LOCUS       NP_690030                847 aa            linear   ROD 28-APR-2025
DEFINITION  tetratricopeptide repeat protein 27 [Mus musculus].
ACCESSION   NP_690030
VERSION     NP_690030.3
DBSOURCE    REFSEQ: accession NM_152817.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 847)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK030942.1, AK049324.1 and AI118251.1.
            
            On Jan 9, 2008 this sequence version replaced NP_690030.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK012131.1, AK030942.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..847
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 45.64 cM"
     Protein         1..847
                     /product="tetratricopeptide repeat protein 27"
                     /note="TPR repeat protein 27"
                     /calculated_mol_wt=96300
     Region          457..490
                     /region_name="TPR 1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8CD92.2)"
     Region          496..529
                     /region_name="TPR 2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8CD92.2)"
     Region          505..>678
                     /region_name="TPR"
                     /note="Tetratricopeptide (TPR) repeat [General function
                     prediction only]; COG0457"
                     /db_xref="CDD:440225"
     Region          531..564
                     /region_name="TPR 3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8CD92.2)"
     Region          531..559
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Site            order(532,535..536,539..540,542,566,569..570,573..574,
                     576..577,600,603..604,607..608,611)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          564..594
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          565..598
                     /region_name="TPR 4"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8CD92.2)"
     Region          568..837
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Region          599..627
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          600..632
                     /region_name="TPR 5"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8CD92.2)"
     Region          633..666
                     /region_name="TPR 6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8CD92.2)"
     Region          633..661
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     CDS             1..847
                     /gene="Ttc27"
                     /gene_synonym="2610511O17Rik"
                     /coded_by="NM_152817.4:163..2706"
                     /db_xref="CCDS:CCDS28972.1"
                     /db_xref="GeneID:74196"
                     /db_xref="MGI:MGI:1921446"
ORIGIN      
        1 mpgmmwtpel allrgfstea erlvwkqegi cgsdigvfle lllegsyeal ffhsttqtil
       61 nstmmaeeki dsylekqivn fldcstdlee ierqqlvfll gvsslqlfvq snwtgplvdl
      121 hpqdflpsgl leqfsevkgl daiimgllil dgesvyslts kpillliari ilvnirhklt
      181 alqslpwwtl ryvnihqqll eerspqlfal akncidqvmk qenlfegdsg rllaiqfhle
      241 cahvflyyye ykeakdqfst akdiskleid ltgalgkrtr fqenyvaqli vdvrrkeavp
      301 fscefspapt pqeclaknle lnddtvlnei kladserfqm pdlcaeelav vlgvctnfqk
      361 nnpvhkltee ellaftscll sqpkfwaiqm salilrtkle rgstrrvera mrqtqaladq
      421 fedkatsvle rlkifyccqv pphwavqrql agllfelgct ssalqifekl emwedvvich
      481 eragrhgkae eilrqelekk etpglycllg dvlqdhscyd kawelsrhrs araqrskall
      541 hlrnkefrec vecfersvki npmqlgvwfs lgcaylaled yggsakafqr cvtlepdnae
      601 awnnlstsyi rlkqkvkafr tlqealkcny ehwqiwenyi ltstdvgefg eaikayhrll
      661 dlrdkykdiq vlkilvqavv ndmtdrsgav asslkgklqe lfgritsrvt ndgevwrlya
      721 qvhgngqsek pdendkafqc lskaykcdtq sscwekdata fkevvqraig lahvamkcae
      781 sksipqeavq tlssvrlnlr gllskakqnf tdvvsgevsg elaseiaavn aleaelqdls
      841 nqlrnry
//
