LOCUS       NM_175150               1554 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus thioredoxin domain containing 15 (Txndc15), mRNA.
ACCESSION   NM_175150
VERSION     NM_175150.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1554)
  AUTHORS   Breslow,D.K., Hoogendoorn,S., Kopp,A.R., Morgens,D.W., Vu,B.K.,
            Kennedy,M.C., Han,K., Li,A., Hess,G.T., Bassik,M.C., Chen,J.K. and
            Nachury,M.V.
  TITLE     A CRISPR-based screen for Hedgehog signaling provides insights into
            ciliary function and ciliopathies
  JOURNAL   Nat Genet 50 (3), 460-471 (2018)
   PUBMED   29459677
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC062180.1.
            
            On Sep 25, 2004 this sequence version replaced NM_175150.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC062180.1, AK160051.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1554
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 30.06 cM"
     gene            1..1554
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /note="thioredoxin domain containing 15"
                     /db_xref="GeneID:69672"
                     /db_xref="MGI:MGI:1916922"
     exon            1..195
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..1163
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /note="thioredoxin domain-containing protein 15; disulfide
                     isomerase"
                     /codon_start=1
                     /product="thioredoxin domain-containing protein 15
                     precursor"
                     /protein_id="NP_780359.2"
                     /db_xref="CCDS:CCDS26553.1"
                     /db_xref="GeneID:69672"
                     /db_xref="MGI:MGI:1916922"
                     /translation="MQLLCWWQVLLWVLGLPAHGLEVAEDSGHPWREERPVPALQVGA
                     VYLHEEEVAQDHRDQARAAEPMEASLGPRGDPMVVLSVVPGAAEDQRSPEAHDGTCSA
                     QGEEDPSCGRENLFGLQGAGGFQDREEEYYAEPGVTEAEPVATEDANSTDSLKSPKVN
                     CEERNVTGLENFTLKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLP
                     RAFPTLGFLALDASQHSSLSTRFGTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIF
                     NQTGIEAKKNVVVTQADQMGPLPSTLIKTVDWLLVFSLFFLISFIMYATIRTESIRWL
                     IPGQEQEHAE"
     exon            196..671
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /inference="alignment:Splign:2.1.0"
     exon            672..835
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /inference="alignment:Splign:2.1.0"
     exon            836..966
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1527
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1509..1514
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /note="hexamer: AATAAA"
     polyA_site      1527
                     /gene="Txndc15"
                     /gene_synonym="2310047H23Rik; C5orf14; UNQ335"
                     /note="major polyA site"
ORIGIN      
        1 gcggccacgc ctgcgctctg ggctctcctc cccgtagtct ccctggggcg gggggtgcga
       61 ctccggttgc cggtgcgccg attttcttcc accgcggtgg ctgtcgccgc ggctccctgt
      121 cgcgcgccat gcaactcctc tgctggtggc aagtcctgct gtgggtgctg ggccttccgg
      181 cccacggcct ggaggttgca gaggacagtg gtcacccctg gcgggaggag cggcctgtcc
      241 ctgctctcca ggtaggagct gtgtatctgc atgaagagga ggttgctcag gaccatcggg
      301 accaggcaag agcggcggaa cccatggagg cctctctggg tccgcgcgga gatcccatgg
      361 tggtgctgtc agtggtccct ggggcagctg aggaccaacg gagccccgag gcccacgatg
      421 gcacctgcag tgcgcaggga gaggaggacc cgagctgtgg ccgagagaac ctcttcgggc
      481 tgcagggggc aggcggcttc caggatcggg aagaggagta ctatgctgag cctggcgtga
      541 ctgaggccga gcctgtagcc accgaggatg ccaacagcac tgacagcctc aagtccccca
      601 aggtgaattg tgaggagagg aatgtgactg ggctagaaaa cttcactctg aagattttaa
      661 atatgtccca ggacctcatg gatttcctaa acccaaatgg tagtgactgt acactggtcc
      721 tcttctacac cccgtggtgc cggttttctg ccagcctggc tcctcatttt aactccctgc
      781 cccgggcgtt tccaacactt ggcttcttgg ctctggatgc atctcagcac agcagccttt
      841 ctaccagatt tggcactgta gctgtcccta acattttgtt atttcaagga gctaaaccaa
      901 tggcaaggtt taaccataca gatcgcaccc tggaaacact gaaaatcttc attttcaatc
      961 agacgggtat agaagccaag aaaaatgtgg tggtaacgca ggctgaccag atgggccctc
     1021 tccccagcac tttgataaag actgtggatt ggttgctggt gttttccttg ttctttttaa
     1081 ttagtttcat tatgtatgct accatccgca ctgagagtat tcggtggctg attccaggac
     1141 aagaacagga acacgcagag taaagacaga actgaactgg aacaagaggg gtctcagccc
     1201 ctcctttgtg gacttagcat tacagtcgct aaatgtgtgg acttgcaacg gaaatcagat
     1261 tcaagaatca tgttcttgtt ggactactga aaagctgaaa agatttcata taaatgtgtt
     1321 tttcctatga caactagcag gtacaaaaat gtccactaga attgactgtt gttgcttttt
     1381 aatacttgaa cataatgaat ttcttttcta gtgtcgtcaa acaggaaagt gttgtctcag
     1441 aagaggagct aagatgggaa gtatgggcta ggacgggaag tgcaggtcta ctacaggacc
     1501 aggtgaaaaa taaagtcact gaaacaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
