LOCUS       NM_177384               2938 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus tetratricopeptide repeat domain 16 (Ttc16), transcript
            variant 1, mRNA.
ACCESSION   NM_177384
VERSION     NM_177384.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2938)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK089384.1, AK133273.1 and AI661256.1.
            
            On Mar 14, 2014 this sequence version replaced NM_177384.2.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK133273.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-223               AK089384.1         2-224
            224-2728            AK133273.1         2-2506
            2729-2938           AI661256.1         1-210               c
FEATURES             Location/Qualifiers
     source          1..2938
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 22.09 cM"
     gene            1..2938
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /note="tetratricopeptide repeat domain 16"
                     /db_xref="GeneID:338348"
                     /db_xref="MGI:MGI:2443048"
     exon            1..303
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             286..2760
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /note="isoform a is encoded by transcript variant 1;
                     tetratricopeptide repeat protein 16; TPR repeat protein
                     16"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 16 isoform a"
                     /protein_id="NP_796358.2"
                     /db_xref="CCDS:CCDS15930.2"
                     /db_xref="GeneID:338348"
                     /db_xref="MGI:MGI:2443048"
                     /translation="MTDRSKTQRTPSASSSRTGLLKEPHSARSQKTPKLKVPEAPEKI
                     LRRIFGTSHVFYVMTDPTKRRMIGSTVPAKVREYYNQGHQCLLQEDWEMSVLFFSRAL
                     HLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGQCL
                     YELCDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASA
                     DVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDASTLA
                     VQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDTQD
                     NLVKQAQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQL
                     GNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGFCQQKHRQFQTAEEHFSEAIRHS
                     PQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPEYPKMAAVMNTLFPSMTVENVLK
                     SQVAELAKLQLSRMIENGPKNIYPQSTVVQRLLERRKAQVLVKLWKQERLGTPEEEVT
                     LYQAPQLAEEKKVKTARRRTSLTDSYADQTSSGSVFSIVSISTSGPEMSTSQEYKSSS
                     HTAIESSESTLLKPQLSVPRKSQELTWSPKVVQAVTENLIQNATEVTPAYGQRDSKKA
                     TQVPKPKKTEDPKDPSQSTSTTEAPEGPRPSKSRSTLSVKERIRRAKAVRAQGWKLKA
                     QRSSQKVTKTPSLTHSTTHSDIGESANDTPGQTPWPSKAADSLSFSEISSTDLSSSES
                     FLELTNLLTQEVQQIPGDREKLTSDD"
     exon            304..351
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            352..518
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            519..609
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            610..753
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            754..854
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            855..984
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1199
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1444
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1586
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1587..1752
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1753..1895
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1896..2019
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2095
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2096..2924
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2905..2910
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2924
                     /gene="Ttc16"
                     /gene_synonym="1200002K10Rik"
                     /note="major polyA site"
ORIGIN      
        1 gcattcctcc gcgacgcgtc accctgtatg gctcagcctt tgctcggcct ttgctcgagg
       61 gctggtacct cgttaagttt ctaccctggc ccgcgtcggc gtgcactgcc cataggttct
      121 ttccttgact taggccttgg cttgccttgc tgagtttcta gtgactctcg gaggcggggc
      181 caagtgggcg gggcctatgg acatcgtgga cctggtgcct agcaacaacg gagctaggga
      241 acctcagagt atgcttagcc cagaagttag cctagaaacc tggccatgac agacagaagc
      301 aagactcaga gaactccatc tgcctctagc tctagaacgg ggttattaaa ggagcctcac
      361 agtgcccgtt cccagaaaac tccaaagcta aaggttcctg aagccccaga gaagatcctg
      421 cgacgcatct ttgggaccag tcatgtgttc tatgttatga cagatcctac aaaacgaagg
      481 atgataggat caacagtgcc tgccaaagtc agagagtact ataaccaagg ccatcagtgc
      541 ctcctacaag aggactggga gatgtctgtg ctgttcttct cccgtgccct ccacctggac
      601 cccaaactgg tagacttcta tgtattccgt gctgaggcct tcatccaact ctgtgacttc
      661 tcctctgccc tccagaacct ccgcagggcc tactcctatg acccagggaa taacaagtac
      721 ctgaaccggc tggcctttgt gctctaccta cagggtcagt gcctgtatga gctgtgtgac
      781 ttccaggaag ccctctgtgt cttcctgcaa gcctccgacc tccagcccca aaacgcttcc
      841 ttcagttacc gatgcatggc ctgcctgctg gccctcaagc ggtatcacga ctgcctcgcc
      901 ctcatcacta gggaggtgaa gcagggcagg gccagcgctg atgtctacat cctccgggct
      961 cggctctaca acttcttcca gaaggccaag ctctgctatc aggaccttcg aagcgccttg
     1021 ctcctagatc ccttgcacgc acaggccaaa gggctactcc agaagatggt ggaccaggcc
     1081 aagcagtctc tccaagatgc cagcaccctg gccgtgcagg gcaaggtgca ccgtgcactg
     1141 aagtgcatca actgtgccat tgagaacaat cccctggatc ccaacttctt cttcttccgg
     1201 ggcaccttgc gtagacggct ccagcaattt gaccatgctg tggaagactt cctgaaggca
     1261 atggacatgg tgactgacac ccaggacaac ctagtgaagc aggcgcagcg tcagctgctg
     1321 ctgacttaca atgactttgc tgtgcactgc tacaaccatg gtgcctatca ggagggcgtg
     1381 ctgctgctga acaaggctat cagagacgag cagaatgaga agggcttgta catcaaccgt
     1441 ggggattgct tcttccagct gggcaacctg gccttcgcgg aggctgacta caagcaagcg
     1501 ctggccctga gcccgctgga tgaaggagcc aacttgcgca tgggtgtgct gcaggagaag
     1561 ctgggcttct gccagcagaa acacaggcag ttccagacag cagaggagca cttctcggag
     1621 gccataaggc acagccctca gaaaccacag tactacctgc accgggccaa gtgccgacag
     1681 ttcctgcaga acactctggg ggcccgcctg gatgtcgcta ctgtactgct tctcaatccc
     1741 gagtatccca agatggctgc agtgatgaac accctctttc ctagcatgac tgtggagaat
     1801 gtgcttaagt cccaagtggc cgaactggcc aagctccagc taagtcggat gatagaaaat
     1861 gggccgaaga acatctaccc tcagagcact gtggtgcagc ggttattgga acgcaggaaa
     1921 gcccaagtcc tggtgaagct ctggaagcag gaacgtcttg ggacccctga agaggaagtg
     1981 actctttacc aggctccgca gctggcagag gaaaaaaagg tgaaaaccgc tcgcagaagg
     2041 acatccctga cagacagcta tgcggaccag acctcctcag gctccgtctt tagcattgtg
     2101 agcatcagca cgtcggggcc agagatgtca accagtcagg agtataagag ctcttcccac
     2161 acggctatag aatcctctga gtccacactg ctaaagcctc agctctcagt acccaggaag
     2221 agccaggaac tgacctggag ccccaaggtc gtccaggcag tcacagagaa cctaatccag
     2281 aacgccactg aggtcacacc tgcctatggc caaagggact ccaaaaaggc cacccaagtc
     2341 ccaaagccca agaagacaga ggatcccaag gatcctagcc agagcaccag cacgacagaa
     2401 gcccctgagg gcccaaggcc tagcaagtcc aggtctaccc tgagcgtaaa ggagagaatc
     2461 agaagagcta aggctgttcg cgcccagggc tggaaactca aggcccagcg cagcagccag
     2521 aaagtaacaa agactcccag cctgacccac agcacgaccc atagtgacat tggtgagagt
     2581 gccaatgata ccccgggcca gactccatgg cccagcaagg ctgctgatag cttaagcttc
     2641 agtgagatct cgtcaacaga tctcagcagt agtgaaagct tcttggaact gactaacctt
     2701 ttaactcagg aagtccaaca gatcccagga gacagagaga agctcacctc tgacgattaa
     2761 ctactccctc aaagggccaa tgaagccctt cctgagcaat gaacagattt cagccaagct
     2821 gcctcctccc aggacagtaa gaaactttgg tcaatgttct aataccaagg ctaagtttat
     2881 ttaatctctg ttctcttgta caaaattaaa aactttgaaa ttcaaaaaaa aaaaaaaa
//
