LOCUS       NM_001161410            3158 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus trafficking protein particle complex 12 (Trappc12),
            transcript variant 2, mRNA.
ACCESSION   NM_001161410
VERSION     NM_001161410.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3158)
  AUTHORS   Kim,J.J., Lipatova,Z. and Segev,N.
  TITLE     TRAPP Complexes in Secretion and Autophagy
  JOURNAL   Front Cell Dev Biol 4, 20 (2016)
   PUBMED   27066478
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3158)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   3  (bases 1 to 3158)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC136986.6.
            
            On Dec 6, 2019 this sequence version replaced NM_001161410.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR compared
            to variant 1. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK147985.1, AK132166.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AC136986.6         136134-136205       c
            73-1310             AC136986.6         132104-133341       c
            1311-1427           AC136986.6         123538-123654       c
            1428-1541           AC136986.6         108168-108281       c
            1542-1680           AC136986.6         106857-106995       c
            1681-1793           AC136986.6         97677-97789         c
            1794-1866           AC136986.6         89331-89403         c
            1867-1940           AC136986.6         87341-87414         c
            1941-2039           AC136986.6         82949-83047         c
            2040-2140           AC136986.6         78299-78399         c
            2141-2228           AC136986.6         77564-77651         c
            2229-3158           AC136986.6         76433-77362         c
FEATURES             Location/Qualifiers
     source          1..3158
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 11.1 cM"
     gene            1..3158
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /note="trafficking protein particle complex 12"
                     /db_xref="GeneID:217449"
                     /db_xref="MGI:MGI:2445089"
     exon            1..72
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            73..1310
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..2471
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /note="isoform 1 is encoded by transcript variant 2;
                     tetratricopeptide repeat protein 15; TPR repeat protein
                     15; trafficking protein particle complex subunit 12;
                     tetratricopeptide repeat domain 15"
                     /codon_start=1
                     /product="trafficking protein particle complex subunit 12
                     isoform 1"
                     /protein_id="NP_001154882.1"
                     /db_xref="CCDS:CCDS25854.1"
                     /db_xref="GeneID:217449"
                     /db_xref="MGI:MGI:2445089"
                     /translation="METAKDGEQSPSEASPSAQAGPENIPEPMSREEESQPLYHEETI
                     DLGGDEFASEENEPTSEGSHNFGDKLNEHMMESVLISDSPNNSEGDVGDLGCLQDVGE
                     PPRGATDHRLPSSTDKEVVDTLSNGSETDGDDTPRDISDMTPDSRASLKEDSTQEDVT
                     SMPALENAATEEVGPKDSLAPREEQTSEVSSNQSSSKDEPLPVCTIFSQATATPSQPH
                     LFLQDGFESQMVKSPSFSSTSETSAKTPPPMVQPSPSLSTFFGDTMSSNSLASDFFDS
                     FTTSTFISVSNPNAGSPVPEKLSSLTAPVGEKSPDSTSPSYSTRMDRSESGVSRAPLD
                     VPESPKPFSQIQAVFAGSDDPFATALSMSEMDRRNDAWLPSQATREVLMSVATQQYGT
                     VFIDKENLTMPGLKFDNIQGDAVKDLMLRFLGEKAAAKRQVLNASSVEQSFVGLKQLI
                     SCRNWRAAVDLCGRLLTAHGQGYGKNGLPTSHTTDSLQLWFVRLALLVKLGLFQNAEM
                     EFEPFGNLDQPDLYYEYYPHVYPGRRGSMVPFSMRILHAELQQYLGNPQESLDRLHRV
                     KTVCSKILANLEQGLAEDGGLSSVTQESRQASVQLWRSRLGRVLYSMANCLLLMKDYV
                     LAVDAYLTVIKYYPEQEPQLLSGIGRILLQIGDIKTAEKYFQDVEKVTQKLDGLQGKI
                     MVLMNRAFLYLGQNNFAEAHKFFTEILRMDPTNAVANNNAAVCLLYLGKLKDSLRQLE
                     AMVQQDPRHYLHESVLFNLTTMYELESSRSMQKKQSLLEAVASKEGDSFNTQCLKLA"
     exon            1311..1427
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1541
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1542..1680
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..1793
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..1866
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..1940
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1941..2039
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2140
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            2141..2228
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     exon            2229..3158
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2739..2744
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /note="hexamer: AATAAT"
     polyA_site      2774
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /note="major polyA site"
     regulatory      3134..3139
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /note="hexamer: AATAAA"
     polyA_site      3158
                     /gene="Trappc12"
                     /gene_synonym="CGI-87; D930014A20Rik; Ttc15"
                     /note="major polyA site"
ORIGIN      
        1 acttccggtc ttccgtcatc tcttcggacc cttttcgcct gtgggtgacc cgacctcagg
       61 ggcgggtggc agacaacatg gaaacagcta aagatggtga gcagagccca agtgaggcat
      121 ctccttcagc ccaggcaggt cctgaaaaca tcccggagcc tatgtctcgg gaggaggaga
      181 gccagccatt gtaccatgaa gagaccattg atcttggtgg agatgagttt gcatctgaag
      241 agaacgagcc cacatcggaa gggtctcaca acttcggaga taagcttaat gagcacatga
      301 tggaaagtgt gctcatctcc gactctccta acaacagcga gggggacgtt ggcgacctcg
      361 gctgtctaca ggatgttggg gagcccccca gaggtgccac tgatcaccga ctgcccagta
      421 gcacagacaa agaagtggtg gacactctga gtaatggcag tgaaaccgat ggagacgaca
      481 ctcccagaga catctcagac atgacacctg atagcagagc ctctctgaag gaagactcaa
      541 cacaggaaga tgtgacgagc atgcctgcac tggagaatgc tgccacggag gaagtcgggc
      601 ctaaggacag cctcgcgccc cgagaagagc agacctcaga agtgtcctcc aatcagtcct
      661 cctccaaaga cgagcccttg cccgtctgca ccatcttcag ccaggctacc gccactccct
      721 cccagccaca cctgtttcta caggatggct tcgagtccca gatggtgaaa tcacccagtt
      781 tcagtagcac cagtgagacg tcagccaaga cccctcctcc gatggtccag cccagtccca
      841 gcctcagtac attttttgga gatacaatga gctctaattc cttggcctct gacttctttg
      901 attccttcac aacttctact ttcatttcag tcagtaatcc caatgcaggt tccccagttc
      961 cagaaaagct gtcttcactc actgcccctg taggagagaa gtccccggat tccaccagcc
     1021 catcttactc cacaaggatg gatagatcgg aatcaggtgt ttctcgggcc cctctggatg
     1081 tccctgaatc tccaaagcca ttttcacaga tccaggctgt gtttgctgga agtgatgacc
     1141 ccttcgccac agccctgagc atgagtgaga tggaccggag gaatgacgca tggcttccca
     1201 gtcaggcgac cagagaagtc ctgatgtcag tagcaaccca gcagtatggc actgtgttca
     1261 tagacaagga gaacctcact atgcctggcc tcaagtttga caacattcag ggagatgcag
     1321 ttaaagactt gatgcttcgc ttcctgggtg agaaggctgc agcaaagaga caggtcttaa
     1381 atgccagctc agtggagcag tcctttgtgg ggctgaagca gctcattagc tgcaggaact
     1441 ggagggcagc agtcgacctg tgtggacgcc tgctcacagc ccacggacaa ggctatggca
     1501 agaatgggct gcccaccagc cacaccacag actccttgca gctctggttt gtgaggttgg
     1561 cgctgctggt gaagttgggc cttttccaga atgctgagat ggagtttgaa ccctttggaa
     1621 atctggatca accagaccta tactatgaat actacccaca cgtgtaccca ggacgcaggg
     1681 gctccatggt ccccttttcg atgcgtattc tgcatgcaga actgcagcag tatctgggga
     1741 acccacagga gtccctggac cgattacaca gggtcaagac cgtctgcagc aagatcttgg
     1801 ccaacttgga gcaaggctta gctgaagatg gtggtctgag cagcgtcacc caggaaagca
     1861 ggcaagcctc tgttcagctg tggaggtctc gtctgggccg tgtgctgtac tccatggcaa
     1921 actgtctgct cctgatgaag gactatgtgc tggctgtgga tgcctacctc acagtaatca
     1981 agtactaccc ggagcaggag ccacagctgc tgagtggaat cggccgcatt ctcctccaga
     2041 tcggagacat aaaaacagct gaaaaatatt ttcaagacgt tgagaaagta actcagaagt
     2101 tggatggact gcagggtaaa ataatggtcc taatgaacag agcctttctg taccttggcc
     2161 agaataactt cgcagaagct cacaagttct tcacagagat tttgagaatg gacccaacaa
     2221 atgcagtggc caacaacaat gctgctgtgt gtctgcttta cctgggaaag ctcaaggact
     2281 ccctgcggca gctggaggcc atggtgcagc aggaccccag gcactacctg cacgagagcg
     2341 tgctcttcaa cctgaccacc atgtacgagc tggagtcctc aaggagcatg caaaagaagc
     2401 agagcctact tgaggccgtt gctagcaaag aaggggacag cttcaacaca cagtgcctga
     2461 agctggctta gttccctcca ggtctctgta cctgcagaca cttgagcaga tgggtcagta
     2521 aaagcatttg atgggtgtgc aggagcatgc cttcggctgg ctgggctacc ctcagacccg
     2581 ctgacctgcc taccatgcag ttgcacaata ctgcctgttg gtgaaggtga gccatatgca
     2641 tggcattcag aaacagggaa cataaggaca tggggttccc ttggtttgtt catggaagct
     2701 aacttgttct ttggtcactt ctgaatactc gtttggtaaa taatattgcc tgttctcact
     2761 ataggcctaa acaatcacag ttcattgtct tcctccctcc atatcccaaa caaaagtatt
     2821 gctttgatta ttcagctcac tcagaacaca gctgggcaag gagcatcatg ggctggcaca
     2881 gcatctatgc gctcctgtgc ctgaaggcaa gagaattgct taacgcttgt atgcgctttt
     2941 tccactttgc aaaatgtaaa ggacctggaa atggtcttcc gttcccagct ttcctaattc
     3001 atgtgaaaac actcatttta aaggcaggat gcacggctgt gggatgcagc ggagcatcat
     3061 ttgtgcctca cgatctgagg gcatgggttc caccccagct ccataagcaa aactgctggc
     3121 tcttcatgtc tgtaataaag tgaaaagtgt ttgtgtta
//
