LOCUS       NM_001164525             551 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus thiosulfate sulfurtransferase (rhodanese)-like domain
            containing 1 (Tstd1), mRNA.
ACCESSION   NM_001164525 XM_129558 XM_917811
VERSION     NM_001164525.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 551)
  AUTHORS   Zheng,A., Li,H., Feng,Z. and Liu,J.
  TITLE     Integrative Analyses Reveal Tstd1 as a Potential Modulator of HDL
            Cholesterol and Mitochondrial Function in Mice
  JOURNAL   Cells 10 (11), 2976 (2021)
   PUBMED   34831199
  REMARK    GeneRIF: Integrative Analyses Reveal Tstd1 as a Potential Modulator
            of HDL Cholesterol and Mitochondrial Function in Mice.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 551)
  AUTHORS   Wenzel,K., Felix,S.B., Flachmeier,C., Heere,P., Schulze,W.,
            Grunewald,I., Pankow,H., Hewelt,A., Scherneck,S., Bauer,D. and
            Hoehe,M.R.
  TITLE     Identification and characterization of KAT, a novel gene
            preferentially expressed in several human cancer cell lines
  JOURNAL   Biol Chem 384 (5), 763-775 (2003)
   PUBMED   12817473
  REMARK    GeneRIF: compares human Tstd1 amino acid sequence to that of
            orthologs, including mouse.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC087229.27 and BY720852.1.
            
            On or before Sep 3, 2009 this sequence version replaced
            XM_917811.2, XM_129558.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY720852.1, CJ235542.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AC087229.27        164405-164436
            33-519              BY720852.1         2-488
            520-551             AC087229.27        165693-165724
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 79.41 cM"
     gene            1..551
                     /gene="Tstd1"
                     /gene_synonym="EG226654; Gm4848; KAT"
                     /note="thiosulfate sulfurtransferase (rhodanese)-like
                     domain containing 1"
                     /db_xref="GeneID:226654"
                     /db_xref="MGI:MGI:3648482"
     exon            1..103
                     /gene="Tstd1"
                     /gene_synonym="EG226654; Gm4848; KAT"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..441
                     /gene="Tstd1"
                     /gene_synonym="EG226654; Gm4848; KAT"
                     /EC_number="2.8.1.1"
                     /codon_start=1
                     /product="thiosulfate:glutathione sulfurtransferase"
                     /protein_id="NP_001157997.1"
                     /db_xref="CCDS:CCDS48443.1"
                     /db_xref="GeneID:226654"
                     /db_xref="MGI:MGI:3648482"
                     /translation="MLRLAVLRHSHTSAAAGTMAGVPTVSFSELRSLVASGRARLFDV
                     RSPEEAAAGTIPGALNIPVSELEIALNMDPAAFQTLYCAEKPKLEDKNLIFFCQMGRR
                     GLQATQLAQGLGYTGARNYAGAYKEWLEKQG"
     exon            104..226
                     /gene="Tstd1"
                     /gene_synonym="EG226654; Gm4848; KAT"
                     /inference="alignment:Splign:2.1.0"
     exon            227..389
                     /gene="Tstd1"
                     /gene_synonym="EG226654; Gm4848; KAT"
                     /inference="alignment:Splign:2.1.0"
     exon            390..551
                     /gene="Tstd1"
                     /gene_synonym="EG226654; Gm4848; KAT"
                     /inference="alignment:Splign:2.1.0"
     regulatory      529..534
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tstd1"
                     /gene_synonym="EG226654; Gm4848; KAT"
                     /note="hexamer: AATAAA"
     polyA_site      550
                     /gene="Tstd1"
                     /gene_synonym="EG226654; Gm4848; KAT"
                     /note="major polyA site"
ORIGIN      
        1 ggttccggtc tctggttggg ctctgggagg gtgagggaga tgcttcggct tgcagttctg
       61 cgtcacagtc acacaagtgc ggctgcagga accatggctg gagtgcctac agtctccttc
      121 tctgagctcc gttcactcgt agcctcaggc agggccaggc tcttcgacgt tcgatctcca
      181 gaggaggcag cagctggtac cattcctggg gcactcaaca tccctgtgtc tgaattggaa
      241 atcgccttga acatggaccc agctgctttt cagactctgt actgtgctga gaagccaaag
      301 ctagaagaca agaatcttat tttcttctgt cagatgggca ggcggggtct ccaggccaca
      361 caactggcac aaggtcttgg ctatacaggg gctcggaact atgccggggc ctataaagag
      421 tggctggaga aacagggcta gataaaaggc tcaccagttt gtggctgttc tcagactacc
      481 ttgctgggct aggcaaatcc ttgtagtgct tcacacatga aaaactcaaa taaaaagtac
      541 acttaatgaa g
//
