LOCUS       NM_001170855            4555 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus tripartite motif-containing 36 (Trim36), transcript
            variant 2, mRNA.
ACCESSION   NM_001170855
VERSION     NM_001170855.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4555)
  AUTHORS   Suzuki,A., Yabuta,N., Shimada,K., Mashiko,D., Tokuhiro,K.,
            Oyama,Y., Miyata,H., Garcia,T.X., Matzuk,M.M. and Ikawa,M.
  TITLE     Individual disruption of 12 testis-enriched genes via the
            CRISPR/Cas9 system does not affect the fertility of male mice
  JOURNAL   J Reprod Immunol 163, 104252 (2024)
   PUBMED   38697008
REFERENCE   2  (bases 1 to 4555)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4555)
  AUTHORS   Aoki,Y., Tsujimura,A., Kaseda,K., Okabe,M., Tokuhiro,K., Ohta,T.,
            O'Bryan,M.K., Okuda,H., Kitamura,K., Ogawa,Y., Fujiki,T., Wada,M.,
            Horie,S., Nishimune,Y. and Tanaka,H.
  TITLE     Haprin-deficient spermatozoa are incapable of in vitro
            fertilization
  JOURNAL   Mol Reprod Dev 87 (5), 534-541 (2020)
   PUBMED   32311190
  REMARK    GeneRIF: Haprin-deficient spermatozoa are incapable of in vitro
            fertilization.
REFERENCE   4  (bases 1 to 4555)
  AUTHORS   Zhang,Y., Yokoyama,S., Herriges,J.C., Zhang,Z., Young,R.E.,
            Verheyden,J.M. and Sun,X.
  TITLE     E3 ubiquitin ligase RFWD2 controls lung branching through
            protein-level regulation of ETV transcription factors
  JOURNAL   Proc Natl Acad Sci U S A 113 (27), 7557-7562 (2016)
   PUBMED   27335464
REFERENCE   5  (bases 1 to 4555)
  AUTHORS   van Beuningen,S.F.B., Will,L., Harterink,M., Chazeau,A., van
            Battum,E.Y., Frias,C.P., Franker,M.A.M., Katrukha,E.A., Stucchi,R.,
            Vocking,K., Antunes,A.T., Slenders,L., Doulkeridou,S., Sillevis
            Smitt,P., Altelaar,A.F.M., Post,J.A., Akhmanova,A.,
            Pasterkamp,R.J., Kapitein,L.C., de Graaff,E. and Hoogenraad,C.C.
  TITLE     TRIM46 Controls Neuronal Polarity and Axon Specification by Driving
            the Formation of Parallel Microtubule Arrays
  JOURNAL   Neuron 88 (6), 1208-1226 (2015)
   PUBMED   26671463
REFERENCE   6  (bases 1 to 4555)
  AUTHORS   Nakano,Y., Jahan,I., Bonde,G., Sun,X., Hildebrand,M.S.,
            Engelhardt,J.F., Smith,R.J., Cornell,R.A., Fritzsch,B. and Banfi,B.
  TITLE     A mutation in the Srrm4 gene causes alternative splicing defects
            and deafness in the Bronx waltzer mouse
  JOURNAL   PLoS Genet 8 (10), e1002966 (2012)
   PUBMED   23055939
REFERENCE   7  (bases 1 to 4555)
  AUTHORS   Quina,L.A., Wang,S., Ng,L. and Turner,E.E.
  TITLE     Brn3a and Nurr1 mediate a gene regulatory pathway for habenula
            development
  JOURNAL   J Neurosci 29 (45), 14309-14322 (2009)
   PUBMED   19906978
REFERENCE   8  (bases 1 to 4555)
  AUTHORS   Miyajima,N., Maruyama,S., Nonomura,K. and Hatakeyama,S.
  TITLE     TRIM36 interacts with the kinetochore protein CENP-H and delays
            cell cycle progression
  JOURNAL   Biochem Biophys Res Commun 381 (3), 383-387 (2009)
   PUBMED   19232519
REFERENCE   9  (bases 1 to 4555)
  AUTHORS   Short,K.M. and Cox,T.C.
  TITLE     Subclassification of the RBCC/TRIM superfamily reveals a novel
            motif necessary for microtubule binding
  JOURNAL   J Biol Chem 281 (13), 8970-8980 (2006)
   PUBMED   16434393
REFERENCE   10 (bases 1 to 4555)
  AUTHORS   Kitamura,K., Tanaka,H. and Nishimune,Y.
  TITLE     Haprin, a novel haploid germ cell-specific RING finger protein
            involved in the acrosome reaction
  JOURNAL   J Biol Chem 278 (45), 44417-44423 (2003)
   PUBMED   12917430
  REMARK    GeneRIF: results indicated that the novel RBCC protein Haprin plays
            a key role in the acrosome reaction and fertilization
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC124717.3, CJ046908.1, BC058106.1, CJ301781.1 and BM938922.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR, lacks a
            portion of the 5' coding region, and initiates translation at an
            alternate start codon, compared to variant 1. The encoded isoform
            (2) has a distinct N-terminus and is shorter than isoform 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223969.18570.1,
                                           SRR7345562.138317.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 AC124717.3         107998-107999
            3-305               CJ046908.1         2-304
            306-2938            BC058106.1         225-2857
            2939-4000           BC058106.1         2859-3920
            4001-4414           CJ301781.1         31-444
            4415-4555           BM938922.1         294-434
FEATURES             Location/Qualifiers
     source          1..4555
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 24.41 cM"
     gene            1..4555
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /note="tripartite motif-containing 36"
                     /db_xref="GeneID:28105"
                     /db_xref="MGI:MGI:106264"
     exon            1..305
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            306..540
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            541..866
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1013
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1109
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1363
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1488
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            1489..1779
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            1780..2077
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     exon            2078..4545
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2472..2477
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /note="hexamer: AACAAA"
     polyA_site      2530
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /note="major polyA site"
     regulatory      4386..4391
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /note="hexamer: AATAAA"
     regulatory      4393..4398
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /note="hexamer: AATAAA"
     polyA_site      4406
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
     polyA_site      4411
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
     regulatory      4524..4529
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
                     /note="hexamer: ATTAAA"
     polyA_site      4545
                     /gene="Trim36"
                     /gene_synonym="D18Wsu100e; haprin"
ORIGIN      
        1 gcagtccgcg cgagccgccg ccgcagccgg cagccgggcg tcattcgcgg ctcccggggc
       61 ccttgcaggg agcaaccgca ctctcccgcg cccgtggttt cgcctgcgcc ggccagttcc
      121 tcgccgcgtg gcccgctggc cggatctggc tgaccagctt gctctccggt ctgacccgag
      181 gctcccgagc cgcctcgggg actcgcccac acgaccctgc tagggccggc tgcgcctgta
      241 aagactccgt ggttaatgtc acccggcgga gggctgcgat ggagggggat gcctcagact
      301 ctcaggtgac tattaagaat atcgaaaagg agcttatttg cccagcgtgc aaggagctgt
      361 ttacccaccc gctgatcctt ccctgccagc acagcgtctg tcataagtgt gtgaaagaac
      421 ttttactgtc tcttgatgac tcgttcaatg atgtggcgtc agacagctca aatcagagca
      481 gccctaggct ccggctcacc tcccctagca tggataaaat cgacaagatt aacagaccag
      541 gctggaagcg taattcactg accccgagac caaccacgtt cccttgtcct ggctgtgaac
      601 atgatgtgga tcttggagag cgaggagtca gtggtctgtt tcgaaatttc actttggaaa
      661 cgattgtcga gagataccgg caggccgcta gggcagccac agccattatg tgtgaccttt
      721 gtaaacctcc accccaggaa tctacaaaga gctgcatgga ttgtagtgca agctactgca
      781 atgaatgctt caaaatttat catccctggg gcactgtaaa agcccagcat gagtatgtgg
      841 gccccaccac taatttcaga cccaaggttc taatgtgccc agaacatgag acagagagaa
      901 taaacatgta ctgtgaacta tgcagaaggc cagtttgcca cctctgtaag ttgggtggga
      961 atcattccaa tcaccgggta accaccatga gcagtgccta caaaacctta aaggagaaac
     1021 tttcaaaaga cattgatttc cttattggca aggaaagcca ggtgaagagt caaatttctg
     1081 aactaaactt gctaatgaaa gagacagagt gcaacggaga gagggcgaag gaagaagcgc
     1141 tggcgcattt tgaaaagctc tttgaaatcc tggaagacag gaagtcgtct gttctgaaag
     1201 ccatagatgc ctctaagaaa ctaagactag acaagtttca cactcagatg gaagagtacc
     1261 aaggccttct agagaataac gggctcgtgg ggtatgctca ggaagtgctg aaggagacgg
     1321 atcagtcttg ctttgtgcag acggcgaagc agctccatct cagaatacag aaagctacgg
     1381 agtccctgaa gagctttaga cctgcagccc aggcttcttt tgaagactat gttgttaaca
     1441 tatcgaaaca aacagaggtg cttggagagt tgtccttttt ctccagtggc atagacattc
     1501 ctgagatcaa cgaggaacag agtaaagtgt ataataacgc cttgatagac tggcatcatc
     1561 cagaaaagga caaagccgac agctatgttc tagaataccg caagattaat agagacgaag
     1621 aaatgatatc atggaatgag atagaagttc acggcacaag taaagttgtc tccaaccttg
     1681 aaagcaacag tccctatgcg ttccgagtga gagcttacag gggttctatc tgcagtccct
     1741 gcagcagaga attgatcctg catactcctc cagctccagt tttcagtttc ctgttcgatg
     1801 agaagtgtgg ctacaacact gagcacctct tgctgaacct gaagagagac cgggtggaga
     1861 gcagagctgg atttaacgtc ctcctggctg cggagcgcat ccaagtgggc cattacacaa
     1921 gcttagacta catcatcggg gatgtcggag tcacgaaagg taaacacttc tgggcctgcc
     1981 gcgtggaacc gtattcatac ctggtgaaag tgggagttgc ttccagcgac aaactgcaag
     2041 agtggctgcg ctctccccga gatgcagcta gtccaagata tgagcaagac agtggacatg
     2101 acagtggaag cgaggacgcc tgttttgatt cttcacagcc ctttacatta gttactatag
     2161 gcatgaagaa attttttata cccaagtcac ctacttcctc taatgaacca gaaaacagag
     2221 ttctccccat gccaacgagt atagggattt tccttgactg tgataaaggc aaagtgagct
     2281 tctatgatat ggaccacatg aaatgcctgt atgagcgcca ggtggactgt tcgcatacaa
     2341 tgtatccggc ctttgccttg atgggcagcg gaggaattca gcttgaggaa gccatcacag
     2401 caaagtatct ggaatatgaa gaggatgtgt agcttggaca ccccacgtga ctgatgagga
     2461 taagaaccgt gaacaaagcc atgccttgat gttaatctaa ttacatatca tttacgtctc
     2521 tgtcaccaca cctgtttgta ctgtgtgatt ctttgttttg tcttgtcctg ctgtgacaca
     2581 cagggtcttg ctgtgtagtc caggcgggcc tcaaactctg ttctgttata gcctctggag
     2641 ggctaggatt ataggtgggc accaccatcc ccagctagtg tatggttctt aaaactcaga
     2701 aggacttcac aaccttgtct cttccacgtc attgtcctac ctattacaaa tggtgggagt
     2761 ggaggctttc tgtcttaact ggtctagaat agataacttt acaatggaag tccttctctt
     2821 tggccacagg gactctaatt gatgtaagtc taattggtta ttcatgtccc tttgtttggg
     2881 ggctggggtg ggatacaaag tatttattgt ggttctttga gcttgttttt ttttttttcc
     2941 ttttcatttt gtatcatgtt catgtccaaa gagaagatat ttttgaatgc ttactgatag
     3001 aaactagtac taagccatgt gtcttgcatt tgatgttaat agaaaaataa atttatagat
     3061 aggtaaaatg acaaaggcca taaaatggta gtatatttaa gtagaaagtt gtgtatttta
     3121 aagtgtgtaa ctactgagaa tattcatcgc ctggcaaatg aatactgctt ttttccctgt
     3181 agaccacaga ctgtattagt aaggacatct ctaacagtgt ccttgttgta atgcccattg
     3241 tctggcacat gtaacaagca tcgtttcata taaaaacaca gggttcttga acccgtgcaa
     3301 cttttcacta caatataatt atttccagga aatgttatct tcaaattttc ttactttaga
     3361 aaatattcat atttatagca aagaattatt tttcagaatt actagggaag atggactgat
     3421 agtgaacacg tgtctctttg tgtcttgtga attttatggg tttggtactt atgttgtaca
     3481 tcagggtttt atggtttttg tttacaaatc tgagaagttc actgcccatt ttcagcagca
     3541 ttgaaatacc agacatgtta catgttacta ctgtccagtt ggatggcatt atttgtgggc
     3601 tcattgtgtg gtcataagca cttgtagtgt gaatcagtaa agtacaaaat tcctaggaaa
     3661 taatatggaa aatcacaagg atgtgtctag tcagttttta tatcttttct acattgaatg
     3721 ttaatttctg caaaattacc ttctgattat ttgaattgcc tttttaaaag ttaaaatgtc
     3781 cagacactaa gacatgtttt cagcactgat catgtatgga atgttaacat tttagtagaa
     3841 taaccaaagc tgtttatttt atttattttt tcgaggcagg gtttctctgt gtagtcctgg
     3901 ctgtcctgga actcactctg tagaccaggc tggccttgaa ctcagaaatc tgcctgcctc
     3961 tgcctcccaa gtgctgggat taaaggtgtg tgccaccact gcccggctct atttgattat
     4021 ttttaatgga agcctgttag gccaatcaca ctgcgtctga cgcagcactg actgacacac
     4081 acacacaccc ctaagctcgt gtagaaaggt gtggaggatt tgtgtttagt gattgtcctt
     4141 cctctcccat ttatatgtag cactttatga cataggaaac agagagaatg tgcagtgtta
     4201 cctgggtcat tgtgcaataa agctgctagt gtcacccgtg tgtgggttag tgtgatactc
     4261 aatactcatg tgagcacatg tcctgtagac gttttaaaat ataaagcttt aacaggagtc
     4321 agagaaggaa gctgttcaaa cactgtatca ctctatagaa attgcttagt ggaatttcaa
     4381 tttttaataa aaaataaata aataaaggga agccaagtgt agttattcaa gtctgcacta
     4441 cagggatttt ttactctgct ttgtggaaaa ccgaaacaga acacttacta taagatgctt
     4501 tgtggcacat gttaattttt ttaattaaaa aagatttatt cttaaaaaaa aaaaa
//
