LOCUS       NM_028639               4600 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus tetratricopeptide repeat domain 7 (Ttc7), transcript
            variant 2, mRNA.
ACCESSION   NM_028639
VERSION     NM_028639.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4600)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4600)
  AUTHORS   Gajardo,T., Bernard,M., Lo,M., Turck,E., Leveau,C., El-Daher,M.T.,
            Deslys,A., Panikulam,P., Menche,C., Kurowska,M., Le Lay,G.,
            Barbier,L., Moshous,D., Neven,B., Farin,H.F., Fischer,A.,
            Menasche,G., de Saint Basile,G., Vargas,P. and Sepulveda,F.E.
  TITLE     Actin dynamics regulation by TTC7A/PI4KIIIalpha limits DNA damage
            and cell death under confinement
  JOURNAL   J Allergy Clin Immunol 152 (4), 949-960 (2023)
   PUBMED   37390900
  REMARK    GeneRIF: Actin dynamics regulation by TTC7A/PI4KIIIalpha limits DNA
            damage and cell death under confinement.
REFERENCE   3  (bases 1 to 4600)
  AUTHORS   Leveau,C., Gajardo,T., El-Daher,M.T., Cagnard,N., Fischer,A., de
            Saint Basile,G. and Sepulveda,F.E.
  TITLE     Ttc7a regulates hematopoietic stem cell functions while controlling
            the stress-induced response
  JOURNAL   Haematologica 105 (1), 59-70 (2020)
   PUBMED   31004027
  REMARK    GeneRIF: Ttc7a regulates hematopoietic stem cell functions while
            controlling the stress-induced response.
REFERENCE   4  (bases 1 to 4600)
  AUTHORS   Nuesch,U., Mauracher,A.A., Opitz,L., Volkmer,B., Michalak-Micka,K.,
            Kamarashev,J., Hartwig,T., Reichmann,E., Becher,B., Vavassori,S.
            and Pachlopnik Schmid,J.
  TITLE     Epithelial proliferation in inflammatory skin disease is regulated
            by tetratricopeptide repeat domain 7 (Ttc7) in fibroblasts and
            lymphocytes
  JOURNAL   J Allergy Clin Immunol 143 (1), 292-304 (2019)
   PUBMED   29775636
  REMARK    GeneRIF: Epithelial proliferation in inflammatory skin disease is
            regulated by tetratricopeptide repeat domain 7 (Ttc7) in
            fibroblasts and lymphocytes.
REFERENCE   5  (bases 1 to 4600)
  AUTHORS   Pan,J., Mor,G., Ju,W., Zhong,J., Luo,X., Aldo,P.B., Zhong,M.,
            Yu,Y., Jenkins,E.C., Brown,W.T. and Zhong,N.
  TITLE     Viral Infection-Induced Differential Expression of LncRNAs
            Associated with Collagen in Mouse Placentas and Amniotic Sacs
  JOURNAL   Am J Reprod Immunol 74 (3), 237-257 (2015)
   PUBMED   26073538
REFERENCE   6  (bases 1 to 4600)
  AUTHORS   White,R.A., McNulty,S.G., Roman,S., Garg,U., Wirtz,E.,
            Kohlbrecher,D., Nsumu,N.N., Pinson,D., Gaedigk,R., Blackmore,K.,
            Copple,A., Rasul,S., Watanabe,M. and Shimizu,K.
  TITLE     Chromosomal localization, hematologic characterization, and iron
            metabolism of the hereditary erythroblastic anemia (hea) mutant
            mouse
  JOURNAL   Blood 104 (5), 1511-1518 (2004)
   PUBMED   15155459
REFERENCE   7  (bases 1 to 4600)
  AUTHORS   Sundberg,J.P., France,M., Boggess,D., Sundberg,B.A., Jenson,A.B.,
            Beamer,W.G. and Shultz,L.D.
  TITLE     Development and progression of psoriasiform dermatitis and systemic
            lesions in the flaky skin (fsn) mouse mutant
  JOURNAL   Pathobiology 65 (5), 271-286 (1997)
   PUBMED   9459497
REFERENCE   8  (bases 1 to 4600)
  AUTHORS   Beamer,W.G., Pelsue,S.C., Shultz,L.D., Sundberg,J.P. and
            Barker,J.E.
  TITLE     The flaky skin (fsn) mutation in mice: map location and description
            of the anemia
  JOURNAL   Blood 86 (8), 3220-3226 (1995)
   PUBMED   7579418
REFERENCE   9  (bases 1 to 4600)
  AUTHORS   Pelsue,S.C., Schweitzer,P.A., Beamer,W.G. and Shultz,L.D.
  TITLE     Mapping of the flaky skin (fsn) mutation on distal mouse chromosome
            17
  JOURNAL   Mamm Genome 6 (10), 758 (1995)
   PUBMED   8563181
  REMARK    Erratum:[Mamm Genome 1996 Jan;7(1):92]
REFERENCE   10 (bases 1 to 4600)
  AUTHORS   Sundberg,J.P., Kenty,G.A., Beamer,W.G. and Adkison,D.L.
  TITLE     Forestomach papillomas in flaky skin and steel-Dickie mutant mice
  JOURNAL   J Vet Diagn Invest 4 (3), 312-317 (1992)
   PUBMED   1325193
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084383.1.
            
            On Apr 8, 2022 this sequence version replaced NM_028639.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK050263.1, AK080284.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-511               AC084383.1         31322-31832
            512-675             AC084383.1         38611-38774
            676-844             AC084383.1         41233-41401
            845-975             AC084383.1         55351-55481
            976-1091            AC084383.1         57151-57266
            1092-1170           AC084383.1         69825-69903
            1171-1328           AC084383.1         70860-71017
            1329-1392           AC084383.1         71546-71609
            1393-1530           AC084383.1         77745-77882
            1531-1614           AC084383.1         78447-78530
            1615-1719           AC084383.1         82689-82793
            1720-1837           AC084383.1         88313-88430
            1838-1895           AC084383.1         89310-89367
            1896-1968           AC084383.1         90489-90561
            1969-2129           AC084383.1         94963-95123
            2130-2246           AC084383.1         107536-107652
            2247-2341           AC084383.1         110271-110365
            2342-2476           AC084383.1         111878-112012
            2477-2679           AC084383.1         118881-119083
            2680-4600           AC084383.1         128271-130191
FEATURES             Location/Qualifiers
     source          1..4600
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 57.12 cM"
     gene            1..4600
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /note="tetratricopeptide repeat domain 7"
                     /db_xref="GeneID:225049"
                     /db_xref="MGI:MGI:1920999"
     exon            1..511
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     CDS             325..2901
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /note="isoform 2 is encoded by transcript variant 2; TPR
                     repeat protein 7A; tetratricopeptide repeat protein 7A"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 7A isoform 2"
                     /protein_id="NP_082915.1"
                     /db_xref="CCDS:CCDS29016.1"
                     /db_xref="GeneID:225049"
                     /db_xref="MGI:MGI:1920999"
                     /translation="MAAKGAHGTHLKVESEVERCRAEGQWDRMFELARHLQMLGISGG
                     GSSNRRNSPSGRFTTLDTDDFVKLLLAEALLEQCLKDNHDKIKNSIPLLEKTDHRLNE
                     AKDHLSSLLNNGKLPPQYMCEAMLILGKLHYVEGSYRDAVSMYARAGIDDISVENKPL
                     YQMRLLSEAFVIKGLSLERLPNSVASHIRLTEREEEVVACFERASWVAQVFLQELEKT
                     SNNSTSRHLKGSLSPDYELSYFLEAALQSAYVKNLKKGNIVKGMRELREILRTVETKA
                     TQNFKVVAAKHLAGVLLHSLSEDCYWSPLSHPLPEFMNKEENSFVTQTLRKPHLYEGD
                     NLYCPKDNIEEALLLLLISESMATRDVVLSRAPEQAEDRKVSLQNASAIYDLLSITLG
                     RRGQYVMLSECLERAMKCAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSDPT
                     VPLMAAKVCIGSLHWLEEAEHFATVVIGLGEEAGESLPKGYLALGLTYSLQATDATLK
                     SKQDELHRKALQTLERARELAPDDPQIIFYVALQLALVRQISSAMERLQEALTMCRDD
                     ANALHLLALLFSAQKYYQHALDVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTC
                     RQMLRLWQTLYNFSQLGGLEKDGSFEGLTVKKQNGIHLTLPDAHDADSGSRRASSIAA
                     SRLEEAMSELTLTTSVLKQGPMQLWTTLEQIWLQAAELFMEQRQLKEAGFCIQEAAGL
                     FPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVRIMHSLGLMLSQLGHKSLA
                     QKVLRDAVERQSTFHEAWQGLGEVLQDQGQNEAAVDCFLTALELEASSPVLPFSIIAR
                     EL"
     exon            512..675
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            676..844
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            845..975
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1091
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1170
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1328
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1392
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1530
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..1614
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1719
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1720..1837
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..1895
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1896..1968
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2129
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2246
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            2247..2341
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            2342..2476
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            2477..2679
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     exon            2680..4600
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4568..4573
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /note="hexamer: AATAAA"
     polyA_site      4600
                     /gene="Ttc7"
                     /gene_synonym="1110035E02Rik; 1700007L07Rik; fsn; hea;
                     Ttc7a"
                     /note="major polyA site"
ORIGIN      
        1 gtggcagcag ctgctgcaca ggaggagaca gcagcgtcag gagctgctgc agcagcggcg
       61 gaggctgctt ctggacgcct tggggtcgcg cagccgcagc cccagtccag aggctccagg
      121 cggtgcggtg ggcgctgccg ccgccgctgc tgctgctgct gctgcgggcc ccttgccgtt
      181 acccgggccc cctctgccac ccgggccccg gatgccgtct gcactcccgt caagcctgct
      241 ggagagtgct ccccagcctg gacgccgccc ccggcctggt ctccactcct ccgccgcacc
      301 tcccatgaca gctcctgctc gaagatggct gcgaagggcg cgcacggcac ccacctgaag
      361 gtggagagcg aggtggagcg ctgccgcgcc gagggccagt gggaccgcat gttcgagctg
      421 gcccggcatc tgcagatgct gggcatttcc ggcggcggca gtagcaaccg gcgaaacagc
      481 ccgagcggca ggttcaccac tctggacacc gatgactttg tgaaattgct gctagcggag
      541 gccctcctgg agcagtgtct gaaggataac cacgacaaaa taaaaaactc catccctttg
      601 ctggagaaga ctgatcacag gctgaatgaa gccaaggacc acctgagcag cctcctcaac
      661 aatgggaaac tgccgccaca gtacatgtgt gaagccatgc tgatcctggg caagctgcac
      721 tatgtggagg gctcgtaccg ggacgctgtc agcatgtatg cacgggctgg gatcgatgac
      781 atatccgtgg agaacaagcc cctgtatcag atgcggttgc tgtcggaggc ctttgtcatc
      841 aaaggcctct ccctggaacg cctgcccaac tccgtcgcct cccacatccg cctgactgag
      901 cgggaggagg aagtggttgc ctgttttgag agggcctctt gggtggctca ggtattcctg
      961 caggagctgg agaagacctc aaacaacagc acatcaagac acctgaaagg cagcctctcg
     1021 cctgactatg agctgtccta cttcctggaa gctgccctcc agagcgcata tgtgaagaac
     1081 ctgaaaaagg ggaatattgt gaaaggcatg agggagctcc gggagattct gaggactgtg
     1141 gagaccaaag cgacacagaa cttcaaagtg gtggccgcca agcacctggc aggggtcctg
     1201 ctgcactccc tgagcgagga ctgttactgg agccccctgt cccacccttt gcctgagttc
     1261 atgaacaagg aggagaactc ttttgtcact cagactcttc ggaaacctca cctctacgaa
     1321 ggggacaacc tctactgccc caaagacaac atagaggagg ccctcttgct gctgctcatc
     1381 agtgagtcca tggcaactcg ggacgtggta ctgagtcggg caccagagca ggcggaggac
     1441 cggaaagtga gcctgcagaa tgcttcagcc atttatgacc tcctgagcat cacgctgggc
     1501 cggcgaggcc agtatgtcat gctatcagag tgcctagagc gagccatgaa gtgtgctttt
     1561 ggagaatttc acctttggta ccaagtggcc ctctccatgg tggcttgtgg gaagtcagcc
     1621 tacgccgtgt cgctgctgcg tgagtgcatg aagttgcagc cctcggaccc cacggtaccc
     1681 ctgatggctg ccaaggtctg cattgggtcc ctgcattggc tagaagaggc agaacacttt
     1741 gccacggtag taattggtct tggagaggaa gctggagagt ccctgcctaa aggctacctg
     1801 gccctgggcc tcacctacag cctgcaggcc actgatgcca ccctgaagtc caagcaagat
     1861 gagcttcacc gcaaggcact gcagacactg gagagagccc gggaactggc acccgatgat
     1921 ccccaaatta tcttctatgt cgccctgcag ctggccctcg tccgacagat ctccagcgcc
     1981 atggagcgtc ttcaggaggc cctgacgatg tgcagggatg atgccaatgc cctccacttg
     2041 ctagcgctgc tcttctctgc ccagaagtat taccagcacg ccctggacgt catcaatatg
     2101 gccatcaccg agcatcctga aaatttcaac ctgatgttca ccaaggtgaa gctggagcag
     2161 gtactgaaag gcccggagga agccctcgtg acttgcagac aaatgctgcg gctgtggcag
     2221 accctctaca acttctctca gctggggggc ctggaaaagg atggcagctt tgaaggcctc
     2281 acagtgaaga aacagaacgg tatccacctg actctgccag atgcccatga tgcagactct
     2341 ggctctaggc gggcgtcgtc tatcgcagcc tcaaggctgg aagaggccat gtcggaatta
     2401 accttaacaa cctcagtcct gaagcagggc cccatgcagc tctggaccac actggagcag
     2461 atctggctcc aggccgctga gctgttcatg gagcagagac aactcaagga agcgggtttc
     2521 tgcatccagg aggctgctgg cctcttcccc acctctcact cggtactcta catgcgaggc
     2581 cgactagctg aggtgaaggg cagcttcgaa gaggccaagc agctgtacaa ggaggctctc
     2641 accgtaaacc cggacggcgt gcgcatcatg cacagcctgg gtctgatgct gagtcagctg
     2701 ggccacaaga gcctggccca gaaggtgctg cgggatgctg tggagagaca gagcaccttc
     2761 cacgaagcgt ggcagggcct gggggaggtg ctgcaggacc aaggccagaa cgaagcggcc
     2821 gtggactgct tcctcacagc cctggagctg gaggccagca gccctgtgct gcccttctcc
     2881 atcattgcca gagagctgtg agcctctgca gctgcagctg gcagccatat actgcctgcc
     2941 aggggcgggg cgggggcagc agacacaggc agggggcagg gaagggcgtg tgtccagatg
     3001 tggggcctca gggaatagat gacaagtgag cacttccact ggcttccatg ccacttctcc
     3061 tcccacactc cacaccctgc aggcccagct gggcctaagc tcctgactga agctgggggg
     3121 acaagatttg catccaaggc aaacgcctcg cctcccccag agactgccgg ttgctgggca
     3181 cctcttagat aaaaggtgtg tctgggagcc aagccccttc cttggcttcc cccaccaccc
     3241 cgggtttcct ggtttgggat gaaccaatct tgagtttgtg taccacagag atgagtgcct
     3301 tgggagacaa actggcttga atctcagcga cttcacagag ctgtgagcag acgtgccgga
     3361 gagccccgga tacatttccc catccgatct cagggcagtg caaagcttga agccttgccc
     3421 aggacagcca cagcttgagg tcccagatac aaagagggac agtgggctcc tgggctcttg
     3481 tcagcctgaa ttggccctgt tgatgcctgg tgtttccttt atggggaggt tgcctagagg
     3541 ctacatgtga tttctctgta ccaccaagtg ccttttggac tcatgtcggc caggcctcta
     3601 aacaccgtcc cccgtcttcc attttcactc actgtcatct ccctggagac acgccccagt
     3661 cagtagactc cgtgggccct gagccggtgg cctccaggat acgccttgga atacaaaaca
     3721 gggttctgac gtagccattc ctggtacctt gagtacacag tccctcaagt ctttggaccc
     3781 gcccacttgg gtgaatgaca tccaagtgac catttatagg cctcagccca gtacacctca
     3841 tcacccactg cccagttttc atcttaggct ttgctgagtg accccaaagc cccagcttgg
     3901 ccttttgtgc tcccctgcct agattcccac agcggccatg cttgaggaac ctgacagcct
     3961 gcctcacctt tctgtgcccg cgtgctctct gtcaggtcgc tgggcagctg tccctccctg
     4021 gctcgtcagc catgcactct ggttttgaaa ctttccctca ggaagccatt ccccaaggcc
     4081 tagcagagag ttccttctgt ctcccctact ctgggtagag ctccctcggg ttcaccttgc
     4141 gcttgtgtta gaatgtgtca ggggtcaccg tgctgaccac agtggccttg cggagaaagc
     4201 cgttggagtc tggctccgtg gtggactgat gtaccctgct tgtcccctcg tgtctccaga
     4261 gagctggtgc ctcctggcca cagccacagg ccaaagggag gctattcagt ccttggttga
     4321 agggtctcta tgtgtatatg tgtatgtgtg tgcatatata tatatatgta tatgtatata
     4381 tatgctagag atctatattt ttatggaatt ctgttagagt aaaaaagaga aaagcagata
     4441 ctattggctg gccttggagg tcaatcttgg cagtgggaaa gacagcaaat gtgtggactg
     4501 actaagcgtc ctctctttgg aggccctagg aggcaggccc agtgcctgac agtgactttg
     4561 gaaattgaat aaaagaccct tggaggggga caagactgtc
//
