LOCUS       NM_001042503            5197 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Mus musculus tripartite motif-containing 71 (Trim71), mRNA.
ACCESSION   NM_001042503 XM_912489 XM_980887 XM_984966
VERSION     NM_001042503.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5197)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5197)
  AUTHORS   Shi,F., Zhang,K., Cheng,Q., Che,S., Zhi,S., Yu,Z., Liu,F., Duan,F.,
            Wang,Y. and Yang,N.
  TITLE     Molecular mechanism governing RNA-binding property of mammalian
            TRIM71 protein
  JOURNAL   Sci Bull (Beijing) 69 (1), 72-81 (2024)
   PUBMED   38036331
  REMARK    GeneRIF: Molecular mechanism governing RNA-binding property of
            mammalian TRIM71 protein.
REFERENCE   3  (bases 1 to 5197)
  AUTHORS   Li,X.J., Morgan,C., Nadar-Ponniah,P.T., Kolanus,W. and
            Doetzlhofer,A.
  TITLE     TRIM71 reactivation enhances the mitotic and hair cell-forming
            potential of cochlear supporting cells
  JOURNAL   EMBO Rep 24 (9), e56562 (2023)
   PUBMED   37492931
  REMARK    GeneRIF: TRIM71 reactivation enhances the mitotic and hair
            cell-forming potential of cochlear supporting cells.
REFERENCE   4  (bases 1 to 5197)
  AUTHORS   Liu,Q., Novak,M.K., Pepin,R.M., Maschhoff,K.R. and Hu,W.
  TITLE     Different congenital hydrocephalus-associated mutations in Trim71
            impair stem cell differentiation via distinct gain-of-function
            mechanisms
  JOURNAL   PLoS Biol 21 (2), e3001947 (2023)
   PUBMED   36757932
  REMARK    GeneRIF: Different congenital hydrocephalus-associated mutations in
            Trim71 impair stem cell differentiation via distinct
            gain-of-function mechanisms.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5197)
  AUTHORS   Liu,Q., Novak,M.K., Pepin,R.M., Maschhoff,K.R., Worner,K., Chen,X.,
            Zhang,S. and Hu,W.
  TITLE     A congenital hydrocephalus-causing mutation in Trim71 induces stem
            cell defects via inhibiting Lsd1 mRNA translation
  JOURNAL   EMBO Rep 24 (2), e55843 (2023)
   PUBMED   36573342
  REMARK    GeneRIF: A congenital hydrocephalus-causing mutation in Trim71
            induces stem cell defects via inhibiting Lsd1 mRNA translation.
REFERENCE   6  (bases 1 to 5197)
  AUTHORS   Schulman,B.R., Esquela-Kerscher,A. and Slack,F.J.
  TITLE     Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125
            during mouse embryogenesis
  JOURNAL   Dev Dyn 234 (4), 1046-1054 (2005)
   PUBMED   16247770
  REMARK    GeneRIF: lin-41 is temporally regulated by miRNAs in order to
            direct key developmental events such as limb formation.
REFERENCE   7  (bases 1 to 5197)
  AUTHORS   Lancman,J.J., Caruccio,N.C., Harfe,B.D., Pasquinelli,A.E.,
            Schageman,J.J., Pertsemlidis,A. and Fallon,J.F.
  TITLE     Analysis of the regulation of lin-41 during chick and mouse limb
            development
  JOURNAL   Dev Dyn 234 (4), 948-960 (2005)
   PUBMED   16245339
  REMARK    GeneRIF: Lin-41 is genetically and biochemically downstream of both
            the Shh and Fgf signaling pathways and is expressed in three phases
            over developmental time and most notably is associated with the
            developing autopod.
REFERENCE   8  (bases 1 to 5197)
  AUTHORS   Taniwaki,T., Haruna,K., Nakamura,H., Sekimoto,T., Oike,Y.,
            Imaizumi,T., Saito,F., Muta,M., Soejima,Y., Utoh,A., Nakagata,N.,
            Araki,M., Yamamura,K. and Araki,K.
  TITLE     Characterization of an exchangeable gene trap using pU-17 carrying
            a stop codon-beta geo cassette
  JOURNAL   Dev Growth Differ 47 (3), 163-172 (2005)
   PUBMED   15840001
REFERENCE   9  (bases 1 to 5197)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 5197)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC164109.2.
            
            On Dec 12, 2009 this sequence version replaced NM_001042503.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ005956.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2065              AC164109.2         32756-34820
            2066-2233           AC164109.2         72004-72171
            2234-2368           AC164109.2         81258-81392
            2369-5197           AC164109.2         83029-85857
FEATURES             Location/Qualifiers
     source          1..5197
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 64.54 cM"
     gene            1..5197
                     /gene="Trim71"
                     /gene_synonym="2610206G21Rik; 636931; Gm1127; lin-41;
                     Lin41; mlin-41; mLin41"
                     /note="tripartite motif-containing 71"
                     /db_xref="GeneID:636931"
                     /db_xref="MGI:MGI:2685973"
     exon            1..2065
                     /gene="Trim71"
                     /gene_synonym="2610206G21Rik; 636931; Gm1127; lin-41;
                     Lin41; mlin-41; mLin41"
                     /inference="alignment:Splign:2.1.0"
     exon            2066..2233
                     /gene="Trim71"
                     /gene_synonym="2610206G21Rik; 636931; Gm1127; lin-41;
                     Lin41; mlin-41; mLin41"
                     /inference="alignment:Splign:2.1.0"
     exon            2234..2368
                     /gene="Trim71"
                     /gene_synonym="2610206G21Rik; 636931; Gm1127; lin-41;
                     Lin41; mlin-41; mLin41"
                     /inference="alignment:Splign:2.1.0"
     exon            2369..5197
                     /gene="Trim71"
                     /gene_synonym="2610206G21Rik; 636931; Gm1127; lin-41;
                     Lin41; mlin-41; mLin41"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      4255
                     /gene="Trim71"
                     /gene_synonym="2610206G21Rik; 636931; Gm1127; lin-41;
                     Lin41; mlin-41; mLin41"
     polyA_site      4263
                     /gene="Trim71"
                     /gene_synonym="2610206G21Rik; 636931; Gm1127; lin-41;
                     Lin41; mlin-41; mLin41"
                     /note="major polyA site"
ORIGIN      
        1 gtttgctcct ttggagatta aaaggattcc gaattccgat cagtcccaat aacccgcgtt
       61 ctgagaggcg gcaaagcgga gaaagaaggg ggacacgcgc acgcacacag cccctcgttc
      121 gggggagtcg tgcaaaataa agcccaaagc aacccaggac accagggcat cgggagagcc
      181 tgagcccggt aggcgcagcg cagccggggc cacccgcatc cccgctcggc gaatcgttcg
      241 taggaggatg acgcaggcgg gagccgcggg cggcgttggc cacgcggctc ccgaagtggc
      301 cgcgcgggtc cctcgcgtac tcctctgatt cgagcaagcc cgggagggag actcggttcc
      361 cgaggctccg ggattgaagg ggggacccaa gcgagggtga aatggcccga tgacaaagga
      421 aatgtgatcc tccttcgctg cccaggtttc ggagaggacg gccgtgagga ggaggggcgc
      481 gcggctcgcg cggaacgcgg atagcattgc acgacggccc cgcgcggagc gggcggcccg
      541 tacatccaat atcttcccgc cgatgaataa ttcagggcgg cccgcgggga cctgcggccc
      601 cgcgccgcgg agcgcctgag gccggagaag ggtcggagcg cgcgctagag agcgagccag
      661 gaggccggag gacacgcggg cgccgggccg cgtggggcgc gcgcgcgtgt gagcgcatag
      721 agaccgcggc ccggcagggc tgcgcacggg cgcggagcgt gtggggcgcg cgtgcgtact
      781 tggcacgcgt gcttccgcgg gccgggggcc cccgcacgag gcgcagctgc gcgcccgagc
      841 cgaccgcgcc gcgggggagg ctgcgcctcg gccgccacgc aggagctcct gccgccgcgt
      901 catgcggcgg ggcggccggc ggcgcgcgcg gggacttgga ctgctgcgac tcccggacgt
      961 tttcccctcc ctccaggagg ctcaattcat ttagccggag ggcaaggaaa aaaaaaaaac
     1021 aacacaagca agactcgttg ggaccaaatt ggtttgcgcc gcggggaccg gattccacgg
     1081 cggactttga gacttgtgcg ggcgctcgtt tgctgaggag tagcagtgca aacccgccct
     1141 gccgaggtgg cccaggggtc gcctccaccg cgtcctcgat gcgctctgct gagtgagccg
     1201 cgcgccctca tcctcctcgc cgcgcgccct ctgccctcca gcccgcctgc aaatggcttc
     1261 gttcccggag accgacttcc agatctgcct gctgtgcaag gagatgtgcg gctcgcccgc
     1321 gccgctctcc tccaactcgt ccgcctcgtc gtcgtcctcg cagacttcca cgtcgtcggc
     1381 gggcggcggc ggccccgggg cggcggcgcg gcgtcttcac gtcttgccct gcctgcacgc
     1441 cttctgccgg ccgtgcctcg aggcgcaccg gctgcccgct cccggaggcg cgggccccgc
     1501 cgaggcgctg aagctgcgct gccccgtatg tgaccagaag gtggtcctgg ccgaggcggc
     1561 gggcatggac gcgctgccat cctccgcctt cctgctcagc aacctgctgg acgccgtggt
     1621 ggccaccgcc gaagagccgc cgcccaagaa cgggcgcgcg ggcggcggcc ccgggggcgc
     1681 gggcggccac agcaaccacc ggcaccatgc gcaccacccg gcccagcgcg ccgccgctcc
     1741 agcgccgcag ccgccgcccg gcccggccgc ctcccccggg tcgctgctga tgcgccggcc
     1801 gcacggctgc agctcctgcg acgagggcaa cgccgcctcg tcgcgctgcc tcgactgcca
     1861 ggaacacctg tgcgacaact gtgtccgcgc gcaccagcgc gtccgcctca ccaaggacca
     1921 ttacatcgag cgcggccctc cggggcctgc ggccgcctcc gcggcacagc agctggggct
     1981 cgggccgccc ttcgcgggcg cgcccttctc cattctctcg gtgttcccgg agcgcctcgg
     2041 cttctgccag caccacgacg atgaggtcct gcatctctac tgtgacacct gctctgtccc
     2101 catctgcaga gagtgcacgc tgggccgcca cggtggccac agcttcgcct acctccagga
     2161 tgccctgcag gactctcggg cactcaccat ccagctgctg gctgatgccc agcagggccg
     2221 ccaggctctc cagctgagca tcgagcaggc ccagactgtg gcagaacagg tggagatgaa
     2281 ggcgaaggtg gtccagtctg aggtcaaggc cgtcacagct cgccacaaga aggccctgga
     2341 ggatcgggag tgtgagctgt tgtggaaggt ggagaagatc cggcaggtga aggcgaagtc
     2401 tctgttcctg caggtggaga agctgcggca gagtctcagc aagctggaga gcaccatcag
     2461 cgccgtgcag caggtcctgg aagagggccg cgccctggac atcctgctgg cccgagaccg
     2521 gatgctggcc caggtgcagg agctcaagac catccgaggc ctcctgcagc cccaagaaga
     2581 tgaccgcatt atgttcacgc cccctgacca ggccctgtac ctcgccctca agtctattgg
     2641 ctttgtcagc agcggggcct tcgccccgct cacgaaggct acaggagatg gcatcaagcg
     2701 tgcccttcag gggaaggtgg cctctttcac tgtcatgggc tacgaccacg atggtgagcc
     2761 ccgccattcg ggaggtgacc tgatgtcagt tgtggtcctc ggccccgacg gaaacctgtt
     2821 tggtgcagaa gtgagcgacc agcagaatgg tacttacata gtgagctaca ggccccagct
     2881 tgagggtgag cacttggtgt cggtgacatt gtacaatcag catatagaga acagcccctt
     2941 caaggtcgtg gtcaagtcgg gccgcagcta cgtgggcatc gggctccccg ggctgagctt
     3001 cggcagtgaa ggtgacgggg agggcaagct ctgcaggccc tggggcgtga gtgttgataa
     3061 ggagggtttc atcatagtgg ctgaccgaag caataacaga atccaggtgt ttaagccctg
     3121 tggttccttc caccacaagt ttggtaccct tgggtctcgt cctgggcagt ttgaccgacc
     3181 ggctggggtg gcttgtgacg cctcccgcag gatcatagtg gccgacaaag acaatcatcg
     3241 cattcagatc ttcaccttcg agggccagtt ccttcttaag tttggtgaga aaggcaccaa
     3301 gaacgggcag tttaactacc cgtgggatgt agcagtgaat tctgagggca agatcctcgt
     3361 ttcagacacc cggaatcatc gcatccagtt gttcggaccg gacggggtct tcctgaacaa
     3421 gtacggcttc gagggatctc tctggaagca cttcgactct ccacggggcg tggctttcaa
     3481 caatgaaggt cacctggtag tcaccgactt caacaaccac cggcttctgg ttattcaccc
     3541 tgattgccaa tctgcccgct tcttgggttc ggagggctcg ggcaatgggc agttcctgcg
     3601 accacagggt gtggctgtgg accaggaagg gagaatcatc gtagccgatt ccagaaatca
     3661 ccgcgtgcag atgtttgagg ccaatggcag cttcctgtgc aagtttggtg ctcaagggag
     3721 tggcttcggg cagatggacc gcccctcagg tatcgcggtc accccggatg gattgatcgt
     3781 cgtggtggac tttggcaaca atcgaatcct catcttctaa ttgtgtcttc tggggttttc
     3841 tgtgtttagg gtgtgcatgt gtgtgtctct catttttgaa tttcaaagaa gaaatcgtct
     3901 cagggatatt tctttttctt tttccccccc tttattttta ttattttttt ttttttaaga
     3961 acaaaagtac aacattgcct aagtcctacc tcagcttaaa tttttttttt tttttttttt
     4021 ttacagatga atgtaattct cctctgtgca gggcttgagc ctgtgaagtg ataatttcta
     4081 tctacctcaa ctctttgcat ttccctctct ggcaagcctc ttggctcaca tcctcttccc
     4141 tcctgaaggc ctaggaggca caggacagcg gtcctgcaac cttgagggca ctggaagcat
     4201 atggtggggt gcatgcattt tgtagattga gccaaggaaa cccaaaaact actaagtaaa
     4261 aaagagaagt ataagatgtt ggaaagatag gatttaaaat tcataattgt agtgtatttg
     4321 tgttcttgag aatactgtgt ttatgtgggg ttaggttgtg tgtggtttgc tcttttcttt
     4381 tttatcgatg caacagggct tttctctgtt tacctcagtg tgtctgacat ctcatcccta
     4441 ggagatatgg ctgtggcttg ctagcctaga aaagcagacc attcatattt tcgggtgtct
     4501 catctttgta tctggtaaag aagggtgggt gtgtgggagt gtgtgtgtgc acacgcgtgc
     4561 atgtttgtgt ttcaaagcca tctttgcttg aggagaaaag ctggacttga cacaagacat
     4621 cccaagcaaa tttcttccca gtttgctaag aaactcgatt tagctcagga ctctaggttg
     4681 aaagtgttcg caaaggttac gtgtctgtgt ttttgttgtt tgttataaag acttaggtat
     4741 aagaaaataa gttaaccttg ttctcagaga gagaggggct tttcagatgt ggaccagggt
     4801 gccacagaag tggggggtgc tggagaagtg aggcaccccc acatcaggga ctgttcagga
     4861 gggcggggga cctcgtctct atgtgtgagg gtgtggtagg caaagggata gctttgattt
     4921 gagaagcaca atgttttttc ctgctttgga agttcaggga atgtagaaga ttgtctgact
     4981 ggtgggagca cctcactccc taacccttgg ctcaggtctg tttctcagga accttcccta
     5041 agtctgagtg gaggcagacc tcaaggttaa cacaaagccc cgttcctccc ccaaaggcct
     5101 ttgaatgtaa aggatttaca aaccaaacca cccaacagga agtgtaggac acagtatatg
     5161 tctttttttt tttttaattt tattttattt aaaaaaa
//
