LOCUS       NM_026676               1224 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus TSR3 20S rRNA accumulation (Tsr3), transcript variant
            1, mRNA.
ACCESSION   NM_026676
VERSION     NM_026676.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1224)
  AUTHORS   Shimogori,T., Lee,D.A., Miranda-Angulo,A., Yang,Y., Wang,H.,
            Jiang,L., Yoshida,A.C., Kataoka,A., Mashiko,H., Avetisyan,M.,
            Qi,L., Qian,J. and Blackshaw,S.
  TITLE     A genomic atlas of mouse hypothalamic development
  JOURNAL   Nat Neurosci 13 (6), 767-775 (2010)
   PUBMED   20436479
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK158743.1 and BC089019.1.
            
            On Aug 1, 2009 this sequence version replaced NM_026676.2.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089019.1, AK158743.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1191              AK158743.1         2-1192
            1192-1224           BC089019.1         1141-1173
FEATURES             Location/Qualifiers
     source          1..1224
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.53 cM"
     gene            1..1224
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /note="TSR3 20S rRNA accumulation"
                     /db_xref="GeneID:68327"
                     /db_xref="MGI:MGI:1915577"
     exon            1..195
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..1055
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /EC_number="2.5.1.157"
                     /note="isoform 1 is encoded by transcript variant 1;
                     probable ribosome biogenesis protein C16orf42 homolog;
                     ribosome biogenesis protein TSR3 homolog; 20S S rRNA
                     accumulation protein 3 homolog; 18S rRNA
                     aminocarboxypropyltransferase"
                     /codon_start=1
                     /product="18S rRNA aminocarboxypropyltransferase isoform
                     1"
                     /protein_id="NP_080952.2"
                     /db_xref="CCDS:CCDS28512.1"
                     /db_xref="GeneID:68327"
                     /db_xref="MGI:MGI:1915577"
                     /translation="MGRKKVARGSRKESGRVRRPSGRSLDAFAEEVGAALRASVQPEE
                     AEDQGGPGPAALPCALAMWELGHCDPKRCTGRKLARLGLVRCLRLSQRFGGLVLSPVG
                     TEYVSPADRQLVAQSGVAVIDCSWAKLDDTPFQKMRGSHLRLLPYLVAANPVNYGRPC
                     KLSCVEAFAAAFCIVGFSDLAVILLRKFKWGKGFLDLNRELLDKYAACRGPEEVLQAE
                     QGYLASTRDTPEEDIDPFDVDSGREFVNLNRPVASTRLPEDMDDTDGSEEHSEDSEED
                     SDECEEPGPGANGGDSNYSGAEETPEQEAQARDSTEIWKGIKKRQRD"
     exon            196..415
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            416..609
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            610..783
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            784..847
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            848..1193
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1170..1175
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1193
                     /gene="Tsr3"
                     /gene_synonym="0610007P22Rik; 1110014B11Rik"
                     /note="major polyA site"
ORIGIN      
        1 ggaagctgtg cgagcgcgca cgcgcgcacg ctcttgaaca aacgctggag ctgaggattt
       61 catctcggat ttcatctaac attatgggcc gcaagaaagt tgctcgcgga tccaggaaag
      121 agagcggtcg tgttcggcga ccctctggcc gctctctgga tgctttcgct gaagaggtgg
      181 gcgctgcgct gcgtgcatcc gtgcagcccg aggaggccga ggaccagggc ggcccgggcc
      241 ctgcggcgct gccttgtgcc ttggctatgt gggagcttgg tcactgcgac cccaagcgct
      301 gcacgggccg caaactggcc cgtctgggtc tggtgcgctg cctgcgcctg agccaaaggt
      361 ttggcggtct ggtgctcagc ccagtaggca ctgagtacgt gtctccggca gacagacagc
      421 tggtggcaca gtcaggggtc gcagtcatag actgctcctg ggccaaactg gacgacacac
      481 cctttcagaa gatgcgaggg agccacttgc ggctcctgcc ttacctcgta gctgccaacc
      541 ctgtaaacta tggccggccc tgcaaacttt cctgtgtgga agctttcgct gctgccttct
      601 gcatcgtagg cttttcagac cttgctgtca ttttgcttcg gaagtttaag tggggcaagg
      661 gcttcctgga cctgaaccgg gagctcctgg ataagtacgc agcttgccgt ggcccggagg
      721 aggtgttgca ggctgaacag gggtacttgg ctagcaccag ggacacgcct gaagaggaca
      781 tcgatccctt tgacgtggac tcagggcggg agtttgtgaa tctcaacagg cccgtggcca
      841 gcacccggct acctgaggac atggatgaca ctgatgggtc tgaggagcac agtgaagatt
      901 ctgaggagga cagtgatgag tgtgaggaac caggacctgg tgctaatgga ggagacagca
      961 actactctgg agctgaagag accccagaac aagaggctca agccagagac tccactgaaa
     1021 tttggaaagg gatcaagaaa cgacagagag actgaaggtc acaaacatat tattgaagct
     1081 ggtgtgcatt attcagaagt ggcagtagga cctggggatg gacgggcctg ctgggacaac
     1141 cttgtttagt gtcctgcctt agtgctctca ataaaaccaa ggagaccccg ctaaaaaaaa
     1201 aaaaaaaaaa aaaaaaaaaa aaaa
//
