LOCUS       NM_001081300            5717 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus teashirt zinc finger family member 1 (Tshz1),
            transcript variant 1, mRNA.
ACCESSION   NM_001081300 XM_888252
VERSION     NM_001081300.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5717)
  AUTHORS   Kc,R., Lopez de Boer,R., Lin,M., Vagnozzi,A.N., Jeannotte,L. and
            Philippidou,P.
  TITLE     Multimodal Hox5 activity generates motor neuron diversity
  JOURNAL   Commun Biol 7 (1), 1166 (2024)
   PUBMED   39289460
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5717)
  AUTHORS   Alderman,P.J., Saxon,D., Torrijos-Saiz,L.I., Sharief,M., Page,C.E.,
            Baroudi,J.K., Biagiotti,S.W., Butyrkin,V.A., Melamed,A., Kuo,C.T.,
            Vicini,S., Garcia-Verdugo,J.M., Herranz-Perez,V., Corbin,J.G. and
            Sorrells,S.F.
  TITLE     Delayed maturation and migration of excitatory neurons in the
            juvenile mouse paralaminar amygdala
  JOURNAL   Neuron 112 (4), 574-592 (2024)
   PUBMED   38086370
REFERENCE   3  (bases 1 to 5717)
  AUTHORS   Catela,C., Chen,Y., Weng,Y., Wen,K. and Kratsios,P.
  TITLE     Control of spinal motor neuron terminal differentiation through
            sustained Hoxc8 gene activity
  JOURNAL   Elife 11, e70766 (2022)
   PUBMED   35315772
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5717)
  AUTHORS   Ypsilanti,A.R., Pattabiraman,K., Catta-Preta,R., Golonzhka,O.,
            Lindtner,S., Tang,K., Jones,I.R., Abnousi,A., Juric,I., Hu,M.,
            Shen,Y., Dickel,D.E., Visel,A., Pennachio,L.A., Hawrylycz,M.,
            Thompson,C.L., Zeng,H., Barozzi,I., Nord,A.S. and Rubenstein,J.L.
  TITLE     Transcriptional network orchestrating regional patterning of
            cortical progenitors
  JOURNAL   Proc Natl Acad Sci U S A 118 (51) (2021)
   PUBMED   34921112
REFERENCE   5  (bases 1 to 5717)
  AUTHORS   Wen,Y., Su,Z., Wang,Z., Yang,L., Liu,G., Shang,Z., Duan,Y., Du,H.,
            Li,Z., You,Y., Li,X., Yang,Z. and Zhang,Z.
  TITLE     Transcription Factor VAX1 Regulates the Regional Specification of
            the Subpallium Through Repressing Gsx2
  JOURNAL   Mol Neurobiol 58 (8), 3729-3744 (2021)
   PUBMED   33821423
REFERENCE   6  (bases 1 to 5717)
  AUTHORS   Manfroid,I., Caubit,X., Kerridge,S. and Fasano,L.
  TITLE     Three putative murine Teashirt orthologues specify trunk structures
            in Drosophila in the same way as the Drosophila teashirt gene
  JOURNAL   Development 131 (5), 1065-1073 (2004)
   PUBMED   14973285
  REMARK    GeneRIF: three mouse Tsh genes are functionally equivalent to the
            Drosophila tsh gene when expressed in developing Drosophila embryos
REFERENCE   7  (bases 1 to 5717)
  AUTHORS   Aubert,J., Dunstan,H., Chambers,I. and Smith,A.
  TITLE     Functional gene screening in embryonic stem cells implicates Wnt
            antagonism in neural differentiation
  JOURNAL   Nat Biotechnol 20 (12), 1240-1245 (2002)
   PUBMED   12447396
REFERENCE   8  (bases 1 to 5717)
  AUTHORS   Long,Q., Park,B.K. and Ekker,M.
  TITLE     Expression and regulation of mouse Mtsh1 during limb and branchial
            arch development
  JOURNAL   Dev Dyn 222 (2), 308-312 (2001)
   PUBMED   11668608
REFERENCE   9  (bases 1 to 5717)
  AUTHORS   Caubit,X., Core,N., Boned,A., Kerridge,S., Djabali,M. and Fasano,L.
  TITLE     Vertebrate orthologues of the Drosophila region-specific patterning
            gene teashirt
  JOURNAL   Mech Dev 91 (1-2), 445-448 (2000)
   PUBMED   10704881
REFERENCE   10 (bases 1 to 5717)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124012.4.
            
            On Jul 20, 2018 this sequence version replaced NM_001081300.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK220545.1, SRR7652917.193691.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1102              AC124012.4         99649-100750
            1103-5717           AC124012.4         169873-174487
FEATURES             Location/Qualifiers
     source          1..5717
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 57.53 cM"
     gene            1..5717
                     /gene="Tshz1"
                     /gene_synonym="5730407I04Rik; D18Bwg1409e; Mtsh1;
                     NY-CO-33; Sdccag33; teashirt1; Tsh1"
                     /note="teashirt zinc finger family member 1"
                     /db_xref="GeneID:110796"
                     /db_xref="MGI:MGI:1346031"
     exon            1..1102
                     /gene="Tshz1"
                     /gene_synonym="5730407I04Rik; D18Bwg1409e; Mtsh1;
                     NY-CO-33; Sdccag33; teashirt1; Tsh1"
                     /inference="alignment:Splign:2.1.0"
     CDS             1063..4317
                     /gene="Tshz1"
                     /gene_synonym="5730407I04Rik; D18Bwg1409e; Mtsh1;
                     NY-CO-33; Sdccag33; teashirt1; Tsh1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     teashirt homolog 1; serologically defined colon cancer
                     antigen 3 homolog; serologically defined colon cancer
                     antigen 33"
                     /codon_start=1
                     /product="teashirt homolog 1 isoform 1"
                     /protein_id="NP_001074769.1"
                     /db_xref="CCDS:CCDS37876.1"
                     /db_xref="GeneID:110796"
                     /db_xref="MGI:MGI:1346031"
                     /translation="MPRRKQQAPRRSAAYVPEEELKAAEIDEEHAEDGGLSLDIQESE
                     FACNEETEIKEAQSYQNSPVSTATNQDAGYGSPFSEGSDQLAHFKSSSSREEKEESQC
                     PDSVSYPQDSLAQIKAVYANLFSESCWSSLALDLKKSNSATSNNDASQKESSTPTPTP
                     PTSTASTACTTATTAITSCSTSTSHSSTTSNSSSSGYDWHQAALAKTLQQTSSYGLLP
                     EPSLFSTVQLYRQNNKLYGSVFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNR
                     DKDSEKTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQK
                     VPLKEPVPAITKLVPSTKKRALQDLASPCSPEPTGVATEVALSESAKDQKTANPYVTP
                     NNRYGYQNGASYTWQFEARKAQILKCMECGSSHDTLQQLTAHMMVTGHFLKVTTSASK
                     KGKQLVLDPVVEEKIQSIPLPPTTHTRLPASSIKKQPDSPAGSVASEEKKEPEKEKEK
                     EKAPPAAGDAERKIKEETEDATEKFEPTALYQYLREEDLDDSPKGGVDILKSLENTVS
                     TAISKAQNGAPSWGGYPSIHAAYQLPGTVKPLQSAVQSVQIQPSYASSVKSLSSTEHN
                     ALLHSPGSLTPPPHKSNVSAMEELVEKVTGKVSIKKEERPTEKEKSSPVKAISPVAKE
                     NKDLPKTEETGSKPQKKGSDSETGKAKKESTLDAHTPNGTEPLKAKVTNGCGHLGIIT
                     DHSPEPSFINPLSALQSIMNTHLGKVSKPVSPSLDPLAMLYKISNSMLDKPVYPTTPA
                     KQADAIDRYYYENSDQPIDLTKSKNKPLVSGVADAVSSPLRESALMDISDMVKNLTGR
                     LTPKSSTPSTVSEKSDADGSSFEEALDELSPVHKRKGRQSNWNPQHLLILQAQFASSL
                     RETAEGKYIMSDLGPQERVHISKFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTG
                     HPVFFCNDCASQFRTASTYVSHLETHLGFSLKDLSKLPLSQIQEQQSVVSKALTNKTL
                     GPLGSSEEDLGSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLIYVTELEKQ"
     exon            1103..5717
                     /gene="Tshz1"
                     /gene_synonym="5730407I04Rik; D18Bwg1409e; Mtsh1;
                     NY-CO-33; Sdccag33; teashirt1; Tsh1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5684..5689
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tshz1"
                     /gene_synonym="5730407I04Rik; D18Bwg1409e; Mtsh1;
                     NY-CO-33; Sdccag33; teashirt1; Tsh1"
                     /note="hexamer: AATAAA"
     polyA_site      5713
                     /gene="Tshz1"
                     /gene_synonym="5730407I04Rik; D18Bwg1409e; Mtsh1;
                     NY-CO-33; Sdccag33; teashirt1; Tsh1"
                     /note="major polyA site"
ORIGIN      
        1 agttgagact gtctgaaagc tctgcgatcc gaatgtgtgt tatatttcac tgaaaagagg
       61 agagagggag agcgcatctc ctctctccca ggagtttggg ggggacagta cacgctcatc
      121 tcgcccaccc agtgaatgtc cgttcttcac cccctcggtg cccactctcc gggttgttgt
      181 tggctttttt tttttttttt ggagggtgtg tgtggggttt ttttgtgtgt gtgtttttcg
      241 aatttttttt ctcttggaag atcaagaccg gccaaaaaat ccacgatcaa aatgtgtttg
      301 cattagattt ctcctcggaa gaagcggcga tcctggcggc caaggccccc cgggggcagc
      361 gcggggcacg aagtggcgct ccggcgggtg acactgtttg atctgtgact gtttggaagg
      421 tggagcggcg ctgacatctc ccccggcgca tgtatgtaca ggggcttcac tcctgtcttg
      481 tttgctttct tcctcctaga ctaagtgcgg ggaggaaagg acagccggtc ggcctcgctg
      541 gcgcacaatg agagagctgc gacccgcgca ctagcagcgc ccgccgcgac ccccaccgcc
      601 agcagagagg ggccgagaaa gttgcgcgcg gagactcgcg gctcgcccag gaaggcgcgg
      661 gagcgcccgg cggcgcccgg acagcgcccg cccatcacag cgccagcggc atggagcgcg
      721 ggccgcgggc cggccttccg agcgcccgcc gctgcgcccg cggcccgcgc cggggatgac
      781 tccgggctcg gcgcccaggc cccgcgcgct ccgcccgcag cccggcggcc cgggagcggc
      841 ccgtgcggcc gccgccgccg ccagctgagc ggcccgggcg cggcggtcca tgcgagcggc
      901 gcccgccatc cgcggcgcgc ccggagcccg gagcccgcgg ggacgaggcc aaagttgggc
      961 gcgccgcgga gttgcgcccg cgcccgggcc ccgcgtcccc gctccccgcg ccccgcgaac
     1021 tccggcggcg gctgaggcga cggctgcggc ggcccgagca gcatgccgag gaggaagcag
     1081 caggcccccc ggcgctcggc agcttacgtt cccgaggaag aactgaaggc agccgaaata
     1141 gatgaggagc acgcggagga tggtgggctg tctctggaca ttcaggagag cgaatttgcg
     1201 tgcaatgaag agacagagat caaagaagcc cagagctatc agaactcccc tgtcagcact
     1261 gccaccaatc aagacgctgg ctacggatcg cccttcagtg agggcagtga ccagctggcc
     1321 catttcaaaa gctcctcctc cagagaagag aaggaggagt cgcagtgtcc agacagtgtc
     1381 tcctaccccc aggacagctt ggcacagatc aaagccgtgt atgcgaactt attctcagag
     1441 tcctgctggt ctagcctagc attggattta aaaaagtcca attctgccac cagcaacaac
     1501 gatgccagcc agaaggagag ttccacacct acccccacgc ctcctactag taccgccagc
     1561 accgcctgta ccacggccac cacggccatc accagctgca gcaccagcac cagccatagc
     1621 agcaccacca gtaacagcag cagctcgggg tatgactggc accaggccgc cctggccaag
     1681 acgctgcagc agacgtcgtc ctacggactg ctgcctgagc ccagcctgtt cagcaccgtg
     1741 cagctctacc gacagaataa caagctgtat ggctccgtgt tcacgggggc cagcaagttc
     1801 aggtgcaaag actgcagcgc ggcctacgac acgctggtgg aactgacggt gcacatgaac
     1861 gagacaggcc actatcgaga tgacaacaga gacaaggact ccgagaagac caagcggtgg
     1921 tccaagccca ggaagcgttc cctgatggag atggagggga aggaggacgc ccagaaggtg
     1981 ctgaagtgta tgtactgcgg acactccttc gagtccttgc aagacctcag tgtccacatg
     2041 atcaaaacaa agcattacca gaaagtgcct ctgaaggagc ccgtgccagc catcaccaaa
     2101 ctggtccctt ccaccaagaa gcgagcactc caggacctgg catccccttg ttccccagag
     2161 cccacgggcg tggccactga ggttgcactg agtgagtcag ccaaggacca gaaaacggcc
     2221 aacccgtacg tgactccgaa caaccgttac ggctaccaga atggtgctag ttacacgtgg
     2281 cagttcgagg cccgcaaagc ccagatactc aagtgcatgg aatgtggcag ctcccatgat
     2341 accttgcagc agctcacagc ccacatgatg gtcactggcc atttcttaaa ggtgacaacc
     2401 tctgcctcca agaaaggaaa gcagctggtg ttggaccccg tggtggagga gaagatccag
     2461 tccatcccgt tgcccccgac cactcacacc cggctgcctg cctctagcat caagaagcaa
     2521 ccggactctc ctgcgggctc tgtagcctca gaagagaaga aggaacctga gaaggagaag
     2581 gaaaaggaga aagccccacc ggcagctggg gatgcagaga gaaaaatcaa agaggagact
     2641 gaagatgcca ctgagaagtt tgagcccact gccctttatc agtacctgcg tgaggaagac
     2701 ctagatgaca gccccaaggg aggagtagat atcctaaagt cactcgagaa cactgtgtcc
     2761 acggccatca gtaaagccca gaatggggca ccctcatggg gtgggtaccc cagcatccat
     2821 gcagcctacc agctgccagg cacagtgaag ccactgcagt ctgctgtgca gagcgtgcaa
     2881 atacagccgt cttacgccag cagcgtgaag tcactgtcct ccacagagca caatgccctc
     2941 ctacactccc cagggagcct caccccgcca ccccataaga gcaatgtgtc tgccatggag
     3001 gagttagtag agaaggtcac gggcaaggtc agcatcaaga aggaggagag gcctactgag
     3061 aaggagaaga gctcccctgt caaagccatc tctcctgtgg caaaggagaa taaagatctt
     3121 cctaagacag aggagaccgg gagcaagcca cagaagaagg gctcggattc agaaactggg
     3181 aaggccaaaa aggagagtac attggacgct cacaccccaa atggtacaga acctcttaaa
     3241 gccaaggtca ccaatggctg cggccatctg ggtatcatca cggaccactc gccggagcct
     3301 tctttcatca accctctaag cgctctgcag tccatcatga acacccacct aggaaaggtg
     3361 tccaagcccg tgagcccctc tctggatcca ctggcgatgc tctacaagat cagcaacagc
     3421 atgctggaca agcccgtcta ccccacgacc cctgccaagc aggctgatgc aatcgaccgc
     3481 tactactatg agaacagcga ccagcccatt gatctgacca agtctaagaa caagccactg
     3541 gtctcgggtg tggcagatgc tgtgtcctcg cctctgcggg agagcgccct catggatatc
     3601 tcggacatgg tgaaaaatct cacaggtcgt ctgactccca agtcctccac accctccacg
     3661 gtgtcagaga agtcagatgc agatgggagc agctttgagg aggccctgga cgagctgtca
     3721 cctgttcaca agagaaaggg gcgccagtcc aattggaacc cacaacacct gctcatcctg
     3781 caggctcagt ttgcctccag ccttcgagag acagcagaag ggaaatacat catgtcagac
     3841 ctgggccctc aggagcgggt gcacatctcc aagttcacgg gcctatccat gaccaccatc
     3901 agtcactggc tggccaacgt gaagtaccag ctgcggagga cagggggaac caagttcctt
     3961 aagaacctcg acacagggca tcctgttttc ttttgtaatg attgtgcctc tcagttcaga
     4021 actgcctcca cgtacgtcag tcacctggag acgcacctag gcttcagctt gaaggacctc
     4081 tccaagctgc cactcagtca gatacaagag cagcagagtg tcgtctccaa agccctcacc
     4141 aacaagactc tgggcccgct gggctcctcc gaggaagacc tgggctccac attccaatgc
     4201 aagctctgca accggacttt tgcgagcaag cacgcagtaa aactgcacct tagtaagacg
     4261 cacggcaagt cgccagagga ccacctgatc tacgtgacag agctggagaa gcaatagtgt
     4321 gccggtgtgc aggtggctgc agagtactgt actccctctc ttgctgcact aggcctggcc
     4381 tggcctggac ctcggaaatc agtctctcct ttgttgctga cctgcctatc tggacttggt
     4441 ttttctcaca catattttgt agttatattt atatgctctt tgtctgatct gtgcatgtta
     4501 tttttctttt cttttttctt tttctttccg tgagtcaaag tctgaccttt attttcagca
     4561 tccgttcttg ttgttaagct atcttttgta ggaaatagtg ggggcacgct tcggagacat
     4621 tgtttagcag taaagaaaaa gatacaaata gcagcgataa agagacatcc taaaattaca
     4681 aagttgccat gacaataaag gtcacaggac ctggtagtgt caagtttaac cctttgagga
     4741 ctttatctct gtgcctttca ctcaaaaatt aaaaaaaaaa aagaaattaa aaaaaaaaag
     4801 aaagaaaaaa gggggggaaa ggcgcttaaa tgcatttcat tcagatcaaa agctgtgtca
     4861 gacacaaaac ttatttaata attaaaaaac gagctattat atgcaggact ggtttgtgac
     4921 aagacatgca tgcagcggtt ggagacggaa agctgtctag gactcatggg gttaggaagc
     4981 cacaacttta tatgttcaaa acaaaaacaa tgaacacccc agttgccact atgcccaaac
     5041 cctctggatg ctgaaaaatg ccacttttgg caaaaaaaaa agtatgcaag cttattattt
     5101 aaaaaaaagt gtaaaaatgc tatttctttt ttttcctgta aaatactgca gtttatagtt
     5161 atttacaaat gtaagctttg gtatcagctg acctttctat agcgtgatgc attggtaaat
     5221 gaaaaaaaaa aacacagaaa aaaaaaaacc aaaaaaaaaa aagggggcaa atgttggatt
     5281 ctttccttgt aaactgccag catcagctta cacatgcctg tatgttacat atcatatcat
     5341 tttaatcgac ccaactttct ttgtaccttc tggctgtatg ctttctcttt taacttttta
     5401 tattgtcatt ttatattaaa tttctgtgta tataatgtaa aaccacaatt tttggataaa
     5461 atttagttcc tgcagcttga tttaaataga gaaaaattac ctgcccttgc atcttctcag
     5521 atgcatgtac tcagaggaac tatcagacaa aaaaataaat aaatgaaaaa aaaaaaacag
     5581 agcaagcagt gcactattaa ttatacattt tgatgtcctg tcattaatat tgtacagtcc
     5641 gttttggttc acacaattaa atccactgtt ttctcaaatg taaaataaat ccacatgcag
     5701 ttcttgattt acagaga
//
