LOCUS       NM_199146               3770 bp    mRNA    linear   ROD 26-JUN-2024
DEFINITION  Mus musculus tripartite motif-containing 30D (Trim30d), transcript
            variant 1, mRNA.
ACCESSION   NM_199146 XM_133684
VERSION     NM_199146.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3770)
  AUTHORS   Schafer,A., Marzi,A., Furuyama,W., Catanzaro,N.J., Nguyen,C.,
            Haddock,E., Feldmann,F., Meade-White,K., Thomas,T., Hubbard,M.L.,
            Gully,K.L., Leist,S.R., Hock,P., Bell,T.A., De la Cruz,G.E.,
            Midkiff,B.R., Martinez,D.R., Shaw,G.D., Miller,D.R., Vernon,M.J.,
            Graham,R.L., Cowley,D.O., Montgomery,S.A., Schughart,K., de
            Villena,F.P.M., Wilkerson,G.K., Ferris,M.T., Feldmann,H. and
            Baric,R.S.
  TITLE     Mapping of susceptibility loci for Ebola virus pathogenesis in mice
  JOURNAL   Cell Rep 43 (5), 114127 (2024)
   PUBMED   38652660
REFERENCE   2  (bases 1 to 3770)
  AUTHORS   Taylor,R.T., Lubick,K.J., Robertson,S.J., Broughton,J.P.,
            Bloom,M.E., Bresnahan,W.A. and Best,S.M.
  TITLE     TRIM79alpha, an interferon-stimulated gene product, restricts
            tick-borne encephalitis virus replication by degrading the viral
            RNA polymerase
  JOURNAL   Cell Host Microbe 10 (3), 185-196 (2011)
   PUBMED   21925107
  REMARK    GeneRIF: TRIM79 restricts tick-borne encephalitis virus replication
            by degradation the NS5 protein, an RNA-dependent RNA polymerase
            essential for virus replication.
REFERENCE   3  (bases 1 to 3770)
  AUTHORS   Tareen,S.U., Sawyer,S.L., Malik,H.S. and Emerman,M.
  TITLE     An expanded clade of rodent Trim5 genes
  JOURNAL   Virology 385 (2), 473-483 (2009)
   PUBMED   19147168
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK136456.1, AC122400.4 and BX525206.1.
            
            On Nov 17, 2009 this sequence version replaced NM_199146.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC056631.1, SRR1660819.156969.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164135 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-179               AK136456.1         5-183
            180-655             AC122400.4         50776-51251
            656-3752            AK136456.1         184-3280
            3753-3770           BX525206.1         374-391
FEATURES             Location/Qualifiers
     source          1..3770
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 55.69 cM"
     gene            1..3770
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /note="tripartite motif-containing 30D"
                     /db_xref="GeneID:209387"
                     /db_xref="MGI:MGI:3035181"
     exon            1..179
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /inference="alignment:Splign:2.1.0"
     exon            180..655
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /inference="alignment:Splign:2.1.0"
     CDS             236..1729
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /note="isoform 1 is encoded by transcript variant 1;
                     tripartite motif-containing 79"
                     /codon_start=1
                     /product="tripartite motif-containing 79 isoform 1"
                     /protein_id="NP_954597.2"
                     /db_xref="CCDS:CCDS40069.1"
                     /db_xref="GeneID:209387"
                     /db_xref="MGI:MGI:3035181"
                     /translation="MASSVLEMIKEEVTCPICLELLKESVSADCNHSFCRACITLHYE
                     SNRNPEGEGNCPVCRVPYLFENLRPNRHVANIVERLKGFKSIPEEEQKVNACVEHGEK
                     LQLFCKEDMMAICWLCKQSQEHSGHQTALIEEVNHEYKEKLQAALQKLMENEKRCDEW
                     QDDLQQQRADWENQIHSDIEDIQIEFNGLRDLLDSKENEKLQELKKEKEEVMEKLEES
                     EHELREQRELVRDLISYVQHQLELSVMEMKQGVNYVLTSIQTMTLKQPQIVPPKRRRG
                     TSKAPHLKGMLQSFEGLMDVQQYWVHMTLHARNNAVIAINKEKRQIQYRSYNTVPVSE
                     IYHLGVLGYPALSSGKHYWEVDISRSDAWLLGLNDGKCAQPQLHSKEEMGIKKKYHSH
                     IKQNVTFQPKCGYWVIGMKNSSVYNAFDECSITHNSSVLALSLPDRPSRVGVFLDQEV
                     CTLSFYDVSNSGALIYRFYDPSFPVEVYPYFNPMECSEPMTVCGPPS"
     exon            656..751
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /inference="alignment:Splign:2.1.0"
     exon            752..982
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1005
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1109
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1136
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..3758
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3734..3739
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /note="hexamer: AATAAA"
     polyA_site      3758
                     /gene="Trim30d"
                     /gene_synonym="TRIM30-3; Trim79"
                     /note="major polyA site"
ORIGIN      
        1 tttctctact ggctcttcag aggagcagca cagttggctg aatcatcagg acttagactc
       61 tggcctgtat ttgttcctct ccacaaatcc tgggtctctt ggttggtatc tgaaggtgtg
      121 agccaatttt caactgcaga gtttgaagaa atttagaaga aggcacagtc tttgctctgc
      181 catccatgca taagtgtgag aagtcaggac aggcagacac aggatcacag caactatggc
      241 ctcatcagtc ctggagatga taaaggaaga agtgacctgc ccaatctgtc tggagctctt
      301 gaaggaatct gtgagtgctg actgtaacca cagcttctgc agagcctgca tcacactgca
      361 ctatgagtct aacagaaacc cagaagggga gggcaactgc cctgtgtgcc gagttcctta
      421 cctgtttgag aatctgaggc ctaatcgaca tgttgccaac atagtagaga ggctcaaggg
      481 attcaagtcc atcccagagg aggagcagaa ggttaatgcc tgtgtagaac atggagagaa
      541 actccagctc ttctgtaagg aggacatgat ggccatctgc tggctttgta agcaatccca
      601 ggagcacagt ggtcaccaaa cagctctcat tgaagaggtc aaccatgaat acaaggagaa
      661 gctacaggca gctctgcaga agctgatgga aaatgagaaa agatgtgatg aatggcagga
      721 tgaccttcag caacagagag ctgactggga gaaccaaata cacagtgata tagaagacat
      781 tcagatagag tttaatggac taagagacct cctagactcc aaggagaatg agaagctgca
      841 ggagctgaag aaagagaagg aagaggttat ggaaaagctg gaagagtctg aacatgagct
      901 aagggagcag agggagttgg tgagagacct catctcatat gttcagcatc agttggagct
      961 gtcagtcatg gaaatgaagc agggtgtaaa ttatgtcctg acaagcattc agaccatgac
     1021 actgaagcag ccccaaatag ttcccccaaa aagaagaaga ggaacatcca aagctccaca
     1081 tttgaaaggc atgctacagt catttgaagg gctcatggat gttcagcaat actgggttca
     1141 tatgactcta catgcaagga acaatgcagt cattgccatt aacaaagaaa aaagacaaat
     1201 acagtataga agttacaata cggttccagt ttctgagatc taccatttgg gtgtcctggg
     1261 atatccagct ctttcctcag ggaagcatta ctgggaagta gacatatcta gaagtgatgc
     1321 ctggctcctc ggattaaatg acggaaagtg tgctcaaccc caacttcact caaaggaaga
     1381 aatgggcatc aaaaaaaaat atcattctca tattaaacaa aatgtaacgt ttcagcctaa
     1441 atgtggctac tgggttatag ggatgaagaa ttcatctgta tacaatgcct ttgatgagtg
     1501 ttctatcacc cacaattcca gtgtcttggc cctctctctg cctgatcgtc ccagtcgtgt
     1561 aggagttttc ctggaccagg aagtttgcac tctctcattt tatgatgttt ctaactctgg
     1621 agctctcatc tatagattct atgacccttc cttccctgtt gaagtctatc catattttaa
     1681 tcctatggaa tgttcagagc caatgacagt atgcggacca ccatcctaaa ccctcaccta
     1741 tacctgtgca gtgcccccat gtctccgctg catcattcta acttttttgt cttgggccct
     1801 ttattgtaat gaccttcact tctaatccca aaccactgtg gattcatttc cttgatccag
     1861 tagcttgtct gctcacaaga tgattactgt catttgtcat ttccaatatt tccccccccc
     1921 caaaaaaata gctgttccct cactaagtga aatagagccc ctgataatgc catctctgta
     1981 ggaacgcagt caaaagaatg actcacagtg aacaatgtct tagttacctg tgagagaggc
     2041 cccagaaaaa aagaagaaaa aaaagggcag agagccttca acctcaagga catttttgtt
     2101 ccctggattg ctttggatgt gaatttgggc ctcctgcaaa aagaacatct gcattcaatt
     2161 tttaagatac atttactctt gttcaatatc agaatatagc tatagaaccc attcctgtgc
     2221 aaggctatac tgagtgccag cctcagtgta cactggttct gaatatgggc ttatgccttg
     2281 attttgtgat ttccaagata tattttatag tatagtgcca gacaattgtg cttatatagt
     2341 ctgccctgat aaagttgtag gaaagttttc ctctgtgaat atttatgaat agtatgttct
     2401 tactggtatc tatttacatg ttttactgat tatgtttttc taaactcaaa aaaccttcag
     2461 gagtactctt gtatattcat atataaaagc acattttgaa actgaagtaa tgttgtctat
     2521 aggattaggc tgtagtcccc tgcttctttg agaccaattc tgcaaacacc aggtcgtaca
     2581 gacagaacta cctaggtcca caacggtaaa caactttcct tcttgtggtg acagagatag
     2641 aagccagggc ttcgtgagtg cttatgagtt gctctaccac tgagttactt gcctcagttc
     2701 tgtcaggtct ctatagccac attctttctg tcactgacaa aagatgagag aaaattcttc
     2761 tccaacgtgt ctaacagttt aggaaattat atgtaggtgt ctctctttaa agaatgggcc
     2821 ttagcagaag gtcagtttaa ccacaatact tgtgtttcat gaaagagtta agaaggaaag
     2881 atctcaaatg atatctacta tgaccatgtg tttagagtac ccaggttcta atcctgcctc
     2941 tccacatagc agtgcaacct tgaataacat tttttcaagc ttatgtttgc ttgggttttt
     3001 tcttttggtt catttttctt gtttgttttt cagttttggt ataaatagta cctctatatt
     3061 gcaggtcatt gtaggaaaat aaatttgaaa tctttagaag gctctgggag taaaagccct
     3121 ttcctctatg agtgatgaac tgagttaact tactcagacc atcttggctg aaggaggcag
     3181 ccagctctga gagatgatcc tctcactgca caaatatact acagaacaac taggctaaaa
     3241 cacacacaca aatgagaaag gattgtggaa tttttagcaa aagaagttca atacttacaa
     3301 tgcatccagt acacattcag taggtggtaa ttgtgctaat tactgtgtaa atgtgctgta
     3361 cttatgttct atgtgacact ttgtaactgg agaaactaag atatagctct tctcatgtct
     3421 tgatgttagg ttctgtgaac tgccaccaag actactctaa tatcttgtag atatgtatga
     3481 tttttttttg ttttcacact tattttttaa gaaggtattt gtttagctgt atttgttatc
     3541 aagtaagcta aagtctatga ttttctattt tataatgaat gataatgatg acaatgatac
     3601 ccataaccat acctgctgtt gtgttgtaaa atgtaaacaa tagaatgttt ctaggaactc
     3661 ctattgcttc tagcatataa gggatgtcca tatggtatct gtaaagtttt tttctccctt
     3721 ttaataggac cataataaag tatcattgga atgacaaaaa aaaaaaaaaa
//
