LOCUS       NM_001357467            3809 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus tripartite motif-containing 30A (Trim30a), transcript
            variant 2, mRNA.
ACCESSION   NM_001357467 XM_006507471
VERSION     NM_001357467.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3809)
  AUTHORS   Schafer,A., Marzi,A., Furuyama,W., Catanzaro,N.J., Nguyen,C.,
            Haddock,E., Feldmann,F., Meade-White,K., Thomas,T., Hubbard,M.L.,
            Gully,K.L., Leist,S.R., Hock,P., Bell,T.A., De la Cruz,G.E.,
            Midkiff,B.R., Martinez,D.R., Shaw,G.D., Miller,D.R., Vernon,M.J.,
            Graham,R.L., Cowley,D.O., Montgomery,S.A., Schughart,K., de
            Villena,F.P.M., Wilkerson,G.K., Ferris,M.T., Feldmann,H. and
            Baric,R.S.
  TITLE     Mapping of susceptibility loci for Ebola virus pathogenesis in mice
  JOURNAL   Cell Rep 43 (5), 114127 (2024)
   PUBMED   38652660
REFERENCE   2  (bases 1 to 3809)
  AUTHORS   Afolabi,L.O., Bi,J., Chen,L., Yang,X. and Wan,X.
  TITLE     Suppression of protein quality control system by TRIM30a sensitises
            tumour cells to NK cell-mediated immune surveillance
  JOURNAL   Immunology 171 (1), 60-76 (2024)
   PUBMED   37753964
  REMARK    GeneRIF: Suppression of protein quality control system by TRIM30a
            sensitises tumour cells to NK cell-mediated immune surveillance.
REFERENCE   3  (bases 1 to 3809)
  AUTHORS   Liu,H., Zhou,R., Li,S., Dong,J., Fang,Y., Luo,Y., Su,H., Lai,B.,
            Liang,L., Zhang,D., Zhang,Y., Shyy,J.Y., Zhou,B., Yuan,Z. and
            Wang,Y.
  TITLE     Epigenetic repression of Cend1 by lysine-specific demethylase 1 is
            essential for murine heart development
  JOURNAL   iScience 27 (1), 108722 (2023)
   PUBMED   38226173
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3809)
  AUTHORS   Lee,M., Liu,Y.C., Chen,C., Lu,C.H., Lu,S.T., Huang,T.N., Hsu,M.T.,
            Hsueh,Y.P. and Cheng,P.L.
  TITLE     Ecm29-mediated proteasomal distribution modulates excitatory GABA
            responses in the developing brain
  JOURNAL   J Cell Biol 219 (2) (2020)
   PUBMED   31910261
REFERENCE   5  (bases 1 to 3809)
  AUTHORS   Da Silva,F., Massa,F., Motamedi,F.J., Vidal,V., Rocha,A.S.,
            Gregoire,E.P., Cai,C.L., Wagner,K.D. and Schedl,A.
  TITLE     Myocardial-specific R-spondin3 drives proliferation of the coronary
            stems primarily through the Leucine Rich Repeat G Protein coupled
            receptor LGR4
  JOURNAL   Dev Biol 441 (1), 42-51 (2018)
   PUBMED   29859889
REFERENCE   6  (bases 1 to 3809)
  AUTHORS   Tareen,S.U., Sawyer,S.L., Malik,H.S. and Emerman,M.
  TITLE     An expanded clade of rodent Trim5 genes
  JOURNAL   Virology 385 (2), 473-483 (2009)
   PUBMED   19147168
REFERENCE   7  (bases 1 to 3809)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   8  (bases 1 to 3809)
  AUTHORS   Reymond,A., Meroni,G., Fantozzi,A., Merla,G., Cairo,S., Luzi,L.,
            Riganelli,D., Zanaria,E., Messali,S., Cainarca,S., Guffanti,A.,
            Minucci,S., Pelicci,P.G. and Ballabio,A.
  TITLE     The tripartite motif family identifies cell compartments
  JOURNAL   EMBO J 20 (9), 2140-2151 (2001)
   PUBMED   11331580
REFERENCE   9  (bases 1 to 3809)
  AUTHORS   Ben-Zur,T. and Wides,R.
  TITLE     Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse
            chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human
            chromosome Xq25
  JOURNAL   Genomics 58 (1), 102-103 (1999)
   PUBMED   10331952
REFERENCE   10 (bases 1 to 3809)
  AUTHORS   Patarca,R., Freeman,G.J., Schwartz,J., Singh,R.P., Kong,Q.T.,
            Murphy,E., Anderson,Y., Sheng,F.Y., Singh,P., Johnson,K.A. et al.
  TITLE     rpt-1, an intracellular protein from helper/inducer T cells that
            regulates gene expression of interleukin 2 receptor and human
            immunodeficiency virus type 1
  JOURNAL   Proc Natl Acad Sci U S A 85 (8), 2733-2737 (1988)
   PUBMED   2965815
  REMARK    Erratum:[Proc Natl Acad Sci U S A 1988 Jul;85(14):5224]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122400.4 and AC142110.4.
            
            On Oct 28, 2017 this sequence version replaced XM_006507471.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253013.3011282.1,
                                           SRR17253012.1820967.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-222               AC122400.4         92702-92923
            223-686             AC122400.4         102782-103245
            687-782             AC122400.4         108601-108696
            783-1013            AC122400.4         109476-109706
            1014-1036           AC142110.4         170441-170463       c
            1037-1137           AC142110.4         161221-161321       c
            1138-1164           AC142110.4         160925-160951       c
            1165-3809           AC142110.4         158031-160675       c
FEATURES             Location/Qualifiers
     source          1..3809
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 55.69 cM"
     gene            1..3809
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /note="tripartite motif-containing 30A"
                     /db_xref="GeneID:20128"
                     /db_xref="MGI:MGI:98178"
     exon            1..222
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /inference="alignment:Splign:2.1.0"
     exon            223..686
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /inference="alignment:Splign:2.1.0"
     CDS             267..1757
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /note="regulatory protein, T lymphocyte 1; tripartite
                     motif protein 30; tripartite motif-containing protein 30;
                     down regulatory protein of interleukin-2 receptor;
                     tripartite motif-containing 30"
                     /codon_start=1
                     /product="tripartite motif-containing protein 30A"
                     /protein_id="NP_001344396.1"
                     /db_xref="CCDS:CCDS40068.1"
                     /db_xref="GeneID:20128"
                     /db_xref="MGI:MGI:98178"
                     /translation="MASSVLEMIKEEVTCPICLELLKEPVSADCNHSFCRACITLNYE
                     SNRNTDGKGNCPVCRVPYPFGNLRPNLHVANIVERLKGFKSIPEEEQKVNICAQHGEK
                     LRLFCRKDMMVICWLCERSQEHRGHQTALIEEVDQEYKEKLQGALWKLMKKAKICDEW
                     QDDLQLQRVDWENQIQINVENVQRQFKGLRDLLDSKENEELQKLKKEKKEVMEKLEES
                     ENELEDQTELVRDLISDVEHHLELSTLEMLQGANCVLRRSQSLSLQQPQTVPQKRKRT
                     FQAPDLKGMLQVYQGLMDIQQYWVHMTLHARNNAVIAINKEKRQIQYRSYNTVPVSEI
                     YHLGVLGYPALSSGKHYWEVDISRSDAWLLGLNDGKCAQPQLHSKEEMGIKKNLHSQI
                     KQNVLFQPKCGYWVIGMKNPSVYKAFDECSITHNSSILVISLPDRPSRVGVFLDRKAG
                     TLSFYDVSNCGALIYRFYDPAFPVEVYPYFNPMKCSEPMTICGPPS"
     exon            687..782
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /inference="alignment:Splign:2.1.0"
     exon            783..1013
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1036
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1137
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1164
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..3809
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3785..3790
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /note="hexamer: AATAAA"
     polyA_site      3809
                     /gene="Trim30a"
                     /gene_synonym="Rpt-1; Rpt1; Trim30"
                     /note="major polyA site"
ORIGIN      
        1 agtttctttt tctcagttcc tgccctcaca gtcttaactt tcatttctct actggctccc
       61 aagaggacca gcacagttgg ctgaatcctc aggacttaga ctcttgcctg tgtttgctcc
      121 tctccacaaa tcctgggtct cttggttggt atctgaaggt gtgagccaat tttcaactgc
      181 agagtttgga ggaatttaga agaagacaca gtctttgctc tgcagtgtga ggagtcagga
      241 caggcagaca caggatcaca gcaactatgg cctcatcagt cctggagatg ataaaggagg
      301 aagtaacctg tcctatctgt ttggagctcc tgaaggaacc tgtgagtgct gattgtaacc
      361 acagcttctg cagagcctgc atcacactga attatgagtc caacagaaac acagacggga
      421 agggcaactg ccctgtatgc cgagttcctt acccatttgg gaatctgagg cctaatctac
      481 atgtggccaa catagtagag aggctcaagg gattcaagtc cattccagag gaggagcaga
      541 aggtgaatat ctgtgcacaa catggagaga aactccggct cttctgtagg aaggacatga
      601 tggtcatctg ctggctttgt gagcgatctc aggagcaccg tggtcaccaa acagctctca
      661 ttgaagaggt tgaccaagaa tacaaggaga agctgcaggg agctctgtgg aagctgatga
      721 aaaaggcaaa aatatgtgat gaatggcagg atgaccttca actgcagaga gttgactggg
      781 agaaccaaat acagatcaat gtagaaaatg ttcagagaca gtttaaagga ctaagagacc
      841 tcctggactc caaggagaat gaggagctgc agaagctgaa gaaagagaag aaagaggtta
      901 tggaaaagct ggaagagtct gaaaatgagc tggaggatca gacagagttg gtgagagacc
      961 tcatctcaga tgtggaacat catttggagc tctcaacctt agaaatgctg cagggtgcaa
     1021 attgtgtcct gagaaggagt cagtccttaa gcctgcaaca gccccaaact gtcccccaaa
     1081 agagaaaaag aacattccaa gctccagatc tgaaaggcat gctgcaagtg tatcaaggac
     1141 tcatggatat ccagcaatac tgggttcata tgactctaca tgcaaggaac aatgcagtca
     1201 ttgccattaa caaagaaaaa agacaaatac agtatagaag ttacaatacg gttccagttt
     1261 ctgagatcta ccatttgggt gtcctgggat atccagctct ttcctcaggg aagcattact
     1321 gggaagtaga catatctaga agtgatgcct ggctcctcgg attaaatgac ggaaagtgtg
     1381 ctcaacccca acttcactca aaggaagaaa tgggcatcaa aaaaaacctt cattctcaga
     1441 tcaaacaaaa tgtattgttt cagcctaaat gtggctactg ggttataggg atgaagaatc
     1501 cgtctgtata caaggccttt gatgagtgtt ctatcaccca caattccagt atcctggtca
     1561 tctctctgcc tgatcgtccc agtcgtgtcg gagttttcct ggatcggaaa gctggcactc
     1621 tctcatttta tgatgtttct aactgcggtg ctctcatcta taggttctat gaccctgcct
     1681 tccctgttga agtctatcca tattttaatc ctatgaaatg ttcagagcca atgactatat
     1741 gcgggccacc ctcctaaacc ttcacctata tctatatcta tatctatcta tatctatatc
     1801 tatatctata tctatatcat ctatatcttt atacagtgcc cccatgtctg gtgtatctta
     1861 tgcaagaaac cccttgcatc attctaactt cttttttgtc ttgggccttt tattttaatg
     1921 accttcactt ctaaccccaa accactgtag attcatttcc ttgatccagt tgcttgtctg
     1981 ttcacaagat gattactgtc atgtatcatt tcccatattc aaaaaaaaaa aaaatagttg
     2041 tttcctcaca aagtaaaata gatcctctgc taacaccatc tctgtagaaa cacagtcaaa
     2101 agaatgactc atggtgaaca atgtcttagg gacctgtaag agaagcccca gagaaaaaga
     2161 aagagggcct ttaacctcag ggacattttg ttccctggat tgctttggat gtgattttgt
     2221 gcctcctgca aaaagaacat ctgcattcaa tttgtaagat ctgtttactc ttgttggatg
     2281 tcagaacata gctatagatc caattcctgt gcaaggatat actgaatgct ggcctcaatg
     2341 tacaaattct gaatatggac ttgtgccttg atctcatttt tttcaagata tcatctatag
     2401 catagtacca gacacttgtg tttatatggt ctgtcctgag acagttgtag gaaaggtttg
     2461 ttaatatgtt cttactggta tgtatttcca tgtttttctg atttggttct tctgaactca
     2521 tcaaccttcc tgctttcttt tgtacattca tgtttaaaag cacagtgaaa ctgaaataaa
     2581 gttgtctgca gcatcaggct gtagtccccc cattctttaa ggtctgcaaa ccccagatct
     2641 tacagacaga actacatagg cccacaacgg tatgcacacc ttctttttgg tgttgccaga
     2701 gatagaagcc agggattcgt gagtgcttat gagttgctct acccctgagt tacttgcctc
     2761 agctctgtca ggtctccaca gctgcattct ttctgaaact gaaaaagctg agagaaagtt
     2821 cttctccagt gtgtctagca gtttaggaaa ttatatgtag gagtctgtct ttaaggaatg
     2881 ggacttagca gaaggtcagt ttaaccacaa tgcttgtgtt tcatcaaaaa gttaagaagg
     2941 agacatctca aatgatatcc actaagacca tgtgtttaga atacccaggt tctaatcctg
     3001 tctctccaca tagcattaca accctgaata acatcatctc aagcctgttt gtttgttctt
     3061 ttctttgttt gtttcatttt tcttttttgt ttttcagttt tgctaaaata gcacacctat
     3121 attacacgtc attttaggaa aataaatttg aaatctttac aaggctctga gagtaaaagc
     3181 cctttcctct gtgagtgatg aactgtgttc atttacttag accctcttgg ctgaaggaag
     3241 cagccagctc tgagagatga tcatcttact tcacaaatat gctacagaac atctaggctg
     3301 aaactcatac aaatgagagg agactatgtt atttttagta agaaaagatc aataggtata
     3361 atgtgtccag tgcacactct gtaagtgggg attgtgctaa ttactgggta gatgtgctgt
     3421 actgatgttc tatgtggcac tgaggaaact aaggtataga tcttctcatg tctggatatt
     3481 agatcctgga agctgccgcc aagaatattc taatgtgttg tggatatata tgattttttt
     3541 tcttttcaca cttacttttt gaaaggatat ttgtttagct gtattcatta tcaagtaagt
     3601 taaaatctat gattttccat tcacaataaa taataataat gacaatgata cccataactg
     3661 aaccttctgt tatgttgtga aatgtaaaca atagaatgtt tctaggaact catattgctt
     3721 ctagcagata gaaggtatca gatactgtat ctgttaagtt ttttctaccc tttgttgtga
     3781 ccacaataaa gtaccattgg aatgacaaa
//
