LOCUS       NM_177325               3395 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus TSR1 20S rRNA accumulation (Tsr1), mRNA.
ACCESSION   NM_177325
VERSION     NM_177325.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3395)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3395)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   3  (bases 1 to 3395)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 3395)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CD547366.1, AK129350.1 and BF455129.1.
            
            On Mar 2, 2007 this sequence version replaced NM_177325.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660815.71841.1, AK154063.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-476               CD547366.1         1-476
            477-3383            AK129350.1         431-3337
            3384-3395           BF455129.1         1-12                c
FEATURES             Location/Qualifiers
     source          1..3395
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.76 cM"
     gene            1..3395
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /note="TSR1 20S rRNA accumulation"
                     /db_xref="GeneID:104662"
                     /db_xref="MGI:MGI:2144566"
     exon            1..136
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..2451
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /note="TSR1, 20S rRNA accumulation, homolog"
                     /codon_start=1
                     /product="pre-rRNA-processing protein TSR1 homolog"
                     /protein_id="NP_796299.2"
                     /db_xref="CCDS:CCDS36225.1"
                     /db_xref="GeneID:104662"
                     /db_xref="MGI:MGI:2144566"
                     /translation="MAAHRSGPLKQQNKAHKGGRHHGGGSAQRDSKGRVGPKILCKKL
                     KRQLSRIDQRHRASQLRKQKRESVLAEKRQLGSKDGPPHQVLVVPLHSRISLPEAFKL
                     LQNEDLGTVYLSERGSTQSFMLLCPSLKHRWFFTYARPGDLHTLLDMAKVADTILFLL
                     DPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGLSGFPPKKQIDARKKLSKMVEKRFPED
                     KLLLLDTQQESGMLLRQLANQKQRHLAFRDRRAYLFAHVADFVPSEESDLVGTLKISG
                     YVRGRTLNVNSLLHIVGHGDFQMNQIDAPVDPFPLNPRVIKSQKKPNMAMEVCVTDAA
                     PDMEEDLKVLMKADPDHQESLQTEAIPDPMEGEQTWPTEEELDEADDLLKQRSRVVKK
                     VPKGTSSYQAEWILDEGDESDGEGGEYDDIQHEGFMEEESQDGSGEEEEEECETMTLG
                     ESVRDDLYDEKVDAEDEERMLEKYKQERLEEMFPDEMDTPRDVAARIRFQKYRGLKSF
                     RTSPWDPKENLPRDYARIFQFQNFVNTRKRIFKEIEEKEAEGAEVGWYVTLHVSDVPV
                     SVVEYFRQGAPLIAFSLLPYEQKMSVLNMVVSRNPGNTEPVKAKEELIFHCGFRRFRA
                     SPLFSQHTAADKHKFQRFLTADAAFVVTVFAPITFPPASVLLFKQRRNGMHSLIATGH
                     LFSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVMWFKPVELRTKWGRRGHI
                     KEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWVKSDISSTVS
                     EVDME"
     exon            137..240
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            241..460
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            461..595
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            596..1020
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1180
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..1338
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1532
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1695
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            1696..1806
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            1807..1939
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            1940..2056
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            2057..2197
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            2198..2272
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     exon            2273..3385
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3365..3370
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /note="hexamer: AATAAA"
     polyA_site      3385
                     /gene="Tsr1"
                     /gene_synonym="mKIAA1401"
                     /note="major polyA site"
ORIGIN      
        1 cggaagtaga gttcacttgg tgcacacgtg gactgcagaa tggcggctca ccgctccggg
       61 ccgctgaagc agcagaataa agctcataaa ggcgggcggc atcacggcgg tgggtccgca
      121 caacgggaca gcaaaggccg ggtaggaccg aaaatcctct gcaagaagct gaagaggcag
      181 ctcagccgaa tagaccagag gcatcgcgcc agccagctcc gaaagcaaaa gagggagtcg
      241 gttctggccg agaagaggca gctgggcagc aaggatggtc ctccacatca ggtgctggtg
      301 gtgcctctgc acagcaggat ttcccttcca gaggcattta aactgcttca gaatgaagac
      361 ttgggaacgg tgtatttgag tgaacgggga agcacccaga gttttatgct tctgtgccct
      421 agcttgaaac atcgatggtt tttcacatat gcaagaccag gggatctgca tactctgtta
      481 gacatggcta aagtcgctga taccattctg ttcctcctgg acccactaga aggctgggac
      541 agtacggggg attattgcct gtcttgcctt tttgctcagg gccttcccac ctatacacta
      601 gctgtccagg gcctttctgg cttcccacca aagaaacaaa tagatgcccg aaagaagcta
      661 agtaaaatgg tggagaaacg cttccctgaa gacaaacttc tgctcctaga cacgcagcag
      721 gaatcaggaa tgctacttag acagttggct aaccagaagc aacggcatct tgcttttcgg
      781 gatcggcgag cttacttgtt tgcccatgtt gctgacttcg tgcctagtga ggagagtgac
      841 ttagtgggca ccttgaaaat ctcaggctat gttcgtggga ggactctgaa tgtaaatagc
      901 ttgctgcata tcgttggaca cggtgatttc caaatgaatc aaatagatgc tcctgtggat
      961 ccgttccctt taaatcctag agtgattaaa tcccagaaga aaccaaacat ggcaatggag
     1021 gtttgtgtta cagatgctgc tcctgacatg gaagaagacc ttaaggttct gatgaaggca
     1081 gaccctgatc accaggagtc tttacaaaca gaggctattc cagatcctat ggaaggagag
     1141 cagacctggc ccactgagga agagctggat gaggcagatg acttactgaa gcaacggtcc
     1201 agagtggtaa agaaggtccc taaaggaaca tccagttacc aggctgagtg gattctggat
     1261 gaaggtgatg aaagtgatgg ggaaggtggt gaatatgatg atatacaaca cgaaggtttc
     1321 atggaagagg agtctcagga tgggagtggt gaggaagagg aggaagaatg tgaaactatg
     1381 actctcgggg agtctgtgcg tgacgatcta tacgatgaga aagtagatgc agaggacgag
     1441 gagagaatgt tggagaaata taaacaagaa agactggaag aaatgtttcc agatgaaatg
     1501 gatacccccc gtgatgtagc tgctagaatt cgatttcaga aatatagagg cctcaagagt
     1561 ttccggacat ctccttggga tcctaaagaa aaccttccta gagattatgc tcggatattt
     1621 cagtttcaga attttgttaa tactagaaaa agaattttta aagagattga ggaaaaagaa
     1681 gctgaaggag ctgaggtggg ctggtatgtc acactccatg tttctgatgt ccctgtctca
     1741 gtggttgagt atttcaggca aggagcgccc ttgattgcat tttctttgct accttatgaa
     1801 cagaagatgt ctgtattgaa catggtggtg agccggaacc ctggcaacac ggaacctgtg
     1861 aaggcgaaag aagaattgat cttccactgt gggttcaggc gcttccgagc ttcgcctttg
     1921 ttctctcagc acacagcagc tgataaacat aaatttcaaa gattcctgac tgctgatgct
     1981 gccttcgtgg tgacagtgtt tgcgccaatc acgttccctc ctgcatctgt gctgcttttc
     2041 aagcagagaa gaaatggaat gcacagcctc atcgctacag gccatctgtt ttcagtggac
     2101 ccagacagga tggtcataaa gagagtggtt ctaagtggtc atccttttaa aatatttacc
     2161 aagatggcag tagtgcggta catgttcttc aacagagagg atgtgatgtg gtttaagcct
     2221 gtggaactga gaaccaagtg gggccgccgg ggacatatca aagagcctct aggtacccat
     2281 ggccatatga agtgcagttt tgatgggaag ctgaaatctc aggacacagt attaatgaat
     2341 ctctataagc gagtatttcc caagtggact tatgacccat atgtaccaga gccagtacct
     2401 tgggttaaaa gtgacatctc ttcaacagtg tctgaagtag acatggagta agagactcag
     2461 ttgggttctg tctctactgc aaccaaccaa aactccagtg ttggagtctg ggttgtgacc
     2521 aggcagcttg tgctctgtat ttcagttgtc catgtctctg ctaagtacag aatttacatg
     2581 attacttaca ctttcttcat taggattttg aacataattt ttaaagggaa gatggaaaca
     2641 aaattttcat ctagagacaa tcttgcctga atttaaacag aaaccgtctg gtaaggagct
     2701 ggccgttcag cctgccccac ccagttcagg gaggttaggt ctacattccc cccactgagt
     2761 acaatgcaga cgttctttac ttctggagag actgtttgga aatgctgaga cagcactgca
     2821 gccagtgcca cgccagcagt cggctcaatg agcagtttca ttctccccca caccagctgg
     2881 gttgcatact gttggcacag aaaggagcaa gggttaatga aacaagaaac ggagccggag
     2941 tctagtaggt tacattcgaa aaatgaagta gacatttggg tttgttgtga taagtatgtg
     3001 atctactgtc agggttctgt taacaatgcc tgagtcttac cttgatttca tcttcggtga
     3061 cagtgaagac atcatccaca aggtctctta taataggcca ggtattcaag ccaatgctgg
     3121 atttgacacc atctgctatg gtttctggag gatgaagatt gggggtcagt tctcctttca
     3181 gtttagactg gtagcagtca tctgcattcg agggctcagc agcgtatacc ttcacactag
     3241 gtttcagggc ctggggaagg aaggcacatg ttacaataca gcctttgtct acgtaaagga
     3301 ggcagagagt taaagatgtg ttacccttgg tgatcagaat ggaaacaaga ccttgaagca
     3361 ctttaataaa agttgtatct gataaaaaaa aaaaa
//
