LOCUS       NM_001001445            3587 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus transient receptor potential cation channel, subfamily
            V, member 1 (Trpv1), mRNA.
ACCESSION   NM_001001445 XM_006532581 XM_006536294 XM_112546
VERSION     NM_001001445.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3587)
  AUTHORS   Wang,K., Mitoh,Y., Horie,K. and Yoshida,R.
  TITLE     Exploring the Role of Ccn3 in Type III Cell of Mice Taste Buds
  JOURNAL   J Neurochem 169 (1), e16291 (2025)
   PUBMED   39709613
REFERENCE   2  (bases 1 to 3587)
  AUTHORS   Kang,H.J., Krumm,B.E., Tassou,A., Geron,M., DiBerto,J.F.,
            Kapolka,N.J., Gumpper,R.H., Sakamoto,K., Dewran Kocak,D.,
            Olsen,R.H.J., Huang,X.P., Zhang,S., Huang,K.L., Zaidi,S.A.,
            Nguyen,M.T., Jo,M.J., Katritch,V., Fay,J.F., Scherrer,G. and
            Roth,B.L.
  TITLE     Structure-guided design of a peripherally restricted chemogenetic
            system
  JOURNAL   Cell 187 (26), 7433-7449 (2024)
   PUBMED   39631393
REFERENCE   3  (bases 1 to 3587)
  AUTHORS   Fattori,V., Zaninelli,T.H., Rasquel-Oliveira,F.S., Heintz,O.K.,
            Jain,A., Sun,L., Seshan,M.L., Peterse,D., Lindholm,A.E.,
            Anchan,R.M., Verri,W.A. Jr. and Rogers,M.S.
  TITLE     Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling
            drives endometriosis-associated pain and lesion growth in mice
  JOURNAL   Sci Transl Med 16 (772), eadk8230 (2024)
   PUBMED   39504351
REFERENCE   4  (bases 1 to 3587)
  AUTHORS   N'Guetta,P.Y., McLarnon,S.R., Tassou,A., Geron,M., Shirvan,S.,
            Hill,R.Z., Scherrer,G. and O'Brien,L.L.
  TITLE     Comprehensive mapping of sensory and sympathetic innervation of the
            developing kidney
  JOURNAL   Cell Rep 43 (10), 114860 (2024)
   PUBMED   39412983
REFERENCE   5  (bases 1 to 3587)
  AUTHORS   Yang,Y., Gu,X., Weng,W., Cheng,J., Huang,O., Pan,S.J. and Li,Y.
  TITLE     SUMOylation-induced membrane localization of TRPV1 suppresses
            proliferation and migration in gastric cancer cells
  JOURNAL   Cell Commun Signal 22 (1), 465 (2024)
   PUBMED   39350261
  REMARK    Erratum:[Cell Commun Signal. 2024 Oct 7;22(1):479. doi:
            10.1186/s12964-024-01864-8.. PMID: 39375780]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3587)
  AUTHORS   Vlaskovska,M., Kasakov,L., Rong,W., Bodin,P., Bardini,M.,
            Cockayne,D.A., Ford,A.P. and Burnstock,G.
  TITLE     P2X3 knock-out mice reveal a major sensory role for urothelially
            released ATP
  JOURNAL   J Neurosci 21 (15), 5670-5677 (2001)
   PUBMED   11466438
REFERENCE   7  (bases 1 to 3587)
  AUTHORS   Davis,J.B., Gray,J., Gunthorpe,M.J., Hatcher,J.P., Davey,P.T.,
            Overend,P., Harries,M.H., Latcham,J., Clapham,C., Atkinson,K.,
            Hughes,S.A., Rance,K., Grau,E., Harper,A.J., Pugh,P.L.,
            Rogers,D.C., Bingham,S., Randall,A. and Sheardown,S.A.
  TITLE     Vanilloid receptor-1 is essential for inflammatory thermal
            hyperalgesia
  JOURNAL   Nature 405 (6783), 183-187 (2000)
   PUBMED   10821274
REFERENCE   8  (bases 1 to 3587)
  AUTHORS   Caterina,M.J., Leffler,A., Malmberg,A.B., Martin,W.J., Trafton,J.,
            Petersen-Zeitz,K.R., Koltzenburg,M., Basbaum,A.I. and Julius,D.
  TITLE     Impaired nociception and pain sensation in mice lacking the
            capsaicin receptor
  JOURNAL   Science 288 (5464), 306-313 (2000)
   PUBMED   10764638
REFERENCE   9  (bases 1 to 3587)
  AUTHORS   Ma,Q., Fode,C., Guillemot,F. and Anderson,D.J.
  TITLE     Neurogenin1 and neurogenin2 control two distinct waves of
            neurogenesis in developing dorsal root ganglia
  JOURNAL   Genes Dev 13 (13), 1717-1728 (1999)
   PUBMED   10398684
REFERENCE   10 (bases 1 to 3587)
  AUTHORS   Caterina,M.J., Rosen,T.A., Tominaga,M., Brake,A.J. and Julius,D.
  TITLE     A capsaicin-receptor homologue with a high threshold for noxious
            heat
  JOURNAL   Nature 398 (6726), 436-441 (1999)
   PUBMED   10201375
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL663116.7 and AK051315.1.
            
            On or before Sep 4, 2014 this sequence version replaced
            XM_006532581.1, XM_006536294.1, NM_001001445.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK051315.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AL663116.7         35973-36115
            144-1593            AK051315.1         2-1451
            1594-1594           AL663116.7         46144-46144
            1595-3504           AK051315.1         1453-3362
            3505-3587           AL663116.7         63064-63146
FEATURES             Location/Qualifiers
     source          1..3587
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 45.25 cM"
     gene            1..3587
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /note="transient receptor potential cation channel,
                     subfamily V, member 1"
                     /db_xref="GeneID:193034"
                     /db_xref="MGI:MGI:1341787"
     exon            1..219
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            220..536
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            537..703
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            704..856
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            857..997
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1296
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1297..1476
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1635
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1636..1731
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1732..1802
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1803..1968
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1969..2035
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2036..2355
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2356..2483
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2484..2599
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     exon            2600..3587
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3483..3488
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /note="hexamer: AATAAA"
     polyA_site      3507
                     /gene="Trpv1"
                     /gene_synonym="OTRPC1; TRPV1alpha; TRPV1beta; VR-1; Vr1"
                     /note="major polyA site"
ORIGIN      
        1 tgggaatcgg agccgtggca acagcagctg ctgccattgc tgcaaatgtt tccttgagtg
       61 ccagagtatg cccagagccc atccctgccg tacaccaggg gaggggcgag gaccctcaca
      121 gaggcaggga ggccactctt accacacagc agcctggctc tcccacaaag aacagctcca
      181 aggcacttgc tccatttgga gtgtgcctgc acctagctgg ttgcaaattg ggccacagaa
      241 gatctggaaa ggatggagaa atgggctagc ttagactcgg atgaatctga gcccccagcc
      301 caagagaact cctgcccgga ccctccagac agagacccta actccaagcc gcctccagcc
      361 aagccccaca tctttgctac caggagtcgc acccggcttt ttgggaaggg tgactcagaa
      421 gaggcctctc ccatggactg cccttatgag gaaggcgggc tggcctcctg ccctatcatc
      481 accgtcagct ctgttgtcac tctccagagg tctgtggatg gacctacctg tctcaggcag
      541 acatcccagg actctgtctc cactggtgtt gagacgcccc caaggctcta tgatcgcagg
      601 agcatcttcg acgctgtggc tcagagcaac tgccaggagc tggagagcct gctgtccttc
      661 ctgcagaaga gcaagaagcg cctgactgac agcgagttca aagacccaga gacgggaaag
      721 acctgtctgc tcaaagccat gctcaatctg cacaatgggc agaacgacac cattgctctg
      781 ctcctggaca ttgcccggaa gacagatagc ctgaagcagt ttgtcaatgc cagctacaca
      841 gacagctact acaagggcca gacagcatta cacattgcca ttgaaaggcg gaacatggca
      901 ctggtgaccc tcttggtgga gaatggagca gatgtccagg ctgctgctaa cggggacttc
      961 ttcaagaaaa ccaaagggag gcctggcttc tactttggtg agctgcccct gtccctggct
     1021 gcgtgcacca accagctggc cattgtgaag ttcctgctgc agaactcctg gcagcctgca
     1081 gacatcagtg cacgggattc ggtgggcaac acggtgctgc acgcccttgt ggaggtggca
     1141 gataacacag ctgacaacac caagttcgtg acaaacatgt acaacgagat cctgatcctg
     1201 ggggccaaac tccaccccac actgaagcta gaagaactca ccaacaagaa ggggcttaca
     1261 ccgctggctc tggctgccag cagtgggaag attggggtct tggcctacat tctccagagg
     1321 gagatccacg aaccagagtg ccggcacctg tccaggaagt tcactgaatg ggcctatggg
     1381 cccgtgcact cctcccttta tgacctgtcc tgcattgaca cctgtgagaa gaattcagtg
     1441 ctggaggtga tcgcctacag tagcagtgag acccccaacc gccacgacat gcttctcgtg
     1501 gagcccttga accgactcct gcaggacaag tgggacagat ttgtcaagcg catcttctac
     1561 ttcaacttct tcgtctactg cttgtatatg atcatcttca ccacggctgc ttactatcgg
     1621 cctgtggaag gcttgccccc ctataagctg aataacaccg ttggggacta tttccgtgtc
     1681 actggagaga tcctgtctgt gtcaggagga gtctacttct tcttccgagg gatccagtat
     1741 ttcctgcaga ggcgaccatc cctcaagagt ttgtttgtgg acagctacag tgagatactt
     1801 ttctttgtac agtcactgtt catgctggtg tctgtggtac tgtacttcag ccatcgcaag
     1861 gagtatgtgg cttccatggt gttctccctg gccatgggct ggaccaacat gctctactac
     1921 acccgaggat tccagcagat gggcatctat gctgtcatga ttgagaagat gatcctcaga
     1981 gacctgtgtc ggtttatgtt cgtctacctc gtgttcttgt ttggattttc cacagccgta
     2041 gtgacactga tcgaggatgg gaagaataac tcactgcctg tggagtcccc accacacaag
     2101 tgtcggggat ctgcctgcag gccaggtaac tcttacaaca gcctgtattc cacatgtctg
     2161 gagctgttca agttcaccat cggcatgggt gacctggagt tcaccgagaa ctatgacttc
     2221 aaggctgtct tcatcatcct gttactggcc tatgtgattc tcacctacat cctcctgctc
     2281 aacatgctca ttgctctcat gggcgagact gtcaacaaga ttgcacaaga gagcaagaac
     2341 atctggaagc tgcagcgagc catcaccatc ctggatacag agaagagttt cctgaagtgc
     2401 atgaggaagg ccttccgctc cggcaagctg ctgcaggtgg ggttcacgcc ggacggcaag
     2461 gatgacttcc ggtggtgctt cagggtggat gaggtgaact ggactacctg gaacaccaac
     2521 gtgggcatca tcaacgagga cccaggcaac tgtgagggcg tcaagcgcac cctgagcttc
     2581 tccctgcggt caggccgagt ttcagggaga aactggaaga actttgccct ggttcccctt
     2641 ctgagggacg caagcactcg agataggcat agcacccagc cggaagaagt tcagctgaag
     2701 cactatacgg gatcccttaa gccagaggat gctgaggtct tcaaggattc catggcccca
     2761 ggggagaaat gagggacacc atgaagcagc tgatgctggg tctttgggtg gcccattgct
     2821 cccgtgggga aggatctact cagggagcaa tagagccggg ttgatgttgg ctggctgtac
     2881 tctgcctgcc taggcatgtc cctaggactt cactgggcct gctgtgggaa ggtgggaggt
     2941 gtgtgggaag cgagctgtga atctaaccat gatcttcaaa catttggctt tcaactcttt
     3001 actggcttta ttaaacagaa tggatggcag agctctactt ggacacaggt cagatcctgg
     3061 ttttatttga cttttggatg gctgggacta tgaacaaatg gagtccaagc agacaacctt
     3121 taactacttg ctttgatatg aaatgctggg tcatttctcc cctacgctct gctgactatc
     3181 ttacctggga ggttttggag ggttttgcca tttggtgaac gcagagaaag tgggggtacg
     3241 ctggggttca ccagtctcac tatcaattcc atcagaatca ggttgtgact ttccccttca
     3301 atgtaaaata tctgtcctcc ccccaaaaca gtagcttcat tgctgtttaa ataaaaatat
     3361 agaggcacac tcaaaggaca tgcagaaaaa tctcaatgat ctttcatttg ttgtaatcat
     3421 aattttgccc cactctgtgc agtgctaaat gtacctaccg ctgttagtct tgtaattaat
     3481 aaaataaact atgtgtgtgt ctgcaaatac gctttgtaac aagtgtggac ttggccatag
     3541 taattgggct ggtgttgcta cgtgtttctc tgttcagtct gtttgtg
//
