LOCUS       NM_177742               1850 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Mus musculus tripartite motif family-like 1 (Triml1), mRNA.
ACCESSION   NM_177742
VERSION     NM_177742.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1850)
  AUTHORS   Tian,L., Wu,X., Lin,Y., Liu,Z., Xiong,F., Han,Z., Zhou,Y., Zeng,Q.,
            Wang,Y., Deng,J. and Chen,H.
  TITLE     Characterization and potential function of a novel pre-implantation
            embryo-specific RING finger protein: TRIML1
  JOURNAL   Mol Reprod Dev 76 (7), 656-664 (2009)
   PUBMED   19156909
  REMARK    GeneRIF: Characterized TRIML1, which expresses in embryo before
            implantation; binding partner of TRIML1, Ubiquitin-specific
            protease 5 (USP5), was identified
REFERENCE   2  (bases 1 to 1850)
  AUTHORS   Sharov,A.A., Piao,Y., Matoba,R., Dudekula,D.B., Qian,Y.,
            VanBuren,V., Falco,G., Martin,P.R., Stagg,C.A., Bassey,U.C.,
            Wang,Y., Carter,M.G., Hamatani,T., Aiba,K., Akutsu,H., Sharova,L.,
            Tanaka,T.S., Kimber,W.L., Yoshikawa,T., Jaradat,S.A., Pantano,S.,
            Nagaraja,R., Boheler,K.R., Taub,D., Hodes,R.J., Longo,D.L.,
            Schlessinger,D., Keller,J., Klotz,E., Kelsoe,G., Umezawa,A.,
            Vescovi,A.L., Rossant,J., Kunath,T., Hogan,B.L., Curci,A.,
            D'Urso,M., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Transcriptome analysis of mouse stem cells and early embryos
  JOURNAL   PLoS Biol 1 (3), E74 (2003)
   PUBMED   14691545
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK077092.1.
            
            On May 7, 2009 this sequence version replaced NM_177742.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077092.1, BC141202.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1624              AK077092.1         3-1626
            1625-1850           AK077092.1         1629-1854
FEATURES             Location/Qualifiers
     source          1..1850
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 23.89 cM"
     gene            1..1850
                     /gene="Triml1"
                     /gene_synonym="4933403D14"
                     /note="tripartite motif family-like 1"
                     /db_xref="GeneID:244448"
                     /db_xref="MGI:MGI:2687279"
     exon            1..520
                     /gene="Triml1"
                     /gene_synonym="4933403D14"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..1507
                     /gene="Triml1"
                     /gene_synonym="4933403D14"
                     /EC_number="2.3.2.27"
                     /note="tripartite motif family-like protein 1; RING-type
                     E3 ubiquitin transferase TRIML1"
                     /codon_start=1
                     /product="probable E3 ubiquitin-protein ligase TRIML1"
                     /protein_id="NP_808410.1"
                     /db_xref="CCDS:CCDS22266.1"
                     /db_xref="GeneID:244448"
                     /db_xref="MGI:MGI:2687279"
                     /translation="MSNHEKMSTTDLMENLREELTCFICLDYFSSPVTTECGHSFCLM
                     CLLKSWEEHNTPLSCPECWRTLGAPHFQANERLGRLANIGRQLRSQVLQSEDEQSICG
                     RMPGPSWVFSDDEQSVINVSPPSQGTNKACFSSEAEEQHKEKLQDIINILRKKKKEVQ
                     AILNHEKERVMLCKEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEREEKANMKKLR
                     ENEIQLTQQIRRLGKMIGRIESTCQNLTLESFEEVKGAMDRYESLLFQSPETTITELS
                     LCHITGMREMLRKFSTDITLDPATANAYLLLSEDLKSVRYGGTRQQLPDNPERFDQSA
                     TVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSVNRKGNLPKPPGDLFSLIGLKIGDD
                     YSLWVSSPLKGQHVREPVHKVGVFLDYDSGHIAFYNATDESLIYSFPPTPFHEALRPI
                     FSPCLPNEGTNTDPLIICHI"
     exon            521..616
                     /gene="Triml1"
                     /gene_synonym="4933403D14"
                     /inference="alignment:Splign:2.1.0"
     exon            617..847
                     /gene="Triml1"
                     /gene_synonym="4933403D14"
                     /inference="alignment:Splign:2.1.0"
     exon            848..870
                     /gene="Triml1"
                     /gene_synonym="4933403D14"
                     /inference="alignment:Splign:2.1.0"
     exon            871..968
                     /gene="Triml1"
                     /gene_synonym="4933403D14"
                     /inference="alignment:Splign:2.1.0"
     exon            969..1850
                     /gene="Triml1"
                     /gene_synonym="4933403D14"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttcttgta ataacaacac agcacctgat catcacccag ctgtgactga agaggacttc
       61 tgtaatccca gaccagaagt gtagccttgt cctgatgtcc aaccatgaga aaatgtccac
      121 aacagatttg atggagaacc tcagggaaga gctgacctgt ttcatctgct tggattattt
      181 cagcagtcca gtgaccaccg agtgtgggca cagcttttgt ctgatgtgcc tcctcaagag
      241 ttgggaggag cacaacacac ctttatcttg tcctgaatgc tggaggactt tgggagcccc
      301 acattttcaa gccaacgagc ggctggggag actggctaat attggcagac agctgagatc
      361 gcaggtgctg cagagcgagg atgagcagag catctgtggg agaatgccag ggcctagttg
      421 ggtgttctct gacgatgagc agagtgtcat taatgtctca cctccaagtc aagggacgaa
      481 caaggcgtgt ttctcaagtg aggctgagga gcagcacaaa gaaaaactcc aagatatcat
      541 aaatatttta cggaaaaaga agaaggaagt tcaggccatc ctgaaccatg agaaggaacg
      601 agtgatgttg tgtaaggagg agacaaagac ttgtaagcag gtcgttgtgt ctgaatacat
      661 gaagatgcac cagttcctca aggaagagga acagctccag ctccagctcc tggagaggga
      721 ggagaaggcg aacatgaaga agctgaggga aaatgagatc cagctgaccc agcaaatccg
      781 ccgcctcggc aaaatgattg ggcggattga gtctacctgt cagaacttga cgttagaatc
      841 ttttgaggaa gtcaaaggag ccatggatcg gtatgagtcc ctgttgtttc agtctccaga
      901 gaccaccatc acggaactga gcctgtgtca catcactggg atgagggaga tgctgcgaaa
      961 attcagcaca gatataactc tagatccagc cacagccaat gcttacctgc ttttgtccga
     1021 agatctgaaa agtgtgcggt atggagggac caggcagcaa ttacctgaca acccagagcg
     1081 atttgatcag tctgcaactg tgttgggagc tcagatcttc acctgcggga gacactactg
     1141 ggaagtggaa gtgggaaaga agacggagtg ggaagtgggg atctgcaagg actctgtgaa
     1201 cagaaagggg aatctcccca aaccgcccgg ggacctcttc tcactcatag gcttaaaaat
     1261 tggcgacgat tacagtctct gggtttcatc tcccctgaaa gggcaacatg tccgagaacc
     1321 cgtgcataaa gttggtgtgt tcttggacta tgactctgga cacatagcct tctacaatgc
     1381 gacagatgag tccctcatct acagcttccc tccgacccct ttccatgaag ctctcagacc
     1441 tatcttttcc ccttgtcttc cgaatgaggg gacgaataca gaccctctta tcatctgcca
     1501 catctgaggg acatgccctg agccttgagc aaagacaagg ccaaggagca gcctagtcat
     1561 taacgtggtt actgtattca aagacatcac atatcagatt accccgaaca aaaaaaaaaa
     1621 aaaatcttcc ctctccccaa agactttcca caaacccagt tgtgcaatga agagcctact
     1681 aaaaatctat tcagcaccaa gaatagaaag atgataccct gcctttaacc cagttgatta
     1741 tctgagctat gctgtgtgtg ctggccactt aacaaacagc gttgtcactg tccattcttg
     1801 cctgtcaatc tgtcataggc cagttttata aatacatggc attttttttc
//
