgt ctttctttta atgtcattag tcaccaaggt tgcataatta
     3481 gcaaccttgt agtagcctgt agcacagtgg gatctgcata tcttccgtct agttactgtg
     3541 tttgtaaatc tttggacatt aaaaatgagt ggctttcata tcctgactat taaaagtcat
     3601 tttaaaaaaa atattctttt gcattgtaca tgtttgagtg tttgacctgt gtgcattaaa
     3661 tgtactgcat gcattcctgg tgctcacaga gaacagaaga gggcattgga tgcctgcgga
     3721 ctggagttgt ggatagagta agctgccttg tggatgctag gaaccaaact ggggtcctct
     3781 gcaagagcca gtgctcttat ctgatgagcc atctctccag ccacaatttt tatactttga
     3841 agaagcaata aaagtctctt caaaaggact tacaatgtat gtaaatctgt gtgtgcactt
     3901 ctctgaatat acatatctgt acattttaag tctataagtg caactttcta tatacgtatt
     3961 tgtggattat aagggagtct taagtgagcc cttatctctc taagttagaa tgctaagttt
     4021 cagattaaat aggaattaaa tattgtgtta ctgtctccta gc
//
