LOCUS       NM_176952               3841 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus tRNA methyltransferase 9B (Trmt9b), transcript variant
            3, mRNA.
ACCESSION   NM_176952 XM_030243608
VERSION     NM_176952.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3841)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3841)
  AUTHORS   Codner,G.F., Mianne,J., Caulder,A., Loeffler,J., Fell,R., King,R.,
            Allan,A.J., Mackenzie,M., Pike,F.J., McCabe,C.V., Christou,S.,
            Joynson,S., Hutchison,M., Stewart,M.E., Kumar,S., Simon,M.M.,
            Agius,L., Anstee,Q.M., Volynski,K.E., Kullmann,D.M., Wells,S. and
            Teboul,L.
  TITLE     Application of long single-stranded DNA donors in genome editing:
            generation and validation of mouse mutants
  JOURNAL   BMC Biol 16 (1), 70 (2018)
   PUBMED   29925374
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3841)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC168051.3.
            
            On or before May 28, 2020 this sequence version replaced
            XM_030243608.1, NM_176952.4.
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK141601.1, SRR7345562.3105364.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849386, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-298               AC168051.3         109038-109335
            299-500             AC168051.3         139996-140197
            501-655             AC168051.3         149279-149433
            656-829             AC168051.3         156504-156677
            830-3841            AC168051.3         162525-165536
FEATURES             Location/Qualifiers
     source          1..3841
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 23.05 cM"
     gene            1..3841
                     /gene="Trmt9b"
                     /gene_synonym="6430573F11Rik; Kiaa1456; TRM9L"
                     /note="tRNA methyltransferase 9B"
                     /db_xref="GeneID:319582"
                     /db_xref="MGI:MGI:2442328"
     exon            1..298
                     /gene="Trmt9b"
                     /gene_synonym="6430573F11Rik; Kiaa1456; TRM9L"
                     /inference="alignment:Splign:2.1.0"
     exon            299..500
                     /gene="Trmt9b"
                     /gene_synonym="6430573F11Rik; Kiaa1456; TRM9L"
                     /inference="alignment:Splign:2.1.0"
     exon            501..655
                     /gene="Trmt9b"
                     /gene_synonym="6430573F11Rik; Kiaa1456; TRM9L"
                     /inference="alignment:Splign:2.1.0"
     exon            656..829
                     /gene="Trmt9b"
                     /gene_synonym="6430573F11Rik; Kiaa1456; TRM9L"
                     /inference="alignment:Splign:2.1.0"
     exon            830..3841
                     /gene="Trmt9b"
                     /gene_synonym="6430573F11Rik; Kiaa1456; TRM9L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2245..2250
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trmt9b"
                     /gene_synonym="6430573F11Rik; Kiaa1456; TRM9L"
                     /note="hexamer: AATAAA"
     polyA_site      2270
                     /gene="Trmt9b"
                     /gene_synonym="6430573F11Rik; Kiaa1456; TRM9L"
                     /note="major polyA site"
ORIGIN      
        1 gtactcccaa aaacccttcc ccgccccctg tccctctctc tagtcctctc cctttcattc
       61 tcacgctcct aggccgaccc gtggaagttg catcctggat agcccgggct gcgctactga
      121 agagctccga gctagagctc ggccgagcct cccgcccgga tcccgggcaa agaccgccca
      181 aaacctggtg ctgaccttcg tctgcaccgc tctatggtga cccgaatctc cgctgcccga
      241 gttgcagcgg ctgtgcaccc caaggactgc cagagcgccc gggaatctgc aagcctgggg
      301 cctggattct cttcagagac tcatactgag cggtagaacc tgtgaagggt aaaggattgg
      361 actcattgac ttgattcgct cttcgtccac ttgtgttata tactgagaga gtcccaagaa
      421 gcaactgttc actctgagaa aagaagccac catgattgac caaaacaaga agtaatccac
      481 gtgatcacaa gatgagtcag gatggatcct gaagctgtgg aactggagaa gcgacatgtg
      541 cacagtgtgt acgagaacac tgccccctac ttcactgacc tgcagagcaa agcctggccg
      601 cgtgtccgcc agttcctgca ggaccagaag ccaggcagcc tcgtcgctga cattggttgt
      661 ggaactggaa agtatcttaa agtgaatagc caagtccata ctctgggctg tgactactgt
      721 gggcctctgg tagagattgc ccggaataga gggtgtgaag tcatggtatg tgacaacctt
      781 aatcttccct ttagggacca gggcttcgat gctatcatct ccataggagt catacatcat
      841 ttttctacaa aagaaagaag aattagagca ataaaggaaa tggccagggt tttagctccc
      901 ggaggccagt tgatgattta tgtctgggca atggaacaga agaaccgacg ctttgagaaa
      961 caggatgtac ttgtgccgtg gaacagggca ctctgttccc ggctgctgtc agaatcccac
     1021 cagtcatggg gtcatcactg tgagcatccc aggagccgag gcttccaggg ccccggttcc
     1081 gtgtgcggct gcgcagtgtg ttttaagggc agatgtgatt ccaaacggtc ccacagcatg
     1141 gactatgggt ctgcggtggc cagaacctgc tgcgaagcta tttcaaagga aggcgagcga
     1201 gagaacggat tgtatagcaa ttttgggaaa tcctttcgtt cctggttttt ctccaggtct
     1261 ttggatgaat caaccctgag gaagcaaatt gaaagagtca ggcccatgaa aatcccagag
     1321 gcttgggcca atagcaccgt gtcccaacag ccttccagac accccagctt agacttgcac
     1381 gctccggagc cattttcaac aaaaggacca aacttagatg aggtgttcgt agacacatct
     1441 tctcaaagac acttgggctg gctgagaaca cctggcacat cagacaactt cagtggacac
     1501 aagggaggag ggagcaggag gaaggagggg ggcaattttc tggacatcac tgataccggg
     1561 gacagtgtgg ctgctagtaa cagcagtgat ccttctgcca gaaaaatatt aaggagggtt
     1621 tctgcattcg actccaacga ctccaactca gaagactcaa gctttttgga agcacaacgg
     1681 gatgccaccg attccaaagc cttcatgcgt tactaccatg tatttcggga aggtgagctc
     1741 tccagcctgc tgcaggagag tgtgtctgag ctacaggttc tgagctccgg caatgaccat
     1801 ggtaactggt gcatcattgc agagaaaaag aggagctggg attaaacgac acggctcaag
     1861 gcagaggcta cggtggtggc ctatcatctg ttcaacgggg ctggtgtggg taccagaagc
     1921 agcatcctgt ttcattgttt tcaaatccag gtacgagttg gtacttaagc actttgaccg
     1981 catcttccta attgttgagt aagcacgaag tctgacacgt actgcatctg ctacaggatc
     2041 tgcctgctga agtttcaata agagaatctg aggaagcaat aggaactgaa ctttaagtat
     2101 aggcttgatc ttcttcctcc cagtgatgaa attattataa tatgtgtatg tcaagcgtca
     2161 gtattatctt ttggttttta aatattctgc tgttaagtat accctttaaa agcagtttgt
     2221 ttgtttgttt gtttgtttgt tttaaataaa ttgcattggt tctcaggtaa ttacttagac
     2281 ctctgtggaa ggaacaagga cacctgttct gtggctgggt gtgtttgaga cttgctgtgg
     2341 gggtgtcttg tttcctgact ttgttgctaa ctacgtcaag ccttctaata ttgcccagat
     2401 gttctaaatt acatgcaaac atcgtttggg atgagcagtg ttaataatac tgtcttcagt
     2461 gttgctctga agcttcttaa aggcgctgtt agcagagggt tagtgttaga gcagccagct
     2521 cgaatgccgc agaatcagca tatatccaca gtaccacaga tagaatttaa aaaaaataat
     2581 aataaacaca ctgttagcat gtagagagtg ttacatgggt aggagatgtt ctgtcctctg
     2641 gtgacatttt ctccaaaggt attaggagca taaatagcca agtgaggttg tgccaaaatt
     2701 acccaaagag ttttcaacta ggaaatgctc atcagttatc ggagtctaat tggagctgtt
     2761 ttactttgcc tgtggggaca gatctggaaa gtgtcatgta tttagcctta gtggacacat
     2821 aattgggact tgcagttgca tgccatggca tttattccct tgaaggtaac tgcattagat
     2881 cgttatatca acaatctgga cagaatcgaa gcttagtcac aggttgaatt tctgctagtc
     2941 tatagtgcaa tgattcatct gggcattgta acaaaatcca tgcctttttt ttttttaaga
     3001 ctaaaccacg actgtgatta attctatgtt gtggatccca aggaacaatt atgaaggaac
     3061 aagagactag gcccgggaga aacaaaaata agttggccac ggaatatggt tccagataat
     3121 tcgttaacaa gcagaaaatc aaatagtcat tgtgctttct ggaccaatat aatgatggag
     3181 attagattaa aatccaatct tcattttatt ttttctccca ctacaaaatt aacaaaaatt
     3241 gtaatggatc atatatttat ttggttgttt atcctcttca gagattttgt gggagcgtaa
     3301 caaaaaggaa gctacttttg aagacaaatt caaaggtgat ttgaaaaatg caacaatgtg
     3361 tcttttaaac tttaaaagtg tatagctcct gaagttcttc aagtcaaatt tccatctcct
     3421 cacccctgtg gtgggagtgg taggcatgtc ttataatttt ttgtgtacat tttgtacagg
     3481 gagacatgaa aatagacaca ggggtgaagt ataagttaaa atctactgta ccttttactt
     3541 ttccaagtga aaatattaaa ctgtatgtgc agtggcttcc tgggagaaat ggtgactctg
     3601 aattagttag cagtgatgac ctctttatta tggtttcccc cttctctgag atctatgcca
     3661 ctttcacgtg gctttgctgc cagacgtctg agcctgacat caccctgatt gaaatgtgct
     3721 acttaaagct tgttatatgg aacccagttc attaggctgt gccaggatgc tgtaccagct
     3781 aagaacaagc tcaaaaaata aacacacacc tcattttgta tttaaagccc tttggaatgc
     3841 t
//
