LOCUS       NM_001170912            9192 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Mus musculus tripartite motif-containing 66 (Trim66), transcript
            variant 1, mRNA.
ACCESSION   NM_001170912
VERSION     NM_001170912.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9192)
  AUTHORS   Mielnicka,M., Tabaro,F., Sureka,R., Acurzio,B., Paoletti,R.,
            Scavizzi,F., Raspa,M., Crevenna,A.H., Lapouge,K., Remans,K. and
            Boulard,M.
  TITLE     Trim66's paternal deficiency causes intrauterine overgrowth
  JOURNAL   Life Sci Alliance 7 (7), e202302512 (2024)
   PUBMED   38719749
  REMARK    GeneRIF: Trim66's paternal deficiency causes intrauterine
            overgrowth.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9192)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 9192)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9192)
  AUTHORS   Wajapeyee,N., Malonia,S.K., Palakurthy,R.K. and Green,M.R.
  TITLE     Oncogenic RAS directs silencing of tumor suppressor genes through
            ordered recruitment of transcriptional repressors
  JOURNAL   Genes Dev 27 (20), 2221-2226 (2013)
   PUBMED   24105743
REFERENCE   5  (bases 1 to 9192)
  AUTHORS   Ryder,E., Gleeson,D., Sethi,D., Vyas,S., Miklejewska,E., Dalvi,P.,
            Habib,B., Cook,R., Hardy,M., Jhaveri,K., Bottomley,J.,
            Wardle-Jones,H., Bussell,J.N., Houghton,R., Salisbury,J.,
            Skarnes,W.C. and Ramirez-Solis,R.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Molecular characterization of mutant mouse strains generated from
            the EUCOMM/KOMP-CSD ES cell resource
  JOURNAL   Mamm Genome 24 (7-8), 286-294 (2013)
   PUBMED   23912999
REFERENCE   6  (bases 1 to 9192)
  AUTHORS   Khetchoumian,K., Teletin,M., Mark,M., Lerouge,T., Cervino,M.,
            Oulad-Abdelghani,M., Chambon,P. and Losson,R.
  TITLE     TIF1delta, a novel HP1-interacting member of the transcriptional
            intermediary factor 1 (TIF1) family expressed by elongating
            spermatids
  JOURNAL   J Biol Chem 279 (46), 48329-48341 (2004)
   PUBMED   15322135
  REMARK    GeneRIF: Data suggest a role for transcriptional intermediary
            factor 1 (TIF1) delta in heterochromatin-mediated gene silencing
            during postmeiotic phases of spermatogenesis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124457.4.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY572454.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-394               AC124457.4         114325-114718       c
            395-498             AC124457.4         92631-92734         c
            499-646             AC124457.4         91162-91309         c
            647-779             AC124457.4         90222-90354         c
            780-896             AC124457.4         89616-89732         c
            897-1011            AC124457.4         88467-88581         c
            1012-1158           AC124457.4         87510-87656         c
            1159-1276           AC124457.4         84222-84339         c
            1277-2184           AC124457.4         81636-82543         c
            2185-2346           AC124457.4         78818-78979         c
            2347-2868           AC124457.4         67077-67598         c
            2869-3061           AC124457.4         66742-66934         c
            3062-3122           AC124457.4         65325-65385         c
            3123-3297           AC124457.4         64695-64869         c
            3298-3584           AC124457.4         64132-64418         c
            3585-3711           AC124457.4         63630-63756         c
            3712-3786           AC124457.4         62646-62720         c
            3787-3939           AC124457.4         62216-62368         c
            3940-4158           AC124457.4         61611-61829         c
            4159-9192           AC124457.4         55585-60618         c
FEATURES             Location/Qualifiers
     source          1..9192
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 57.21 cM"
     gene            1..9192
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /note="tripartite motif-containing 66"
                     /db_xref="GeneID:330627"
                     /db_xref="MGI:MGI:2152406"
     exon            1..394
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..4218
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /note="isoform 1 is encoded by transcript variant 1;
                     tripartite motif-containing protein 66; TIF1delta;
                     transcriptional intermediary factor 1 delta"
                     /codon_start=1
                     /product="tripartite motif-containing protein 66 isoform
                     1"
                     /protein_id="NP_001164383.1"
                     /db_xref="CCDS:CCDS52360.1"
                     /db_xref="GeneID:330627"
                     /db_xref="MGI:MGI:2152406"
                     /translation="MSPGLPVSIPSQPHCSTDERVEALAPTCSMCGRDLQAEGSRLLP
                     CQHLLCKDCYQGFMQELGHATRAYPGKLISCPGCQRVYLTRDVTEHIFLQCFSPVKPT
                     MARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHVPAPGGPLFARAQKGSSGVNGGS
                     GDFALYCPLHTQEVLKLFCETCDVLTCHSCLMVEHKEHRCRHVEEVLQNQRMLLESVT
                     SQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELE
                     GITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKSSVPFLFSKELIVFQMQRLL
                     ETRCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGGQLTRADAAAASYGSLQGQPS
                     FYQSHQAPMAQQEALSHPSHKFQSPALCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHS
                     FRQPSEMVPHQLGSLQCSTLLPREKELACSPHPPKLMQPWLEPQPPAEQESTSQRPGP
                     QLVSQPVCIVPPQDVQPGAHAQPTIQTPSIQVQLGHHQKLKLSHFQQQPQQQPPPPPP
                     PPPPPQHAPPPLPPSQHLASSQHESPPGPACSQNVDIMHHKFELEEMQKDLELLLQAQ
                     QPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETLQVTEEPPAPEGPKPAL
                     PVDKNTAAPLPQTSGEETPHSVPPVDGTSQHSSPNVVRKHATSVSIMGFSNTVEMELS
                     STRLARTIEPQIHRVSSLTAAPTHTIPSLLSGPPQTVSSLMSVSNHAMPSLTASHLQP
                     VPNLVRGTFQSTSNLRGDSSQAITGLASNHSQAGPSLMSGHTQAAPSLATCPLQGMPP
                     VSDVHVEPRSVSSPGSGPAAESLGTRDGAESSLGNALCKMESEDCTRFSDSVGQGPTA
                     SSLDGPKDLAIPSELEEPINLSVKKPFLAPVINTSTALQQYRNPKEYENFEQGALELD
                     TKENSDIRAISSEPKIPYVRLERLKICAASSGEMPVFKLKPQKNSQDGNFLLVIECGT
                     ESSSMSIKVSQNSLPDASQGPGLGGRKVTVTSLTGQQPQEVESTSEEHRLIPRAPGAK
                     KNTPAPIENEDFCAVCINGGELLCCDRCPKVYHLSCHVPALLSFPGGEWVCTLCRSLT
                     QPEMEYDCENARYGHPGVRVLPGLSMYDQKKCEKLVLSLCCNSLSLPFHEPVSPLARH
                     YYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGR
                     CLEVFFEGWLKEIYPDKCFAQPQQEDSDSEDVSGESGCSTPQGFPWPPYMQEGIQPKR
                     RRRHMENEKTKRVSFRLANSISQV"
     exon            395..498
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            499..646
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            647..779
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            780..896
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            897..1011
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1158
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1276
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..2184
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            2185..2346
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            2347..2868
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            2869..3061
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            3062..3122
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            3123..3297
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            3298..3584
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            3585..3711
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            3712..3786
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            3787..3939
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            3940..4158
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     exon            4159..9192
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4409..4414
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /note="hexamer: AGTAAA"
     polyA_site      4422
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /note="major polyA site"
     regulatory      9162..9167
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /note="hexamer: AATAAA"
     polyA_site      9192
                     /gene="Trim66"
                     /gene_synonym="Kiaa0298-hp; Tif1d"
                     /note="major polyA site"
ORIGIN      
        1 ataacttgga cctcggagac tctctcttct tacctgttca agaactgctc ccatcccaaa
       61 gaataagtga agtccctctg ctctgtgcct cacttgcagg gagaggagct tgctcgcgct
      121 acacgatgcc tcatccccga agatgtcagc agaaaagctg aagccccaaa ctcaggtgca
      181 gacatgagcc caggcctgcc tgtgagcatt ccaagtcagc cacactgctc tacagatgaa
      241 cgcgtggagg ctctggcacc gacctgctct atgtgtggac gggacctaca agctgagggc
      301 tcccggcttt taccgtgcca acatctgctc tgtaaggatt gctaccaggg cttcatgcag
      361 gagctagggc atgctaccag ggcttaccca ggtaagctca tctcctgtcc tggatgtcag
      421 cgtgtctatc ttaccagaga tgtaactgaa catattttcc ttcagtgctt ttctcctgtg
      481 aaacccacta tggccaggaa ctgctctgag tgcaaggaga agcgggcagc acacatcctc
      541 tgcacatact gcaaccgctg gctgtgcagc tcctgcacag aggagcaccg gcatgtccca
      601 gccccggggg gcccactctt tgcacgggca cagaagggat cctcaggggt gaatggtggc
      661 tctggggact ttgccttgta ctgccctctg cacacacagg aagtgctcaa gcttttctgc
      721 gagacgtgcg atgtactcac ctgccacagc tgcctgatgg tggagcacaa agagcacaga
      781 tgcaggcacg tggaagaagt tctacaaaac cagaggatgc tcctggagag tgtgacttcc
      841 caggtggcac ataagaaatc cagcctacag acatctgcaa agcaaatcga ggacagaatt
      901 tttgaagtga agcatcagca ccggaaggtg gagaaccaga ttaaaatggc caagatggtc
      961 ctcatgaacg agttgaacaa gcaagccaac gggctcatag aggagcttga gggcatcact
     1021 aatgagagaa agcgaaagct ggagcagcag ctgcagagca tcatggttct caaccggcag
     1081 tttgaacatg tgcagaattt catcaactgg gctgtctgca gcaaaagcag cgtccctttc
     1141 cttttcagca aagagctgat tgtgtttcag atgcagcggt tgctggagac gagatgtaac
     1201 acagatcctg gctctccttg gagtatcaga ttcacctggg agcccaactt ctggaccaag
     1261 cagctggctt cccttggctg cataaccact gaaggtggac agctgacccg ggcagatgct
     1321 gcagctgcct cttatgggag tttacagggg cagccatctt tttatcagag ccaccaggcc
     1381 cccatggctc agcaggaggc actcagccac ccctcacaca agttccagtc tccagcactg
     1441 tgttcctcgt ctgtctgctg ctcccactgc tctccagtct cgccttccct caaaggtcaa
     1501 gtccctccac ccagcatcca cccggctcac agtttccgac agccttctga aatggtgccc
     1561 caccagctgg ggtcactgca gtgttctacc ctgctgccca gggagaaaga gctggcctgc
     1621 agtcctcatc cacccaaact gatgcagccc tggttggaac cacaacctcc tgcagaacag
     1681 gagagtacat cccagcggcc aggaccgcaa ctggtttccc agcctgtgtg catcgtccct
     1741 ccgcaagatg tgcagccagg agcccatgcc cagcccacca tacagacacc ctccatccaa
     1801 gttcagctgg gccaccatca gaagctaaag ctcagccact ttcagcagca gccgcagcag
     1861 cagccacccc caccaccgcc acctccccca cccccccagc atgcacctcc acccttgcct
     1921 ccatcccagc acctggcttc cagtcagcac gagagccctc ctgggcctgc ctgttcgcag
     1981 aatgtggaca ttatgcacca caagtttgag ctggaggaga tgcagaagga cttggagctt
     2041 ctcctgcagg cccagcagcc tagcctgcag ttgagtcaga ccaagtctcc tcagcatctt
     2101 cagcaaacca tcgtggggca gatcaactac atcgtgaggc agccagcacc cgtgcagtcc
     2161 cagagccagg aggagaccct gcaggttaca gaggagccac cagcacctga gggcccaaag
     2221 ccagctctac ctgttgacaa gaacactgct gctcccttgc cccagacatc tggggaggaa
     2281 acgcctcaca gtgtccctcc agtggatggc acctcccagc actcttctcc aaatgtggtg
     2341 agaaagcacg ccacctcagt gagcatcatg ggcttttcca acactgtgga gatggagttg
     2401 tcatctacca ggctggcgag gaccatagag ccacagatac acagggtgag cagcctgaca
     2461 gctgccccca cccacacaat tccgagcttg ctgagtggcc caccacaaac tgtgtccagc
     2521 ctgatgagtg tttcaaacca tgccatgcca agcctgacag ccagtcacct gcagcccgtg
     2581 ccaaaccttg tgcgtggcac attccagtcc acgtcgaacc tgaggggtga ttcctctcaa
     2641 gccatcacag gcctggcaag taatcactca caagctgggc ccagcctaat gtctgggcac
     2701 acccaggctg cgccgagtct ggccacttgt cctctgcagg gaatgccacc ggtttctgat
     2761 gtgcatgtgg agccgagatc cgtatccagt cctgggtctg gcccagctgc agaaagcctg
     2821 ggtaccaggg atggggctga gtcctccctg gggaatgcct tgtgtaagat ggaaagtgag
     2881 gattgtaccc gtttctcaga ctcagtagga caaggcccta cagcctccag tctggatggt
     2941 cccaaggatt tggctattcc ctcagaactg gaggaaccaa ttaacctctc tgtgaaaaaa
     3001 cctttcctgg caccagtgat caacacatcc actgctctgc aacagtaccg gaatccaaaa
     3061 gaatatgaga attttgaaca aggagcccta gagctggata caaaggagaa ttcagacatc
     3121 agagctatca gtagtgagcc caagatcccc tacgtgcgac tggagcggct caagatctgt
     3181 gctgcctcat caggagagat gcctgtgttt aagctgaagc cccagaaaaa tagccaggac
     3241 ggaaacttcc tcctggtgat tgagtgtggc actgagtcct ccagcatgtc cattaaggtc
     3301 agccagaaca gcctgcctga tgccagccag ggcccaggtc ttgggggaag aaaggtcact
     3361 gtcacatctc tgactgggca gcagccacaa gaggtggaga gcacatctga ggaacacaga
     3421 ctcatccccc gagctccagg agccaagaag aacaccccgg cccccataga gaatgaggac
     3481 ttctgtgcgg tgtgcatcaa cggtggggag ctgctatgct gtgaccgctg ccccaaagtg
     3541 tatcaccttt cctgccacgt gccagccttg ctcagcttcc cagggggaga atgggtgtgc
     3601 accctgtgcc gcagcctgac gcagcctgag atggagtacg actgtgagaa cgcgcgctac
     3661 ggtcaccctg gagtgcgggt acttcccggc ctgagcatgt atgaccagaa gaagtgtgag
     3721 aagctggtcc tgtccctgtg ctgcaacagc ctcagcctgc ccttccatga accagtcagc
     3781 cctctggcca ggcattatta ccagattatc aagaggccca tggacctgtc aatcatccgg
     3841 aggaaactgc aaaagaagga cccagctcat tacactactc cagaggaagt ggtgtcagat
     3901 gtacgcctca tgttctggaa ctgtgctaag ttcaattatc ctgactcgga ggttgcagag
     3961 gctggccgct gtctggaagt gttctttgaa ggctggctaa aggagatcta cccagacaaa
     4021 tgctttgccc agccccagca agaggattca gactctgagg acgtatctgg cgagagtggc
     4081 tgttccactc ctcagggctt cccatggcct ccctacatgc aggaaggcat ccagcccaag
     4141 aggcgacggc ggcatatgga gaatgagaag acaaagagag tgtcgtttcg tctggccaac
     4201 agcatctcgc aggtgtgaga gctggaagga gatggggcac gctggtggct gatgtccctg
     4261 tccttgagac catccctccc catccttcag cttatcctct tcagaacgtg gctgtgagat
     4321 gagtcttgtt gagcgtgcag cgctcccttc atcattagca tctccagtgt ttatttggga
     4381 gccatagtgc atccaccata aagatttcag taaaacaggg aagagggagg tgttcctcat
     4441 tgccagagta accggacata gaggttttgt gcctcttcgg gctcaggagg acctggcttt
     4501 cttgctgagc tctctcagct gagtggagca cactcggctc acctctctgc agccagggct
     4561 caggaacacc ttgtgtattt gaactcctgg cttagacacg ggtacaagaa aggaagtgag
     4621 gtttggatat atggcaggcc tgtggtccct gtcccagcac agccaaagat tgtcactgtt
     4681 tgcctttgct cgtcctgttg ggacagaggt gtctgccacc ggcagaataa tggaggcttc
     4741 tcgaggccct aggtctcaat cggtgcctat ttgggttcta acggttttca gggtatttgc
     4801 ttttcatgtc ccctttcctg agtaggactt atgtggtcac tgtgaaatgc tgtgtgtggt
     4861 ttggtactct tggctgagct gggtggcagt gcaaagatca gtttccactc acacccagga
     4921 gatgccagct tcagagtctg tccctctgtg tcctaactct gggataataa cactccagag
     4981 cctgccttcc cagaagtcac tggtatgtgt gccagtggct cttccttgat ttcagacatc
     5041 tgcatcttga gttccacttg ggactaatgt gacatgatgt ctgctgcagg aactgaggtc
     5101 cctggcaagg atgacccaca gccagtgcag agtgtcaggc ctctcctgcc tacgattcta
     5161 gatctctact tttttcactc agccaaagat cagaactgtg gccatgatgc tcacagcccg
     5221 gaagcaggca acactgtcac cctttagtgt tggaacttgg agaaggctac agtgactggt
     5281 aggagtctgc tgaggtgtta gtaggctaag ggtggagaag gggaaaattg ggaggtgaga
     5341 agccttaggt gactctgagg ttacatcagg gttgtagtcc tcacagaatg cagaaaggcc
     5401 cttcatggga atggggtggt ggcaacagag ctacaggcca catagtggaa ggatcactac
     5461 agtataggca gggcgtttgt gaggacgcct ctgagacaca tacagggaca ggcttcttcg
     5521 aaagcaaggg cttggctgag gaaggacctg tcgactgtac tgctgatcga gcgacaggcc
     5581 tggcatttca gtggcctggt cctgaggcat ggcatggctg atttcagggg acgcttgggt
     5641 cgtggctttg tttttgtgaa gaggtgcagt ttaaggaagt gctttttcgt agagcctttg
     5701 ctaggaagca attttctttt taccaaaaac cgtcttcttt gcccgtgagt cagtaagagc
     5761 acttgatccc ttctccattg ggctgagggg gcttcttccc tttgaagcaa gccctgccca
     5821 ctgtcttgtc atcagcagtg ctgctgccga gctctccgaa gtagatgggc ttccataccc
     5881 tgctgtctag ttccaggcag cagaaccttt acttcactct tagccaggta accctgaaag
     5941 cagtcttcgc tccttgtgtt cacaaagttt ttgggttggg gcttaggctg cttctctttt
     6001 gagttttgca tctttctctc tgattggtct gatgaggttc cttctgttct gaccttccta
     6061 attcctgttt atgggcatct ttccttttgt ggcctggatt cctactatag tcttcatggt
     6121 gtttggcact ggaaagccac cgaacactgt gatagcttga aacctaacag cctttcctgg
     6181 accagctgga gactgtgacc ataaaaatgg aaatgcctgg ttcaaagcat gggttctcct
     6241 ctcttggtac agttcatagc ttgagtgtgt cctgttagag caaggaccag cttctgggcc
     6301 cagagatctt agacatgcag caggcacggc tctgttccct ggctgtgata gggcccctct
     6361 gtggcgagac actccctctg ggcgtctgag cagggcagac agagaagagg gatgcctttt
     6421 ttctttaagg ctgtgaagct ctggtctatc attcctttcc tgtactggtt agtctgtggg
     6481 atttctcctg ggaccaagtt ttaaaagtca tgttagattt tttgtttttt gttttttgtt
     6541 ttttgcatgc agaaaacaaa actgaaagtt aaaaaaaatt aacaacaaaa gcaatcacct
     6601 gttcactaag taacttgtgc tcattttcat tggatcctgc agtgactcat ttccatatgg
     6661 tcgcattgta aagccagcta agtcaaagtc aggcaatggg aatgcactga gttctggtta
     6721 ttatactgtt ctgtgcggcc ctagaagata agaaacttgt ttctggctgt gctgagaaat
     6781 gcaatagtag ggtggctttg ggggacacca aggggatttt agtacaaaga ttgatacaaa
     6841 atatgggtat tttgatcctc cagaattcta gcaacaggta catgcctgct gcaggaatct
     6901 tacagaatgg cagctactgg gtcctccttg cacattgctc catgggagac atggttggaa
     6961 agtcagagaa tgttggctcc tgtccctagt ttagccacag gtctttgtgt gcctcgtaat
     7021 atctaggtcc ccctttttgc tgggttgtgc tccacttcca tccctactgc actggtcacc
     7081 tactgaagca cttctgagct gaggagttgt ccctgtggtc cctcttctcc agtccactca
     7141 ctcccgagca cctgccctct ccctttgccc atcccatggc tacatctccc agactttcag
     7201 tcttatctag gatcctctcc tcttcccagc ctgaacccag gccccaccac atggttctta
     7261 ttagcatctc aaactttcct aacctttcca acttccagtt tctccatttt ccacatcagc
     7321 ctgatttctg ctttttgttt ttgtttttgt tcttctaagc atggcaggtt tggagctgca
     7381 gcctcagtat tgattggaaa ttcttgaact tggtattatg tgcttcggat ctatgtccct
     7441 catctttgtt gttagccaat gacagctcac catctgtttc actgaagaga gctcatgggc
     7501 aagggcttcc tgccccctgc ctttcttcct gctgtcctgt gtgtgtatgc catctccttt
     7561 ccttccctgc tcttctggtt ctgtgttttc tgatccgggc tatgttctct aaggctctgt
     7621 ttttcactcc caggactctg taggctctct ccattgctta cctctctcca cacagcctaa
     7681 caaaggtctc tcaagattaa agcaaaactg tcacgtctgt gtcatggacc ttttcccctg
     7741 cccattattc ttcatttaaa ataaaccatt tgactgagtg tgatggcata catctttatt
     7801 cttagcactt gggagttcaa ggtcagcttg gtctacatgt ggctcaccca gggctacatg
     7861 gtaagaccct ggctcggaca agagagaata cttttctttg attcttcttc ctcttcggtc
     7921 ctctgtaggt tttcatgaga gtgaccacaa gctaccaaat gacatgcctt tcacttctct
     7981 gctgcctcga gctcctcatg gcgtctcacc agcccatctt tcccctgtgc agctctctct
     8041 tcaccgtctt tcagggtatc cgatgttgct acattagctt tatctcagcc actgaggccg
     8101 tgcttgctgg aaacctagac agagggatgt gcctggctgt catcattttc tcctcctcag
     8161 ggcctgggtg agcaagaaga atcatagttg ctcctgattt ttcctctctg tttttcatga
     8221 atcccttctt cctggatttg gttctcctct tgtgagcttg ttcttcgtca gtgaatcctt
     8281 ccctctgttg ttcccaggag acacagagag acacaccagt gtgttaagag cccccatgtc
     8341 agtcagccta ggtgggagct ggattttgta gcatgcaacc tgctgtctgg ctcagctggg
     8401 aatccacact ggtggacagc tcaccattat gatctgtacc agttggtacc tgccttggtc
     8461 agcagggagc tgaggatcat aggaaggcat gcttccatgc atggttcagt atagtctcag
     8521 cagggtgggg tctgttccta tgaccttcct gagggagcag gagactgagc agtgttgtga
     8581 ttcctcacct gagctgagcc tggctcaggt agactcctcc cacaggtctt tcccatttgt
     8641 gctgatcatt ccacatctgc ttgctttaga tgttacaggg cttgaggcac atggtagttg
     8701 ctttcttgga ggtactgtag aaggacatct ggcttgagtt ttggaatctg ttttggcatt
     8761 gtcaatgatg ggaggtatga ccttgggtat agttccttca tttataaagt taggagtctc
     8821 tcagagattc tgtagttcta aagatgataa ctatgattct aactctgaag cccagaccac
     8881 atagggtcag aggaaccctg ggagtgggga cacagctaga gaagtcccaa ccaggcaggg
     8941 taacaaactc tacaggccaa attgcgctgc tttggagaaa gtcttccctg gctggcgctg
     9001 cttcattgag ccatatgccc atacctcaag ctggacactt cttggtgtct gcacacgttc
     9061 ctcctagatg tggtcatatg atccaaagtg gctaggggca caaggaaagg atttaagggg
     9121 aagcaaaatt gattttaaat agacctacac attcaaaatt aaataaaaaa taacactttc
     9181 ctttaccagc aa
//
