LOCUS       NM_011654               1747 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus tubulin, alpha 1B (Tuba1b), mRNA.
ACCESSION   NM_011654
VERSION     NM_011654.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1747)
  AUTHORS   Ebeid,M., Kishimoto,I., Roy,P., Zaidi,M.A.A., Cheng,A.G. and
            Huh,S.H.
  TITLE     beta-Catenin transcriptional activity is required for establishment
            of inner pillar cell identity during cochlear development
  JOURNAL   PLoS Genet 19 (8), e1010925 (2023)
   PUBMED   37639482
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1747)
  AUTHORS   Leca,I., Phillips,A.W., Ushakova,L., Cushion,T.D. and Keays,D.A.
  TITLE     Codon modification of Tuba1a alters mRNA levels and causes a severe
            neurodevelopmental phenotype in mice
  JOURNAL   Sci Rep 13 (1), 1215 (2023)
   PUBMED   36681692
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1747)
  AUTHORS   Jarred,E.G., Qu,Z., Tsai,T., Oberin,R., Petautschnig,S.,
            Bildsoe,H., Pederson,S., Zhang,Q.H., Stringer,J.M., Carroll,J.,
            Gardner,D.K., Van den Buuse,M., Sims,N.A., Gibson,W.T.,
            Adelson,D.L. and Western,P.S.
  TITLE     Transient Polycomb activity represses developmental genes in
            growing oocytes
  JOURNAL   Clin Epigenetics 14 (1), 183 (2022)
   PUBMED   36544159
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1747)
  AUTHORS   Liu,H., He,L., Cheng,Q., Luo,W., Zhao,T. and Yang,D.
  TITLE     Validation of superior reference genes in mouse submandibular
            glands under developmental and functional regeneration states
  JOURNAL   Int J Mol Med 50 (5) (2022)
   PUBMED   36069228
REFERENCE   5  (bases 1 to 1747)
  AUTHORS   Mattebo,A., Sen,T., Jassinskaja,M., Pimkova,K., Prieto
            Gonzalez-Albo,I., Alattar,A.G., Ramakrishnan,R., Lang,S., Jaras,M.,
            Hansson,J., Soneji,S., Singbrant,S., van den Akker,E. and
            Flygare,J.
  TITLE     Yippee like 4 (Ypel4) is essential for normal mouse red blood cell
            membrane integrity
  JOURNAL   Sci Rep 11 (1), 15898 (2021)
   PUBMED   34354145
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1747)
  AUTHORS   Chu,C.C. and Paul,W.E.
  TITLE     Expressed genes in interleukin-4 treated B cells identified by cDNA
            representational difference analysis
  JOURNAL   Mol Immunol 35 (8), 487-502 (1998)
   PUBMED   9798653
REFERENCE   7  (bases 1 to 1747)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
REFERENCE   8  (bases 1 to 1747)
  AUTHORS   Gao,Y., Vainberg,I.E., Chow,R.L. and Cowan,N.J.
  TITLE     Two cofactors and cytoplasmic chaperonin are required for the
            folding of alpha- and beta-tubulin
  JOURNAL   Mol Cell Biol 13 (4), 2478-2485 (1993)
   PUBMED   8096061
REFERENCE   9  (bases 1 to 1747)
  AUTHORS   Villasante,A., Wang,D., Dobner,P., Dolph,P., Lewis,S.A. and
            Cowan,N.J.
  TITLE     Six mouse alpha-tubulin mRNAs encode five distinct isotypes:
            testis-specific expression of two sister genes
  JOURNAL   Mol Cell Biol 6 (7), 2409-2419 (1986)
   PUBMED   3785200
REFERENCE   10 (bases 1 to 1747)
  AUTHORS   Lewis,S.A., Lee,M.G. and Cowan,N.J.
  TITLE     Five mouse tubulin isotypes and their regulated expression during
            development
  JOURNAL   J Cell Biol 101 (3), 852-861 (1985)
   PUBMED   3839797
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC108394.1.
            
            On Aug 6, 2006 this sequence version replaced NM_011654.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC108394.1, BC083120.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1747
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 55.21 cM"
     gene            1..1747
                     /gene="Tuba1b"
                     /gene_synonym="Tuba2"
                     /note="tubulin, alpha 1B"
                     /db_xref="GeneID:22143"
                     /db_xref="MGI:MGI:107804"
     exon            1..58
                     /gene="Tuba1b"
                     /gene_synonym="Tuba2"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..1411
                     /gene="Tuba1b"
                     /gene_synonym="Tuba2"
                     /note="tubulin, alpha 2; alpha-tubulin 2; tubulin alpha-2
                     chain; alpha-tubulin isotype M-alpha-2"
                     /codon_start=1
                     /product="tubulin alpha-1B chain"
                     /protein_id="NP_035784.1"
                     /db_xref="CCDS:CCDS37195.1"
                     /db_xref="GeneID:22143"
                     /db_xref="MGI:MGI:107804"
                     /translation="MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGG
                     GDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANN
                     YARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
                     YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLD
                     IERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVI
                     SAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAT
                     IKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD
                     HKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEE
                     Y"
     exon            59..281
                     /gene="Tuba1b"
                     /gene_synonym="Tuba2"
                     /inference="alignment:Splign:2.1.0"
     exon            282..430
                     /gene="Tuba1b"
                     /gene_synonym="Tuba2"
                     /inference="alignment:Splign:2.1.0"
     exon            431..1564
                     /gene="Tuba1b"
                     /gene_synonym="Tuba2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgagacccgg tgtctgcttc tatctctcac cctcgccttc taacccgttg ctatcatgcg
       61 tgagtgcatc tccatccacg ttggccaggc tggtgtccag atcggcaatg cctgctggga
      121 gctctactgc ctggaacatg gcatccagcc tgatggccag atgccaagtg acaagaccat
      181 tgggggagga gatgactcct tcaacacctt cttcagtgag acaggagctg gcaagcatgt
      241 gccccgggca gtgttcgtag acctggaacc cacggtcatc gatgaagttc gcaccggcac
      301 ctaccgccag ctcttccatc ctgagcagct catcacaggc aaggaggatg ctgccaataa
      361 ctatgcccgt ggccactaca ccattggcaa ggagatcatt gaccttgtcc tggacaggat
      421 tcgcaagctg gctgaccagt gcacaggtct ccagggcttc ttggttttcc acagctttgg
      481 tgggggaact ggctctggct tcacctccct gctgatggag cggctctctg tggattacgg
      541 aaagaagtcc aagctggagt tctccattta cccagccccc caggtttcca ctgctgtggt
      601 tgagccctac aattccatcc tcaccaccca caccaccctg gagcactctg attgtgcctt
      661 catggtagac aatgaggcca tctatgacat ctgtcgtaga aacctcgaca ttgagcgccc
      721 aacctacacc aaccttaacc gccttattag ccagattgtg tcttccatca ctgcttccct
      781 cagatttgat ggggccctga atgttgatct gacagaattc cagaccaacc tggtacccta
      841 ccctcgcatc cacttccctc tggccactta tgcccctgtc atctctgctg agaaagccta
      901 ccatgagcag ctttctgtag cagagatcac caatgcctgc tttgagccag ccaaccagat
      961 ggtgaaatgt gaccctcgcc atggtaaata catggcttgc tgcctgctat accgtggtga
     1021 tgtggttccc aaagatgtca atgctgccat tgccaccatc aagaccaagc gcagcatcca
     1081 gtttgtagac tggtgcccca ctggcttcaa ggttggcatt aattaccagc ctcccactgt
     1141 ggtacccggt ggtgacctgg ccaaggtgca gagagctgtg tgcatgctga gcaacaccac
     1201 agccattgct gaggcctggg ctcgcctaga tcacaagttt gatctgatgt atgccaagcg
     1261 tgcctttgtg cactggtatg tgggtgaggg catggaggag ggtgagttct ctgaggcccg
     1321 tgaggacatg gctgccctag agaaggatta tgaggaggtt ggtgtggatt ctgtggaagg
     1381 cgagggggag gaagaaggag aggagtacta agtccattcc ttgagccccc tgtgtcgtca
     1441 aactgctcca gtattagttg caggcactga tgcttctgtg ctgtttccat tctgtgatca
     1501 tgtcttctcc atgttgtacc tcttaagttt tccatgatgt ctcaaagtaa aagctttaag
     1561 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1621 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1681 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1741 aaaaaaa
//
