LOCUS       NM_001164204            1555 bp    mRNA    linear   ROD 21-DEC-2022
DEFINITION  Mus musculus tRNA splicing endonuclease subunit 34 (Tsen34),
            transcript variant 1, mRNA.
ACCESSION   NM_001164204
VERSION     NM_001164204.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1555)
  AUTHORS   Timmermans S and Libert C.
  TITLE     Overview of inactivating mutations in the protein-coding genome of
            the mouse reference strain C57BL/6J
  JOURNAL   JCI Insight 3 (13), 121758 (2018)
   PUBMED   29997285
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1555)
  AUTHORS   Suzuki H, Fukunishi Y, Kagawa I, Saito R, Oda H, Endo T, Kondo S,
            Bono H, Okazaki Y and Hayashizaki Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC171680.5.
            
            [WARNING] On Apr 25, 2023 this sequence was replaced by
            NM_001164204.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (a). Both variants 1 and
            2 encode the same isoform (a).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002684.1, BU514181.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-280               AC171680.5         106943-107222
            281-527             AC171680.5         107931-108177
            528-777             AC171680.5         108311-108560
            778-1047            AC171680.5         108685-108954
            1048-1555           AC171680.5         113861-114368
FEATURES             Location/Qualifiers
     source          1..1555
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7"
     gene            1..1555
                     /gene="Tsen34"
                     /gene_synonym="0610027F08Rik; Leng5"
                     /note="tRNA splicing endonuclease subunit 34"
                     /db_xref="GeneID:66078"
                     /db_xref="MGI:MGI:1913328"
     exon            1..280
                     /gene="Tsen34"
                     /gene_synonym="0610027F08Rik; Leng5"
                     /inference="alignment:Splign:2.1.0"
     exon            281..527
                     /gene="Tsen34"
                     /gene_synonym="0610027F08Rik; Leng5"
                     /inference="alignment:Splign:2.1.0"
     CDS             285..1235
                     /gene="Tsen34"
                     /gene_synonym="0610027F08Rik; Leng5"
                     /EC_number="4.6.1.16"
                     /note="isoform a is encoded by transcript variant 1;
                     leukocyte receptor cluster (LRC) member 5; tRNA-splicing
                     endonuclease subunit Sen34; tRNA-intron endonuclease
                     Sen34; leukocyte receptor cluster member 5 homolog; tRNA
                     splicing endonuclease 34 homolog"
                     /codon_start=1
                     /product="tRNA-splicing endonuclease subunit Sen34 isoform
                     a"
                     /protein_id="NP_001157676.1"
                     /db_xref="CCDS:CCDS20725.1"
                     /db_xref="GeneID:66078"
                     /db_xref="MGI:MGI:1913328"
                     /translation="MLVVEVANGRSLVWGAEAVQALRERLGVGGRTVGALPRGPRQNS
                     RLGLPLLLLPEEARLLAEIGAVTLVSAPRPDPRNHGLALASFKRQQEQSFQDQNTLAA
                     EARETRRQELLEKIVEGQAAKKQKLEQDSGADEGGQEAGGSEATQGSETSDDGQPSAE
                     QEGAAPSLDSSSPQPGPSNGVTPLPRSALLIQLATARPRPVKAKPLDWRVQSKDWPHA
                     GRPAHELRYSIYRDLWERGFFLSAAGKFGGDFLVYPGDPLRFHAHYIAQCWSAEDPIP
                     LQDLVSAGRLGTSVRKTLLLCSPQPDGKVVYTSLQWASLQ"
     exon            528..777
                     /gene="Tsen34"
                     /gene_synonym="0610027F08Rik; Leng5"
                     /inference="alignment:Splign:2.1.0"
     exon            778..1047
                     /gene="Tsen34"
                     /gene_synonym="0610027F08Rik; Leng5"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1555
                     /gene="Tsen34"
                     /gene_synonym="0610027F08Rik; Leng5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttgggggcga ggccagagca atgaccctca aggtcccatt tgtgcagacc ggagtggcag
       61 tgagggcttt cttggctttt ccgctttgct gacctgacgg gatgacggag gacgcgctac
      121 gtagggccag ctccgcctta gccgagagtt ggtgttggct aggggttgac ttattgcctc
      181 tgcctgagga cagtacgaca gattgaaagg gagccacgac gcacactgca cctcgagtgc
      241 gactgtggat tcaatcgtaa ttgtgaactc cttaaattgg gaagatgctg gtggtggagg
      301 tcgcaaatgg ccgctcgctg gtgtggggag ccgaggccgt gcaggcgctg cgggagcgtc
      361 tgggagtcgg gggacgcacg gtgggcgccc tgccccgcgg gccccgccag aactcgcgcc
      421 tgggccttcc gcttctgctg ctgcctgaag aagcccggct cctggccgag ataggcgcgg
      481 tgaccctagt cagcgccccg cgcccggacc cccgcaacca tggcttggcc ctagcatcgt
      541 tcaaacgcca gcaagagcag agtttccagg atcagaacac tttggcagcc gaggcccggg
      601 agacccggcg tcaggagctt ctagagaaga tcgtagaggg ccaggctgcc aagaagcaga
      661 agctggaaca ggattcaggg gcagatgaag gaggccaaga agccggtgga agtgaggcta
      721 cccaagggag tgagaccagt gatgatggcc agccttctgc ggagcaggag ggagcagccc
      781 catccctaga ttcttcatct ccccaaccag gaccttcaaa tggggtgact cccttgccca
      841 gatcagccct gcttatccag ctggccactg ccaggcctcg gcctgtaaaa gctaagcctc
      901 tggactggcg tgtgcagtcc aaagactggc cccatgctgg ccgtcctgcc cacgagctgc
      961 gctacagcat ctaccgagac ctgtgggaga gaggtttctt cctcagcgca gcagggaagt
     1021 ttggtggtga cttcctggtc tatcctggtg atccactgcg tttccatgct cactacattg
     1081 ctcagtgctg gtctgctgag gaccccatcc cacttcagga cctggtctct gcaggccgcc
     1141 tgggaaccag tgtcaggaag accctgctgc tctgctcccc tcagcctgat gggaaggtgg
     1201 tctacacatc cctgcagtgg gccagcctgc agtgagctgg agactgtgtg tggcaagaac
     1261 cctcttcaat ggtcacccca gctcatctct gcacggaggc ttgcgctctc ctgctctgcc
     1321 tggtttgttc cgattccagg gttttgaaca ctacatcctt tctgtttgtt ttttggtttt
     1381 gtttttcctg ttttaaggcg attactacct gtgttgttct ttattttgtt tccaaattgt
     1441 gcttgttgag catggagact gcttttgttt ggcttttgtg tttcttgcgg ggcttaggtt
     1501 cctgcagttc taataaattt gttgaataaa tgtttgtatt ttgagtcctt acaac
//
