LOCUS       NM_178281               3070 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus tripartite motif-containing 39 (Trim39), transcript
            variant 2, mRNA.
ACCESSION   NM_178281
VERSION     NM_178281.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3070)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3070)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   3  (bases 1 to 3070)
  AUTHORS   Orimo,A., Yamagishi,T., Tominaga,N., Yamauchi,Y., Hishinuma,T.,
            Okada,K., Suzuki,M., Sato,M., Nogi,Y., Suzuki,H., Inoue,S.,
            Yoshimura,K., Shimizu,Y. and Muramatsu,M.
  TITLE     Molecular cloning of testis-abundant finger Protein/Ring finger
            protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on
            the class I region of the human MHC
  JOURNAL   Biochem Biophys Res Commun 276 (1), 45-51 (2000)
   PUBMED   11006080
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY312131.1 and AK220298.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR,
            compared to variant 1. Variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK220298.1, SRR1660811.207267.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                BY312131.1         2-65
            65-3070             AK220298.1         1-3006
FEATURES             Location/Qualifiers
     source          1..3070
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.01 cM"
     gene            1..3070
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /note="tripartite motif-containing 39"
                     /db_xref="GeneID:79263"
                     /db_xref="MGI:MGI:1890659"
     exon            1..97
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /inference="alignment:Splign:2.1.0"
     exon            98..555
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..1569
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /EC_number="2.3.2.27"
                     /note="isoform 1 is encoded by transcript variant 2;
                     tripartite motif-containing protein 39; testis-abundant
                     finger protein; ring finger protein 23; RING-B
                     box-coiled-coil-B30.2; E3 ubiquitin-protein ligase TRIM39;
                     RING-type E3 ubiquitin transferase TRIM39"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM39 isoform 1"
                     /protein_id="NP_840065.1"
                     /db_xref="CCDS:CCDS37611.1"
                     /db_xref="GeneID:79263"
                     /db_xref="MGI:MGI:1890659"
                     /translation="MAETSLLEAGTSAASTAAALENLQVEASCSVCLEYLKEPVIIEC
                     GHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQTVKRKIR
                     DESLCSQHHEPLSLFCYEDQEAVCLICAISHTHRPHTVVPMDDATQEYKEKLQKCLEP
                     LEQKLQEITCCKASEEKKPGELKRLVESRRQQILKEFEELHRRLDEEQQTLLSRLEEE
                     EQDILQRLRENAAHLGDRRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTME
                     VTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVET
                     RLRDLPDTPQRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTP
                     LPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHI
                     YTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE"
     exon            556..651
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /inference="alignment:Splign:2.1.0"
     exon            652..882
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /inference="alignment:Splign:2.1.0"
     exon            883..905
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /inference="alignment:Splign:2.1.0"
     exon            906..1021
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..3070
                     /gene="Trim39"
                     /gene_synonym="1100001D15Rik; E130103K13Rik; mKIAA4179;
                     RBCC-B30.2; Rnf23; tfp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgtcgcgcc gcggggcggg ggtgagggga ggaggaagga gggaggcagt gctccggcgg
       61 ctccgcgccc ggcactccgg gacccggagc cgggaagtta taatggcaga gacaagtctg
      121 ttagaggctg gaacctctgc agcctccaca gccgctgctc tggagaacct gcaggtggaa
      181 gcaagctgtt ctgtatgcct agagtatctg aaggagccag ttattattga atgtgggcac
      241 aacttctgca aagcgtgcat tacccgctgg tgggaagacc tagagcggga cttcccttgc
      301 cctgtctgtc ggaagacatc ccgataccgg agtctccggc ctaaccgaca gctaggcagt
      361 atggtggaaa tcgccaagca gctccagacg gtcaagcgga agatcagaga tgaaagcctc
      421 tgctcccagc accacgaacc tcttagcctt ttctgctatg aagaccagga ggctgtctgt
      481 ctgatatgtg caatttctca tacccaccgg ccccacaccg tcgtgccgat ggatgatgct
      541 acacaggaat acaaggagaa acttcagaag tgcctggagc ccctggaaca gaagctgcag
      601 gagatcacct gctgcaaagc ctccgaagag aagaagccgg gggagctcaa gagactggtg
      661 gagagccgcc ggcagcagat cttaaaggag tttgaggagc tgcacaggcg actggacgaa
      721 gagcagcaga cactgctttc acgactggag gaagaagaac aggacattct acagcgactt
      781 cgagaaaatg ctgctcacct tggggacagg cgccgggacc ttgcccactt agctgctgag
      841 gtggagggca agtgcttaca gtcaggcttc gagatgctta aggatgtgaa aagtacccta
      901 gaaaaatgtg agaaggtgaa gaccatggag gtgacttcag tatccataga gctggaaaag
      961 aacttcagca atttcccccg gcagtacttt gccctaagga aaattcttaa acagctaatt
     1021 gcggatgtga ctctggaccc cgagactgct caccctaacc tcgtcctgtc agaggatcgg
     1081 aaaagcgtca agtttgtgga gacaagactc cgagacctcc ctgacacacc gcagcgtttc
     1141 actttctacc cttgtgtctt agctactgaa ggcttcacct caggtcgaca ctactgggag
     1201 gtggaggtgg gtgacaagac ccactgggca gtaggagtat gccgggactc tgtgagcaga
     1261 aagggcgaac tgactccact tcctgagact ggctactggc gagtgcggct gtggaatggg
     1321 gacaagtatg cagccaccac cacgcctttt acccctttgc acatcaaggt gaagcccaag
     1381 cgggtaggca tattcctaga ctatgaggct ggcacactgt ccttttacaa cgtcacagac
     1441 cgttcacata tctacacctt cactgatact tttactgaaa aactttggcc cctcttctac
     1501 ccagggatcc gggccggtcg gaagaatgct gcaccactta ccattaggcc cccaacagat
     1561 tgggaatgac aagagatgca gtttaattgg ggtgaggcaa ggtcaagagc ggtgggcctt
     1621 cctaactggc ctgctagaat atcttggtgt ctccgtggtt ccagtcttga gccatcttga
     1681 gaaaccacct cgcatctggg atggtttgtg tgaggagtaa agataggact gggctgcatg
     1741 accaagcaca gatgagtgtc cctccttact gtagtgggag agtggactcc caggggattg
     1801 tactctggtg tcccgcaggt ttcctagtgc acggggacag gttgagaaag caaaagcttt
     1861 ccagaaacaa agtctatagg aaagggtctt aacttgctta aaatgcagga aacagaaacc
     1921 tttaaaaggc ttctgtgacg cagaatagcc ttgttccttg tgggagcgca caggggtctg
     1981 tatacctcgg tgtcggaaag atgagtggca gttgctgtca tgagtctaga agtcgagggg
     2041 cttttccggg gccagagctt gagcattaaa gttaggagaa ggatcaggga agaggctgaa
     2101 ggaatgtttc taggatgaat gaagggaagg gggttttctt tggtctcttt tcttcttagg
     2161 gtaatgctat cattacccat aggattagcc agaggttcag atttggggag aaggaaagga
     2221 tggggaaaaa ggagactcca tgtcccaaag gcttgcgtta ttcctgtttc ctgcagttgg
     2281 ctgtctctaa aaagtaggct cctcttgctt ccttctaaag gtgagatgga agcaatcctg
     2341 caagacatac atctgagccg ggcgtggtgg catacccggg aggcagagac aggcggattt
     2401 ctgagttcaa ggccagcctg gtctacaaag tgagttccag gacagccaca gctatacaga
     2461 gaaaccctgt ctcaaaaaac tcaaaaagaa aaagacatac atcggtcctt ccattgtttc
     2521 ccaaggcaac ttggagagga gtcagatatt agaggagaga gaaaggtgta gctaaagcct
     2581 tggccttaag gaatgttcct aagtggttat tcccaacttg tccaccttgc cccctggctc
     2641 aaagacctaa ggaaagaagg gaaggtgatg gagtctttct cacccatgag aacagggtag
     2701 aagagggtgg tttgtgtagc aaagggccag aagacagcta agcttctatt tctatccttc
     2761 accctttgac attccccttt tcagagaatg taaattattt taattttagg ccaaaataaa
     2821 caacccatag ggtacatatt ttgtcacaaa aggtaccaga tgcatgccaa accaaacaac
     2881 ctggattatc tgctgcctgg gtaatcttca cacaagactg agacaagaaa ctgcagtgag
     2941 ggcattcagt tcctcctacc acctcaacag gactttgtcc actctactct tacctttgtg
     3001 ccttgactgt ggttctttgt ggcaagataa ttggttggtg aaaatatgga acaaaggatc
     3061 cactaatgtg
//
