LOCUS       NM_001286007            3158 bp    mRNA    linear   ROD 24-SEP-2024
DEFINITION  Mus musculus tubulin, gamma complex component 2 (Tubgcp2),
            transcript variant 1, mRNA.
ACCESSION   NM_001286007
VERSION     NM_001286007.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3158)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3158)
  AUTHORS   Camblor-Perujo,S., Ozer Yildiz,E., Kupper,H., Overhoff,M.,
            Rastogi,S., Bazzi,H. and Kononenko,N.L.
  TITLE     The AP-2 complex interacts with gamma-TuRC and regulates the
            proliferative capacity of neural progenitors
  JOURNAL   Life Sci Alliance 7 (2), e202302029 (2023)
   PUBMED   38086550
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3158)
  AUTHORS   Camargo Ortega,G., Falk,S., Johansson,P.A., Peyre,E., Broix,L.,
            Sahu,S.K., Hirst,W., Schlichthaerle,T., De Juan Romero,C.,
            Draganova,K., Vinopal,S., Chinnappa,K., Gavranovic,A., Karakaya,T.,
            Steininger,T., Merl-Pham,J., Feederle,R., Shao,W., Shi,S.H.,
            Hauck,S.M., Jungmann,R., Bradke,F., Borrell,V., Geerlof,A.,
            Reber,S., Tiwari,V.K., Huttner,W.B., Wilsch-Brauninger,M.,
            Nguyen,L. and Gotz,M.
  TITLE     The centrosome protein AKNA regulates neurogenesis via microtubule
            organization
  JOURNAL   Nature 567 (7746), 113-117 (2019)
   PUBMED   30787442
REFERENCE   4  (bases 1 to 3158)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   5  (bases 1 to 3158)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY234488.1, AK146771.1, AC107822.18 and AK006233.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a). Variants 1 and 2
            both encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK158060.1, SRR9219382.52238.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-328               BY234488.1         5-332
            329-1976            AK146771.1         251-1898
            1977-1977           AC107822.18        209625-209625       c
            1978-3111           AK146771.1         1900-3033
            3112-3158           AK006233.1         1141-1187
FEATURES             Location/Qualifiers
     source          1..3158
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 84.98 cM"
     gene            1..3158
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /note="tubulin, gamma complex component 2"
                     /db_xref="GeneID:74237"
                     /db_xref="MGI:MGI:1921487"
     exon            1..328
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            329..514
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             365..3082
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /note="isoform a is encoded by transcript variant 1;
                     gamma-tubulin complex component 2; GCP-2; tubulin, gamma
                     complex associated protein 2"
                     /codon_start=1
                     /product="gamma-tubulin complex component 2 isoform a"
                     /protein_id="NP_001272936.1"
                     /db_xref="CCDS:CCDS21960.1"
                     /db_xref="GeneID:74237"
                     /db_xref="MGI:MGI:1921487"
                     /translation="MSEFRIHHDVNELLSLLRIHGGDGAEVYIDLLQKNRTPYVTTTV
                     SAHSAKVKIAEFSRTPEDFLKKYDELKSKNTRNLDPLVYLLSKLTEDKETLQFLQQNA
                     KERAELAASAATSNTTSFSIPVAASKMSTQELEELRKQLGSVSTGSTLQQSLELTRKM
                     LRDKQNKKNSGQPLPVFPAWVYERPTLAGDFLIGSGLSSDTVLPIGTLPLASQESAVV
                     EDLLYVLVGVDGRYITAQPLAGRQNRTFLVDPNLDLSIRELVNRILPVAASYSTVTRF
                     IEEKSSFEYGQVNHALAAAMRTLVKEYLILVTQLEQLHRQGLLSLQKLWFYIQPAMRT
                     IDILASLATSVDKGECVGGSTLSLLHDRSFNYTGDSQAQELCLYLTKAASAPYFEILE
                     KWIYRGIIHDPYSEFMVEEHELRKEKIQEDYNDKYWDQRYTVLPQQIPSFLQKVAGKI
                     LSTGKYLNVVRECGHDVTCPVAKEIIYTLKERAYVEQIEKAFNYASKVLLDFLMEEKE
                     LVAHLRSIKRYFLMDQGDFFVHFMDLTEEELRKPVEDIILTRLEALLELALRMSTANT
                     DPFKDDLKIELMPHDLITQLLRVLAIETKQEKAMTHADPTELTLSGLEAFSFDYMVKW
                     PLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWISNKTAKQHALHSAKWFAGAFTL
                     RQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTSFLDNCLKDCMLT
                     NPELLKVFSKLMSVCVMFTNCMQKFTQSMKLDSELGRLTLDQGSVQGPPTETERIEDR
                     PRKELTRKHLSEHVDAPQLASGFEATINNFDKNFSAHLLDLLARLSVYSTSDCEHGMA
                     SVISRLDFNGFYAERLERLSAERSQKAAPQVPVPRGPSAPAPRVAIPAQ"
     exon            515..643
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            644..820
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            821..980
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1188
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1388
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1578
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1579..1724
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1725..1905
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1906..2086
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2259
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2260..2388
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2389..2509
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2510..2653
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2654..2782
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2783..2946
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2947..3158
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      3113
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
                     /note="major polyA site"
     polyA_site      3158
                     /gene="Tubgcp2"
                     /gene_synonym="1700022B05Rik"
ORIGIN      
        1 gcgacagtct tgcttctagg cccctccctg tggggctcag gacatcttcc gcccgggttg
       61 tcacgcacct cgaagaattc gtgatcccgc gggaagcgca cggcacgcgg cgcgaatcgg
      121 aagggtgcct ccccagccgc agggttcctc tccacgggca gcggttcggc tgcccccggc
      181 tccccggcca ggcgggaata tagtgcaggg ggaagcaaca tcaccacggc cgccgcggcc
      241 cttcggccac cgtcggaggg gtggtgacgg acgtgacgtc tactaacttc ctgtggcgac
      301 cctgcggggc gggacgcgac gcgcggagga aaacttggtt atgttggtgt ctcagagcta
      361 aactatgagc gaatttcgga ttcaccatga tgtcaatgag ctgctcagcc tgctccgcat
      421 ccatggcggg gatggggctg aggtctacat tgacctgctg cagaagaacc ggacgccgta
      481 tgtcacaacc acagtctctg cccacagtgc caaggtcaaa attgcagaat tttctcgaac
      541 tcctgaggac tttttaaaga aatatgatga actgaaatct aaaaatacaa ggaaccttga
      601 cccactggtg tacctgttat caaaactcac agaagacaaa gagacacttc agtttttgca
      661 acagaatgca aaggaaagag ctgagcttgc agctagtgct gcaactagca acaccaccag
      721 cttcagcatc cctgttgcag cctctaagat gtccacacaa gagctagagg aactgaggaa
      781 gcagcttggc agtgtatcca caggctccac actgcagcag tctctggaac ttacaagaaa
      841 gatgcttcga gacaaacaga acaaaaaaaa ttcaggccag cccctccctg tcttcccagc
      901 atgggtgtat gagagaccaa cattggctgg agatttcctg attggctcgg gcttgagctc
      961 agacacagtt ttgcctatag gtacattgcc cttggcctcc caggagtcag ctgtggtgga
     1021 agatctgctc tatgtgcttg tgggtgtgga tggcaggtat atcactgctc agcctttggc
     1081 tgggaggcag aaccgtacct tccttgtcga ccccaacctg gacctgtcca tccgggagct
     1141 agtaaacaga atcctccctg tggccgccag ctactctact gtgaccaggt tcattgagga
     1201 gaagtcttca tttgaatatg ggcaggtgaa ccatgccctg gctgctgcca tgagaaccct
     1261 agtaaaggaa tacctgattc tggtcacaca gctggaacag ctgcacaggc agggcctcct
     1321 ctcactgcag aagctctggt tctacatcca gccagccatg cgcaccatcg acatccttgc
     1381 ctcccttgcc acctcagtgg ataaaggcga gtgtgtgggc gggtcgacac tgagccttct
     1441 tcatgatagg agcttcaact acaccgggga cagccaggcg caggagctgt gcctctatct
     1501 gaccaaggca gccagtgcac cttacttcga gatcctggag aagtggatct ataggggcat
     1561 cattcatgac ccatacagtg agttcatggt ggaggaacac gagctgcgga aggagaagat
     1621 ccaggaggac tacaacgaca agtactggga ccagcgctac actgtgctgc cgcagcagat
     1681 cccatccttc ctgcagaagg tagcaggcaa gatcctcagc acaggaaaat acctaaatgt
     1741 ggtcagagag tgtggtcatg atgtcacctg tcccgtagcc aaagaaatca tctataccct
     1801 taaagagcgg gcatatgtgg agcagataga gaaagcgttc aattatgcca gcaaagtgct
     1861 gctggacttc ctcatggagg agaaggagct ggtggcccac ctgaggtcca tcaagcgcta
     1921 cttcctgatg gaccaggggg acttcttcgt gcatttcatg gacctgactg aggaggagct
     1981 caggaagcca gtggaggaca tcatactcac acgcctggag gccctgttgg agctggccct
     2041 gcgaatgagc actgccaaca ctgacccctt caaagacgac ctcaagattg aactgatgcc
     2101 tcacgaccta atcactcagc ttttgcgggt tctggccatc gagaccaagc aggaaaaggc
     2161 aatgacccat gctgacccca cggagctcac actgagtggt ctggaggcct tctcctttga
     2221 ctacatggtc aaatggcccc tgtcactgat tattaacagg aaggcactca cccgctacca
     2281 gatgctcttc cgacacatgt tctactgcaa gcacgtggag cggcagctct gcagtgtctg
     2341 gatcagcaac aagacggcca agcagcatgc actgcactcc gccaagtggt ttgctggtgc
     2401 tttcactctg cggcagcgaa tgctcaactt tgtccagaat attcagtact acatgatgtt
     2461 tgaagtgatg gaaccgacct ggcacatcct tgagaaaaac ctgaaatctg cctccaacat
     2521 tgacgatgtc cttggccacc acacaagctt ccttgacaac tgcctgaagg actgcatgct
     2581 gaccaaccct gagctgctga aggttttctc caagctcatg tccgtatgcg tcatgtttac
     2641 caactgtatg cagaaattta cacagagtat gaaactggac agtgagctag gccgtctgac
     2701 actggatcag ggtagtgtgc aggggccacc cacagagact gaacggattg aggatcgccc
     2761 ccggaaggag cttaccagga agcatctgtc tgagcatgtg gatgctcctc agctggcctc
     2821 tggtttcgag gccaccatca acaactttga caaaaacttc tctgcccatc ttcttgattt
     2881 gctggcccga ctaagtgtct acagcaccag tgactgcgaa catggcatgg ccagtgtcat
     2941 ctccagacta gatttcaatg gtttctatgc tgaacgcctg gaacgtctgt ctgcagaaag
     3001 gagtcagaag gctgcccccc aagtgcctgt cccacgggga ccctcagcac cagcacccag
     3061 ggtggccatt cctgcgcaat gagctcactt gttaaatatc attatttctg gaacatggct
     3121 gttgtgcatt attactgctt aaatatggtt tgagtttc
//
