LOCUS       NM_138628               4457 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus taxilin beta (Txlnb), mRNA.
ACCESSION   NM_138628
VERSION     NM_138628.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4457)
  AUTHORS   Sakane,H., Makiyama,T., Nogami,S., Horii,Y., Akasaki,K. and
            Shirataki,H.
  TITLE     beta-Taxilin participates in differentiation of C2C12 myoblasts
            into myotubes
  JOURNAL   Exp Cell Res 345 (2), 230-238 (2016)
   PUBMED   27231216
  REMARK    GeneRIF: These results demonstrate that beta-taxilin participates
            in myogenesis through suppressing the function of dysbindin to
            inhibit the differentiation of C2C12 myoblasts into myotubes.
REFERENCE   2  (bases 1 to 4457)
  AUTHORS   Benson,K.F. and Chada,K.
  TITLE     Molecular characterization of the mouse In(10)17Rk inversion and
            identification of a novel muscle-specific gene at the proximal
            breakpoint
  JOURNAL   Genetics 160 (1), 279-287 (2002)
   PUBMED   11805063
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK084639.1 and AK137442.1.
            
            On May 23, 2007 this sequence version replaced NM_138628.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF422245.1, BC141023.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849390
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-914               AK084639.1         2-915
            915-4457            AK137442.1         830-4372
FEATURES             Location/Qualifiers
     source          1..4457
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 7.24 cM"
     gene            1..4457
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /note="taxilin beta"
                     /db_xref="GeneID:378431"
                     /db_xref="MGI:MGI:2671945"
     exon            1..203
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     exon            204..649
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     CDS             217..2274
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /note="muscle-derived protein 77; muscle specific protein"
                     /codon_start=1
                     /product="beta-taxilin"
                     /protein_id="NP_619534.2"
                     /db_xref="CCDS:CCDS35851.1"
                     /db_xref="GeneID:378431"
                     /db_xref="MGI:MGI:2671945"
                     /translation="MEINHPDQLSVEHPTPPGDSSSLNQNGPGKQDGERCSTSGQAPE
                     QEGSLHPEKGAHDVAEELSRQLEDIISTYGSAASPRGKESTSETKEQPPNTEAPDNED
                     VDYEETTEEIDREPTAPEEPAAAKEPVSNKEQKLEKKILKGLGKEANLLMQNLNKLQA
                     PEEKLDFLFKKYTELLDEHRTEQKKLKLLLKQQAQTQREKDQLQSEHNRAVLARSKLE
                     SLCRELQRHNKTLKEETLQRAREEEEKRKEITSHFQTTLTDIQTQIEQQSERNMKLCQ
                     ENTELAEKLKSIIDQYELREEHLDKIFKHRELQQKLVDAKLEEAQELMQEAEERHRRE
                     KEYLLNQAAEWKLQAKVLKEQETVLQAQLTLYSGRFEEFQSTLTKSNEVFATFKQEMD
                     KTTKKMKKLEKDTATWKARFENCNKALLDMIEEKALRAKEYECFVMKIQRLENLCRAL
                     QEERKELYKKIREAKMSEKEDQVQRTSEEEPEPSVSENEEVDAEEANSFQKAVENLAT
                     AFTILHHPEFTPDQPTERQLAVNGPQSGSDVTHQHPETARLNHPSLPADSGSPRPPVG
                     AQAVAEGVCEATPAPTASCTPAEAELQSQGLPAENTPGPKPHKPEANTSGQAPLSPAQ
                     GSLSVVEAKYDISPSPESEGDSAVVPGCESREQPPPEVTDIPVGPSTGLPREPDACLN
                     GVD"
     exon            650..741
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     exon            742..912
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1107
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1227
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1302
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1395
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1491
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     exon            1492..4457
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2478..2483
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /note="hexamer: AATATA"
     polyA_site      2499
                     /gene="Txlnb"
                     /gene_synonym="2310001N14Rik; Mdp77"
                     /note="major polyA site"
ORIGIN      
        1 gccccctcct tttgtgggcg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
       61 tgtgtgtgca gtttctccct ccttgtaaga actcagccct gctgcctgtt cctgctgctg
      121 ctgctgctgc tgctgctgct cctcctctga ctctaccacc tctttcctct cttttctctt
      181 cctgcttagc tcccttcctt ctgaccccac tcccatatgg agattaatca tcctgatcag
      241 ctctcagtgg agcacccaac tcccccaggg gacagctcat cactcaatca aaacggcccg
      301 ggaaagcaag atggcgagcg gtgctcaacc tcaggccaag cgccagagca agagggaagc
      361 ctgcatcccg agaagggagc ccatgatgtc gcggaagagt tgagcaggca actggaagac
      421 atcataagca cgtatgggtc tgctgccagt ccccgaggga aggagagcac ctctgaaact
      481 aaggagcagc ccccaaacac agaggcacca gacaatgagg atgttgacta tgaagaaacc
      541 actgaagaga tagacagaga acccactgct cctgaagagc cagccgcagc caaagagcct
      601 gtcagcaata aagagcaaaa gctggaaaag aaaatcttaa aaggattagg taaagaagct
      661 aacttgctca tgcaaaacct gaacaagctg caagcacctg aagaaaagct tgatttttta
      721 ttcaagaagt atactgaatt gctggatgaa catcgcaccg agcaaaagaa actgaagctc
      781 ctactgaaac agcaggcgca gacccagaga gagaaggacc agttgcagag tgagcacaac
      841 agagccgtcc ttgctcgaag caaactcgag agtctgtgtc gggagctaca gaggcacaac
      901 aagacgctga aggaagaaac cctccaacgg gcgcgcgagg aagaagagaa gaggaaagag
      961 atcacaagtc actttcaaac taccctgaca gatatccaga ctcagatcga acaacagagt
     1021 gagcgcaata tgaagctctg ccaggagaac acagagcttg cagaaaaact gaaaagcatc
     1081 attgaccagt acgagctcag agaggagcat ctggacaaaa tattcaaaca tcgagaactg
     1141 cagcagaagc tggtggatgc gaaacttgaa gaggctcaag aactgatgca ggaggcagag
     1201 gagcggcaca gacgggagaa ggaatatttg ctgaaccagg cggcagagtg gaaacttcag
     1261 gccaaagtgc tgaaggagca ggagacggtg ctgcaggctc agctcactct ctactcagga
     1321 aggtttgagg agttccagag tacactgaca aaaagcaatg aagtgtttgc cactttcaag
     1381 caggaaatgg ataagacaac taagaaaatg aagaagctgg agaaggacac cgccacgtgg
     1441 aaagcccgat ttgagaattg taacaaagcc ctgttggaca tgatcgaaga gaaagccctg
     1501 cgagctaaag aatacgagtg tttcgtgatg aaaatccaaa ggctggagaa cctgtgtcgt
     1561 gctttacaag aggagagaaa ggaactctac aagaaaatca gagaagcaaa aatgtccgaa
     1621 aaggaagacc aggttcagcg cacctctgag gaagagccag agccaagcgt ctctgaaaat
     1681 gaagaggtgg acgcagagga agccaacagt tttcaaaaag ctgtggaaaa cctggccaca
     1741 gcttttacca tccttcatca tccagagttc accccagacc aaccaacgga aagacagctg
     1801 gcagtgaatg gtcctcaaag tggaagtgat gtcacccacc agcaccccga aacagcccgt
     1861 ttaaaccatc ccagccttcc cgctgattca gggagtcctc ggccccctgt aggtgctcag
     1921 gctgtggcgg agggcgtctg tgaggccaca cctgccccta cagcctcctg tacccctgca
     1981 gaggcagagc tacaaagtca gggtctccct gcagaaaata ccccgggtcc gaagccccat
     2041 aaaccagagg caaacacttc tggtcaggcc ccactgtccc cagcccaggg ctccctatct
     2101 gtagtagagg caaaatatga tatttcacca tctccagaga gtgagggaga ttctgctgtg
     2161 gtgcccggct gtgagtctag ggagcagccc ccaccagaag tcacagacat ccccgtaggc
     2221 ccttccactg gactccccag agagcccgat gcttgtctga atggagtaga ctaagccttg
     2281 ttgattcttc tggctgctca cctgactgca tcttcctcac agaagaaagt ctgtgaaaga
     2341 aacttctagg actaggaaga gttagagtca agacattttt aaagttgtac agaacacttc
     2401 cagtctttgc tgctgtttgc aatttataac taatatggaa attctctgtg atttggcagc
     2461 caaacacatc aatagcaaat atacattact ttcccattac attggtgcct taatccagtt
     2521 tgttagcagt aagattttgt atttaaggac tcccactata acaaataaat acactgaaat
     2581 attacattta tttccacaaa taacccaata agatctataa tggatatcca ggttccattt
     2641 aaatagcata atatacagtg tacttatgtg tatacacaat acacataaat acatttatgt
     2701 atacacatac acatgtattt tcatacgtgc atataaagtc atcacacaag tatattttgc
     2761 tcctaacaga tttttctcta ttgcaagata tgcttgtaaa aatttttcta tcttacttac
     2821 actctggact acagtagatt aaagctctat ggatcagaaa tagcacatgt gctacaatgc
     2881 ctggacacaa agaggaccac aagaggcttt taacagaaag gggaaaaaac acaaacaggt
     2941 gcttctgatc ttctcagcca acttcctccc aacttcccag catcacctcc tgggttgagg
     3001 cagccgcctc ctggctacct gtgagaaggt ggttggaaat agagaaagca cctaagtaag
     3061 atttgagagg ttgagtatcc tcagcttaga ggtctcagcc tctttgacta ctgatatctc
     3121 aagaaaacac tttttgttgt ctctgacatt gtctttatct caaagcatct attccttcca
     3181 aatttcctcc tttgcgtcaa tgtgtgtgcc tggcccacat ctcaattaat gttaagtaaa
     3241 atgtattttt ccaaaacgga aatacatacg agctctcaat aggagtaaca aggcttacaa
     3301 agctaacaca ttttctgctc taagaatttt tgaacaggca gaagtacaaa atttttaaaa
     3361 gggggggggg gcctcctact cataattcaa aaataacagg caaggactcc atagatgtca
     3421 aaagcaagaa gcacttggga ttacccaaac aagttttata ctctcattgt tcgcaaaaac
     3481 ctctaataac actggcagca taaaatgctc tgcctaggct caaagaaaac tgtactaaca
     3541 gaacagggag aggtgggaag gagggagaca gaaggtgcat aaagagagga cggtctaatc
     3601 taactctatg ttaagaagtt gaacacaggt agaaatgtgg ataaaggagg attcttgaaa
     3661 actcatccag gaaatcactc ttcagtggtg cacgtggctg cttgccaatg cacacgagga
     3721 gctgggaggc agtagccata tgttgaagga attataaaac tgtataaaat ttatttgaag
     3781 tagacagtaa gggaaagaac aaaaatacca tttggggaaa aaatcagggg aaaaagcatg
     3841 ccattatttg agaacccatg tgttttcaga ggctttgcat attataacca cacgggtatc
     3901 cagccaagtt caacaccact ggaaattaga cattcaatta actcaaagcc aaatattcac
     3961 tacactaatc ccttctctct gtttacagga gctgagcttc aaagaacaga gtaggatcat
     4021 cacagttagg tctcaatcca agagcttagg aagacaaaca ggcaggaggc actgacatcc
     4081 aataaattaa gtgttctcat atccaaagtt tattattttc atccaagagg gtttcacagc
     4141 aacatatcac tcacaactgt gtgtaccttt ggcacagttt cacagactac accttccctg
     4201 aaatctgtaa agctttaata tagactttgg gagaattatt ttaatagtaa aagaatgttt
     4261 tattatagtt ccttgtgttc aaacttggct gtactaatca taacaactca taagatctga
     4321 aagcagaaaa tatatctctt tttatgaagt tcatataact atttttagag atgccaagtc
     4381 tttctagaaa cactggaatt attgctttct aaatgtaata acataatgtt tataccaatt
     4441 aaaaaggcat ttcttcc
//
