LOCUS       NM_021789                951 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus trafficking protein particle complex 4 (Trappc4),
            transcript variant 1, mRNA.
ACCESSION   NM_021789
VERSION     NM_021789.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 951)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 951)
  AUTHORS   Hu,M., Bodnar,B., Zhang,Y., Xie,F., Li,F., Li,S., Zhao,J., Zhao,R.,
            Gedupoori,N., Mo,Y., Lin,L., Li,X., Meng,W., Yang,X., Wang,H.,
            Barbe,M.F., Srinivasan,S., Bethea,J.R., Mo,X., Xu,H. and Hu,W.
  TITLE     Defective neurite elongation and branching in Nibp/Trappc9
            deficient zebrafish and mice
  JOURNAL   Int J Biol Sci 19 (10), 3226-3248 (2023)
   PUBMED   37416774
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 951)
  AUTHORS   Wang,X., Weng,M., Ke,Y., Sapp,E., DiFiglia,M. and Li,X.
  TITLE     Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal
            Recycling
  JOURNAL   Cells 9 (5), 1132 (2020)
   PUBMED   32375403
  REMARK    GeneRIF: Kalirin Interacts with TRAPP and Regulates Rab11 and
            Endosomal Recycling.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 951)
  AUTHORS   Kim,J.J., Lipatova,Z. and Segev,N.
  TITLE     TRAPP Complexes in Secretion and Autophagy
  JOURNAL   Front Cell Dev Biol 4, 20 (2016)
   PUBMED   27066478
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 951)
  AUTHORS   Kong,X., Qian,J., Chen,L.S., Wang,Y.C., Wang,J.L., Chen,H.,
            Weng,Y.R., Zhao,S.L., Hong,J., Chen,Y.X., Zou,W., Xu,J. and
            Fang,J.Y.
  TITLE     Synbindin in extracellular signal-regulated protein kinase spatial
            regulation and gastric cancer aggressiveness
  JOURNAL   J Natl Cancer Inst 105 (22), 1738-1749 (2013)
   PUBMED   24104608
  REMARK    GeneRIF: Synbindin contributes to malignant phenotypes of GC by
            activating ERK on the Golgi, and synbindin is a potential biomarker
            and therapeutic target for GC.
REFERENCE   6  (bases 1 to 951)
  AUTHORS   Menon,S., Cai,H., Lu,H., Dong,G., Cai,Y., Reinisch,K. and
            Ferro-Novick,S.
  TITLE     mBET3 is required for the organization of the TRAPP complexes
  JOURNAL   Biochem Biophys Res Commun 350 (3), 669-677 (2006)
   PUBMED   17027922
REFERENCE   7  (bases 1 to 951)
  AUTHORS   Ethell,I.M., Hagihara,K., Miura,Y., Irie,F. and Yamaguchi,Y.
  TITLE     Synbindin, A novel syndecan-2-binding protein in neuronal dendritic
            spines
  JOURNAL   J Cell Biol 151 (1), 53-68 (2000)
   PUBMED   11018053
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122428.4.
            
            On Mar 10, 2023 this sequence version replaced NM_021789.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BI905338.1, BI412763.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-206               AC122428.4         77443-77648
            207-381             AC122428.4         77797-77971
            382-485             AC122428.4         79429-79532
            486-612             AC122428.4         80315-80441
            613-951             AC122428.4         80677-81015
FEATURES             Location/Qualifiers
     source          1..951
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 24.84 cM"
     gene            1..951
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /note="trafficking protein particle complex 4"
                     /db_xref="GeneID:60409"
                     /db_xref="MGI:MGI:1926211"
     exon            1..206
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..691
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /note="isoform 1 is encoded by transcript variant 1;
                     trafficking protein particle complex subunit 4; TRS23
                     homolog; synbindin; syndecan binding protein 2"
                     /codon_start=1
                     /product="trafficking protein particle complex subunit 4
                     isoform 1"
                     /protein_id="NP_068561.1"
                     /db_xref="CCDS:CCDS23109.1"
                     /db_xref="GeneID:60409"
                     /db_xref="MGI:MGI:1926211"
                     /translation="MAIFSVYVVNKAGGLIYQWDSYSPRAEAEKTFSYPLDLLLKLHD
                     ERVLVAFGQRDGIRVGHAVLAINGMDVNGKYTADGKEVLEYLGNPANYPVSIRFGRPR
                     LTSNEKLMLASMFHSLFAIGSQLSPEQGSSGIEMLETDTFKLHCFQTLTGIKFVVLAD
                     PRQAGIDSLLRKIYEIYSDFALKNPFYSLEMPIRCELFDQNLKLALEVAEKAGTFGPG
                     S"
     exon            207..381
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /inference="alignment:Splign:2.1.0"
     exon            382..485
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /inference="alignment:Splign:2.1.0"
     exon            486..612
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /inference="alignment:Splign:2.1.0"
     exon            613..951
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /inference="alignment:Splign:2.1.0"
     regulatory      931..936
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /note="hexamer: AATAAA"
     polyA_site      951
                     /gene="Trappc4"
                     /gene_synonym="1500017G03Rik; HSPC172; PTD009; Sbd; Sbdn;
                     Sdcbp2; TRS23"
                     /note="major polyA site"
ORIGIN      
        1 gggatcgtag taccctatcc gtagcacagt gatggcgatt tttagcgtgt acgtggtgaa
       61 caaagccggc ggcctgattt accagtggga cagctattcg ccacgggctg aggctgagaa
      121 gactttcagt tacccgctgg acctgctgct gaaactgcac gacgaacgcg tgctggtcgc
      181 tttcggccag cgcgacggca tccgggtggg ccatgcagtg ttggccatca atggcatgga
      241 cgtgaatggc aagtacacgg ctgacgggaa agaagtgctg gagtatctgg gtaaccctgc
      301 gaattacccg gtttccatcc gattcggccg gccccgcctt acctctaacg agaagcttat
      361 gctggcctcg atgttccact cgctctttgc cattggttcc cagctatctc cggaacaggg
      421 cagttcaggc attgagatgc tggaaacaga caccttcaaa ctgcactgct tccaaacact
      481 gacagggatc aagtttgtgg tcctggcaga ccctaggcaa gctggaatag attctcttct
      541 ccgaaaaatt tatgaaattt actcagactt tgccctcaag aatccattct actccttgga
      601 aatgcctatc agatgcgagc tgtttgatca aaacctgaag ctagctctag aggtggcaga
      661 gaaggctggc acttttggac ctgggtcata ggatgaacct ggaatggacg ccctaaattc
      721 tgagacgtgc tccagagggc tttgctgtgt ctactcggtg agggtcctgt tgtagcagcc
      781 ttgctaatat acttgaaaat ggtagaccac tgagcctggt gatggtgaca gatcctgggc
      841 tcgaatgctg tgttctctgc ccctctgtat atattacagt cctactctgt atagatttat
      901 ttatggagga aactggctta gcaatgctga aataaacatt cctttgtttt a
//
