LOCUS       NM_145377               3493 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus tripartite motif-containing 41 (Trim41), mRNA.
ACCESSION   NM_145377 XM_978500 XM_978535 XM_982677 XM_982710 XM_982741
            XM_994167
VERSION     NM_145377.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3493)
  AUTHORS   Oura,S., Hino,T., Satoh,T., Noda,T., Koyano,T., Isotani,A.,
            Matsuyama,M., Akira,S., Ishiguro,K.I. and Ikawa,M.
  TITLE     Trim41 is required to regulate chromosome axis protein dynamics and
            meiosis in male mice
  JOURNAL   PLoS Genet 18 (6), e1010241 (2022)
   PUBMED   35648791
  REMARK    GeneRIF: Trim41 is required to regulate chromosome axis protein
            dynamics and meiosis in male mice.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3493)
  AUTHORS   Yu,Z., Li,X., Yang,M., Huang,J., Fang,Q., Jia,J., Li,Z., Gu,Y.,
            Chen,T. and Cao,X.
  TITLE     TRIM41 is required to innate antiviral response by
            polyubiquitinating BCL10 and recruiting NEMO
  JOURNAL   Signal Transduct Target Ther 6 (1), 90 (2021)
   PUBMED   33640899
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3493)
  AUTHORS   Chen,D., Gould,C., Garza,R., Gao,T., Hampton,R.Y. and Newton,A.C.
  TITLE     Amplitude control of protein kinase C by RINCK, a novel E3
            ubiquitin ligase
  JOURNAL   J Biol Chem 282 (46), 33776-33787 (2007)
   PUBMED   17893151
  REMARK    GeneRIF: RINCK is an E3 ligase that specifically recognizes the C1
            domain of PKC isoforms
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645849.17 and BC041780.1.
            
            On or before Feb 2, 2007 this sequence version replaced
            XM_994167.1, XM_982741.1, XM_982710.1, XM_982677.1, XM_978535.1,
            XM_978500.1, NM_145377.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC041780.1, SRR1660815.54217.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164132, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1549              AL645849.17        75566-77114         c
            1550-3493           BC041780.1         1512-3455
FEATURES             Location/Qualifiers
     source          1..3493
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 28.78 cM"
     gene            1..3493
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /note="tripartite motif-containing 41"
                     /db_xref="GeneID:211007"
                     /db_xref="MGI:MGI:2384814"
     exon            1..1549
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /inference="alignment:Splign:2.1.0"
     CDS             737..2629
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /EC_number="2.3.2.27"
                     /note="tripartite motif-containing protein 41; RING-type
                     E3 ubiquitin transferase TRIM41"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM41"
                     /protein_id="NP_663352.2"
                     /db_xref="CCDS:CCDS36138.1"
                     /db_xref="GeneID:211007"
                     /db_xref="MGI:MGI:2384814"
                     /translation="MAAVAMTPNPVQTLQEEAVCAICLDYFTDPVSIGCGHNFCRVCV
                     TQLWGGEDEEDRDELDREEEEEEVGEEEEVEAVGAGGGWDTPMREEDYEGDMEEEAEE
                     EEEVFWSSGIGGSNWDNMDYVWEEEEEEEEEELDYYLGDVADLRGEDEDEEEEVLEED
                     EEEELDPITQLPPPPAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRG
                     SRVNEQGICPRHQEALKLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQG
                     HVEPLRKHLEAVQKMKAKEERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLERR
                     LREMHEAQLGRAGAAANRLEEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEI
                     QLQPPEIWSPDPCQPHSHDFLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALLLSPDR
                     RGVRLAERRQEVPEHSKRFSADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTH
                     HKEKVGSGGSSVSSGDASSSRHHHRRRRLHLPQQLLLQREVWCVGTHGKRYQAQSSTE
                     QTLLSPCEKPRRFGVYLDYEAGRLGFYNADTLAHVHTFSAAFLGERVFPFFRVLSKGT
                     RIKLCP"
     exon            1550..1645
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1876
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1899
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /inference="alignment:Splign:2.1.0"
     exon            1900..2027
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /inference="alignment:Splign:2.1.0"
     exon            2028..3470
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3448..3453
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /note="hexamer: AATAAA"
     polyA_site      3470
                     /gene="Trim41"
                     /gene_synonym="RINCK"
                     /note="major polyA site"
ORIGIN      
        1 gagcgggccc gcccctcagc ttccggcact ggtcctggga gtcccttctg caatcgtccg
       61 tgcctggtcg gtaggatggc gctaggccgc tgcggttgga gcacggagaa cagggcgctg
      121 ctcaacgtcc tcgccaccct ccgctgtccg ttcccgctgg cagggcatgg gggcgccttc
      181 cgctccgtac gcgttcttcg cggccagtca tcaccgagac gtgggcctcc gccgtcctag
      241 ccctcccgtc ctgttcccga gtgtcagcta gagcgtctcc ttctcgtttc cggtcgctct
      301 gcagcctggg gcggggcgtg ggagaagggg gcggtgcctc gccgggaact cgtgagttca
      361 ggtagtgcgg agacgccgga agcgttggga gggaggccgg aagccggggg gcggggccag
      421 gaagtgagga ggggcggggg tttatgagca ggccagggga gcgttggggc agatttgcac
      481 tcaggtccac ctgagcggct tgtcggtggg gctcccctct gtcccctccc ctctgtgaga
      541 cacggtggtc gtctgggggt aggggactgt gcgtggcggg gtgggctggt cggaggacat
      601 tcctttggcc ttgccgcagg caaggtgcgg agaggttggg ctcggggtgg ggacggggct
      661 tcgggaaagg gagacccccc cgccccaccc cccgctcccc ccaccgcact tctaccctgg
      721 ctgactggac actaagatgg ctgccgttgc catgacaccc aaccctgtgc agacccttca
      781 ggaggaggcg gtgtgtgcca tctgcctcga ttacttcacg gacccggtgt ccatcggctg
      841 cgggcacaac ttctgccgag tgtgtgtaac ccagttgtgg ggcggggagg atgaggaaga
      901 cagagatgag ttggatcggg aggaggagga ggaggaggtc ggagaggagg aagaagtgga
      961 ggctgtcggg gctggcgggg gctgggacac ccctatgcgg gaagaagatt atgagggtga
     1021 catggaggag gaggccgagg aggaagagga agtgttctgg agtagtggta taggtgggtc
     1081 taactgggac aacatggact atgtgtggga ggaggaggag gaggaggagg aggaagaact
     1141 ggactattac ttgggggatg tggcggacct gagaggggaa gatgaggacg aggaggagga
     1201 agtgctggag gaagacgagg aagaggagct agacccgatc acccaactgc cgccacctcc
     1261 agcccctcgg agatgcttca cttgtcccca gtgtcgaaaa agttttcctc ggcggagctt
     1321 ccgccccaac ctgcagttgg ccaacatggt ccaggtgatc cgtcagatgc acccaactcc
     1381 tgggcgaggg agccgtgtga atgaacaagg catctgtccg agacatcaag aagccctgaa
     1441 gctgttctgt gaggtggatg aagaagccat ctgtgtggtg tgccgcgaat ccaggagcca
     1501 caaacagcat agtgtggtgc cattggagga ggtagtgcag gagtacaagg ccaagctaca
     1561 agggcatgtg gaaccactta ggaagcatct agaggctgtg cagaagatga aggccaagga
     1621 ggagaggcgg gtgacagagc tgaagagcca gatgaagtca gagctggcag ctgtggcctc
     1681 agagtttggg cggctaacaa ggtttctggc tgaagagcag gcaggattag agaggcgcct
     1741 ccgggagatg cacgaagctc agttaggacg tgcgggagca gcagccaacc gccttgaaga
     1801 gcaggctgcc cagctgagcc gcttgcttgc tgaagcccaa gaacggagcc aacagggggg
     1861 cctgcggcta ctgcaagaca tcaaggagac tttcaatagg tgtgaagaga tacagttgca
     1921 gcccccagag atttggtccc ctgacccatg ccaaccccat agccacgact tcctgacaga
     1981 cgccatcgtg aggaaaatga gccgcatgtt ttgtcaggct gcaagagtgg acctgacact
     2041 ggaccctgac acagctcacc cagctctgct gctgtcccct gatcgccgtg gagtccgctt
     2101 ggcagaacgt cggcaggagg ttcctgaaca ttccaagcgc ttctcagctg actgctgtgt
     2161 actaggggcc cagggcttcc gctctggccg gcactactgg gaggtagagg tgggtgggag
     2221 gcgaggctgg gcagtgggtg ctgcccgtga atcaacccat cataaagaaa aagtgggctc
     2281 tggggggtcc tctgttagca gtggggatgc cagctcctca cgccatcatc atcgccgccg
     2341 ccggctccat ctgcctcagc agctcctact ccagcgcgaa gtgtggtgtg tgggcaccca
     2401 cggcaaacga taccaggcac agagctcaac agagcagaca ctgctcagcc catgtgagaa
     2461 accacggcgc tttggcgtat acctggacta tgaggctggg cgcctaggct tctacaatgc
     2521 ggatacctta gcccatgtgc acaccttctc agctgccttc cttggcgagc gtgttttccc
     2581 ttttttccgg gtactttcca agggtacccg aatcaagctc tgcccttgat cagcctgcca
     2641 cccgcagggg cccctctggt caccactggg ggggcgggtg gtggtggatg gttgcccact
     2701 gttttgggag cctggattcc tcccactgtt tgttactgag ttgcttcctg ctccctcttg
     2761 aacccaggct gcttctccct ctaggagtca aaaagacctc ctagactcct ccagctcagt
     2821 ccttcctcac ctactttgtc tgacaggtct gcatgggtcc ctgataacca acagctgcct
     2881 gatgacctcc cctcccgcct agctcagctc tggggatgtg tggagataat tcctcaactt
     2941 tcctttttca cccccctcca tgttttggtg caagcttcag ctaagagctt taggagctgt
     3001 ctaggcaatc aggctgggca aaagggtaga gctgtgtaag tctacttttt cttggggaag
     3061 taggaacact aaagctttcc ttccaccccc caatttctac ctccatagac tggccagaat
     3121 ttagcttcag tgagatctga gatggtcagc atgacaccac atacattacc caataaatta
     3181 ttttctctct gcatcttatg taggagccta agtcttcttc tctgtcaggc tcttattcag
     3241 aagtttctgg cctctccatg ccttttattt ccacttggta agccctgtta gggagcttga
     3301 gacaggggtc tggatcctcg ggagaccact gggtataatc tatttttcta gtaacccctt
     3361 gccttctgac actaaacagc ttttgtcctc tgctttggtg gctgaggtca actcatgttc
     3421 ttggggaaag gtgggttgtg ttgcaaaaat aaaaaaaagt gtttatttgc aaaaaaaaaa
     3481 aaaaaaaaaa aaa
//
