LOCUS       NM_001145948            2344 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus tetratricopeptide repeat domain 39A (Ttc39a),
            transcript variant 1, mRNA.
ACCESSION   NM_001145948
VERSION     NM_001145948.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2344)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2344)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   3  (bases 1 to 2344)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL669905.14.
            
            On Jan 3, 2023 this sequence version replaced NM_001145948.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK076641.1, AK076772.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849378, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-111               AL669905.14        75009-75119
            112-216             AL669905.14        75359-75463
            217-348             AL669905.14        80665-80796
            349-425             AL669905.14        81818-81894
            426-493             AL669905.14        82247-82314
            494-558             AL669905.14        85673-85737
            559-658             AL669905.14        87503-87602
            659-724             AL669905.14        88259-88324
            725-833             AL669905.14        90228-90336
            834-901             AL669905.14        90763-90830
            902-961             AL669905.14        90911-90970
            962-1123            AL669905.14        92361-92522
            1124-1215           AL669905.14        98121-98212
            1216-1336           AL669905.14        99894-100014
            1337-1448           AL669905.14        101599-101710
            1449-1563           AL669905.14        102069-102183
            1564-1680           AL669905.14        102880-102996
            1681-2344           AL669905.14        103454-104117
FEATURES             Location/Qualifiers
     source          1..2344
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 51.29 cM"
     gene            1..2344
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /note="tetratricopeptide repeat domain 39A"
                     /db_xref="GeneID:230603"
                     /db_xref="MGI:MGI:2444350"
     exon            1..111
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..1804
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     tetratricopeptide repeat protein 39A; TPR repeat protein
                     39A"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 39A isoform 1"
                     /protein_id="NP_001139420.1"
                     /db_xref="CCDS:CCDS51260.1"
                     /db_xref="GeneID:230603"
                     /db_xref="MGI:MGI:2444350"
                     /translation="MGQKGHKDSLYDCKGSPVSSLHEALDQCMTALDLFLTNQFSEAL
                     SYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQSLCQRHRRKSSMT
                     DSFSNLVHRPTIDQFTEEEIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSY
                     QTYKELDSLVQSSQYSKGESHRHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGN
                     KDYGLLQLEEGATGHSFRAVLCVMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRY
                     PKGAIFLFFAGRIEAIKGNIDAAVRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQW
                     KMAYFYADLLSKENSWSKATYIYMKAAYLSMFGKEDYKPFGDNEVELFRAVPGLKLKI
                     AGKSLPTEKFAIRKSRRYLSPNPISLPIPALEMMYIWNGYAVIGKQPTLTDGMLEVIT
                     KAEEMLAMGPENEYSADDDCLVKLLKGLCLKYLGRIQEAEENFRSISANEKKIKYDHY
                     LIPNALLELALLFMEQGRNEEAIKLLESAKQNYKNYSMESRTHFRIQAATLQARSSLE
                     DGNRSLVSSVSL"
     exon            112..216
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            217..348
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            349..425
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            426..493
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            494..558
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            559..658
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            659..724
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            725..833
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            834..901
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            902..961
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1123
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1215
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1336
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1337..1448
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1563
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1564..1680
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..2344
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2315..2320
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2344
                     /gene="Ttc39a"
                     /gene_synonym="4922503N01Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtaagaact tggagaagaa atacccagag aggaacaagt ggtccctcag tgggacagca
       61 aagcctaatg ggtcagaagg gccacaagga ctccctttat gattgtaaag ggtctcctgt
      121 gagcagcctc catgaggccc tggaccagtg catgacagcc ctggacctct tccttaccaa
      181 ccagttctca gaagcactca gctacctcaa acccagaacc aaggagagca tgtatcactc
      241 cctgacgtat gccaccatcc tggagatgca ggccatgatg accttcgacc cccaggacat
      301 cctgcttgct ggcaacatga tgaaagaagc gcagtcgctg tgtcagaggc atcgaaggaa
      361 gtcttctatg acggactcat tcagcaacct ggtgcaccgt cctaccattg accagttcac
      421 agaagaggaa atccatgcag aggtctgtta tgcagaatgc ctactacaga gagcggccct
      481 gaccttcctg caggacgaga acatggtgag cttcatcaag ggcggcatca aagtgcggaa
      541 cagctaccag acttacaagg aactggatag cctcgtccag tcctcgcaat actctaaggg
      601 agagagccac agacactttg aaggaggggt gaagcttggc gtaggagcct tcaacctgac
      661 gctgtccatg cttcccacca ggattctgag gctgctggag tttgttgggt tttcaggaaa
      721 caaggactat gggctgctgc agctggagga gggcgcaacc ggacacagct tccgtgcagt
      781 gctgtgcgtc atgctgttgc tgtgttatca caccttcctc accttcgtgc tcggtactgg
      841 gaatgtcaac atcgaggagg cagagaagct gctgaagccc tacctgaacc gataccccaa
      901 gggcgccatc ttcctgttct ttgctgggcg gattgaagct atcaaaggaa atattgatgc
      961 tgctgtccgg cggtttgagg agtgctgcga ggcccagcag cactggaagc agtttcacca
     1021 catgtgctac tgggagctga tgtggtgctt tacctacaag ggccagtgga aaatggccta
     1081 cttctacgcc gacctgctga gcaaggagaa ctcctggtcc aaggccacct acatctacat
     1141 gaaggctgcc tacctcagca tgtttgggaa ggaagactac aagccattcg gggacaatga
     1201 agtggagtta ttcagggccg tgccaggctt gaagctcaag attgctggga aatctctacc
     1261 cacagagaag tttgctatcc ggaagtccag gcgctacctc tcccccaacc ccatctcctt
     1321 gccgatccct gctctggaaa tgatgtacat ctggaatggc tatgctgtga ttgggaagca
     1381 gccgacactc acggatggga tgctggaggt catcaccaag gctgaagaga tgctggcaat
     1441 gggcccagag aatgagtact cagcagatga cgactgcttg gttaaattgc tgaaaggcct
     1501 gtgtctgaaa tacctgggcc gaatccagga ggcagaggag aatttcagga gcatttctgc
     1561 caatgaaaag aagattaaat atgaccatta cttgattcca aatgccctac tggaactggc
     1621 cctgctattt atggagcaag gcagaaatga ggaggccatc aaactcttag agtctgcaaa
     1681 gcaaaactac aagaactact ccatggagtc aaggacacat tttcgaatcc aggcagccac
     1741 actccaggcc agatcttccc tagaagatgg caacagatct ctagtctcgt cagtgtcctt
     1801 gtagctttct gcagcactct tgggctgcac gatgaacaga cagctagctg gacagagcac
     1861 ctggaaacat ttctaaagat cacctcccct gccctgccct tccttggggt ccacctggtg
     1921 ctccagtagg attgcacaag aatatctgtg cagaagcaaa gacagcattt ttaccagtgt
     1981 ggccaaagcc ttcacacata cgggtacttg ttttacactg tgatgtttaa gagaatgtat
     2041 gaacagttta catttcttta gaaatacatc gatgggatta taattggtgt ttaaaaaacc
     2101 aaaccaaaca aactaccccc cccctccaaa caaacaaaag caacccgact gcctggaaag
     2161 ctgtttagct cctgacctgg aagttctcta catgctatta aaggccacac tgcttctcag
     2221 acctcagctt ttgaggacag gggttcctag catctgagtc attgcaaatt ccaggacagc
     2281 cacagctacg cagtgagaca ctgggtccaa acaaaataaa gcaaattaag ttgctaacat
     2341 ttaa
//
