LOCUS       NM_172770               3630 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus tetratricopeptide repeat domain 12 (Ttc12), mRNA.
ACCESSION   NM_172770 XM_917199
VERSION     NM_172770.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3630)
  AUTHORS   Hoh,R.A., Stowe,T.R., Turk,E. and Stearns,T.
  TITLE     Transcriptional program of ciliated epithelial cells reveals new
            cilium and centrosome components and links to human disease
  JOURNAL   PLoS One 7 (12), e52166 (2012)
   PUBMED   23300604
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC117630.11
            and AC167980.3.
            
            On May 2, 2007 this sequence version replaced NM_172770.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK054350.1, BC056616.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-80                AC117630.11        86826-86905
            81-153              AC117630.11        88309-88381
            154-314             AC117630.11        100508-100668
            315-336             AC117630.11        101168-101189
            337-414             AC117630.11        101848-101925
            415-536             AC117630.11        102701-102822
            537-596             AC117630.11        106220-106279
            597-668             AC167980.3         218984-219055       c
            669-729             AC167980.3         217244-217304       c
            730-918             AC167980.3         216590-216778       c
            919-988             AC167980.3         215427-215496       c
            989-1077            AC167980.3         214455-214543       c
            1078-1246           AC167980.3         211918-212086       c
            1247-1339           AC167980.3         206521-206613       c
            1340-1400           AC167980.3         205119-205179       c
            1401-1538           AC167980.3         204336-204473       c
            1539-1637           AC167980.3         203779-203877       c
            1638-1706           AC167980.3         203262-203330       c
            1707-1808           AC167980.3         201696-201797       c
            1809-1908           AC167980.3         200431-200530       c
            1909-2134           AC167980.3         198751-198976       c
            2135-3630           AC167980.3         195555-197050       c
FEATURES             Location/Qualifiers
     source          1..3630
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 26.83 cM"
     gene            1..3630
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /note="tetratricopeptide repeat domain 12"
                     /db_xref="GeneID:235330"
                     /db_xref="MGI:MGI:2444588"
     exon            1..80
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            81..153
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..2210
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /note="TPR repeat protein 12"
                     /codon_start=1
                     /product="tetratricopeptide repeat protein 12"
                     /protein_id="NP_766358.1"
                     /db_xref="CCDS:CCDS23163.1"
                     /db_xref="GeneID:235330"
                     /db_xref="MGI:MGI:2444588"
                     /translation="MADDQERDLQRFLENVDEITSLIQEMNSDDPFIQQKAVLDSEKK
                     LLLMEREQEEDGCRTTLNKTMISPPQTPENADEMSPDAFLASVEKDAKERAKRRRENR
                     VLADALKEKGNEAFVRGDYETAIFFYSEGLGKLKDMKVLYTNRAQAFIKLGDYQKALV
                     DCDWALKCDENCTKAYFHMGKAHVALKNYSKAKECYQKIEEINPKLKAQVKEHLNQVT
                     LREKADLQEKEAQESLDSGKNTAVTTKNLLETLSKPGQTPLFYAGGIEILTEMMADCT
                     ERTLFRTYGGFSTISDHEVIRRCLFLTGKDAVEEVLCVSVLKLWQEVCVDNEENQRLL
                     VTHPDMARLLPSFMTSRILVIQQQSLDLLLQLTQTENGRNQVIKHLDMTQLCEALLSF
                     LAFSDKKANTAIGILTDLALEERFQVWFQTNLPDVLPALTGALNREPKITSPSALCQC
                     IALLGNISAEPTARKHMIAHEEFGNACLDLLVKCEEDMDLFREITYTLLGLIMNLCLE
                     ITFLSEMWVVKMSRKCLSLLNSKDGGILTRAAGVLSRTLSSSQTIVEEALTAGVVKKM
                     IKFLRMGGQTASRYAIKILAICTNSCHAAREEVVRLDKKFDLLMLLLASEDEILAGNA
                     ALCLGNCMEVPSAAPSLLKTDIVRVLLKLAGSDSKETGVQLNAGIALGKLCTAEPRFA
                     AQLRELHGIQVLNSTMKHLNDS"
     exon            154..314
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            315..336
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            337..414
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            415..536
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            537..596
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            597..668
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            669..729
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            730..918
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            919..988
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1077
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1246
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1247..1339
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1340..1400
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1538
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1637
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1638..1706
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1808
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1809..1908
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..2134
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2135..3630
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2296..2301
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2327
                     /gene="Ttc12"
                     /gene_synonym="E330017O07Rik"
                     /note="major polyA site"
ORIGIN      
        1 aaggccccgc ctctccccag cgaaagccag tcacagcctg tcctcagctt ccacttcccg
       61 tccgatcctg ggcactaaag agatttgtgt ctgcgatggc tgatgatcaa gagagagact
      121 tgcagagatt tctggaaaat gtggatgaaa taaccagttt aatccaagag atgaattctg
      181 atgatccctt catacagcag aaagctgtcc tggactcgga aaagaaactc ctgctgatgg
      241 agagagagca agaggaggac gggtgcagga ccactctgaa taagaccatg atcagtcctc
      301 cacaaactcc cgagaatgca gatgaaatga gcccagatgc cttcttggca tccgtggaga
      361 aggacgccaa ggaacgagcc aagagaagac gagaaaacag agtcctggca gatgccctga
      421 aggagaaggg gaacgaggcc tttgtcaggg gcgactatga aacagccata ttcttctaca
      481 gtgagggctt ggggaagctc aaggacatga aggtgctgta caccaaccga gcccaggctt
      541 ttataaaact tggggactat cagaaggctc ttgtggattg tgactgggct ctgaagtgtg
      601 atgagaattg tacaaaggcc tatttccaca tggggaaagc ccacgtggcc ctgaagaact
      661 acagcaaggc taaagaatgt tatcagaaga ttgaagagat aaaccccaag ctgaaggcac
      721 aggtgaaaga acacctaaat caagtaactc ttcgagagaa agcagatctt caagagaagg
      781 aagcccaaga atctctggat tcaggaaaga acacagcagt gacgaccaaa aatctcctgg
      841 aaaccctatc caagcctggc cagacaccct tgttctatgc aggaggcatt gagattctga
      901 cagaaatgat ggctgactgc acagagcgaa cgttgttcag aacctacggt ggattcagca
      961 ccatcagtga ccatgaggtc atcagaaggt gcctcttctt aacagggaag gatgcagtcg
     1021 aggaggtgct ttgcgtatct gttctaaaac tctggcagga ggtttgcgtc gacaacgagg
     1081 agaaccagcg cctgcttgtg acccaccctg atatggccag gctgctgcct tccttcatga
     1141 cttccagaat cctggtgatt caacagcaga gcctggacct actgctgcag ctcactcaga
     1201 cggagaatgg ccggaaccaa gtgatcaagc accttgacat gacccaactg tgtgaagcac
     1261 tgctgtcatt tcttgccttc tctgataaga aggccaatac agccatcgga atactcacag
     1321 acttggctct agaagaaaga ttccaagtct ggttccagac caaccttcca gatgtcctcc
     1381 ctgctctcac gggagctctg aatcgagagc ccaagataac cagcccctct gccctctgcc
     1441 agtgcattgc tctgttggga aacatcagcg ctgagccaac tgccagaaaa cacatgatag
     1501 ctcatgaaga atttgggaat gcctgcttgg acctcctggt caagtgtgaa gaggacatgg
     1561 acttattcag agagatcaca tataccctcc taggactcat catgaacttg tgtcttgaaa
     1621 tcaccttcct ctctgagatg tgggttgtga agatgagccg gaagtgcctg tctctactga
     1681 acagcaagga tggaggaatc ttaacaagag cggcaggtgt tctgagccgg accctttctt
     1741 cctctcagac cattgtggag gaggccctga cagcaggagt ggtcaagaaa atgattaaat
     1801 tcctgaggat gggaggccag actgcatcac gttacgccat aaagatactg gctatctgca
     1861 cgaacagctg tcatgcagct cgggaagaag tagtgagact tgataaaaag tttgaccttt
     1921 tgatgctgct gcttgcctct gaggatgaaa ttctggcggg caatgctgcc ctctgccttg
     1981 gcaactgcat ggaagtgccc agtgcagccc cttccttgct gaagacggac atcgtgaggg
     2041 tgctcttgaa gctggcaggc agcgactcaa aggagacagg cgtacagctg aatgcaggca
     2101 tcgctctggg gaagctgtgc actgctgagc ccaggtttgc tgcccaactg cgagagcttc
     2161 acgggataca agttctcaac tctacaatga aacacttgaa tgattcttga aagacacggt
     2221 gccagtgtaa aagcctgtga gcacacacac acacacacac acacacaact ctgggccagg
     2281 ggtcactgct ctgctaataa attcttttta aatatttagc tccaaaactg gatgtctgcc
     2341 gggtttttgc tgggaagaag agagcaggtg gctaccacag tagaaactgc tgctctaaca
     2401 actgatgctt gctctagcat ccatctccca tgcctttgac ctgctccttc attttctact
     2461 gaggctggaa aacagcctat caaaagcctc atttcccagg cacccttgca gcaacaccac
     2521 tagatgagaa ctagatcctg agggaagcat caggggtgtt tggtactgac accttagcat
     2581 ctgcctgcag cactcagccc tataaaagac tggtggtagc accagggtgg cagcagctac
     2641 ctgaatccca actgcatctg tggcatgtgc ttttgaatcc agtgggttaa gtgatgatgg
     2701 gtggctcccc tgacaaggga gctgtttcta gtcctgggcc tgggggtcag cattagcatc
     2761 tggctgcttt cttacaagta ccccatgtta ggtgtaagat ggttctggac tgaaagtgag
     2821 agaacacagg cttttatttg cagaaaccca gttggaagtc tggatgaaaa tcactaacct
     2881 ggagccctct gtgtgggacc agtgcactgt gggcagctgg taagagctca ctggagtatt
     2941 ctacaatggg gctgtaacag tgtccccagg tgccaggcag gtgccaggcc tcagcagaga
     3001 aggtgggacc tgcccattcc atggcctcat gcaaacaaac ctccttcaag cagccaaatt
     3061 gcaagggaga tgtgtgacgg taaacagagc agagaggaaa agtagaggtt gcagaatctg
     3121 cagctttcaa agaactcggc agggcttgga aggtggcatc ggggtgcaga atcaacaggc
     3181 tggtctccat tgcaaggttc atgcctctct catgctgcta cattcctcct ctctgactct
     3241 gaaaatggct gccgtaggta gaaccccatc cccaaagagt ggggactgtc acattccact
     3301 gtgcttgaga gttcacgcac agagttgtaa tcttcacgct ggcggtgggg tggttgcaca
     3361 cactcgacag gtggagagac atgccttaca aactagccat ctcgcatctc gtaacctcac
     3421 aaggatacca tgaggcagat attgtcttca ctatagatgt aaagaaacca agacttccat
     3481 gcctggggcc atgtattctg taaatagagg agtcagaagt taagggcaaa ctaaagactc
     3541 aaaagtttgt ttgtttgttt ttaacttttt tctaatgtaa aacatttctc tccttgttga
     3601 atgtggcttg caagaaacat ctaatttttt
//
