LOCUS       NM_138951                789 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus tetratricopeptide repeat domain 36 (Ttc36), mRNA.
ACCESSION   NM_138951
VERSION     NM_138951.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Xie,Y., Lv,X., Ni,D., Liu,J., Hu,Y., Liu,Y., Liu,Y., Liu,R.,
            Zhao,H., Lu,Z. and Zhou,Q.
  TITLE     HPD degradation regulated by the TTC36-STK33-PELI1 signaling axis
            induces tyrosinemia and neurological damage
  JOURNAL   Nat Commun 10 (1), 4266 (2019)
   PUBMED   31537781
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  AUTHORS   Zhou,Y., He,Q., Chen,J., Liu,Y., Mao,Z., Lyu,Z., Ni,D., Long,Y.,
            Ju,P., Liu,J., Gu,Y. and Zhou,Q.
  TITLE     The expression patterns of Tetratricopeptide repeat domain 36
            (Ttc36)
  JOURNAL   Gene Expr Patterns 22 (2), 37-45 (2016)
   PUBMED   27826126
  REMARK    GeneRIF: Collectively, on the basis of the expression pattern,
            Ttc36 is specifically expressed in proximal distal tubules
REFERENCE   3  (bases 1 to 789)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   4  (bases 1 to 789)
  AUTHORS   Liu,Y., Lv,X., Tan,R., Liu,T., Chen,T., Li,M., Liu,Y., Nie,F.,
            Wang,X., Zhou,P., Chen,M. and Zhou,Q.
  TITLE     A modified TALEN-based strategy for rapidly and efficiently
            generating knockout mice for kidney development studies
  JOURNAL   PLoS One 9 (1), e84893 (2014)
   PUBMED   24416307
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 789)
  AUTHORS   Thiagarajan,R.D., Georgas,K.M., Rumballe,B.A., Lesieur,E.,
            Chiu,H.S., Taylor,D., Tang,D.T., Grimmond,S.M. and Little,M.H.
  TITLE     Identification of anchor genes during kidney development defines
            ontological relationships, molecular subcompartments and regulatory
            pathways
  JOURNAL   PLoS One 6 (2), e17286 (2011)
   PUBMED   21386911
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 789)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC024432.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC024432.1, BI099686.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849385, SAMN00849386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="FVB/N"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 24.84 cM"
     gene            1..789
                     /gene="Ttc36"
                     /note="tetratricopeptide repeat domain 36"
                     /db_xref="GeneID:192653"
                     /db_xref="MGI:MGI:2384760"
     exon            1..241
                     /gene="Ttc36"
                     /inference="alignment:Splign:2.1.0"
     CDS             133..693
                     /gene="Ttc36"
                     /note="TPR repeat protein 36"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 36"
                     /protein_id="NP_620401.1"
                     /db_xref="CCDS:CCDS23121.1"
                     /db_xref="GeneID:192653"
                     /db_xref="MGI:MGI:2384760"
                     /translation="MGTPNDQAVLQAIFNPDTPFGDVVGLDLEEAEEGDEDGVFPQAQ
                     LEHSKALELQGVRAAEAGDLHTALEKFGQAISLLPDRASAYNNRAQARRLQGDVAGAL
                     EDLERAVTLSGGRGRAARQSFVQSGLLARFQGRDDDARRDFEKAARLGSPFARRQLVL
                     LNPYAALCNRMLADMMGQLRAPSNGR"
     exon            242..430
                     /gene="Ttc36"
                     /inference="alignment:Splign:2.1.0"
     exon            431..764
                     /gene="Ttc36"
                     /inference="alignment:Splign:2.1.0"
     regulatory      744..749
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ttc36"
                     /note="hexamer: AATAAA"
     polyA_site      764
                     /gene="Ttc36"
                     /note="major polyA site"
ORIGIN      
        1 aggcacacct ctgtacctga ggcggtcccc aaacagaacc tcctccgttc acagcatctg
       61 ccagctggag gctctaccct gtccccacca tcttccttca cccactgagt taccacttgg
      121 gccctaggag ccatggggac tccaaatgat caggcagtgt tgcaggccat cttcaaccct
      181 gataccccct ttggagatgt tgttggattg gacctggaag aagcagagga gggagatgaa
      241 gatggagttt tccctcaagc acagttggag cactccaagg ccctggagtt gcagggagtg
      301 agggcggcag aagctggaga cctccacaca gcactggaga agtttggcca agccattagc
      361 ctgctacctg acagagcctc tgcctacaac aaccgagccc aagcccggcg gctccagggg
      421 gatgtagcag gcgccctgga ggacttggag cgcgcggtga cattgagcgg cggccggggt
      481 cgcgccgccc gccagagctt cgtgcagagc gggctactgg cgagatttca gggccgggac
      541 gacgacgccc gcagggactt cgagaaggct gcgcgactgg gcagcccgtt cgcacggcgc
      601 cagctagtgc tgctcaaccc gtacgccgcg ctgtgcaacc gcatgctggc cgacatgatg
      661 gggcagctgc gcgcgcccag caacgggcgc tgagcgtggc cggccgaatg atggagaggg
      721 ggaccctgac ccaaccagga cccaataaaa cttccgggac tctcaaaaaa aaaaaaaaaa
      781 aaaaaaaaa
//
