LOCUS       NM_001177551            2156 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus tripartite motif-containing 61 (Trim61), transcript
            variant 2, mRNA.
ACCESSION   NM_001177551
VERSION     NM_001177551.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2156)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2156)
  AUTHORS   Yu,C., Ji,S.Y., Dang,Y.J., Sha,Q.Q., Yuan,Y.F., Zhou,J.J.,
            Yan,L.Y., Qiao,J., Tang,F. and Fan,H.Y.
  TITLE     Oocyte-expressed yes-associated protein is a key activator of the
            early zygotic genome in mouse
  JOURNAL   Cell Res 26 (3), 275-287 (2016)
   PUBMED   26902285
REFERENCE   3  (bases 1 to 2156)
  AUTHORS   Huang,C.J., Chang,J.G., Wu,S.C. and Choo,K.B.
  TITLE     Negative transcriptional modulation and silencing of the bi-exonic
            Rnf35 gene in the preimplantation embryo. Binding of the
            CCAAT-displacement protein/Cux to the untranslated exon 1 sequence
  JOURNAL   J Biol Chem 280 (35), 30681-30688 (2005)
   PUBMED   15994318
  REMARK    GeneRIF: Data show that the Rnf35 promoter is negatively modulated
            by the repressor element, DER, and that the 3'-half of DER (DER2)
            was targeted by the repressor CCAAT-displacement protein (CDP)/Cux.
REFERENCE   4  (bases 1 to 2156)
  AUTHORS   Huang,C.J., Wu,S.C. and Choo,K.B.
  TITLE     Transcriptional modulation of the pre-implantation embryo-specific
            Rnf35 gene by the Y-box protein NF-Y/CBF
  JOURNAL   Biochem J 387 (Pt 2), 367-375 (2005)
   PUBMED   15516209
REFERENCE   5  (bases 1 to 2156)
  AUTHORS   Choo,K.B., Chen,H.H., Liu,T.Y. and Chang,C.P.
  TITLE     Different modes of regulation of transcription and pre-mRNA
            processing of the structurally juxtaposed homologs, Rnf33 and
            Rnf35, in eggs and in pre-implantation embryos
  JOURNAL   Nucleic Acids Res 30 (22), 4836-4844 (2002)
   PUBMED   12433986
  REMARK    GeneRIF: Regulation of transcription and pre-mRNA processing of
            Rnf35 in eggs and in pre-implantation embryos.
REFERENCE   6  (bases 1 to 2156)
  AUTHORS   Chen,H.H., Liu,T.Y., Li,H. and Choo,K.B.
  TITLE     Use of a common promoter by two juxtaposed and intronless mouse
            early embryonic genes, Rnf33 and Rnf35: implications in zygotic
            gene expression
  JOURNAL   Genomics 80 (2), 140-143 (2002)
   PUBMED   12160726
  REMARK    GeneRIF: Rnf33 and Rnf35 mRNAs are apparently transcribed from the
            same putative promoter and may be products of alternative splicing.
REFERENCE   7  (bases 1 to 2156)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CF175045.1, AK054544.1 and BB709545.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Both variants 1 and 2 encode the same
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF175045.1, AK054544.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849382
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               CF175045.1         1-115
            116-2143            AK054544.1         2-2029
            2144-2156           BB709545.1         426-438
FEATURES             Location/Qualifiers
     source          1..2156
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 32.52 cM"
     gene            1..2156
                     /gene="Trim61"
                     /gene_synonym="2czf61; E330039K03Rik; Rnf35"
                     /note="tripartite motif-containing 61"
                     /db_xref="GeneID:260296"
                     /db_xref="MGI:MGI:2387432"
     exon            1..231
                     /gene="Trim61"
                     /gene_synonym="2czf61; E330039K03Rik; Rnf35"
                     /inference="alignment:Splign:2.1.0"
     exon            232..2156
                     /gene="Trim61"
                     /gene_synonym="2czf61; E330039K03Rik; Rnf35"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2126..2131
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim61"
                     /gene_synonym="2czf61; E330039K03Rik; Rnf35"
                     /note="hexamer: AATAAA"
     polyA_site      2145
                     /gene="Trim61"
                     /gene_synonym="2czf61; E330039K03Rik; Rnf35"
                     /note="major polyA site"
ORIGIN      
        1 ccagaagcaa ttcagtgatt ggccaattag ggaagccacc tgatgctctt caggaacaaa
       61 gcaagcagag aaagtaagag ggggtattgg gcatgcgcag ttccaagcct cgctcaattt
      121 cccaaggagc tgcccacaac tgagcaggca ggaccagcca cagcaggaat ggcccacgta
      181 ggcatggatg cagtgtctgg tgtaagctgc accacccgct ttctctaaca ggaaggactt
      241 agttccttgg atgtgaggca ccttacttct attgacttca ggtcactgag ctgggaaggc
      301 aacagccttg ttgaaatgtt ctgatataca gtcgtctgtg ggggctggac tctgccatct
      361 gactccggtg ctaaggcaca agggactaag caagttttca gagaccatca tcaacaaggc
      421 agtgaagcta aaagctggtc ggtcttccag agctaaggga ggaccagaga gtcaggcctt
      481 ctggaagcag tgtgtcctct cccacaacct ttgttcaggg ctcaatggag cttgctgcag
      541 ggctggccga tctccaagca gaggctcgct gttctgtctg taaggaatac ctcaagaacc
      601 cagggaccat ggagtgtggc cataaagtct gtctgtcctg caccagtgtg ttctgggagg
      661 atctaaaggg tagtgtcccc tgcccctctt gtcatttgaa ctgtccagga aggaactttt
      721 tgagtaatca gccaccaggt gagttcaccg aagttgccat cttgccccct gaaagaacta
      781 gcaggagtgg aaggcaagaa ggagagcatc catgggaaaa gccacaacag gtttcctgtc
      841 cactgcgcag cttccccccg aatcactttg tttggcccgt ggaaaatgct atcgtctgcc
      901 acaggaaaca aattgactgt tacattaagc tgtggaggga gatggtggag ccaatccaga
      961 aagcaattag cacacaaagg aaaggatcgc tagaactgag aaaaaggaca gaatgcagaa
     1021 gagaaagagt gaggtctcaa tatgaacaga ataggttgtt cctccaggtt gaacggaaga
     1081 agattcttgg gcacttacaa agtgaagaga tggatgggct atccaaacta aacaaaaacc
     1141 tagcgaaatt atcagatcac gcctccttgt taaagagtct gttgaaagat ctaaagagcc
     1201 agtgtgaaaa gtcagagctg gcattgctgg caagtgttaa agattggtac gagagataca
     1261 aacagtcggg atggcctgag atggccttag taacattgaa agggtacgac tacaggttac
     1321 ctctacagta ttctgactta gacagaatta tcaagcgatt tcaagttgat gtcattctgg
     1381 atcccgaaac agcaaactat aagcttacag tctcaaagga taaaaaaaca gttaaatatg
     1441 ggagttggga gagggtgccc tatagctcaa gaaaattttg ttttgaccct gctgttctgg
     1501 gatctgaggg atatagttct gacagacaat actgggaggt tgatgtggaa ctcaagatgg
     1561 aatgggttct aggggtctgt agggagcctt ttcccaggag caggtatgcc gaacggttct
     1621 ctgatgaaca gttctcagtg caggatggat tatggggagt tgggctagac aattcccaaa
     1681 cttatgttgc attgggtggt gagaaaatcc atcttcttcc caaagtatca cctactagga
     1741 ttgggatttt tttagattct gaaatgtatg aggtttcgtt ttacaatttg agggataaat
     1801 ccctgctgta caggtttagc gacttacctc ggggcacatt ttggccttac ttctacactg
     1861 gatatgacta cgagcctctg aagatttgca cagttgcaga tcttgagtga caacaagaca
     1921 gaacagccgg tggacagggc aggaggtggc tggcgtgggc agtggatagg ataatggggg
     1981 tttttgattt gctttttctt tgttttgctt tccttgtttt tcagttttca ctataacaat
     2041 cacaacagct attttgtttt taatctgcgt caggagtagc ctgtttgatg aaacaacgtc
     2101 caataatgac agacacatcc ttagaaataa aaattaaaac gttaagtttt tttgtt
//
