LOCUS       NM_146241               6655 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus TRH-degrading enzyme (Trhde), mRNA.
ACCESSION   NM_146241
VERSION     NM_146241.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6655)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   2  (bases 1 to 6655)
  AUTHORS   Yaylaoglu,M.B., Titmus,A., Visel,A., Alvarez-Bolado,G., Thaller,C.
            and Eichele,G.
  TITLE     Comprehensive expression atlas of fibroblast growth factors and
            their receptors generated by a novel robotic in situ hybridization
            platform
  JOURNAL   Dev Dyn 234 (2), 371-386 (2005)
   PUBMED   16123981
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC160408.6, BC032288.1 and AC124558.4.
            
            On Jul 26, 2019 this sequence version replaced NM_146241.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            CCDS Note: The coding region has been updated to start at an
            upstream start codon that is supported by conservation data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC032288.1, AK034093.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-938               AC160408.6         17737-18674
            939-6452            BC032288.1         12-5525
            6453-6655           AC124558.4         101011-101213
FEATURES             Location/Qualifiers
     source          1..6655
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 61.59 cM"
     gene            1..6655
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /note="TRH-degrading enzyme"
                     /db_xref="GeneID:237553"
                     /db_xref="MGI:MGI:2384311"
     exon            1..1784
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..2058
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2059..2185
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2186..2340
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2341..2454
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2455..2592
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2593..2658
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2659..2724
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2725..2912
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            2913..3001
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3002..3135
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3136..3191
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3192..3339
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3340..3437
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3438..3545
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3546..3713
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3714..3854
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3855..3936
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            3937..6655
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4277..4282
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /note="hexamer: AAGAAA"
     polyA_site      4295
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /note="major polyA site"
     regulatory      5010..5015
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /note="hexamer: AATACA"
     polyA_site      5027
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /note="major polyA site"
     regulatory      6632..6637
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
                     /note="hexamer: AATATA"
     polyA_site      6655
                     /gene="Trhde"
                     /gene_synonym="9330155P21Rik"
ORIGIN      
        1 agttcttccc ccggggacgc ggctcagacc ttcatctacc tgaagtggac accccgaccg
       61 gacacttctt cacttgtctt ctctggaggg cagagcatca tcggaacgcg ggaggcttgc
      121 tgcccagtcc gcaacctcac gccttttacc gccaccactg cttaaagtgt ccagggtgga
      181 gaaggcttct tcaggacgga tgctccgcgg ccgtgggact tcctccggct agcttactcc
      241 agtcctttcc tcggtcctct ggtccatcct ctcctcttcc actgcggggt ggaaggctcc
      301 agcgccttcc gggctgccgc cgctgccacc gccgcaactg ttttggcgag cacatcccac
      361 ccagaagacg gaacaacgct gccagagtgc ggggggctgg tgaagcccta acttgtcccc
      421 cgactcagtc gctctcccca gcgctctctg tcctcttggc cgagccgagg agagagcaac
      481 cgccgccgcc accctggtag agtgcggcgc ccgggaggac aggcgagccg caggcgcaca
      541 ggggcggggg cggcgtgtgc ccgggcgccc ggtgctggcc cgacgagtag cgcgcacccg
      601 gcgagcgaca cgcttcccaa gttggggcgc gtcccagagc tggttgcccg gctatccgca
      661 gctgttgtct ggagagaggc ggggctgatg ggggtcgtct cggtcgtcac tagcctccag
      721 agtctgtctt gagagaatct gagctggcct ccctagggtc ccagccggcg tcgcgccctc
      781 cgcccgcgtg cggtctccaa tgactgcgct ggaggtggcc cgggtggccc gcccgctagg
      841 ggtgtcggag ggggcggggg aagaggagga ggcggtgtga tggccctgga cggcgagagg
      901 ggggagcaag aggaggagaa gaaaaagaag aagaagaaaa agaagaggaa gaagaaggag
      961 gaggaggggg cagagaagag cagttcaccc tttgcggcca ccatgggaga agacgacgcc
     1021 gcgctccggg caagcggcag ggggctctcg gacccgtggg ctgactcggt gggagtgaga
     1081 ccccgcacca cggagcgcca catcgcagtg cacaagaggc ttgtgctggc ctttgccgtg
     1141 tccatcgtgg cactgctggc tgtcaccatg ctggccgtcc tgctcagctt gcgattcgac
     1201 gagtgtggag cgagcgcggc gatgcctggc accgacggtg gcctcggggg tttccccgag
     1261 cgcgacagca acagcagctt tccaggttct gcccggcgca accaccacgc gggtggggaa
     1321 tcctctcagc gtgagagcgg cgaggtgggc accccgggga ccccgtctgc ccagccgccg
     1381 tcggaggaag agcgggagca gtggcagccc tggacacagc tgcgcctatc cggccacctc
     1441 aagccgctgc actacaattt gatgctcacc gctttcatgg agaacttcac cttctctggg
     1501 gaggtcaacg tggagatcgc gtgccggaac gccacccgct acgtggtact gcacgcctcc
     1561 cgagtggcgg tggagaaggt gcaagtagct gaagacaggg cgttcggggc tgtcccggtt
     1621 gcaggctttt tcctctaccc acaaacgcag gtcttggtgg tggtattgaa cagaaccctg
     1681 gacgcgcaga ggcattacaa tctgaagatt atctacaatg ccctgataga gaacgagctt
     1741 ttgggcttct tccgcagctc ctacgtgatc cacggggaga gaagattcct tggtgttact
     1801 cagttttcac ctacacatgc caggaaggcg tttccgtgtt tcgatgaacc aatctacaag
     1861 gccactttca aaatcagcat caaacatcaa gcaacctatt tgtctctatc caacatgcca
     1921 gtggaaacgt ctgtgttcga ggaagatgga tgggtgacag atcacttttc acagacccct
     1981 ctcatgtcta catattattt agcctgggcg atttgcaact tcacatacag agaaactacc
     2041 accaagagtg gggttgtagt ccgattatat gcgagacccg acgctatcag aagaggatcc
     2101 ggggactatg ctctccacat tacaaagaga ttaatagaat tttatgaaga ctactttaaa
     2161 gtgccctatt ctttgccaaa actagatctt ttagctgtgc ctaagcatcc ttatgctgct
     2221 atggagaact ggggactaag tatttttgtg gaacaaagaa tactgctgga tcccagtgtg
     2281 tcatctattt cttatttgct ggatgtcacc atggtcattg ttcatgaaat atgtcaccag
     2341 tggtttggtg accttgtgac tccagtttgg tgggaagatg tgtggttgaa ggaaggcttt
     2401 gctcactact ttgaatttgt gggtacagac tacctctacc ctgcctggaa catggagaag
     2461 cagagatttc tgacagatgt tctgcatgaa gtgatgctac ttgatggctt ggccagttcc
     2521 catccagtat cacaggaagt gctacgggca acagatattg acagagtgtt cgactggatc
     2581 gcatacaaaa agggtgctgc tctaattaga atgctggcta attttatggg tcattcagtt
     2641 tttcagaggg gattgcaaga ttatttaacc attcacaagt atggcaatgc agccagaaat
     2701 gatctctgga atacattatc agaggcttta agaaggaatg gaaaatacgt gaacatacaa
     2761 gaagtaatgg atcagtggac actgcagatg ggatatcctg ttatcactat cctgggaaac
     2821 acgacggcag aaaatagaat acttatcacc caacagcatt tcatttatga cattggtgct
     2881 aaaactaaag cacttcaact tcaaaacagc agttacctgt ggcagattcc attaaccatt
     2941 gtggtaggaa atagaagcca tgtgtcttca gaagcaatta tttgggtgtc taacaaatca
     3001 gaacatcaca gaatagcgta cttagacaga ggaagctgga tccttgggaa catcaatcaa
     3061 accggctact ttagagtcaa ctatgaccta aggaactgga gattactaat cgatcagtta
     3121 atcaggaacc acgaggtact ttctgtcagt aaccgcgcgg ctttgatcga tgatgccttc
     3181 agcctggcca gggcaggcta tttgcctcag aatatccccc tagagatcat cagatacctg
     3241 tctgaggaaa aggattttct tccttggcac gctgccagcc gagctcttta tcctctggat
     3301 aaattactgg accgcatgga gaactacaat atcttcaatg aatatattct aaaacaagtt
     3361 gcaacaacat acatcaagct tggatggcca agaaataact tcaatggatc tctcgttcaa
     3421 gcctcctacc aacatgagga gctacggagg gaagtgataa tgttggcatg tagttttggg
     3481 aacaagcact gtcaccagca ggcatcaaca cttatttcag actggatttc cagcaacaga
     3541 aacagaatac ccctgaatgt tagagacatc gtctactgca caggagtgtc actgctggat
     3601 gaggatgtct gggagtttat ctggatgaaa ttccactcta ccactgcagt ttctgagaaa
     3661 aagatactgc tggaggctct aacttgcagc gatgacagga atttattaag taggcttcta
     3721 aatctgtctc tgaattctga ggtggtgttg gatcaagatg caattgatgt aattatccac
     3781 gtagccagaa atccacatgg ccgagacctt gcctggaagt ttttcagaga caaatggaaa
     3841 atactaaata ccaggtatgg agaagcactg tttatgaatt ccaaacttat cagtggagtt
     3901 acagaatttc ttaatacaga aggtgaactt aaagagctaa agaatttcat gaagtcctat
     3961 gatggggtag cctctgcttc tttctcacga gctgtggaaa ctgtggaagc caatgtgcgc
     4021 tggaaaaggt tttaccaaga tgagcttttc cagtggctgg gaaaagccat gagacactaa
     4081 tacccatcac ttatagagca cgcaccctag aactttgtag gaggacctgc tttctgtgga
     4141 atgaggcggc tcgccagaat gtcagtgtta acatgagaga ggatttcctt cttgttttgg
     4201 tgtttgattt gttggggggc tattcttgtt gtttcattga ctctacattt gtgtttttac
     4261 tggatatccc tctataaaga aactcttgca agtgacactt gccctggtta ctccagctgt
     4321 acattcccta ctgttcagga ccaagtatga ttactggtgc atgttaatgt tgctgtcagt
     4381 ttgggaaatc ctattcagac tattctgtgc atggatatat ggtcctgcct gtgttccggc
     4441 atgcttattt aacatgtcca atgttgtatg tgaacattat gtatgtacat ccagaatggg
     4501 cattatgcga aagcacaacg attacctatg acaatcagtg ttgcagtgga agtgaaaaaa
     4561 aatacccact tcagaaggaa attctattct cagccatgga caacgggaga gatacaacag
     4621 ctctctaagc aatctgtgtg gattgtttca gcacttggat tgtctggcaa tgattactga
     4681 gatgttgcta actcactttc tttgagttaa aagctgtgta tacacttgca aagatgtata
     4741 gatagtatgt acatatgcat tatgtacata aggaagatcc atatgtatat agtatgttgt
     4801 acatgcacct gtttgaagac tctcttcaaa tcaaaggaaa cgtagctctt tttttataaa
     4861 tttgtggacc cctggaaaag acttcaagaa gtttatctca acattccaac tttatatatc
     4921 ttgctttctt acatgatttt ttctttttct tttgtctatg tactgaagaa tgatgtatta
     4981 atctaccaca ggaaactgaa ttctaacaaa atacacatgt aaactaacca ctctgcaaag
     5041 tcttttaagt cagtggcaac cttttgccag tttctgtaat tatgtgggtc aacatttcta
     5101 ttgcataaaa caattctgtg taaacttaga atgatcgctg ctaagaaagc gtttctgtag
     5161 agcttcttgg ttttccttag tttcgctact gcagagtgaa attctctctc tgtgttgatc
     5221 tttatgtgta cagtgctcct atccttcatt aagcaaccat acctcaacag gtctattagt
     5281 atttaatgac ctttaatgcc agttgtgccc tcccttaaga cagaaagttg cttttatgct
     5341 gtgttactgt acaaagcctt tgagaattaa caaccctgtt ctacctagga attttgaaga
     5401 gccatttcta tggctgtgtg taacacaact agatttcagt gcttctcgca cccaataggc
     5461 cagctccttg cttcggactc accatatctt aagttgaaca ttgtaaaata tttatacaac
     5521 tattctattg agtcacgcat tgtgtaaccc tttttggttt ttctgtgatg ttcagctctt
     5581 cgaaatgttg ccattaagag actgtcattc aatgctggaa aaaaaatcat ttataaaatg
     5641 gaggtcatag aattattttt gtttgtagaa atgagaagca atttcccaat ccatggacta
     5701 cataaaaact aaatctgaac cttatcatgt aaacaattaa tgtttatttc ttacagctac
     5761 aattttcaac acctcattca atgaaagtac atggattgta attactctgt ggtatgaagg
     5821 agtgatgggc aggtcatgct taacgtgaaa tctgagattt aagttactta ctgaaagtga
     5881 gcaagcttta aagtataacc ttcataatta gtctacagcc acgaggagcc taaataccta
     5941 ttatagcact ggtgaattca ttcataaagc agaactgccc aaagtggtag acatggctgt
     6001 cttgttttgc tcctgacgta ttgtgaatcc tttgagttgg aggcagtgct ttttattttg
     6061 agagagtttt cacttccaac tttgagtttg aggggctttc tcagttctct ttcctcccca
     6121 ttgttaatag tcataatcct ctttcagtgt tttagtggcc ttgaacacaa ctggtttagc
     6181 tattatctaa atcctcagtg cataattatg tgcaatgttt atacctcata caaaacttgt
     6241 tcaacagtct agtggtacca acagcgttga gatggcagtt ttgcgctaca catttttcag
     6301 ttattgaaac tttccgatgt ttaaattata tcaggcttta aagtttctct ttagttgttt
     6361 aaataagtaa tattttcaaa ataataaaaa ctaatgatat ctcttggaat attctgtaaa
     6421 atgtagctat aaaattatat tttctactta gagtttctac ctttctctct tgtgtgtttt
     6481 acagatcaat tatctacatg aaataataat gttttgaaag tgtccacaaa agttcctttc
     6541 ttattgtatg tataacagca aaactttgtt ttaattagaa aatactagat tatttgccac
     6601 tttgggcatt atcatctcta tgtaacttgt aaatataatg ttttcccaat tttca
//
