LOCUS       NM_001357872            6701 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus thyroid hormone receptor interactor 4 (Trip4),
            transcript variant 3, mRNA.
ACCESSION   NM_001357872 XM_006511299
VERSION     NM_001357872.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6701)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6701)
  AUTHORS   Davignon,L., Chauveau,C., Julien,C., Dill,C., Duband-Goulet,I.,
            Cabet,E., Buendia,B., Lilienbaum,A., Rendu,J., Minot,M.C.,
            Guichet,A., Allamand,V., Vadrot,N., Faure,J., Odent,S., Lazaro,L.,
            Leroy,J.P., Marcorelles,P., Dubourg,O. and Ferreiro,A.
  TITLE     The transcription coactivator ASC-1 is a regulator of skeletal
            myogenesis, and its deficiency causes a novel form of congenital
            muscle disease
  JOURNAL   Hum Mol Genet 25 (8), 1559-1573 (2016)
   PUBMED   27008887
REFERENCE   3  (bases 1 to 6701)
  AUTHORS   Knierim,E., Hirata,H., Wolf,N.I., Morales-Gonzalez,S.,
            Schottmann,G., Tanaka,Y., Rudnik-Schoneborn,S., Orgeur,M.,
            Zerres,K., Vogt,S., van Riesen,A., Gill,E., Seifert,F., Zwirner,A.,
            Kirschner,J., Goebel,H.H., Hubner,C., Stricker,S., Meierhofer,D.,
            Stenzel,W. and Schuelke,M.
  TITLE     Mutations in Subunits of the Activating Signal Cointegrator 1
            Complex Are Associated with Prenatal Spinal Muscular Atrophy and
            Congenital Bone Fractures
  JOURNAL   Am J Hum Genet 98 (3), 473-489 (2016)
   PUBMED   26924529
  REMARK    GeneRIF: homozygous and compound-heterozygous nonsense and
            frameshift TRIP4 and ASCC1 mutations that cosegregated with the
            Prenatal Spinal Muscular Atrophy and Congenital Bone Fracture
            phenotype
REFERENCE   4  (bases 1 to 6701)
  AUTHORS   Slater,L.H., Hett,E.C., Clatworthy,A.E., Mark,K.G. and Hung,D.T.
  TITLE     CCT chaperonin complex is required for efficient delivery of
            anthrax toxin into the cytosol of host cells
  JOURNAL   Proc Natl Acad Sci U S A 110 (24), 9932-9937 (2013)
   PUBMED   23716698
REFERENCE   5  (bases 1 to 6701)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   6  (bases 1 to 6701)
  AUTHORS   Lee,Y.S., Kim,H.J., Lee,H.J., Lee,J.W., Chun,S.Y., Ko,S.K. and
            Lee,K.
  TITLE     Activating signal cointegrator 1 is highly expressed in murine
            testicular Leydig cells and enhances the ligand-dependent
            transactivation of androgen receptor
  JOURNAL   Biol Reprod 67 (5), 1580-1587 (2002)
   PUBMED   12390891
REFERENCE   7  (bases 1 to 6701)
  AUTHORS   Jung,D.J., Sung,H.S., Goo,Y.W., Lee,H.M., Park,O.K., Jung,S.Y.,
            Lim,J., Kim,H.J., Lee,S.K., Kim,T.S., Lee,J.W. and Lee,Y.C.
  TITLE     Novel transcription coactivator complex containing activating
            signal cointegrator 1
  JOURNAL   Mol Cell Biol 22 (14), 5203-5211 (2002)
   PUBMED   12077347
  REMARK    GeneRIF: ASC-1 exists as a steady-state complex associated with
            three polypeptides, P200, P100, and P50, in HeLa nuclei.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC151906.3.
            
            [WARNING] On Oct 7, 2024 this sequence was replaced by
            NM_001357872.2.
            
            On Nov 10, 2017 this sequence version replaced XM_006511299.3.
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. Variants 1 and 3 both encode the same isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.41438.1,
                                           SRR9219383.26004.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-356               AC151906.3         34152-34507
            357-602             AC151906.3         57773-58018
            603-772             AC151906.3         61886-62055
            773-906             AC151906.3         63738-63871
            907-1119            AC151906.3         67903-68115
            1120-1198           AC151906.3         69769-69847
            1199-1328           AC151906.3         76345-76474
            1329-1544           AC151906.3         78527-78742
            1545-1671           AC151906.3         84574-84700
            1672-1859           AC151906.3         85435-85622
            1860-1984           AC151906.3         89996-90120
            1985-2076           AC151906.3         91488-91579
            2077-2179           AC151906.3         103909-104011
            2180-6701           AC151906.3         109498-114019
FEATURES             Location/Qualifiers
     source          1..6701
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 35.55 cM"
     gene            1..6701
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /note="thyroid hormone receptor interactor 4"
                     /db_xref="GeneID:56404"
                     /db_xref="MGI:MGI:1928469"
     exon            1..356
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            357..602
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             502..2247
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /note="isoform 1 is encoded by transcript variant 3;
                     transcription coactivator Asc1; activating signal
                     cointegrator 1; thyroid receptor-interacting protein 4;
                     TRIP-4; TR-interacting protein 4"
                     /codon_start=1
                     /product="activating signal cointegrator 1 isoform 1"
                     /protein_id="NP_001344801.1"
                     /db_xref="CCDS:CCDS23298.1"
                     /db_xref="GeneID:56404"
                     /db_xref="MGI:MGI:1928469"
                     /translation="MAVAGAAYREPLVHWCTQQLQKTFALDVSEEIIQYVLSIENAEE
                     IREYVTDLLQGNEGKKGQFIEDLITKWQKNDQEFISDSFQQCLRKDEILDGQRSVDQL
                     KRSRRKGRNKQEVPAFPEPDVAVEVKTPLDLAKAQESNNSVKKKTRFVNLYTREGQDK
                     LAVLLPGRHPCDCLGQKHKLINNCLVCGRIVCEQEGSGPCLFCGSLVCTNEEQDILQR
                     DSNKSQKLLKKLMSGAETSGKVDVSTKDLLPHQESRMKSGLEKAIKHKEKLLEFDRTS
                     IRRTQVIDDESDYFASDSNQWLSKVEREMLQKREEELRELRHASRLSKKVTIDFAGRK
                     ILEDENPLAEYHSRLDETIQAIASGTLNQSLVTLDRSCEEPLGVLVNPNMYQASPQWV
                     DNTGSTPQKKTSLSAGPRLEPSLHQHQLRIQDQEFQEGFDGGWCLSMHQPWASLLVRG
                     IKRVEGRSWYTPHRGRLWIAATGKRPSPQEVSELQATYRLLRGKDVEFPNDYPSGCLL
                     GCVDLIDCLSQKQFQEQFPDISQESDSSFVFICKNPQEMVVKFPIKGNPKIWKLDSKI
                     HQGAKKGLMKQNKAV"
     exon            603..772
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            773..906
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            907..1119
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1198
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..1328
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1544
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1671
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1859
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..1984
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2076
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2077..2179
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2180..6701
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3837..3842
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /note="hexamer: AATAAA"
     polyA_site      3869
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /note="major polyA site"
     regulatory      6548..6553
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /note="hexamer: ATTAAA"
     polyA_site      6576
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
     regulatory      6679..6684
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
                     /note="hexamer: AATAAA"
     polyA_site      6700
                     /gene="Trip4"
                     /gene_synonym="4930558E03Rik; ASC-1; Asc1"
ORIGIN      
        1 atttcttcgg ggactgttgg taagtgggtt gggagcttcg ttttctcatt tggaaatgtt
       61 tttaggcctt tagtttacaa tgttaggcca ggtaaaccct tcgctgcagc aggtagtagg
      121 cccaacgtag ctgcttccat cagttggtct ctgacaccag ctccaaacta cacacacctc
      181 ctggaatcct gggccatctc ggcagctcct cccaaagctc ctctccaggc cccttgcggg
      241 agcttctttc tcactgtcta gcaagcatct ccctctggtg gatttcctgt cgtttcaacc
      301 agacttttgc atgcatttcg ttctgaaccg gctccagaag tcgaacagtg aagtggatcc
      361 ggaagctgag cgaagcctgc gcgaccgagc ggggcggtgc aagcttgcgg aaccttcatc
      421 gacgaggtcg gcgctgcgaa gggaaccagt ccagggcggg acgagaggct tttgcagccc
      481 agctggttcc ggctggggaa gatggcggtg gctggggcgg cgtaccggga gccgctagta
      541 cactggtgca cacagcagtt gcaaaaaact ttcgccctgg atgtcagcga ggaaatcata
      601 caatatgttt tgtcaattga gaatgctgaa gaaatacgag aatatgtgac agaccttctc
      661 cagggaaatg agggcaaaaa gggtcaattc atagaagatc ttataaccaa atggcaaaag
      721 aatgatcaag agttcatctc tgattccttt caacagtgct tgagaaaaga tgaaatttta
      781 gatggacaga gatcagtgga ccagctaaag cggagtagga ggaaaggacg aaacaaacag
      841 gaagttcctg catttcctga acctgacgta gctgtggagg tcaaaacacc tttagatttg
      901 gctaaggcac aagaaagcaa caactccgta aagaagaaga caagatttgt caatttatat
      961 acaagagagg gacaggacaa acttgcagtc ctgcttcctg gtcgtcaccc gtgtgattgc
     1021 ctgggccaga agcacaaact catcaataac tgtctggtct gtgggcggat cgtttgtgag
     1081 caggagggtt caggcccctg cttgttctgt ggctctttgg tgtgtactaa tgaagaacag
     1141 gatattttac agcgggactc aaacaaaagt cagaaactgc tgaagaagct catgtcaggg
     1201 gcagagactt ctggaaaggt ggacgtctct accaaggacc tacttcctca tcaagaatcc
     1261 cgaatgaagt ctggtttgga gaaggctatc aagcataagg aaaaactgtt agagttcgac
     1321 agaacgagta tccgaaggac ccaagttatt gacgatgaat cagattactt tgccagtgat
     1381 tctaaccagt ggctgtccaa agttgagcga gaaatgctgc agaaacgaga ggaggagctg
     1441 agagaactcc gacatgcctc cagactttct aagaaagtga ccattgactt cgcggggcgg
     1501 aagatcctag aagatgaaaa tccactagca gagtatcaca gcagactaga tgagacaata
     1561 caagccattg ccagtgggac tttgaaccag tcactggtca cgttggatag atcttgtgaa
     1621 gagcctttgg gagttctggt aaaccctaac atgtaccagg cctctcctca gtgggttgac
     1681 aacactggct caaccccaca gaagaagact tcactctcgg caggaccaag actagagccc
     1741 agtttacatc agcaccagct gcgaatccag gaccaagaat tccaggaagg ctttgatggc
     1801 ggctggtgcc tgtctatgca tcagccctgg gcttctctgc ttgtcagggg gattaaaagg
     1861 gtggagggca gatcctggta tactcctcac agaggaagac tttggatagc agccacgggc
     1921 aaaagacctt cccctcagga agtctcagaa ctccaggcta cctatcgtct tcttcgtggg
     1981 aaagatgtgg agtttccaaa tgactatccg tcgggttgtc ttctgggctg tgtggacctt
     2041 attgattgct tgtcccagaa acaatttcag gagcagttcc cagacatcag tcaagagtct
     2101 gactcttcat ttgttttcat ctgcaaaaat ccccaggaaa tggttgtgaa gttccctatt
     2161 aaaggaaatc ctaaaatctg gaaactggat tccaagatcc atcaaggagc aaagaagggg
     2221 ttaatgaagc agaataaagc tgtctgaccc aggaaaaaag gaactataca acatagtgga
     2281 gtcttgtgta ctaaagtgct atccgctggg cctttgggat tgaagcagta gaaagcgaaa
     2341 aggctgggca ccaggcttca atctctgaga atctaaactc ttaccaaatc tgtgtatttt
     2401 tcttaaagga tggaattctt tatgaagtgg gttacagatc tttgaatatg ttatttataa
     2461 aaaaatcatt ttaaaaattc taggtcattt ttctcagaac taaattcaaa acaggaagga
     2521 acaaattgga aattattttc ctcagtgaga tttgtatttt gaattaggaa aatctcaaca
     2581 tagattaaca tttttacaag agactctgaa tttaattttt tttctcaaaa taatagaatg
     2641 gagactacta ggatgtctga ggaatctttg tttaacataa gcctatggtg aaatgagaat
     2701 gttcttacca agtgttctgc ttttgacatc ttgagaccag gccacattct gtgacccagg
     2761 cttgcctgga actcacaaca atcctcctgc cgaagcctct caagtgctgt gtttacaggc
     2821 cagtagcccc atgctcagct tctaacccaa atctctcaga gtggaaagct agaattccca
     2881 gtatcagcag attttttttt ctttcttttt ggaaaaggta acatgaagac atacttcctt
     2941 ttgttcttta gtttgagaac atgggttagt ctgggaagtg agggagctac ctgctaatgc
     3001 agcctgaagc tgccctgttt attttgttag tgttgcaaaa gcatcatgta gatgggacaa
     3061 ttagagaaaa acttgaaaat acgatccttt ggtaaataca tcagaaagcc ctctaatgct
     3121 gaaaacaagc ccctttaaac ctataaatat cctaaaaaag ccattactgg aaaaataagg
     3181 ttggtttgaa gtgagatttt tcactggtcc ctttagccct tctcaggaag cacttgtttc
     3241 tgaggctctt ctaaagtgct attggaatct cagttgctgg agcctaggaa attcatggtc
     3301 tcaaatgtgt gtgctctgct ttttataaaa caccactacc acactaggga tgttggactc
     3361 cctccaacag tttgtgtgct tgacttaaaa aagaaagagc aagtgagaaa gaaaaaaaag
     3421 taccttgtgt tatgaaaaag attaatttcc ctttctttaa tccttcatat tcagcattta
     3481 tttgcattga aatgcctcca ctcattccac attgatgttc actcgactgt gaactgcctg
     3541 ttgcatagca ttggttcttc ggaggctgat cactctggat tcccagggaa acccgaacag
     3601 attcttgttc cagtgatgta cacatgcagt attctctctc gtgttctgtt ggacctctgt
     3661 gtataaagtg gaagaggaca gttagtggca tttattattg tgagagatgt ctttttgacc
     3721 tcttggaaac cttaccattg ttgaaagcaa aactgtgttt actatgtagt taatagttta
     3781 ccaagtagta gcaccttgaa ttccatgctg aaattgtctg gctttcttaa tatcacaata
     3841 aaattgaaag gtaggatggg aagagaaaag aaggggttgg aagttctctg ttcttttatt
     3901 tgaagacagc ctttacacag aagagtatgg attgtttttt ctatgtgggt aatttgaatg
     3961 cacaccttaa aagaaaaaag tcaggaatgt caacagatga gctcatctgc ccgagctttg
     4021 caagtttcta agaacccacc tcagcttctc aaacacacag ccagaaccac ataaataaat
     4081 ggcagagcta ctcggaaact tctccttttc atggttaggc tgggaaagtc tgtctttggt
     4141 ttacatggca gtggtagtat aaggtctctc ttctgtttgc tgagacacaa gggaggaagt
     4201 gtgggagaag tttgcgggta gatggccctc agttgctcac tgatgaatag tatactttaa
     4261 agtcagatgg aaattcttag tagcctgagt tcaagcttgt ccaagaatag cttgttagtg
     4321 tattatgaca cttcactctg accctgttac tctggggcag tttcgcctaa gaaagttctg
     4381 aatttccgag atgccttttt gttgtagctt ctgtgttccc ttttgaatga ctgaattaag
     4441 atgccattaa ttcatacagt aaaggaattg gctttttctt tttgtttttc ccagacaaga
     4501 ctcagtttcc tttgtatgag ctcacagtag ggaatgatgg aaactatggg ctttgtcagc
     4561 gttgatgaga ccttatcttt agtgaagtgt ttagaataga ttaagaattt ggccagatgt
     4621 gatagtatac accttaatcc cagcactggg gaggctgatc tcttactatc tcttatatag
     4681 taagtcccta tcacaaagga gaacataaaa agaatttggg tttttgttgc ttctttagct
     4741 aatacagaac taagataata aagaactaag tgtcctatct tttcttttta aactgaaatt
     4801 ttagtgtaaa cctattttcc ccctagcatg taaatgtgag acactacaga gattagtttt
     4861 acaaataagt atagctatgg acttatatga ttatgacatt taattttttt ccattttaat
     4921 tactgtctct cctataaccc attcatgtgg tggccattta atttagaaga tttgtttaat
     4981 gttgtgtggg gcctagccaa gattagatgg catggggctg ttcacttgac cagctcagct
     5041 actaaactag agaaatcagc taacttcagt ttgttaggct gggaggaggg aaggcaatcc
     5101 agagagaaag gatattttct tccttgcgat tcaaatagca agcacacatc tgctattctc
     5161 agtgtctgtg aatgtgtttg ggaggaggtg atccacatgg aaggctccaa cagcaacaag
     5221 ggatccatgc agcctgcaga gagcttttct acttttcgcc tgtagaggaa aaagaacagt
     5281 accatcctac gtcacaatga acttggataa acgtccattt gcatgtgtga atacaatgtg
     5341 gcttcattca ggagatgaaa tgtaaattga tcagatgttg aatttcagtt gtgaaaatgg
     5401 gaaaacccag aaagaaatcc cagtaaaaaa ataccagaga ttggagtcag ggaaaaagga
     5461 gggtgcaggg gtggggtggg gtggtggggg aggtgcctaa atccacagat gtgtcagaaa
     5521 agaagacctg ggcatgaaga gaaaagcaca tcactgcgta agacttcaga agagtctagt
     5581 caggcatggt ggttgtatgc ctttagtcct agcatttggg aggcagaagc aggtggatct
     5641 ctagggtagt gctgcctaat atggtaacca ctggccacat gctgtttaaa tatgaattaa
     5701 tatttaaaaa gccgggcgtg gtggcgcacg cctttaatcc cagcactcga gaggcagagg
     5761 caggcggatt tctgagttca aggccagcct ggtctacaaa gtgagttcca ggacagccag
     5821 ggctatacag aaaaaccctg tctcgaaaaa ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     5881 aaaaagaatt aaaatttaag taaagactca gttcttcagt catcctacct tgagtgccct
     5941 agtagctcat atgtggctag agacttctga acagcagggg gcaggggtta gcaaagtcat
     6001 tccaattcca taagggtcag acagcaaatg gctttggttt tataaaccat tcagctgtgc
     6061 tgtggtactg caaatacacc catagataat gtgagcaaga aagcttggct acagccaggg
     6121 aaactgtttg tagacacttt tttgagacag tctgtgtaac ccagttcaag cccaggccta
     6181 gccttaagtt ttagatctct agcgtcaagc tcccaagtgc tggagtctgt accaccacac
     6241 cagattctta taacttttgt gttgtaaaat atcttctttt atttaaatat tgttaaaatg
     6301 taaaaattag tttttaactt acaggattta ccaaaacgtg gtagtgaatc tgatttgttc
     6361 tttgggctac tagtttgcca attcttgctc tcgagataca agaagtcaaa acttgagatt
     6421 ctcttactgt cttatacatt agatccttgt ctttagtcag agtcagctaa ctgtgattaa
     6481 aagctaagta gaactgtttc cttgtcccct aactgtttta gtctagtgct acaatgttta
     6541 acccttcatt aaatcacaga gatatggaac actaaaccct gtttttcctt tctgtttaag
     6601 ccctcatttt gtaatataga gtatagattg gtaagttggc cgccactctg agtcatcagt
     6661 tctgtccctt tactatccaa taaaactatc tatggaccaa g
//
