LOCUS       NP_082880                460 aa            linear   ROD 05-MAY-2025
DEFINITION  tRNA (guanine(10)-N(2))-methyltransferase TRMT11 isoform 1 [Mus
            musculus].
ACCESSION   NP_082880
VERSION     NP_082880.2
DBSOURCE    REFSEQ: accession NM_028604.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 460)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (residues 1 to 460)
  AUTHORS   Diez-Roux,G., Banfi,S., Sultan,M., Geffers,L., Anand,S., Rozado,D.,
            Magen,A., Canidio,E., Pagani,M., Peluso,I., Lin-Marq,N., Koch,M.,
            Bilio,M., Cantiello,I., Verde,R., De Masi,C., Bianchi,S.A.,
            Cicchini,J., Perroud,E., Mehmeti,S., Dagand,E., Schrinner,S.,
            Nurnberger,A., Schmidt,K., Metz,K., Zwingmann,C., Brieske,N.,
            Springer,C., Hernandez,A.M., Herzog,S., Grabbe,F., Sieverding,C.,
            Fischer,B., Schrader,K., Brockmeyer,M., Dettmer,S., Helbig,C.,
            Alunni,V., Battaini,M.A., Mura,C., Henrichsen,C.N.,
            Garcia-Lopez,R., Echevarria,D., Puelles,E., Garcia-Calero,E.,
            Kruse,S., Uhr,M., Kauck,C., Feng,G., Milyaev,N., Ong,C.K.,
            Kumar,L., Lam,M., Semple,C.A., Gyenesei,A., Mundlos,S., Radelof,U.,
            Lehrach,H., Sarmientos,P., Reymond,A., Davidson,D.R., Dolle,P.,
            Antonarakis,S.E., Yaspo,M.L., Martinez,S., Baldock,R.A., Eichele,G.
            and Ballabio,A.
  TITLE     A high-resolution anatomical atlas of the transcriptome in the
            mouse embryo
  JOURNAL   PLoS Biol 9 (1), e1000582 (2011)
   PUBMED   21267068
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC153899.3, AK032943.1, BY259542.1, AK010722.1 and BG083636.1.
            
            On Sep 6, 2006 this sequence version replaced NP_082880.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK010722.1, AF532979.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 17.07 cM"
     Protein         1..460
                     /product="tRNA (guanine(10)-N(2))-methyltransferase TRMT11
                     isoform 1"
                     /EC_number="2.1.1.214"
                     /note="tRNA guanosine-2'-O-methyltransferase TRM11
                     homolog; tRNA (guanine(10)-N2)-methyltransferase homolog;
                     tRNA methyltransferase 11 homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase homolog; tRNA
                     (guanine(10)-N(2))-methyltransferase TRMT11"
                     /calculated_mol_wt=52808
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:Q7Z4G4; propagated from
                     UniProtKB/Swiss-Prot (Q9CWH5.1)"
     Region          10..335
                     /region_name="TIGR01177"
                     /note="putative methyltransferase, TIGR01177 family"
                     /db_xref="CDD:273486"
     Region          197..383
                     /region_name="Trm11"
                     /note="tRNA G10 N-methylase Trm11 [Translation, ribosomal
                     structure and biogenesis]; COG1041"
                     /db_xref="CDD:440663"
     CDS             1..460
                     /gene="Trmt11"
                     /gene_synonym="2410075D05Rik; 3110045I18Rik"
                     /coded_by="NM_028604.3:40..1422"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /db_xref="CCDS:CCDS23763.1"
                     /db_xref="GeneID:73681"
                     /db_xref="MGI:MGI:1920931"
ORIGIN      
        1 malpgslnry lllmaqehle frlpeiksll svfggqftns qetygkspfw ilnipsedia
       61 rnlmkrtvca ksifelwghg kspeelytsl ksypvekmvp ylhsdstyki kihtfnktlt
      121 qeekvkrida leflpfqgkv nlkkpqhvfs iledygldpn sipkdphniy fgrwiadgqr
      181 eliesysvkk rhfigntsmd aglsfimtnh akvkendlvf dpfvgtggll iasahfgayv
      241 cgtdidyntv hglgkasrkn qkwrgpdeni ranlrqygle kfyldvlvsd askpswrkgt
      301 yfdaiitdpp ygirestrrs gsqkdipkgi ekcpeshvpv slsyhlsdmf fdllnfaaet
      361 lvlggrlvyw lpvytpeyte emvpwhpclr lisnceqkls shtarrlitm ekvkefenrd
      421 kyshllsdhf lpyqghnsfr ekyfsgvtkr iakeekcshe
//
