LOCUS       NM_001024206             745 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus trafficking protein particle complex 1 (Trappc1),
            mRNA.
ACCESSION   NM_001024206 XM_126252
VERSION     NM_001024206.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 745)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 745)
  AUTHORS   Zhang,Z., Zhao,C., Sun,L., Cheng,C., Tian,Q., Wu,C., Xu,Y.,
            Dong,X., Zhang,B., Zhang,L. and Zhao,Y.
  TITLE     Trappc1 intrinsically prevents ferroptosis of naive T cells to
            avoid spontaneous autoinflammatory disease in mice
  JOURNAL   Eur J Immunol 54 (3), e2350836 (2024)
   PUBMED   38234007
  REMARK    GeneRIF: Trappc1 intrinsically prevents ferroptosis of naive T
            cells to avoid spontaneous autoinflammatory disease in mice.
REFERENCE   3  (bases 1 to 745)
  AUTHORS   Xu,Y., Zhang,Z., Zhao,Y., Zhao,C., Shi,M., Dong,X., Zhang,J.,
            Tan,L., Zhang,L. and Zhao,Y.
  TITLE     TRAPPC1 is essential for the maintenance and differentiation of
            common myeloid progenitors in mice
  JOURNAL   EMBO Rep 24 (2), e55503 (2023)
   PUBMED   36440617
  REMARK    GeneRIF: TRAPPC1 is essential for the maintenance and
            differentiation of common myeloid progenitors in mice.
REFERENCE   4  (bases 1 to 745)
  AUTHORS   Dong,X., Liang,Z., Zhang,J., Zhang,Q., Xu,Y., Zhang,Z., Zhang,L.,
            Zhang,B. and Zhao,Y.
  TITLE     Trappc1 deficiency impairs thymic epithelial cell development by
            breaking endoplasmic reticulum homeostasis
  JOURNAL   Eur J Immunol 52 (11), 1789-1804 (2022)
   PUBMED   35908180
REFERENCE   5  (bases 1 to 745)
  AUTHORS   Kim,J.J., Lipatova,Z. and Segev,N.
  TITLE     TRAPP Complexes in Secretion and Autophagy
  JOURNAL   Front Cell Dev Biol 4, 20 (2016)
   PUBMED   27066478
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 745)
  AUTHORS   Menon,S., Cai,H., Lu,H., Dong,G., Cai,Y., Reinisch,K. and
            Ferro-Novick,S.
  TITLE     mBET3 is required for the organization of the TRAPP complexes
  JOURNAL   Biochem Biophys Res Commun 350 (3), 669-677 (2006)
   PUBMED   17027922
REFERENCE   7  (bases 1 to 745)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   8  (bases 1 to 745)
  AUTHORS   Yamaza,H., Matsuo,K., Kiyoshima,T., Shigemura,N., Kobayashi,I.,
            Wada,H., Akamime,A. and Sakai,H.
  TITLE     Detection of differentially expressed genes in the early
            developmental stage of the mouse mandible
  JOURNAL   Int J Dev Biol 45 (4), 675-680 (2001)
   PUBMED   11461004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK621128.1 and BY479576.1.
            
            [WARNING] On Feb 6, 2025 this sequence was replaced by
            NM_001024206.3.
            
            On Feb 14, 2008 this sequence version replaced NM_001024206.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA468742.1, BI249750.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-650               CK621128.1         1-650
            651-745             BY479576.1         512-606
FEATURES             Location/Qualifiers
     source          1..745
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.51 cM"
     gene            1..745
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /note="trafficking protein particle complex 1"
                     /db_xref="GeneID:245828"
                     /db_xref="MGI:MGI:1098727"
     exon            1..81
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..519
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /note="novel Sybindin-like family domain-containing
                     protein"
                     /codon_start=1
                     /product="trafficking protein particle complex subunit 1"
                     /protein_id="NP_001019377.1"
                     /db_xref="CCDS:CCDS24889.1"
                     /db_xref="GeneID:245828"
                     /db_xref="MGI:MGI:1098727"
                     /translation="MTVHNLYLFDRNGVCLHYSEWHRKKQAGIPKEEEYKLMYGMLFS
                     IRSFVSKMSPLDMKDGFLSFQTSRYKLHYYETPTGIKVVMNTDLGVGPIRDVLHHIYS
                     ALYVEFVVKNPLCPLGQTVQSELFRSRLDSYVRSLPFFSARAG"
     exon            82..180
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /inference="alignment:Splign:2.1.0"
     exon            181..251
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /inference="alignment:Splign:2.1.0"
     exon            252..390
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /inference="alignment:Splign:2.1.0"
     exon            391..745
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      716..721
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /note="hexamer: AATAAA"
     polyA_site      745
                     /gene="Trappc1"
                     /gene_synonym="BET5; D11Ertd172e; MUM2"
                     /note="major polyA site"
ORIGIN      
        1 ggttcttgag gttgccgctt acgacccagc tgggctttat aaaccggaag tagcttgtca
       61 ccctctttca gagcaattcc gatgactgtc cacaatctgt acctttttga ccggaatgga
      121 gtgtgtctac actacagcga gtggcaccgc aagaagcaag cagggatccc taaggaagag
      181 gagtacaagc tgatgtatgg aatgctcttc tccattcgtt cgtttgtcag caagatgtcc
      241 ccgctagaca tgaaggatgg ctttctgtct ttccaaacta gccgttacaa actccattac
      301 tacgagactc ccactggaat caaggttgtc atgaatactg acttgggcgt gggccctatc
      361 cgagatgttc tacaccatat ctacagtgcg ctgtatgtgg agtttgttgt gaagaatcct
      421 ctgtgcccgc tgggacaaac tgtgcaaagt gagctctttc gatcccggct agactcctat
      481 gtccgatctt tgcccttctt ctctgccaga gctggctgaa acatctacct cacccctcag
      541 aagaacctgt gactgcctgg gcccatctca cttgttacat tgagagccct tccatctacc
      601 tgtctccgag agctttcccc cgaaggccta ccacccactg ccttcaagtc ataagaatga
      661 agctcacagg agtctacgcc agttttatcc ctgcttgact ctgtgagaaa cacagaataa
      721 actgaataaa ctttttgtca ccctc
//
