LOCUS       NM_001013778            3315 bp    mRNA    linear   ROD 23-APR-2024
DEFINITION  Mus musculus trans-golgi network vesicle protein 23A (Tvp23a),
            transcript variant 1, mRNA.
ACCESSION   NM_001013778
VERSION     NM_001013778.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3315)
  AUTHORS   Griffin,E.N., Jucius,T., Sim,S.E., Harris,B.S., Heinz,S. and
            Ackerman,S.L.
  TITLE     RREB1 regulates neuronal proteostasis and the microtubule network
  JOURNAL   Sci Adv 10 (2), eadh3929 (2024)
   PUBMED   38198538
REFERENCE   2  (bases 1 to 3315)
  AUTHORS   Bussink,A.P., Speijer,D., Aerts,J.M. and Boot,R.G.
  TITLE     Evolution of mammalian chitinase(-like) members of family 18
            glycosyl hydrolases
  JOURNAL   Genetics 177 (2), 959-970 (2007)
   PUBMED   17720922
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122352.4.
            
            On Dec 20, 2017 this sequence version replaced NM_001013778.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC068110.1, SRR7345562.1474135.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164136
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-433               AC122352.4         42821-43253         c
            434-578             AC122352.4         24550-24694         c
            579-668             AC122352.4         23274-23363         c
            669-797             AC122352.4         22892-23020         c
            798-926             AC122352.4         21651-21779         c
            927-986             AC122352.4         20090-20149         c
            987-3315            AC122352.4         16448-18776         c
FEATURES             Location/Qualifiers
     source          1..3315
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 5.61 cM"
     gene            1..3315
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /note="trans-golgi network vesicle protein 23A"
                     /db_xref="GeneID:383103"
                     /db_xref="MGI:MGI:3665441"
     exon            1..433
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /inference="alignment:Splign:2.1.0"
     CDS             318..986
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /note="isoform 1 is encoded by transcript variant 1;
                     family with sequence similarity 18, member A"
                     /codon_start=1
                     /product="Golgi apparatus membrane protein TVP23 homolog A
                     isoform 1"
                     /protein_id="NP_001013800.1"
                     /db_xref="CCDS:CCDS27949.1"
                     /db_xref="GeneID:383103"
                     /db_xref="MGI:MGI:3665441"
                     /translation="MACHLSAPAVPQGLGDDTEDVSLDFGNEEELAFRKAKIRHPLAT
                     FFHLFFRVSAIVTYVCCDWFSKSFVGCFVTVLLLLSFDFWSVKNVTGRLMVGLRWWNQ
                     IDEDGKSHWIFEARKVSANHMAATEAEARIFWLGLIICPVIWIVFFFSTLFSLKLKWL
                     ALVIAGISLQAANLYGYILCKMGGDGDMRTVAASFLSQTVFQTDFPGDFEKPRLEGLD
                     IHRH"
     exon            434..578
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /inference="alignment:Splign:2.1.0"
     exon            579..668
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /inference="alignment:Splign:2.1.0"
     exon            669..797
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /inference="alignment:Splign:2.1.0"
     exon            798..926
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /inference="alignment:Splign:2.1.0"
     exon            927..986
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /inference="alignment:Splign:2.1.0"
     exon            987..3315
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3294..3299
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /note="hexamer: AATAAA"
     polyA_site      3315
                     /gene="Tvp23a"
                     /gene_synonym="Fam18a"
                     /note="major polyA site"
ORIGIN      
        1 atcgatcact agagctgagc taaggctggg agcatcccac aggcgggctc cctgctgggc
       61 atcctaaact ttgggcggtg aagggcagag ctggaacctg tgctatagtg tcaagtggta
      121 cccaggggga tgaagcaggt agggctgcag agatgctgca ttgggaggta gatgcactgg
      181 ccttgaaggc taagcccccg agcagtaagg agggtgggga aagcctaggg aactaaggga
      241 ataatgctgg gaggagcaca gagacatatc cagggagaga gggcgctcac gcccgaaggc
      301 ctcctgtgag ctctgggatg gcctgccatc tatctgctcc tgctgttccc cagggcctag
      361 gggatgatac tgaggatgtg tccctggact tcggtaatga agaggagctg gcctttagaa
      421 aggccaagat caggcacccc ctggctacct tcttccacct gttcttccga gtgagtgcca
      481 tcgtcaccta tgtgtgctgt gactggttca gcaagagctt tgtgggctgc tttgtcaccg
      541 tgctcctcct cctgtccttt gacttctggt ctgtgaagaa tgtaactgga agactcatgg
      601 tgggtcttcg atggtggaac cagatagacg aggatgggaa aagccactgg atatttgaag
      661 ccagaaaggt ctctgcaaac cacatggctg ccactgaggc agaggcacgc atcttctggc
      721 ttggtctcat catctgccca gtgatctgga ttgtgttctt cttcagtacc ttgttctcct
      781 tgaagctgaa gtggctggct cttgtgattg ctggcatttc cctccaagct gcgaacctct
      841 acggctacat cctctgtaag atgggaggcg acggtgatat gcgcacagtt gcagccagct
      901 ttctgtccca gacagtgttt cagacggact tcccaggtga cttcgagaag cccaggctgg
      961 aagggctgga catccaccgg cactaggctg ctgtggctgg tgaatctgga gcttcgacaa
     1021 aaaaagactg gcctttgtca cagctcttgc cttaaagaga cagaggaaag gagacccttg
     1081 taaaagcctt gctcttttgt gcctgctgct gtatggctgc ctgcggctcc ccattcaagg
     1141 acagcaaagg tggagagaca caacacatgc cccagttgtg tcccttcctc agcaatgatg
     1201 ttgctttgct gcggcaaagg cagattctag gcccaaagaa ctgctctgct gagtggtccc
     1261 aggagtctgc atgagagcca ctaacccgca gcccaggaaa atgagaatac aggagaggga
     1321 atcagaacat cgaggactaa gaaaggaaat gcagacgggg caagcttctg cagctctgag
     1381 gaaacacaca tgtaaatgtg gaatatatac tgcctcttag tgagcagaac ccttggcact
     1441 caccctgtcc tctgcctaca accctatcat gtccattatg gtccttccca gctgcactgt
     1501 ctctctgtct ctgtctctct cacacacaca cataaacagg cacacacatt caccattctg
     1561 aggaccatat gtaacccagg ggagaccagc tttgcctgtg aacctccctc aaggcccagt
     1621 ccccatgttg ttacccaagg ccccattcaa acacctcagt cccttcttcc ctgacaggag
     1681 aagggaagct cccacatttg ggtagtcatc tgcagctgaa agtagtctgc ctcaggctct
     1741 tccctctgag acctaggcac ctggcactgc tccacttcct gctcccgtca caggcatctg
     1801 cgactcaagc aagctcaact cttattgtgg ggaaagtgga atctacaggg cagaagagcc
     1861 cttgtctcct cacagcaaac caatacctgg atgagcctgg gacagagtta gttgcacacc
     1921 actccctcag ttctgaagac cattcagcgc acaattgtca gagcccagct caggagcaga
     1981 gtgaccaagg gccctgcagt cctagggaca cataactgga atttcatgga ggatatgagg
     2041 tgcctgcccc aggcctcact gcttctctcc tgtggctgca gcctctaagg agctctgtgg
     2101 gtccagttct gagccaccac tgctggtcct gcatccaagc ccccgggctg ctaagatggc
     2161 tgtgcacaca gcacaggccc ctcagaactc acctatgtgt ggatccagcg gcactttgcc
     2221 cagaagtgga atcctcagat cctggcacat ggcctctgca cccccagtcg tgggagggaa
     2281 gatctgagac tctttctgtg aggcagaaag agaaggaggc ttgattttgc ttctgcgtct
     2341 cagaacaact agtttttaga cattttgaaa cagtgccttg ttgcctgtga cactctgaag
     2401 cgtcttcgtc caggcagtag tagagggctt gatggagacc ctcccttccc aaaacagcag
     2461 gaaaagcaga aaccatccct gtcgtttcct cactgtgaca gtggtgtgct taggcctgcc
     2521 ttggggaccc tcaccttgca cttggggcag atgaaaccgc tcatgttttc taccacacca
     2581 atgatgggca gcttcacctt gtggcagaag ctgatctctt tccggacatc ctggagggcc
     2641 acctcctggc aaagttcaca gagcagttat ccctcattca gagggcacgg aaaggcacgt
     2701 gtggtccagg agatgctgta cagttgtcag agcgctcact cacctgaggg gtggtgagga
     2761 tcactgcccc atcaatgtgt gccgcagcca ggtactggac cactgagagg tgttcgtcag
     2821 acgtgccagg cggggtgtct acgatgaggt agtccacgtc tccccagtct acatcacgga
     2881 ggaactgctt gatcatacct agaagtgggc aaggctgagt gcgtgccttc tttctggcat
     2941 acatctccag cagcatcttt cattatgcat aagcatttgg cctacattct cagcctcagc
     3001 acagtgacag tgctgtcccc agggggcagg cggtgagatc tgtagacatg ctgggtggcc
     3061 atgatgaagt caggggtgct cctgtctatg tgtggcatag acatgtggtt ccaatagtca
     3121 tgtggcttaa gtgtcaatag ggagaaggtg cttgcccagc ggtgctatct gcatcatctt
     3181 aggcttcccc agaaaggggt tttcactcca cacttctctc cttgacacaa accagtcacg
     3241 tgatcacact acagatcact tcagtcttaa aagtagaaaa gctcacagta ggtaataaaa
     3301 tgtctacact gaaaa
//
