LOCUS       NM_025960                827 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Mus musculus trafficking protein particle complex 6A (Trappc6a),
            transcript variant 1, mRNA.
ACCESSION   NM_025960
VERSION     NM_025960.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 827)
  AUTHORS   Kim,J.J., Lipatova,Z. and Segev,N.
  TITLE     TRAPP Complexes in Secretion and Autophagy
  JOURNAL   Front Cell Dev Biol 4, 20 (2016)
   PUBMED   27066478
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 827)
  AUTHORS   Chang,J.Y., Lee,M.H., Lin,S.R., Yang,L.Y., Sun,H.S., Sze,C.I.,
            Hong,Q., Lin,Y.S., Chou,Y.T., Hsu,L.J., Jan,M.S., Gong,C.X. and
            Chang,N.S.
  TITLE     Trafficking protein particle complex 6A delta (TRAPPC6ADelta) is an
            extracellular plaque-forming protein in the brain
  JOURNAL   Oncotarget 6 (6), 3578-3589 (2015)
   PUBMED   25650666
REFERENCE   3  (bases 1 to 827)
  AUTHORS   Gwynn,B., Smith,R.S., Rowe,L.B., Taylor,B.A. and Peters,L.L.
  TITLE     A mouse TRAPP-related protein is involved in pigmentation
  JOURNAL   Genomics 88 (2), 196-203 (2006)
   PUBMED   16697553
  REMARK    GeneRIF: The data implicate mammalian TRAPPC6A in vesicle
            trafficking during melanosome biogenesis
REFERENCE   4  (bases 1 to 827)
  AUTHORS   Matthews,R.J., Cahir,E.D. and Thomas,M.L.
  TITLE     Identification of an additional member of the
            protein-tyrosine-phosphatase family: evidence for alternative
            splicing in the tyrosine phosphatase domain
  JOURNAL   Proc Natl Acad Sci U S A 87 (12), 4444-4448 (1990)
   PUBMED   2162042
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC149052.3 and AK007965.1.
            
            On Sep 13, 2016 this sequence version replaced NM_025960.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the shorter isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007965.1, AK008462.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                AC149052.3         137467-137526       c
            61-820              AK007965.1         1-760
            821-827             AC149052.3         130051-130057       c
FEATURES             Location/Qualifiers
     source          1..827
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 9.92 cM"
     gene            1..827
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /note="trafficking protein particle complex 6A"
                     /db_xref="GeneID:67091"
                     /db_xref="MGI:MGI:1914341"
     exon            1..163
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..559
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /note="isoform a is encoded by transcript variant 1;
                     trafficking protein particle complex subunit 6A; TRAPP
                     complex subunit 6A"
                     /codon_start=1
                     /product="trafficking protein particle complex subunit 6A
                     isoform a"
                     /protein_id="NP_080236.2"
                     /db_xref="CCDS:CCDS20905.1"
                     /db_xref="GeneID:67091"
                     /db_xref="MGI:MGI:1914341"
                     /translation="MADAVLFEFLHTEMVAELWAPDPDPGSGGKRRSLSVLEGLGFRV
                     GQALGERLPLETPAFREELDALKFLCRDLWAAMFQKHMDGLRTNHQGTYVLQDNSFPL
                     LVTMGSGPQYLEEAPKFLAFTCGLLCGALHTLGFQSLVTASVASLPACKFQVVIQKS"
     exon            164..231
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /inference="alignment:Splign:2.1.0"
     exon            232..349
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /inference="alignment:Splign:2.1.0"
     exon            350..433
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /inference="alignment:Splign:2.1.0"
     exon            434..527
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /inference="alignment:Splign:2.1.0"
     exon            528..827
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /inference="alignment:Splign:2.1.0"
     regulatory      801..806
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /note="hexamer: AGTAAA"
     polyA_site      823
                     /gene="Trappc6a"
                     /gene_synonym="1810073E21Rik; 4930519D19Rik; mhyp; TRS33"
                     /note="major polyA site"
ORIGIN      
        1 aatcagatcg ggcctacctc ccgagctgac caatgggagc cggaagcgtt ggccaggcgt
       61 gagggtcgcg aggcggcgta tggcggacgc ggtgctattc gagtttctgc acaccgagat
      121 ggtggcggag ctgtgggccc cggacccgga cccaggctcg gggggaaaga ggaggagcct
      181 gtccgtcctg gagggcctgg gcttccgcgt gggccaggct ctgggtgaga ggctgcccct
      241 ggagacaccg gcctttaggg aggagttaga tgccctcaag ttcctgtgca gagatctgtg
      301 ggccgccatg ttccagaagc acatggacgg actccgcacc aaccaccagg ggacctatgt
      361 gctgcaggac aacagcttcc ccctccttgt caccatgggc tcggggccac agtatctaga
      421 ggaagccccc aagttcctgg ccttcacctg cggccttctg tgcggcgccc tccatacact
      481 gggcttccag agcctggtca ccgcctccgt ggcatccctg cccgcctgta agttccaggt
      541 ggtgatccag aagtcctgag gaccccagac cccaggcttg cccttcccta agcttagcct
      601 cggaatgtgg cacctgaccc tgcctcactg ctcacctttg caggtcgcct tgaagctgga
      661 gctcacaggc tctggggagg tcacatgtgc ttcagacaag ggaatgaaag ggccgggagg
      721 gtcccgggag gtgggaccat cccctgagtt ccaagtcagc atggagggac attagggcat
      781 cacccagatg acagatgttc agtaaaggtt ctttatgtgc aaacaga
//
