LOCUS       NM_023835               1553 bp    mRNA    linear   ROD 06-OCT-2024
DEFINITION  Mus musculus tripartite motif-containing 12A (Trim12a), transcript
            variant 2, mRNA.
ACCESSION   NM_023835 XM_001002841 XM_001005484
VERSION     NM_023835.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1553)
  AUTHORS   Schafer,A., Marzi,A., Furuyama,W., Catanzaro,N.J., Nguyen,C.,
            Haddock,E., Feldmann,F., Meade-White,K., Thomas,T., Hubbard,M.L.,
            Gully,K.L., Leist,S.R., Hock,P., Bell,T.A., De la Cruz,G.E.,
            Midkiff,B.R., Martinez,D.R., Shaw,G.D., Miller,D.R., Vernon,M.J.,
            Graham,R.L., Cowley,D.O., Montgomery,S.A., Schughart,K., de
            Villena,F.P.M., Wilkerson,G.K., Ferris,M.T., Feldmann,H. and
            Baric,R.S.
  TITLE     Mapping of susceptibility loci for Ebola virus pathogenesis in mice
  JOURNAL   Cell Rep 43 (5), 114127 (2024)
   PUBMED   38652660
REFERENCE   2  (bases 1 to 1553)
  AUTHORS   Orozco,L.D., Cokus,S.J., Ghazalpour,A., Ingram-Drake,L., Wang,S.,
            van Nas,A., Che,N., Araujo,J.A., Pellegrini,M. and Lusis,A.J.
  TITLE     Copy number variation influences gene expression and metabolic
            traits in mice
  JOURNAL   Hum Mol Genet 18 (21), 4118-4129 (2009)
   PUBMED   19648292
REFERENCE   3  (bases 1 to 1553)
  AUTHORS   Boon,A.C., deBeauchamp,J., Hollmann,A., Luke,J., Kotb,M., Rowe,S.,
            Finkelstein,D., Neale,G., Lu,L., Williams,R.W. and Webby,R.J.
  TITLE     Host genetic variation affects resistance to infection with a
            highly pathogenic H5N1 influenza A virus in mice
  JOURNAL   J Virol 83 (20), 10417-10426 (2009)
   PUBMED   19706712
REFERENCE   4  (bases 1 to 1553)
  AUTHORS   Tareen,S.U., Sawyer,S.L., Malik,H.S. and Emerman,M.
  TITLE     An expanded clade of rodent Trim5 genes
  JOURNAL   Virology 385 (2), 473-483 (2009)
   PUBMED   19147168
REFERENCE   5  (bases 1 to 1553)
  AUTHORS   Blackburn,A.C., Hill,L.Z., Roberts,A.L., Wang,J., Aud,D., Jung,J.,
            Nikolcheva,T., Allard,J., Peltz,G., Otis,C.N., Cao,Q.J.,
            Ricketts,R.S., Naber,S.P., Mollenhauer,J., Poustka,A., Malamud,D.
            and Jerry,D.J.
  TITLE     Genetic mapping in mice identifies DMBT1 as a candidate modifier of
            mammary tumors and breast cancer risk
  JOURNAL   Am J Pathol 170 (6), 2030-2041 (2007)
   PUBMED   17525270
REFERENCE   6  (bases 1 to 1553)
  AUTHORS   Norman,B., Davis,J. and Piatigorsky,J.
  TITLE     Postnatal gene expression in the normal mouse cornea by SAGE
  JOURNAL   Invest Ophthalmol Vis Sci 45 (2), 429-440 (2004)
   PUBMED   14744882
REFERENCE   7  (bases 1 to 1553)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
REFERENCE   8  (bases 1 to 1553)
  AUTHORS   Reymond,A., Meroni,G., Fantozzi,A., Merla,G., Cairo,S., Luzi,L.,
            Riganelli,D., Zanaria,E., Messali,S., Cainarca,S., Guffanti,A.,
            Minucci,S., Pelicci,P.G. and Ballabio,A.
  TITLE     The tripartite motif family identifies cell compartments
  JOURNAL   EMBO J 20 (9), 2140-2151 (2001)
   PUBMED   11331580
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC142110.4, AK009769.1 and DV553257.1.
            
            On Sep 22, 2006 this sequence version replaced NM_023835.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK009769.1, SRR13422592.17508.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-39                AC142110.4         64463-64501         c
            40-1523             AK009769.1         2-1485
            1524-1553           DV553257.1         234-263
FEATURES             Location/Qualifiers
     source          1..1553
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 55.69 cM"
     gene            1..1553
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /note="tripartite motif-containing 12A"
                     /db_xref="GeneID:76681"
                     /db_xref="MGI:MGI:1923931"
     exon            1..85
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /inference="alignment:Splign:2.1.0"
     exon            86..561
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /inference="alignment:Splign:2.1.0"
     CDS             142..1035
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /note="isoform 2 is encoded by transcript variant 2;
                     tripartite motif protein 12; tripartite motif-containing
                     protein 12; tripartite motif-containing 12; tripartite
                     motif-containing protein 12A"
                     /codon_start=1
                     /product="tripartite motif-containing protein 12A isoform
                     2"
                     /protein_id="NP_076324.2"
                     /db_xref="CCDS:CCDS40067.1"
                     /db_xref="GeneID:76681"
                     /db_xref="MGI:MGI:1923931"
                     /translation="MASQFMKNLKEEVTCPVCLNLMVKPVSADCGHTFCQGCITLYFE
                     SIKCDKKVFICPVCRISYQFSNLRPNRNVANIVERLKMFKPSPEEEQKVFNCARHGKK
                     LQLFCRKDMMAICWLCERSQEHRGHKTALIEEVAQEYKEQLQVVLQRLMADKKKFENW
                     KDDLQKDRTYWENQIQKDVQNVRSEFKRMRDIMDSEEKKELQKLRQEKEDILNNLAES
                     ESEHAQQSKLLEDFISDVEHQLQCSDIEILQGVENIIERSHTFSMKKPKAIAREQRKF
                     RAPDLQGMLQVLQEVTEAHRY"
     exon            562..657
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /inference="alignment:Splign:2.1.0"
     exon            658..888
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /inference="alignment:Splign:2.1.0"
     exon            889..911
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1009
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1036
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1525
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1504..1509
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /note="hexamer: AATAAA"
     regulatory      1509..1514
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /note="hexamer: AACAAA"
     polyA_site      1522
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /note="major polyA site"
     polyA_site      1525
                     /gene="Trim12a"
                     /gene_synonym="2310043C01Rik; Trim12"
                     /note="major polyA site"
ORIGIN      
        1 agagttgtgg tttctgtttc atttccagag ctcaaacttt cctttctcta gattttagcc
       61 ggaaatacct tgaagttctg gattggcacc tgagcagaag tgcgaggagt caggacagtc
      121 atacacagga tcacagcaac tatggcttca caattcatga agaatttaaa ggaggaggtg
      181 acctgtcctg tctgtctgaa cctgatggtg aaacctgtga gtgcagattg tggtcacacc
      241 ttctgccaag gctgcatcac gttgtacttt gaatccatca aatgcgataa gaaagtgttc
      301 atttgccctg tgtgccgaat tagttaccag tttagcaatc tgaggcctaa tcgaaatgtg
      361 gccaacatag tagagaggct caaaatgttc aagcccagcc cagaagagga gcagaaagtg
      421 tttaactgtg caagacatgg aaagaaactc cagctcttct gtaggaagga catgatggcc
      481 atctgctggc tttgtgagcg atctcaggag caccgtggtc acaaaacagc tctcattgaa
      541 gaggtggccc aggagtacaa ggagcagctg caggtagttc tgcaaaggct gatggcagat
      601 aagaaaaaat ttgaaaactg gaaagatgac cttcagaagg atagaactta ctgggagaat
      661 caaatacaga aagatgtgca gaatgttcgg tcagagttta aacgaatgag ggatatcatg
      721 gactctgagg agaagaagga attgcagaag ctgaggcaag agaaggaaga cattctcaac
      781 aacctggcag agtctgaaag tgagcatgct cagcagagca agttgctaga agacttcatc
      841 tcagatgtgg aacatcagtt acagtgctca gacatagaaa tactgcaggg tgtggagaac
      901 atcatagaac ggagtcatac tttttcgatg aagaagccca aagccatcgc cagggaacaa
      961 agaaagttcc gagcccctga cctgcaaggc atgctgcaag tgctgcaaga ggtcacagag
     1021 gctcatcgct actaggggtc ttcctccctc cgccatggac aaattttcgc acacatcttt
     1081 ggaccctcac ctctggccag gaaggggaga tctttcatcc aggcagaagt ggtgaagaaa
     1141 agccagggac tggttttaac cagccaaacc aaccagcagc ccctcccttt ctgttctggc
     1201 tgggggtgtg ggggagaaac tgaaactcca aaccagcaga tacaggaaag aggaggaaac
     1261 ttttgagtcc taagtactgg caaaactcta ggccaccaat agatggcaat gcagggactc
     1321 tggtcatcca aggctagagg agaagttttc agcggccagg aagagctttt tggtggccat
     1381 agctaagggc tgtcacttac atcaggtggg taaagaccat gttaagggaa gattccactc
     1441 agcaagaagg cagccacaaa ctcaaaagaa acacgagaaa cttttattaa tgtgtgaccc
     1501 gaaaataaaa caaatggccc agcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//
