LOCUS       NM_181734               4548 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus tocopherol (alpha) transfer protein-like (Ttpal),
            transcript variant 2, mRNA.
ACCESSION   NM_181734
VERSION     NM_181734.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4548)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK039450.1 and BC052389.1.
            
            On Aug 22, 2006 this sequence version replaced NM_181734.2.
            
            Transcript Variant: This variant (2) uses an alternate splice site
            in the 5' UTR compared to variant 1. Variants 1 and 2 encode the
            same isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052389.1, AK156641.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2181              AK039450.1         2-2182
            2182-4548           BC052389.1         2140-4506
FEATURES             Location/Qualifiers
     source          1..4548
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 84.37 cM"
     gene            1..4548
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /note="tocopherol (alpha) transfer protein-like"
                     /db_xref="GeneID:76080"
                     /db_xref="MGI:MGI:1923330"
     exon            1..101
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            102..564
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..1148
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /note="isoform 1 is encoded by transcript variant 2;
                     alpha-tocopherol transfer protein-like"
                     /codon_start=1
                     /product="alpha-tocopherol transfer protein-like isoform
                     1"
                     /protein_id="NP_859423.2"
                     /db_xref="CCDS:CCDS38317.1"
                     /db_xref="GeneID:76080"
                     /db_xref="MGI:MGI:1923330"
                     /translation="MSEESDSLRTSPSVASLSENELPLPPPDPPGYVCSLTEDLVTKA
                     REELQEKPEWRLRDVQALRDMVRKEYPYLSTSLDDAFLLRFLRARKFDYDRALQLLVN
                     YHGCRRSWPEVFSNLRPSALKDVLNSGFLTVLPHTDPRGCHVLCIRPDRWIPSNYPIT
                     ENIRAVYLTLEKLIQSEETQVNGIVILADYKGVSLSKASHFGPFIAKKVIGILQDGFP
                     IRIKAVHIVNEPRIFKGIFAIIKPFLKEKIANRFFLHGSDLNSLHTNLPRNILPKEYG
                     GTAGELDTASWNAVLLASEEDFVKEFCQPMPACDNLLGQPLLPEGLISDAQCDDSMRA
                     MKSQLYSCY"
     exon            565..758
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            759..869
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            870..4520
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4498..4503
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4520
                     /gene="Ttpal"
                     /gene_synonym="3110080A02Rik; 5830472M02Rik"
                     /note="major polyA site"
ORIGIN      
        1 gagggccggg ccggccggcc ggggagtgcg ggtctgttct gcgcgcgctg ccagccgagg
       61 ctcctgccgc cgtgacccgc gctccgcccg ccgccgggct gggaccctga tagctaatgt
      121 cagaagaaag tgactctctg agaaccagcc cctctgtggc ctcactctcc gaaaatgagc
      181 tgccactgcc tccaccggac cctcccggct acgtgtgctc cctgacagaa gacttggtca
      241 ccaaagccag ggaagagctg caggagaagc ccgagtggag gctgcgggat gtgcaggccc
      301 tccgagacat ggtgcggaag gagtacccat acctgagcac gtcgctggac gatgccttcc
      361 tgttgcgctt tctgagggcc cgaaagtttg attatgaccg ggccctgcag ctgctggtca
      421 actaccacgg ctgcaggcgg agctggccag aggtcttcag caacctgagg ccgtcagccc
      481 tgaaagacgt tctcaactct ggattcctta cagtgctgcc ccacacggac cccaggggct
      541 gccatgtcct ctgcatccga ccagacagat ggataccaag caactaccca attaccgaga
      601 acatccgagc cgtatacttg acattagaaa aactcattca gtccgaggag acccaggtga
      661 acgggattgt tatccttgcc gactacaagg gagtgagctt atcaaaagca tctcattttg
      721 ggccttttat agccaaaaag gtgattggca tccttcagga tggcttcccc attcggataa
      781 aagcagttca catagtgaac gaacctcgga tatttaaggg cattttcgcc atcataaaac
      841 catttctgaa ggagaaaatt gctaacaggt tcttcctcca tgggtctgac ctgaactctc
      901 tccacacaaa cctgccaagg aatatcctcc ccaaggagta tgggggcaca gctggggagc
      961 tggacactgc ctcctggaac gccgtgctgc tggcctcaga ggaggatttt gtgaaagagt
     1021 tctgccagcc catgcctgcc tgcgacaacc tcctgggcca gcccctgcta cctgaggggc
     1081 tgatctcaga tgcgcagtgt gatgactcca tgcgagccat gaagtcccag ctctactcct
     1141 gctattagcc ctctttcggg agagtaccgt gtgtgattcc ttccttcctt ccttagaaat
     1201 gcacaggctg agatgccagg acctccgtct tgctccatcc ctctgcaaca gcatggagct
     1261 gcctgcagag atttaaggca cgcccatcac aggcagacct ttgactgagt tattccaggg
     1321 aagacatgga aattgccctg gtgtactctt aagtttgcag ctgttactct ggaagctgta
     1381 tctgtttctt atgcatcttg gaaagaacta aggtcaaagt cactctgaag tgaccaggag
     1441 aagacaactt gactgatcac aactctgaaa caatcaccaa tccttagagg tggccacacg
     1501 taagactttt gagtctcttt cccataaacc ctaggtgttg acctcttgct catcagcaaa
     1561 gttcaaggtt caggccccag ttgtcattgt tgggcctggg aagcactaac tgagtggtag
     1621 aaaccccagg cccaggtagt acttaagatc aaatttggaa gccaaaggct tcaaagcatc
     1681 cctgggagtc cagggttaaa tcttgcaata gaaacttttc ccaaccccat aaagccttag
     1741 ctctggttct ccatggaatc atgtaggtca gcataaaata ctggattcta ggactgtgtg
     1801 gctaaaagca tttggaccag gagtcaggtc gtatgactga caagacacgg gcttcagctt
     1861 gtcatctctc agtgaggcta catggaatga gggtctttgt ggctgctgaa gttgttaggc
     1921 ttctgcttgg gaagacatta cctagaggtg gttggatctt tttgttttgt tttgttgtag
     1981 tatgaataca gccttatgta aaggaacagc accatctggc cctcccttta aagaaactag
     2041 tatgttcctg ggagttggtg gagaccaact gcctttgcag aataatgggt aaacttgaaa
     2101 gggatggctt tggtgaggcc gaccagatct catacaaact ccttccacac tggagacatt
     2161 catactatat tagaaacagc cacagtaatt gccaggtttg ggctgttttt gtccctggaa
     2221 acatacagga gcaggctatt gctggttcac ctgggggccc tgccctctca gacacactgg
     2281 agtctcgtat gggaggacca cttggactga atgtcagctc tgtgtttggg tattttagac
     2341 acctgacaag gttttagcct taactcaagc actgagtgag gtgatttatc tcctggcttt
     2401 tgacttgttc cctttgtatt cactatgtat tatagtgtca agtactgttg gttgtacatc
     2461 tcctggactt aagcaggcat tgcatacagc ttacacacag tgcttggaga tcaaaggtca
     2521 gtcggttgtt actaagctgt tccaccctta acagcatttc ccaaaatgtc tacagaagct
     2581 ctttatggaa acttacctca ataatgtcaa ttctatggga cattcttttc actttagatg
     2641 ctaatcgttg atcttttagg tcctggctaa gctttagggc caatataccc ctcttgactg
     2701 cccattgaga ccatttgctg ctgagtttct gctatttggt ttagctcctg gcctcctaga
     2761 cacctgaaaa gacccatgat ggccccctgc agccttgatg ggagagtctt attagaagct
     2821 ttcttaggtg gttcagaagg aaaaaacaaa gggaaaacct cagtcccact gggttccctg
     2881 aatttaaatt gtgtcacctg actagttctc ctgacttaac aaagggacaa ccaggctctt
     2941 ggggagaaat ctcagggcag aaatgttacc tgtttgccag gcctttctgg ctaggccaag
     3001 agggagccat tccatcaagc ctctaaggag gctggctctg ctatgttctc actaatgctt
     3061 gtggactcta gagatccatc ttggcacctc agctttgaag caggctgtga gaccaggacc
     3121 tcctggtgca aaataaagca actcttatgt tgagcagcag gggagacgaa ggcctcacct
     3181 gcgggaagca cactggtgga gccagcaagt gagcaagaac ctgggagtat ctgactttgg
     3241 ggtaaagtgc tagacgcttc acagacagct ggaaatccac ctttcctaaa ttcaaggtca
     3301 tgtggtatat tggaagagaa agggatagaa cattaacacc ctgagtgctg gacaggggct
     3361 tgtatgctaa actctgaatc ctgttcctga ccagactctg gccgtaagga cgctatactt
     3421 tgcctggtgc tgaaatgtcc tagtgtaggg atatgggaat ttccttcaag cccgctacag
     3481 atttctaggc aattcagctt cctattaatg tacgttttct gccttcatgc aggaatacag
     3541 ataaaaccta cagaaacagt aaaagtgctg gcttcaggca caggtggatt tgtactgttc
     3601 acatttcatc ccaggtttgt aagcatcaca ggttatgggg cagcttcttc agagttggag
     3661 gactggggtc atttcctctg aatactttaa atggctttat tacctagcag gcaatttgat
     3721 gtgatgtcat ctcactcttg agatcattca tggaacttgc ttttcagttg ggcagcaaca
     3781 gctagctact ctggtgttgt ggtggtatta taatacctca tcaaggattt tcttatgaca
     3841 cctcctttag gaaggaaaag gctaactcag ttgatagaag tatagttgtg ctgtggtcat
     3901 gttaggcaga aacaccagac acatgagctg ttgggagaca tcttggtgag gctcagtact
     3961 gcagtctgtt cactttgtaa acctgctttc tgctctcctg actcagaaat gttcagcttc
     4021 aaaatgcaag aagcaccatc aaatgctgct tctcagcggg aacttgctcc acaggaaggt
     4081 ccagtggaat ttgcagctgg aatcacattt actggtttgt gaccaaattt actggttttc
     4141 aatcttttcc catcaggcag ttactggtag ccgctttgga ttcttgtgga tgtgcctcag
     4201 cttcttggca cattacaaag ggcccaacag gtaaaatact tgaaacttct cagtggccaa
     4261 gacctcagat accctctctg atgggtggga actgggctat tttcctgacc agtctaggcc
     4321 accattttag tccccagtca catcccttac ttcaaactga aattcagttt ggctttgagt
     4381 ataggcacat atgatggatt cacctacttc agtgttttga ccaaaagttt atttttctag
     4441 tgcatttttc taagtggtga aaatatgtaa ttttagtatg catgactggg tctccaaaat
     4501 aaaaacccct ggaaagcgga aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
