LOCUS       NM_001316748            2521 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus tetraspanin 14 (Tspan14), transcript variant 2, mRNA.
ACCESSION   NM_001316748 XM_006519262
VERSION     NM_001316748.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2521)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2521)
  AUTHORS   Haining,E.J., Yang,J., Bailey,R.L., Khan,K., Collier,R., Tsai,S.,
            Watson,S.P., Frampton,J., Garcia,P. and Tomlinson,M.G.
  TITLE     The TspanC8 subgroup of tetraspanins interacts with A disintegrin
            and metalloprotease 10 (ADAM10) and regulates its maturation and
            cell surface expression
  JOURNAL   J Biol Chem 287 (47), 39753-39765 (2012)
   PUBMED   23035126
REFERENCE   3  (bases 1 to 2521)
  AUTHORS   Garcia-Espana,A., Chung,P.J., Sarkar,I.N., Stiner,E., Sun,T.T. and
            Desalle,R.
  TITLE     Appearance of new tetraspanin genes during vertebrate evolution
  JOURNAL   Genomics 91 (4), 326-334 (2008)
   PUBMED   18291621
REFERENCE   4  (bases 1 to 2521)
  AUTHORS   Roma,G., Cobellis,G., Claudiani,P., Maione,F., Cruz,P., Tripoli,G.,
            Sardiello,M., Peluso,I. and Stupka,E.
  TITLE     A novel view of the transcriptome revealed from gene trapping in
            mouse embryonic stem cells
  JOURNAL   Genome Res 17 (7), 1051-1060 (2007)
   PUBMED   17540781
REFERENCE   5  (bases 1 to 2521)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   6  (bases 1 to 2521)
  AUTHORS   Mu,X., Zhao,S., Pershad,R., Hsieh,T.F., Scarpa,A., Wang,S.W.,
            White,R.A., Beremand,P.D., Thomas,T.L., Gan,L. and Klein,W.H.
  TITLE     Gene expression in the developing mouse retina by EST sequencing
            and microarray analysis
  JOURNAL   Nucleic Acids Res 29 (24), 4983-4993 (2001)
   PUBMED   11812828
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC108430.11, AK030593.1 and BG807867.1.
            
            On Oct 24, 2015 this sequence version replaced XM_006519262.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK156671.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                AC108430.11        2805-2847
            44-2237             AK030593.1         35-2228
            2238-2521           BG807867.1         281-564
FEATURES             Location/Qualifiers
     source          1..2521
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 22.36 cM"
     gene            1..2521
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /note="tetraspanin 14"
                     /db_xref="GeneID:52588"
                     /db_xref="MGI:MGI:1196325"
     exon            1..43
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     exon            44..141
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     exon            142..192
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     exon            193..339
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     exon            340..510
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     exon            511..636
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     exon            637..681
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     exon            682..801
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     exon            802..2504
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2395..2400
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /note="hexamer: AATATA"
     polyA_site      2412
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /note="major polyA site"
     regulatory      2464..2469
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /note="hexamer: ATTAAA"
     regulatory      2469..2474
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
                     /note="hexamer: AACAAA"
     polyA_site      2484
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
     polyA_site      2504
                     /gene="Tspan14"
                     /gene_synonym="D14Ertd226e; Tm4sf14; tspan-14"
ORIGIN      
        1 gtgggaggag tgaagaacag ctctcgaaga tgtctcagcc tgggtcctcc ttctcagaag
       61 atgcactatt atagatactc gaacgccgag gtcagctgct ggtacaagta cctgctcttc
      121 agctacaata tcgtcttttg gctggctgga gttgtcttcc ttggagtcgg gctgtgggca
      181 tggagcgaaa agggtgtgct gtccgacctc accaaggtga cccggttgca tggaatcgac
      241 cccgtcgtgc tggtcttgat ggtgggcgtg gtgatgttca cactgggatt cgcaggctgt
      301 gtcggggccc tccgagagaa catctgcctg ctcaagtttt tctgtggggc cattgtgctc
      361 atcttcttcc tggaactggc cgtggccgtg ttggcctttt tattccaaga ctgggtgaga
      421 gaccggttcc gggaattctt cgagagcaac atcaagtcct atcgggatga catcgacctg
      481 cagaacctca ttgactccct tcagaaagct aatcagtgct gcggggctta cggccctgaa
      541 gactgggacc tcaatgtcta cttcaactgc agtggtgcca gctacagccg agagaaatgt
      601 ggggtaccct tctcctgctg tgtgccagat cctgcacaaa aagtcgtgaa cacacagtgt
      661 ggctatgatg tccggattca gctgaagagc aagtgggatg agttcatctt tacaaaagga
      721 tgcatccagg ctctggaagg ctggctgccc aggaacatct acattgtggc tggtgtcttc
      781 attgccatct cactgctgca gatttttggc atcttcctgg cgaggaccct gatctcagac
      841 atcgaggcag tgaaggcagg ccatcacttc tgagaagcag atgcagcaaa tggagttgag
      901 ccacatgtag aggtcaagcc tttcactgtc cagcagcagc agcagaagtc gacattagcc
      961 acccacaacc agaccccagt cttcggcatc agtgtgatat gacctctcag tttcttcttg
     1021 ctggtgctga agaccaaggc cccttctcat ctgcccacac ttgacatggc atctctgaaa
     1081 agggcttgcc cagagacaga gaatgtgttt ttatgtggag tagtaactct gaggacagat
     1141 ggctcccatg gctgcaggaa aggcttgatg gcccttatgg agcccaagag catctgcagg
     1201 cctctgcctc ctcagtaagg cttaggtaga tgctcagctc atatcttctg tgggtatagc
     1261 atcagtatgg gaccagcact gaggacaagg cttctggttc catctgatca agaaggagga
     1321 ggagggatga gtggtctagt ggtaccctcg tgccaacagg gttcgtggtg gtgcaaacat
     1381 gccaggggtt tgcagaatcc tcagccatgt ccaagtgaat tatgcctgag ccagccatag
     1441 ccggtcctgg ggagcacatc accactgcct tccaagccta cactgctctc ccagggtaga
     1501 acagcctcgt ttctccatag cattaagccc tactgagggc cagctctcct gttcttatag
     1561 tgtgtaaata gtttatttat aggggtaaga gtgttccttc accatatctt catagcctct
     1621 tccgtctggc attcttttct cagcagcctt acccagtgtc tgggaccaag ctgtcctttt
     1681 cagttccccg agtgtcttaa gaaccagctg tgacagcttc tccctctggt tcacatcccc
     1741 tccatgcgcc cctgcttggc ttccctgtct tctggtctcg gtgctactga aatggccacc
     1801 agaacttgaa tcctgactga ccctttctcc ttccccgctg ccctccaggg agccccagct
     1861 cctgattgcc agctggaaac tgggttcctc tcacgaccac atacagctag tggcccaaag
     1921 tatgctgtcc ctggagggca acgctcctgc agccaggccc tggcaagcac agacagctgg
     1981 tgctgtgtgg aatgctcagt gcatcttatc tctaacttcc gtggtgactc ccccacccac
     2041 atgccgtgtt cactgtcagc actgttctga ggctgctctt gaaaatgatg tctgtcttac
     2101 gtactggata ctccgaggca tgctggcgtc tgtccacctg gggctgggct actctctagt
     2161 gcttctttat aacttgtatc tgtccttacc gttcagggat tgagtactac cttcagttac
     2221 ttgccgaagt gtacattcta gtgtggtgta tactggtgat actggtgggg gtgtgttcat
     2281 gatgatgatg atgttataat tttctaaata attctctata gactagagga agaagaatgc
     2341 ttgtgttttt aggaagtgtg cagcttctct ttgacctgcc aaactctttt atggaatata
     2401 tctttatatt aatgctgttg tttgggtctt tttttttttt ttcctttctg gtttgcaatc
     2461 actattaaaa caaaaaagca ttaagcattt tggtgataaa ttgaaaaaaa aaaaaaaaaa
     2521 a
//
