LOCUS       NM_001085421            4040 bp    mRNA    linear   ROD 23-APR-2024
DEFINITION  Mus musculus testis-specific protein, Y-encoded-like 5 (Tspyl5),
            mRNA.
ACCESSION   NM_001085421 XM_139378 XM_910430
VERSION     NM_001085421.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4040)
  AUTHORS   Leng,X., Xie,S., Tao,D., Wang,Z., Shi,J., Yi,M., Tan,X., Zhang,X.,
            Liu,Y. and Yang,Y.
  TITLE     Mouse Tspyl5 promotes spermatogonia proliferation through enhancing
            Pcna-mediated DNA replication
  JOURNAL   Reprod Fertil Dev 36 (2024)
   PUBMED   38185096
  REMARK    GeneRIF: Mouse Tspyl5 promotes spermatogonia proliferation through
            enhancing Pcna-mediated DNA replication.
REFERENCE   2  (bases 1 to 4040)
  AUTHORS   Huang,C., Ruan,P., He,C. and Zhou,R.
  TITLE     TSPYL5 inhibits the tumorigenesis of colorectal cancer cells in
            vivo by triggering DNA damage
  JOURNAL   J Cancer Res Ther 19 (4), 898-903 (2023)
   PUBMED   37675714
  REMARK    GeneRIF: TSPYL5 inhibits the tumorigenesis of colorectal cancer
            cells in vivo by triggering DNA damage.
REFERENCE   3  (bases 1 to 4040)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY721490.1, BY715454.1, BC079547.1 and AC129208.4.
            
            On or before Jul 25, 2007 this sequence version replaced
            XM_910430.2, XM_139378.7.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                BY721490.1         2-38
            38-49               BY715454.1         4-15
            50-1031             BC079547.1         1-982
            1032-1032           AC129208.4         155396-155396
            1033-4040           BC079547.1         984-3991
FEATURES             Location/Qualifiers
     source          1..4040
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 13.91 cM"
     gene            1..4040
                     /gene="Tspyl5"
                     /gene_synonym="6330530B20; E130308C19Rik"
                     /note="testis-specific protein, Y-encoded-like 5"
                     /db_xref="GeneID:239364"
                     /db_xref="MGI:MGI:2442458"
     exon            1..4009
                     /gene="Tspyl5"
                     /gene_synonym="6330530B20; E130308C19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1307
                     /gene="Tspyl5"
                     /gene_synonym="6330530B20; E130308C19Rik"
                     /note="TSPY-like protein 5"
                     /codon_start=1
                     /product="testis-specific Y-encoded-like protein 5"
                     /protein_id="NP_001078890.1"
                     /db_xref="CCDS:CCDS49591.1"
                     /db_xref="GeneID:239364"
                     /db_xref="MGI:MGI:2442458"
                     /translation="MSGRSRGRKSSRAKGRGKGRARARVRAAAEDAWHDEKPPQSPRL
                     GEDSAAAQVQAGAAQGGAEPAELREEAACRLPLDCGLALRARAADERGLAAPDPDLER
                     ARSLAERLTSDTSFVGTVGALAKLRRGSRIGNRRVPGRKAPDTRSATGRGPQATVSGK
                     PKMASAGLCAAAPVGEEKKMTEKHAGAGSPATVGSMDTLETVQLKLETMNAQADRAYL
                     RLSRKFGQLRLHHLERRNLLIQSIPGFWGQAFQNHPQLSAFLNTKDKEVLSYLNRLEV
                     EELGLARLGYKIKFYFGRNPYFQNKVLIKEYGCGPSGQVVSRSAPIQWLPGHDLQSLS
                     KENPENNGSFFGWFSNHSSIESDKIVEIINEDLWPNPLQYYLISEEARGEKGKEERPG
                     PAKLSPAPAVRQPN"
     regulatory      3862..3867
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspyl5"
                     /gene_synonym="6330530B20; E130308C19Rik"
                     /note="hexamer: AATACA"
     polyA_site      3884
                     /gene="Tspyl5"
                     /gene_synonym="6330530B20; E130308C19Rik"
     regulatory      3986..3991
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspyl5"
                     /gene_synonym="6330530B20; E130308C19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      4009
                     /gene="Tspyl5"
                     /gene_synonym="6330530B20; E130308C19Rik"
                     /note="major polyA site"
ORIGIN      
        1 gtggtgacgt cacggttgcc atggagaggc cagcttcgta gagaccctgg gctggtagcg
       61 gctttgaaac cttgttctct ggcaccatga gcggacggag taggggtcga aagtcttccc
      121 gcgccaaagg ccggggcaaa ggccgggcca gagcccgggt ccgggccgct gcggaagacg
      181 cctggcacga cgaaaagcca ccacagagcc cgcggctcgg ggaggactcc gcggccgcgc
      241 aggtgcaggc cggcgcagct caaggaggcg ccgaaccagc cgagctgcgg gaagaggcgg
      301 cctgccgcct cccgctggac tgcggcctgg cgttgcgggc tcgggctgca gacgagcgcg
      361 ggctggcggc ccctgatccg gacctggaga gggcccgttc cctcgccgag cgcctgacca
      421 gcgacaccag cttcgtggga accgtgggag ccttggcgaa gctgcgacgc ggctcccgca
      481 ttggaaatcg gcgagtcccc gggaggaagg ccccagatac tcggagcgcc acggggaggg
      541 gacctcaggc cacagttagt gggaagccga agatggcctc tgcggggttg tgcgccgctg
      601 ctccagtggg ggaggaaaaa aagatgacag agaagcatgc tggggcaggg tctcccgcga
      661 cagtgggcag catggatacc ctagagacgg tccagctaaa gctagagacc atgaatgcac
      721 aggctgacag ggcatatctc aggctttcac gcaagtttgg ccagttgcga cttcaccact
      781 tagagcgccg gaacctcctc atccagagca ttccgggctt ctgggggcaa gcttttcaga
      841 accatcccca gctgtcagct tttctgaata ccaaagataa ggaggtattg agctatttga
      901 acagactgga ggtggaagaa cttggccttg ccaggttggg ctacaaaatc aagttctact
      961 ttggccgaaa cccctatttc caaaacaagg tgctcattaa ggaatatggc tgtggtccat
     1021 ccggtcaagt ggtgtctcgt tcagctccaa tccagtggct cccaggccat gatctacaat
     1081 ccctaagcaa ggaaaaccca gaaaacaatg gtagcttctt tgggtggttt tcaaatcaca
     1141 gctctattga gtctgacaag attgttgaga taattaatga ggacctgtgg cccaatcctc
     1201 tacagtacta cctgatcagt gaagaagccc gtggagagaa aggaaaggaa gaaaggccag
     1261 gtccagcaaa actgagccct gcacctgcag tgaggcagcc caactgatcc gacacagatc
     1321 tccctaccac ctcttgctgg acctgttagg ctgaccacgt gggtttggtt gtctgccttc
     1381 tgttcatacc atacatggta gccactttgg acttatcttc aagaatgtga catttgtgat
     1441 aatattctct gcttccccat gacctcacct tgtcacaata gtgttgcatg tgtgacattc
     1501 tcactgtttg tgtatcaatc acttctgata tatgactttc tctacactat ccagtccctg
     1561 ttcttggctc tggctcttcc cactttcctt tcacctggac attctgagtc attgtccaga
     1621 tggatattca agctatgcta cttcatggcc agtcagctgg gctttgtgtc cattttaagc
     1681 atgcatgtta tcagtggcaa gatttttcta ttgctatcac aaaatgaagc cagtgctttt
     1741 attctgtggg tatggagaca tcaaccaagg ttcttcctat tttgtttccc acttcagcct
     1801 aggtccagca gactactggt gtggatgagg acaagggaaa acaagaatat gttctgttca
     1861 catcatacat ctcttcttgc ctcatagaca gcctgctagt gaaccctcat catggtctgg
     1921 ctatgcctga ctgcagtcag tccattgact gttggctagg tgggtgttat tggctccatc
     1981 ttgcttatca aagacctcaa gaactgccta tggacccagg taccttccca atgcatgagc
     2041 tacaaaccca ccttccccag actttagaaa acctactgct tgtcagattg gtgggcagcc
     2101 tggcatttgt gaacatatgc ttgttgctct catgttgtga gccctgagaa gggtagagct
     2161 ttggaccaca tctttatcaa ctgggtatct gtgccatttc tcttattcct tattccttgc
     2221 taagaaggga caagaaggaa ttttgaggaa gagagatttt tcatttctat gcccatgttt
     2281 acgtcacacc ttcatgcaac ttagtctcct tccctatcaa cctaccttgg gacttcctac
     2341 tctccttatg aaccctctcc cagcctttta aaatagcatc acagtgcaga caaaaaaaaa
     2401 atcatcaacc agacttttct acatacagtt agggaggcag aaagaggctt cctttgcaca
     2461 ctcatgtagt aggctgagat aggataaaga aaaaccaaaa ggtctcaaga gagtctatgg
     2521 tcagacatag gtcctgaatc ctggctttgt tcagtagttc taaagttgta tgcatctgct
     2581 agaattagaa accctaaggc agcagtgttg tggtctcttg tgtcttctgt ctgtttcttt
     2641 ttaagtccca ggggcttctt ccttttgtct catttgatag cctatgccac tggggtcccc
     2701 agcccccagc tttcccactc agtagtgctt tgctatcttt gtttcttagc ccaaatgtac
     2761 tcactatgga agaatcccaa ggtgttactg gggacaggac aggcagaacc tgttctagat
     2821 atttctggta agtgtgcagg ctgagctgga ccatctctac caaagtttgt ctgtgttctg
     2881 acttatcttc tttggaaagt agaactctgt aagccagccc ccatgctggt atggaagact
     2941 tcattcttac ctttgtgagg gggtccttga gaaaataggc aagggaatca gggcaagata
     3001 ggtatgaacc tggtattgag tgggtcagta aaacttgata gaaatgcatt gtgatgctgc
     3061 agagatagtt atcctatctc ttagtgatga aggtgacaga agagacctta ctcagggttg
     3121 ggatgggaga gttaaaggtg tatgtaaaca agatgccagg tcaaggatgg attcagagtt
     3181 ctgggcagtc ttcatcatcg ttagttaatt tctttttttt tttttttttt ttgtaattac
     3241 agaaacaaac caaaagtaat gttactatat tgggtagaag ttacatccta aagtgtgtaa
     3301 gattatgcta aatgctgagt atttgtcctc taaaatctta ccacattttg tatttttgtc
     3361 taatgaggaa aacagagctg tataagtttg cttttgctat ttattatgta aatttccaaa
     3421 aaataagagt gaagaaagtg gtgcctggac cctgtgtacc ttgtagctag aagcaatgag
     3481 taacctaatg tcatctgtat cttcttcctc ctgcattttt cgtgaaagtc caagtgcata
     3541 taccagtgca gctggatcta ctttgggaga ctggggcatt gagctgaaat gtgcactctc
     3601 atgatcacaa taactccact aatgtgaatt ttgtgtgaac tgatgatatt tttagaagtg
     3661 ggactcataa atgagtcttc acaattagtg gaactcaaaa gagcattggt gaggatattc
     3721 tgccacagat acaaaagaag agaccattat gttgtaaatc tgcctatgac cctgatgtaa
     3781 ggcacttgag acccttttct cctttgtaac atagagactt gtatggactg ttagggttgc
     3841 tgtgttctgt gaaaataatc aaatacaaca taatcttttc attagtttct gtagttgata
     3901 atttgatatc ctggtaataa tgtgattatt tccctgttcc taagtggcat aaatacttgc
     3961 aagtgtgcat gtacaatgga aaaaaaataa aaaaaatatt cttgtgtcaa aaaaaaaaaa
     4021 aaaaaaaaaa aaaaaaaaaa
//
