LOCUS       NM_011280               2249 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Mus musculus tripartite motif-containing 10 (Trim10), transcript
            variant 2, mRNA.
ACCESSION   NM_011280
VERSION     NM_011280.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2249)
  AUTHORS   Kong,L., Sui,C., Chen,T., Zhang,L., Zhao,W., Zheng,Y., Liu,B.,
            Cheng,X. and Gao,C.
  TITLE     The ubiquitin E3 ligase TRIM10 promotes STING aggregation and
            activation in the Golgi apparatus
  JOURNAL   Cell Rep 42 (4), 112306 (2023)
   PUBMED   36972172
  REMARK    GeneRIF: The ubiquitin E3 ligase TRIM10 promotes STING aggregation
            and activation in the Golgi apparatus.
REFERENCE   2  (bases 1 to 2249)
  AUTHORS   Yang,H., Wang,X.X., Zhou,C.Y., Xiao,X., Tian,C., Li,H.H., Yin,C.L.
            and Wang,H.X.
  TITLE     Tripartite motif 10 regulates cardiac hypertrophy by targeting the
            PTEN/AKT pathway
  JOURNAL   J Cell Mol Med 24 (11), 6233-6241 (2020)
   PUBMED   32343488
  REMARK    GeneRIF: Tripartite motif 10 regulates cardiac hypertrophy by
            targeting the PTEN/AKT pathway.
            Erratum:[J Cell Mol Med. 2023 Jul;27(13):1915-1917. doi:
            10.1111/jcmm.17773. PMID: 37394903]
REFERENCE   3  (bases 1 to 2249)
  AUTHORS   Blaybel,R., Theoleyre,O., Douablin,A. and Baklouti,F.
  TITLE     Downregulation of the Spi-1/PU.1 oncogene induces the expression of
            TRIM10/HERF1, a key factor required for terminal erythroid cell
            differentiation and survival
  JOURNAL   Cell Res 18 (8), 834-845 (2008)
   PUBMED   18560381
  REMARK    GeneRIF: Primary Spi-1/PU.1 downregulation acts on late erythroid
            differentiation through at least two pathways, one of which
            requires TRIM10/HERF1 upregulation and parallels the
            Spi-1/PU.1-induced Fli-1 shutoff regulatory cascade.
REFERENCE   4  (bases 1 to 2249)
  AUTHORS   Uchil,P.D., Quinlan,B.D., Chan,W.T., Luna,J.M. and Mothes,W.
  TITLE     TRIM E3 ligases interfere with early and late stages of the
            retroviral life cycle
  JOURNAL   PLoS Pathog 4 (2), e16 (2008)
   PUBMED   18248090
REFERENCE   5  (bases 1 to 2249)
  AUTHORS   Takada,T., Kumanovics,A., Amadou,C., Yoshino,M., Jones,E.P.,
            Athanasiou,M., Evans,G.A. and Fischer Lindahl,K.
  TITLE     Species-specific class I gene expansions formed the telomeric 1 mb
            of the mouse major histocompatibility complex
  JOURNAL   Genome Res 13 (4), 589-600 (2003)
   PUBMED   12671000
REFERENCE   6  (bases 1 to 2249)
  AUTHORS   Reymond,A., Meroni,G., Fantozzi,A., Merla,G., Cairo,S., Luzi,L.,
            Riganelli,D., Zanaria,E., Messali,S., Cainarca,S., Guffanti,A.,
            Minucci,S., Pelicci,P.G. and Ballabio,A.
  TITLE     The tripartite motif family identifies cell compartments
  JOURNAL   EMBO J 20 (9), 2140-2151 (2001)
   PUBMED   11331580
REFERENCE   7  (bases 1 to 2249)
  AUTHORS   Harada,H., Harada,Y., O'Brien,D.P., Rice,D.S., Naeve,C.W. and
            Downing,J.R.
  TITLE     HERF1, a novel hematopoiesis-specific RING finger protein, is
            required for terminal differentiation of erythroid cells
  JOURNAL   Mol Cell Biol 19 (5), 3808-3815 (1999)
   PUBMED   10207104
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY712181.1, AK011082.1 and AI324236.1.
            
            On Aug 4, 2009 this sequence version replaced NM_011280.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK011082.1, BC051632.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849388, SAMN00849390
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2                 BY712181.1         2-3
            3-2237              AK011082.1         3-2237
            2238-2249           AI324236.1         1-12                c
FEATURES             Location/Qualifiers
     source          1..2249
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.16 cM"
     gene            1..2249
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /note="tripartite motif-containing 10"
                     /db_xref="GeneID:19824"
                     /db_xref="MGI:MGI:1338757"
     exon            1..734
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            735..830
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            831..1061
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1084
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1200
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            1201..1233
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            1234..2245
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2217..2222
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /note="hexamer: GATAAA"
     regulatory      2221..2226
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /note="hexamer: AATAAA"
     polyA_site      2236
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
                     /note="major polyA site"
     polyA_site      2245
                     /gene="Trim10"
                     /gene_synonym="Herf1; Rnf9"
ORIGIN      
        1 gagagactgt gagcagcttc gggtggacag aaagttgcag tgagctccag gccatgggaa
       61 ctggtccaga gagttaactt atggtgcttt gagcccctgg gccttcctcc tctatttctt
      121 cacctatgct gttggcagga gtgtgtctgc tcctgggaga gcaggacaag gggctctggt
      181 gccagagatg taactgggtc ccttgtccca gtgtgggtga ctatgttggt gttcaggcct
      241 gatgtgggtg tggagggtga gcagagacgg tgacttccag cgtcagaagg cctggtagga
      301 ttgacatggc ctcagctcct tctgtgacta gcctggcaga tgaggtcaac tgccccatct
      361 gccaaggcac cctgagggag ccagtcacca ttgactgtgg ccacaacttc tgtcgtggct
      421 gcctcactcg ctactgcgag atcccaggtc cagaatcaga ggagtccctc agctgcccgc
      481 tctgcaaaga gcccttccgc ccagggagct tccggcccaa ctggcagctg gccaatgtgg
      541 tggagaacat cgagcgcctt cagctggcgt ccacgcgagg cctggaggtg gaggatgcct
      601 gtccggaaca cggggagaaa atctacttct tttgcgagga ggatgaggca cagttgtgtg
      661 tggtatgccg cgaaaccgga cagcatgggg ctcacactgt gcgcttcctg gaggacgcag
      721 caggtcccta cagggaacaa atacagaagt gtctcgtgtg tctaaggaaa gagagagaag
      781 agattcaaga aacccagtca agagaaaaca aaagaataca ggtgctcctg actcaggtgg
      841 ccaccaagag gcaacaggtg atctcacagt ttgcgcatct gagccagttc ctgcagcaac
      901 agcagactgc cctcttagca caactggagg ggttagacgg ggacatcttg aagcagcagg
      961 aagagtttga ttccctggcc actggggaga tctgccggtt cagcaccctg attgaggagc
     1021 tggaggagaa gaacaagagg acagccaggg ggctcctgac ggatatcaga agcactctaa
     1081 taagatgtga aaccagaaag tgccggaaac ccgaggctat atccccagag ctgggccaaa
     1141 ggatccggga cttcccccaa caggccatcc ctctgcggca ggagatgaag acatttctgg
     1201 aaaaactctg ttttgagttg gactatgagc cagctcatat ctctctagac ccccagactt
     1261 cccaccccaa gctcctcctc tctgaagacc accgacgggc tcggttctcc tacaaatggc
     1321 agaattcacc agatactcca caacgctttg atcgagtcac ctgtgttctg gcccaatgtg
     1381 gttttacagg ggggagacac acttggatgg tgaatgttga cttggcccat ggaggcagct
     1441 gcactgtagg tgtggtcaga gaagatgtac gacggaaggg agaattgagg ctgagaccag
     1501 aggagggaat atgggcagtg aggctggctt ggggctttgt ttcagctctg ggttctttcc
     1561 ccacaaggct ggccctggag gagcaacccc ggaaggtgca ggtatctctt gactatgagg
     1621 taggctggat aaccttcgtc aatgctgtca ctcaggagca tatctatacc ttcactgcct
     1681 cctttacaca gaagatcttt cccttgtttg gactctgggg cagagggtcc agtttttccc
     1741 tgagctgtca ggaaggtgca gtttccctcc tctgagtatg agactggaat caagcaccct
     1801 tgggagcaga ccctcggctg ggtcaccaag cacaaagtga attttttaga cattgtttgg
     1861 catgtgtcag taagggacaa agtggtagga cctttagttt cttcattgtt caagcctttc
     1921 cccagtgccc atcagatact cgggtatctg ggaccttggc tgcgctggct gttctcacca
     1981 ttggcatcaa tgggcacaga catagatgta caaacagtgc tggattttaa gcctcgagac
     2041 ctggattcca ggtgaagccc tgtaatcaac cagctgtgtg atttcaaaca aaactttgcc
     2101 tcttcatttt gttttcttcc aaagatatta gctagttttt ttcatatctt caagaaacac
     2161 tttggagaag tggatatgat caaagtacac tatatacatt aattaaattc cagaaggata
     2221 aataaaaata ttatttgaaa aggaaaaaa
//
