LOCUS       NM_026954               1364 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus tumor suppressor candidate 1 (Tusc1), mRNA.
ACCESSION   NM_026954 XM_914468
VERSION     NM_026954.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1364)
  AUTHORS   Shan,Z., Parker,T. and Wiest,J.S.
  TITLE     Identifying novel homozygous deletions by microsatellite analysis
            and characterization of tumor suppressor candidate 1 gene, TUSC1,
            on chromosome 9p in human lung cancer
  JOURNAL   Oncogene 23 (39), 6612-6620 (2004)
   PUBMED   15208665
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY546089.1.
            
            On Dec 7, 2005 this sequence version replaced XM_914468.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AY546089.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 43.25 cM"
     gene            1..1364
                     /gene="Tusc1"
                     /gene_synonym="2200001D17Rik; TSG-9"
                     /note="tumor suppressor candidate 1"
                     /db_xref="GeneID:69136"
                     /db_xref="MGI:MGI:2684283"
     exon            1..1364
                     /gene="Tusc1"
                     /gene_synonym="2200001D17Rik; TSG-9"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..709
                     /gene="Tusc1"
                     /gene_synonym="2200001D17Rik; TSG-9"
                     /note="tumour suppressor candidate 1"
                     /codon_start=1
                     /product="tumor suppressor candidate gene 1 protein
                     homolog"
                     /protein_id="NP_081230.1"
                     /db_xref="CCDS:CCDS18357.1"
                     /db_xref="GeneID:69136"
                     /db_xref="MGI:MGI:2684283"
                     /translation="MWRMRGGATRRGSCGGEGGGSRGESGRLGRAREGGGGGGGVGWR
                     GRAGGARRQLEERFADLAASHLEALRARDERDRQNARLREENARLRLENRRLRRENRS
                     LFRQALRLPGDSGEREAAVETLAPDEPATNRKARGHGREEEPGSPRALRARLEKLEVM
                     YRRALLQLHLEQQGARPPGAIEEPPLQETATGLCAHDPDVPRPWL"
ORIGIN      
        1 gcgaccgagc gcccagccag gccccaagtc cgcccgcgcc ccgcgcgcgg cccctcgggc
       61 cacggactgg cggcgcgacc agaccggacc gatgtggcgc atgcgtggtg gcgccacccg
      121 gcgcgggagc tgcggcgggg aaggcggcgg gagccgcggc gagtcgggcc gcctgggccg
      181 ggcccgtgag ggcggcggtg gcggtggcgg cgtgggctgg cgaggccgcg cgggcggggc
      241 ccggcgacag ctggaggagc gcttcgccga cctggcggcc agccacctgg aggccctgcg
      301 cgcgcgggac gagcgggacc ggcagaacgc gcggctgcgc gaggagaacg cccgcctgag
      361 gctggagaac cgtcggctca ggcgcgagaa ccgcagcctc ttccgccagg ctctgcggct
      421 gccgggcgac agcggcgagc gggaggccgc cgtcgagacc ctcgccccgg acgagcccgc
      481 caccaaccgc aaggcgagag gccatggccg tgaggaggag ccgggcagcc ccagggcgct
      541 gcgggcccgg ctagagaagc tggaggtcat gtaccgccga gcgctcctgc agctgcacct
      601 agagcagcag ggcgcgcgcc cgccgggagc catcgaggag ccaccgctcc aagaaactgc
      661 caccggcctg tgcgcccatg atccggacgt tccgaggccc tggctgtagt ccgagggcac
      721 ggagggaggt gggacctgcg cgcgccccgc ctccgtagta ctccgggctc cgcccctctc
      781 agcacgcgga agtttgaagt cctgagctcc tgaactccag ccccacccaa gggcacttcc
      841 aggcgccaaa tccgttggcc tgatggagaa agagaagcaa gagtttccca gttcccactt
      901 gtgcaaagca actgccaagt acactgctgg tgtgttgaga ggggtccaac aactctaaga
      961 cctgctttaa agcagcaaga actgggtgcc tggtcgcacc tcctaaattc ttgaagtttt
     1021 caaagtgttg tgaggaccag tttttttgcc acccctcccc ccccccccat ctttgatgct
     1081 ttgaaggatg aatagtgtat ttgattggtg atgcctgttc attctactgt ccaaaaactc
     1141 tgctcttttc tcttatacaa cccacctttt aagtgtgttt tgtaaattgc tgacttggat
     1201 agcccatgaa gtactacctt tttataaaga aaaaaatatt tataattgcc cgtcattcca
     1261 atccacatat gtttaatata ttctcgtgtg ttggcctcca gagatctttt tagagtatct
     1321 tctgacaggt gatgatttga gctgataaat aaactggtgc attg
//
