LOCUS       NM_001168475            2231 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus tetratricopeptide repeat domain 23 (Ttc23), transcript
            variant 2, mRNA.
ACCESSION   NM_001168475
VERSION     NM_001168475.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2231)
  AUTHORS   Ikegami,K., Saigoh,K., Fujioka,A., Nagano,M., Kitajima,K., Sato,C.,
            Masubuchi,S., Kusunoki,S. and Shigeyoshi,Y.
  TITLE     Effect of expression alteration in flanking genes on phenotypes of
            St8sia2-deficient mice
  JOURNAL   Sci Rep 9 (1), 13634 (2019)
   PUBMED   31541165
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2231)
  AUTHORS   Breslow,D.K., Hoogendoorn,S., Kopp,A.R., Morgens,D.W., Vu,B.K.,
            Kennedy,M.C., Han,K., Li,A., Hess,G.T., Bassik,M.C., Chen,J.K. and
            Nachury,M.V.
  TITLE     A CRISPR-based screen for Hedgehog signaling provides insights into
            ciliary function and ciliopathies
  JOURNAL   Nat Genet 50 (3), 460-471 (2018)
   PUBMED   29459677
REFERENCE   3  (bases 1 to 2231)
  AUTHORS   Alvarez-Dominguez,J.R., Zhang,X. and Hu,W.
  TITLE     Widespread and dynamic translational control of red blood cell
            development
  JOURNAL   Blood 129 (5), 619-629 (2017)
   PUBMED   27899360
REFERENCE   4  (bases 1 to 2231)
  AUTHORS   Alvarez-Dominguez,J.R., Hu,W., Yuan,B., Shi,J., Park,S.S.,
            Gromatzky,A.A., van Oudenaarden,A. and Lodish,H.F.
  TITLE     Global discovery of erythroid long noncoding RNAs reveals novel
            regulators of red cell maturation
  JOURNAL   Blood 123 (4), 570-581 (2014)
   PUBMED   24200680
REFERENCE   5  (bases 1 to 2231)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC120124.10, AK141754.1 and AK005431.1.
            
            Transcript Variant: This variant (2) lacks an alternate in-frame
            exon compared to variant 1. The resulting isoform (2) has the same
            N- and C-termini but is shorter compared to isoform 1. Variants 2
            and 5 both encode the same isoform (2).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141754.1, SRR7345562.2654244.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                AC120124.10        19207-19226         c
            21-1122             AK141754.1         7-1108
            1123-2231           AK005431.1         884-1992
FEATURES             Location/Qualifiers
     source          1..2231
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 37.06 cM"
     gene            1..2231
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /note="tetratricopeptide repeat domain 23"
                     /db_xref="GeneID:67009"
                     /db_xref="MGI:MGI:1914259"
     exon            1..436
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            437..636
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             457..1797
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     tetratricopeptide repeat protein 23; TPR repeat protein
                     23"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 23 isoform 2"
                     /protein_id="NP_001161947.1"
                     /db_xref="CCDS:CCDS52270.1"
                     /db_xref="GeneID:67009"
                     /db_xref="MGI:MGI:1914259"
                     /translation="MQESQDTHMSSHLDEVVAAVSVTSKNRIPNKLLQTALFQPPREK
                     LHLCEERAKSYSSSREYKQAIQELVRCVALTRICYGDWHWKLAEAYVNLAQGYLQLKG
                     LSLQAKQHAEKAKEILANSIESPCHNKTDIFKCSLELFYTLGRALLSLQKFKDASENL
                     IKAERLSKEMLQCGNIVKEEWIEIQSRIKLSFAQLYQGQKRSKEAFPFYQKALEYTEI
                     TKDEKSLECVQVLRELAGVEQALGLYAAAISHFSRAHLIILSKDPSPEEAADSAHFIA
                     RAAAASGMHDHRDVAEKYFQESMTSIKDSEGAERAKFLSIQDEFCSFLQTTGQKERAA
                     MILRESLEAKVGAFGDFSPEVAETYRALGRADLAQGNNSGAYAKLKKCVQIETFLYGS
                     QDKKTLATQHTIDTLSKISEAAGKSRQSVKAKVAFCTSAPQYGMPGKGRHSVAD"
     exon            637..760
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            761..911
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1037
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1038..1215
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1321
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..1449
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1599
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1682
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..2231
                     /gene="Ttc23"
                     /gene_synonym="1600012K10Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagaagcta tcattctttc tttggcctgg agttttgtta agtaccgggt tgctttatgg
       61 aaaaatgctg ggtttttttt aggacgaaac tgctctgttt agacttgtct gtggttatca
      121 ggctgtagaa tccttaactt gatacagagg gagccaaatt ggcaactcag attttcaaga
      181 gaactgtgaa aaggaaaagg actctctctc catgggaccg ctaaactcac aaaggatttt
      241 acgacaaagt tgcagatact gagccttaag gaaactttcc aggtgttttg ttttgctagt
      301 tttaaaggaa cgtccaaaga aaaccagagg aaacacctgg tgctgagcgt ggctggaggg
      361 agaggcatca gagctctttt gtctttagaa tgaaggtgga aatgcaattc ccaggttatc
      421 agtggaattt tgtaagagga caatgcgtat gagaatatgc aggagtccca ggacacccac
      481 atgtccagcc acctagacga agtcgttgct gctgtcagcg tcacttctaa aaacaggatc
      541 ccgaataagc tgcttcagac agcactgttc cagccccctc gagagaaact ccacctgtgt
      601 gaggagagag caaagtccta ctccagcagc cgagagtaca aacaggccat ccaggagctt
      661 gtgcgctgtg tggcactaac aagaatttgc tatggcgact ggcactggaa actagcggag
      721 gcgtatgtta atctggctca gggttacctg cagctgaaag ggttgtcact acaagcaaag
      781 cagcatgcag agaaagccaa ggagatcctg gccaactcca tcgagagtcc ctgtcacaac
      841 aaaacagata tcttcaagtg ttccctggag cttttctata ccctggggag agcgctgctc
      901 tcccttcaaa aatttaaaga cgcctcagag aacttgataa aagcagagag actttccaag
      961 gagatgctgc aatgtgggaa cattgtaaag gaagagtgga tagaaatcca gtctcgaatc
     1021 aagctgtcgt ttgcacagtt gtatcaaggt cagaagagat caaaagaagc tttcccgttc
     1081 tatcaaaagg ctttggaata taccgagatc accaaagatg aaaaaagtct tgagtgtgta
     1141 caagtcctga gggaactggc aggtgtggag caagccctag gactctacgc cgccgccatc
     1201 agtcatttct cacgggcaca tctcatcatc ctgagtaaag atccctcccc ggaggaggct
     1261 gcagactctg cacacttcat cgcccgggct gctgctgctt ctgggatgca cgaccaccgt
     1321 gatgtggccg agaaatactt tcaggaaagc atgacttcta tcaaggattc cgaaggagcg
     1381 gaaagagcca agttcctttc gattcaagat gagttttgca gttttctgca aaccaccgga
     1441 caaaaagaaa gagcggccat gatcctgaga gagtccctgg aagccaaagt aggagcattt
     1501 ggtgacttca gtcctgaggt ggcagaaacg taccgggccc tgggcagggc agacctggcg
     1561 cagggaaaca acagtggagc gtacgcgaag ctaaagaagt gtgtccagat tgagacgttc
     1621 ttgtatggat cacaggacaa gaagaccctg gccacccagc acaccataga cacactgtcc
     1681 aagatctccg aggctgccgg gaagtcaagg caatcggtga aagccaaagt agcattctgc
     1741 accagtgccc cccagtacgg catgccaggg aagggcaggc acagtgtagc agactgatgc
     1801 gcccatgtgc cgccccaaag aaagctccaa gaaagacttg gcattgcttg taggatgctg
     1861 aacaaacctc tctccagctc gaaggtgaag ttcagcagcc actgcaggtt tttaaggctg
     1921 tttacttcag aatgcaatgg cagtaccatg aatcttccac accccaattg tgaatgccct
     1981 ttggggtgat atggtgctct tggttatctt ctttcaccaa ggagactctc ctctgtcatc
     2041 tctgccgtgg ctgaaacact cttcccaagt tggagcttct tgacaggaaa ggagactcac
     2101 ctggtgacag gcagggctcc tgctccatcc agagccacat ctggggcagc gagaccctgc
     2161 acaaagcctc cctcgtatga aagtaatagt aactgagaag aaactaccaa taaagagatg
     2221 cttgtgctag c
//
