LOCUS       NM_026743               4209 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus tetraspanin 11 (Tspan11), mRNA.
ACCESSION   NM_026743
VERSION     NM_026743.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4209)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4209)
  AUTHORS   Nakanishi,Y., Matsugaki,A., Kawahara,K., Ninomiya,T., Sawada,H. and
            Nakano,T.
  TITLE     Unique arrangement of bone matrix orthogonal to osteoblast
            alignment controlled by Tspan11-mediated focal adhesion assembly
  JOURNAL   Biomaterials 209, 103-110 (2019)
   PUBMED   31030082
  REMARK    GeneRIF: Unique arrangement of bone matrix orthogonal to osteoblast
            alignment controlled by Tspan11-mediated focal adhesion assembly.
REFERENCE   3  (bases 1 to 4209)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 4209)
  AUTHORS   Garcia-Espana,A., Chung,P.J., Sarkar,I.N., Stiner,E., Sun,T.T. and
            Desalle,R.
  TITLE     Appearance of new tetraspanin genes during vertebrate evolution
  JOURNAL   Genomics 91 (4), 326-334 (2008)
   PUBMED   18291621
REFERENCE   5  (bases 1 to 4209)
  AUTHORS   Hemler,M.E.
  TITLE     Specific tetraspanin functions
  JOURNAL   J Cell Biol 155 (7), 1103-1107 (2001)
   PUBMED   11756464
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC145568.4.
            
            On Mar 21, 2007 this sequence version replaced NM_026743.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK090022.1, AK028808.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-257               AC145568.4         131356-131612
            258-352             AC145568.4         156684-156778
            353-544             AC145568.4         167286-167477
            545-619             AC145568.4         181935-182009
            620-724             AC145568.4         182828-182932
            725-883             AC145568.4         186951-187109
            884-970             AC145568.4         187441-187527
            971-4209            AC145568.4         193527-196765
FEATURES             Location/Qualifiers
     source          1..4209
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 62.56 cM"
     gene            1..4209
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /note="tetraspanin 11"
                     /db_xref="GeneID:68498"
                     /db_xref="MGI:MGI:1915748"
     exon            1..257
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            258..352
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             269..1030
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /note="tspan-11"
                     /codon_start=1
                     /product="tetraspanin-11"
                     /protein_id="NP_081019.1"
                     /db_xref="CCDS:CCDS20567.1"
                     /db_xref="GeneID:68498"
                     /db_xref="MGI:MGI:1915748"
                     /translation="MAHCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVE
                     KSGYLSILASSTFAASAYILIFVGGLVMTTGFLGFGAIIREQKSCLSTYFCLLLVIFL
                     VELVAGVLAHVYYQRLSDELKWHLNSTLTEHYGQPRAAEITASVDRLQQDFKCCGSNS
                     SADWQHSAYILSQEALGRQVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFVAD
                     HLLLMGAVGIGVACLQICGMVLTCCLHRRLQQQFY"
     exon            353..544
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            545..619
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            620..724
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            725..883
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            884..970
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            971..4209
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1363..1368
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /note="hexamer: AATAGA"
     polyA_site      1399
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /note="major polyA site"
     regulatory      2021..2026
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2054
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
     regulatory      2160..2165
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /note="hexamer: AACAAA"
     polyA_site      2183
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
     regulatory      3467..3472
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
                     /note="hexamer: AAGAAA"
     polyA_site      3493
                     /gene="Tspan11"
                     /gene_synonym="1110014F12Rik"
ORIGIN      
        1 caggaccgag tgctcagtgt gctctgcttt gggtgggaaa aaaaaaaagc cagctccaaa
       61 caaagagcag ccccggtccc gcccgccccg ggcctgtggg cgcgtccccc agtctgagtg
      121 agaggggcag ccagcagcca ccgcgggcca gtgggcaagg agcgcagggt ggagcgggcg
      181 gctgtggcca ggacagccac aatcacagct ccggattccc gatccctcgc tgcatccagc
      241 ctggcggttt tggccgggtc cagccgccat ggcgcactgc aagacagagc aggatgactg
      301 gctgctggcc cacctgaagt acctgctctt catcttcaac ttcttcttct gggtaggtgg
      361 ggcagccgtc atggccgtgg gtatctggac actggtggag aagagcggtt acctcagcat
      421 cttggcctcc agcacgttcg ctgcctctgc ctacatcctc attttcgttg gtggtcttgt
      481 catgacaact ggcttcctgg gctttggggc catcatccgg gagcagaaga gctgcctctc
      541 cacatatttc tgcctgctgc tggtcatctt ccttgtggag ctggtggcag gggtcctggc
      601 acatgtgtac taccagaggc tgagtgacga gctgaagtgg cacctgaaca gcaccctgac
      661 tgagcactac ggacagccca gggccgcaga gatcacagcc tcggtggacc ggctgcagca
      721 ggacttcaaa tgctgtggca gtaacagctc agccgactgg cagcacagcg cgtacatctt
      781 gtctcaggaa gccctgggtc gccaggtgcc cgacagctgc tgcaagacag tggtggcccg
      841 ctgtggtcag cgagcccacc cctccaacat ctacaaggta gagggaggct gtatggccaa
      901 gctggaacag ttcgtggctg accacctgct gctcatggga gcggtgggta ttggggtagc
      961 ctgtcttcag atctgtggga tggtcctcac ctgctgcttg caccgaaggc tccagcaaca
     1021 attttattaa aggacaccca tgtaccctgc tgactggccc acccaaggga ccacatctcc
     1081 acttcctgaa ccaggcctgc aaagtcatcg ctggggctgt ggactcgctc caccctatgc
     1141 agaggccacc aaatgtctgt ggttgtggtt cctgtgcatc ccgactggca ggggcctcag
     1201 ctaactcctc cattcctaag tactcagcca ctgccaaaat ccttgccaag ggatgatcct
     1261 ggccagaggc agccagagcc ctttgccagg cactgggacg ctgtggacta caggggggcc
     1321 agagctcatc tccctctgat ccatctcagt gtctgagtct ggaatagaag gccgtcggat
     1381 ggtccctctg agagtcctat agggcttggc gtgtgattcc cactggcatg tggccccagg
     1441 ctggctctcc tttgggaaaa ccagcacttt gggcagacca ggttagctca gccttttcca
     1501 aaacctggct ggtttttcaa tctctccaca gaatagctgg ccaagacctt cctgtaaggt
     1561 atagggcaga agtgatcaaa ggtggggcat cttaaggtag ctgttgaagc caacagcaca
     1621 gggcactaag gaagcaggtt ggtcacaaca cctaggaaag tcacacgatg gtcacaatcc
     1681 ccagcctctg gtcctgttcc caggcttgac ttccaaaatg tcaggcttaa aatgttagtg
     1741 aatgtaaaac tatctcctcg accaggtggg gggcacacca cagtctcagc tgctgaggag
     1801 aggatgcgac gctacgggga aggaggaact ctgcctgcac cccatctcct ggtgcccttg
     1861 tgacctcact gtttctcttc catgcattct ccacttcctt gtccactgtg ctggagtaga
     1921 tgccggccct tccttcgctc ctctctttag tcacggaatg acacaggaga ttcaaggaga
     1981 actcatgtgt taaaagacac ggaaagaaaa ttctagaaaa attaaaggtt gatagtaggt
     2041 atcatagaca accataggga cccccctgtg attattatta ctgtaggcag ctttgcacac
     2101 cagggctcca ctcctagctt cagtcttccc tgcttgggtc ctgctcatct ctctacaata
     2161 acaaacctca gttccgacat gaaccagcag cagcagcaaa aagtgtccaa ctggttgtct
     2221 acctggctca gttctcactg tggtgacccc agatcctgct gatctgggtc aattgttgga
     2281 gagagatgag ctcccaccca cacatgggtg gactaagggc cactggttgc agtcaccagc
     2341 acaggtggaa ttccactctc agggcaggaa gtagctgtgt gcacagaggg aacatcaggc
     2401 tctcaggtca gacagcctcc tacacactgg cgttctccag gggctactcg gagcctggac
     2461 tggcttatat tattcacctg aaggaccaac actaagaaga agacactcac tccccaaaat
     2521 cccagactac actacatatg gctcagagaa aaacctcagc ttcctccacc ttcccaggat
     2581 tcacgcagat actcagactg gctgtggttc cgaagcttgt agatggagga tggagaagaa
     2641 aagtggtggg gcccaggtaa tgttctcccc aaaaaggcac tgagggaggt gatagtgtgc
     2701 aaaggaatac tgtggcctca ggcatctgct ttggtaggct catcagggag atgaggtcag
     2761 aggtgataag cagccactgt tggtacagac ttgatgcaga ggtagtccag gagagcatga
     2821 ggcatccact cagtcagagc cacagagtga gcagacagcc ccaaatgtga ctaccttgac
     2881 catacatcag ccttggtgac aagatggggt gagaggacat gaagcacata gtaggccagg
     2941 ttcgttccag cagcttcgaa ggctggagcc aagtctgtag tgaggtgtcc ccaacagttt
     3001 catgccagag tatttctacc tatttcccac tcagggacgg ggccctgttc cgaggttatc
     3061 ggtctggatt tcttagagaa agggaaggac acacctgtag aatgtcaccc tcagtcctgg
     3121 gtcagcacaa aacatactgg ggtcccatgc caggccctga acttggtgta gctcaagcca
     3181 gtggaccctc attctaagca tataagtgag ccaccattcc ctaaactcaa agtggccacc
     3241 tcaaaaacac agcccacccc taaatccccc agtgaccagt attggggaac aaggatggac
     3301 cttagtctat gacatcagat ggggtgtctc catgcattcg tccctttccc tccccaacag
     3361 tgcatcccca ccctcacccc atagcaccat tggcatgtat atattcttca ctatgctatt
     3421 catagtgaca ccaacgggat gtgctatagt ccccattctg ttgatgaaga aactaaggct
     3481 tggacaagct ggacatcagt ggtgattgct gttgccatgg ccccagtcag gtggacctaa
     3541 agaaatcttg tctgggtgcc tctcctcccc agcaccagct gccacagctg ccagggaggt
     3601 attcaggagc agagtgtcct acgtggtgtg gccaagtagt ggcagccttg acacctccca
     3661 ggttggatgg gagcatcctg catggccgat cccaacagct ttctgttaaa gcagacacct
     3721 gtctcatttc ggaacgacaa ccaggtcctc tggagcagct aagaaggcca gggctcatag
     3781 gaatggcccg gagcacactc tggggtcctt cagagccatg atagtgagaa cagggactgt
     3841 cttagagatc actctccata aagatgggag tcacaccatg tggggatcac actgtatcca
     3901 ctcagagtca cccaggtatg gaggcgccct ggatgctgat gctgagactc ccctcaggcc
     3961 aggctctcct ctaccttctt gcccagctcc caagctccta ttctgattat ttgttgtttc
     4021 tgagtggaca caaggtgact tttgtcctga gtgccttcac ccttcacatg gccatagggg
     4081 ctcagctcct aaagatgccg gatgtggggg tatgcacagc aggccagtgt gatgagccac
     4141 tttgaactca gaatctgcct ctctggacag cttccaaggt tttgaataaa tggatcagtg
     4201 agaacctgc
//
