LOCUS       NM_011632               7164 bp    mRNA    linear   ROD 29-OCT-2024
DEFINITION  Mus musculus TNF receptor-associated factor 3 (Traf3), transcript
            variant 1, mRNA.
ACCESSION   NM_011632
VERSION     NM_011632.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 7164)
  AUTHORS   Fan,H., Song,C. and Zhang,J.
  TITLE     Sarm1 Controls the MYD88-Mediated Inflammatory Responses in
            Inflammatory Bowel Disease via the Regulation of TRAF3 Recruitment
  JOURNAL   Immunol Invest 53 (5), 800-812 (2024)
   PUBMED   38651786
  REMARK    GeneRIF: Sarm1 Controls the MYD88-Mediated Inflammatory Responses
            in Inflammatory Bowel Disease via the Regulation of TRAF3
            Recruitment.
REFERENCE   2  (bases 1 to 7164)
  AUTHORS   Tu,L., Cheng,W., Wang,X., Li,Z. and Li,X.
  TITLE     Circular RNA circEfnb2 promotes cell injury after cerebral
            infarction by sponging miR-202-5p and regulating TRAF3 expression
  JOURNAL   Transpl Immunol 84, 102042 (2024)
   PUBMED   38527707
  REMARK    GeneRIF: Circular RNA circEfnb2 promotes cell injury after cerebral
            infarction by sponging miR-202-5p and regulating TRAF3 expression.
REFERENCE   3  (bases 1 to 7164)
  AUTHORS   Zhu,S., Lalani,A.I., Jin,J., Sant'Angelo,D., Covey,L.R., Liu,K.,
            Young,H.A., Ostrand-Rosenberg,S. and Xie,P.
  TITLE     The adaptor protein TRAF3 is an immune checkpoint that inhibits
            myeloid-derived suppressor cell expansion
  JOURNAL   Front Immunol 14, 1167924 (2023)
   PUBMED   37207205
  REMARK    GeneRIF: The adaptor protein TRAF3 is an immune checkpoint that
            inhibits myeloid-derived suppressor cell expansion.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7164)
  AUTHORS   Zorea,J., Motro,Y., Mazor,R.D., Carmi,Y.K., Shulman,Z., Mahajna,J.,
            Moran-Gilad,J. and Elkabets,M.
  TITLE     TRAF3 suppression encourages B cell recruitment and prolongs
            survival of microbiome-intact mice with ovarian cancer
  JOURNAL   J Exp Clin Cancer Res 42 (1), 107 (2023)
   PUBMED   37121997
  REMARK    GeneRIF: TRAF3 suppression encourages B cell recruitment and
            prolongs survival of microbiome-intact mice with ovarian cancer.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7164)
  AUTHORS   Gokhale,S., Victor,E., Tsai,J., Spirollari,E., Matracz,B.,
            Takatsuka,S., Jung,J., Kitamura,D. and Xie,P.
  TITLE     Upregulated Expression of the IL-9 Receptor on TRAF3-Deficient B
            Lymphocytes Confers Ig Isotype Switching Responsiveness to IL-9 in
            the Presence of Antigen Receptor Engagement and IL-4
  JOURNAL   J Immunol 210 (8), 1059-1073 (2023)
   PUBMED   36883978
  REMARK    GeneRIF: Upregulated Expression of the IL-9 Receptor on
            TRAF3-Deficient B Lymphocytes Confers Ig Isotype Switching
            Responsiveness to IL-9 in the Presence of Antigen Receptor
            Engagement and IL-4.
REFERENCE   6  (bases 1 to 7164)
  AUTHORS   Masson,R., Regnier,C.H., Chenard,M.P., Wendling,C., Mattei,M.G.,
            Tomasetto,C. and Rio,M.C.
  TITLE     Tumor necrosis factor receptor associated factor 4 (TRAF4)
            expression pattern during mouse development
  JOURNAL   Mech Dev 71 (1-2), 187-191 (1998)
   PUBMED   9507120
REFERENCE   7  (bases 1 to 7164)
  AUTHORS   Arch,R.H. and Thompson,C.B.
  TITLE     4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve
            growth factor receptor subfamily that bind TNF receptor-associated
            factors and activate nuclear factor kappaB
  JOURNAL   Mol Cell Biol 18 (1), 558-565 (1998)
   PUBMED   9418902
REFERENCE   8  (bases 1 to 7164)
  AUTHORS   Xu,Y., Cheng,G. and Baltimore,D.
  TITLE     Targeted disruption of TRAF3 leads to postnatal lethality and
            defective T-dependent immune responses
  JOURNAL   Immunity 5 (5), 407-415 (1996)
   PUBMED   8934568
REFERENCE   9  (bases 1 to 7164)
  AUTHORS   Wang,X., Bornslaeger,E.A., Haub,O., Tomihara-Newberger,C.,
            Lonberg,N., Dinulos,M.B., Disteche,C.M., Copeland,N., Gilbert,D.J.,
            Jenkins,N.A. and Lacy,E.
  TITLE     A candidate gene for the amnionless gastrulation stage mouse
            mutation encodes a TRAF-related protein
  JOURNAL   Dev Biol 177 (1), 274-290 (1996)
   PUBMED   8660894
REFERENCE   10 (bases 1 to 7164)
  AUTHORS   Cheng,G., Cleary,A.M., Ye,Z.S., Hong,D.I., Lederman,S. and
            Baltimore,D.
  TITLE     Involvement of CRAF1, a relative of TRAF, in CD40 signaling
  JOURNAL   Science 267 (5203), 1494-1498 (1995)
   PUBMED   7533327
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122023.3, CJ127244.1, BC137634.1, AK147362.1 and BF661650.1.
            
            On Oct 30, 2013 this sequence version replaced NM_011632.2.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223971.13082.1,
                                           SRR11927936.197828.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-93                AC122023.3         82820-82912         c
            94-550              CJ127244.1         2-458
            551-4212            BC137634.1         266-3927
            4213-7149           AK147362.1         4028-6964
            7150-7164           BF661650.1         1-15                c
FEATURES             Location/Qualifiers
     source          1..7164
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 60.94 cM"
     gene            1..7164
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /note="TNF receptor-associated factor 3"
                     /db_xref="GeneID:22031"
                     /db_xref="MGI:MGI:108041"
     exon            1..233
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            234..344
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            345..603
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     CDS             362..2065
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /EC_number="2.3.2.27"
                     /note="isoform a is encoded by transcript variant 1; CD40
                     receptor-associated factor 1; RING-type E3 ubiquitin
                     transferase TRAF3; CD40-binding protein"
                     /codon_start=1
                     /product="TNF receptor-associated factor 3 isoform a"
                     /protein_id="NP_035762.2"
                     /db_xref="CCDS:CCDS26175.1"
                     /db_xref="GeneID:22031"
                     /db_xref="MGI:MGI:108041"
                     /translation="MESSKKMDAAGTLQPNPPLKLQPDRGAGSVLVPEQGGYKEKFVK
                     TVEDKYKCEKCRLVLCNPKQTECGHRFCESCMAALLSSSSPKCTACQESIIKDKVFKD
                     NCCKREILALQVYCRNEGRGCAEQLTLGHLLVHLKNECQFEELPCLRADCKEKVLRKD
                     LRDHVEKACKYREATCSHCKSQVPMIKLQKHEDTDCPCVVVSCPHKCSVQTLLRSELS
                     AHLSECVNAPSTCSFKRYGCVFQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLL
                     QNESVEKNKSIQSLHNQICSFEIEIERQKEMLRNNESKILHLQRVIDSQAEKLKELDK
                     EIRPFRQNWEEADSMKSSVESLQNRVTELESVDKSAGQAARNTGLLESQLSRHDQMLS
                     VHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFG
                     YKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVTLMLMDQGSSRRHLG
                     DAFKPDPNSSSFKKPTGEMNIASGCPVFVAQTVLENGTYIKDDTIFIKVIVDTSDLPD
                     P"
     exon            604..655
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            656..760
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            761..928
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1009
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1084
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1177
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            1178..1318
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1493
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..7160
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7136..7141
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /note="hexamer: AATAAA"
     polyA_site      7160
                     /gene="Traf3"
                     /gene_synonym="amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;
                     TRAFAMN"
                     /note="major polyA site"
ORIGIN      
        1 agcgcgcgag aggaagtgcc agcgcgaggg tgcgtgaggc ggcgcggccg gcggccgccg
       61 cgtgcgcgag ccgggttgca gcccagcagg gactttccag ccggcggcgg cggcggcggc
      121 cgccggccct tccccgcccc ccgacatggg gctgcccggg gagctggacg ctgcagaagg
      181 cggcggagga tgcgcgcggc gcccctgagc cggccgaacg ggcgggcctc ggggtacagg
      241 gtccccatta cttgaaggat aaggctggca cggctccgac gtctgtgtgg aagcttctcc
      301 ctcccttctg agcttctcta gactccttac agcgcacggc acagaatttc agtttcctaa
      361 gatggagtca agcaaaaaga tggatgctgc tggcacactg cagcctaacc cacccctaaa
      421 gctgcagcct gatcgcggcg cagggtccgt gctcgtgccg gagcaaggag gctacaagga
      481 gaagtttgtg aagacggtgg aagacaagta caagtgcgag aagtgccgcc tggtgctgtg
      541 caacccgaag cagacggagt gtggccaccg gttctgcgag agctgcatgg ccgccctgct
      601 gagctcctcc agtccaaaat gcacagcgtg ccaagaaagc atcatcaaag acaaggtgtt
      661 taaggataat tgctgcaaga gagagattct ggcccttcag gtctactgtc ggaatgaagg
      721 cagaggttgt gcggagcagc tgactctggg acatctgctg gtgcacctaa aaaatgaatg
      781 tcagtttgag gaacttccct gtctgcgtgc cgactgcaaa gaaaaagtac tgagaaaaga
      841 cttgcgggat cacgtggaaa aggcctgtaa ataccgcgag gccacgtgca gtcactgcaa
      901 gagccaagtg cccatgatca aactgcagaa acatgaagac acagattgtc cctgtgtggt
      961 ggtatcctgc cctcacaagt gcagcgttca gactcttcta aggagtgagt tgagtgcaca
     1021 cttgtccgag tgtgtcaatg cccccagcac ctgtagtttt aagcgctatg gctgcgtttt
     1081 tcagggtaca aaccagcaga tcaaggccca tgaggccagc tccgcggtac agcacgtgaa
     1141 cctgctgaag gagtggagca actccctgga gaagaaggtt tccctgctgc agaatgaaag
     1201 tgttgagaaa aacaagagca tccaaagcct gcacaaccag atctgcagct ttgagatcga
     1261 gattgagagg cagaaggaga tgctccgaaa caacgagtcc aagatccttc acctgcagcg
     1321 ggtaatcgac agccaagcag agaaactgaa agaactggac aaggagatcc gtcccttccg
     1381 gcagaactgg gaggaagcgg acagcatgaa gagcagtgtg gagtccctcc agaaccgagt
     1441 gactgagctg gagagcgtag acaaaagtgc ggggcaggcg gctcgcaaca caggcttgct
     1501 ggagtcccag ctgagccggc atgaccagat gttgagtgtt catgacatcc gcttggccga
     1561 catggacctg cggttccagg tcctcgagac cgccagctac aacggggtgc tgatctggaa
     1621 gatccgtgac tacaagcgcc ggaagcagga ggccgtcatg gggaagaccc tgtctctcta
     1681 cagccagcct ttctacacag gttattttgg ctataagatg tgtgccaggg tctacctgaa
     1741 tggggacgga atggggaaag ggacacactt gtcgctgttt tttgtcatta tgcgtggaga
     1801 atatgatgct ctgttgccat ggccgttcaa gcagaaagtg acacttatgc tgatggatca
     1861 ggggtcctct cgccgtcatc tgggagatgc gttcaagcct gaccccaaca gcagcagctt
     1921 caagaaaccc accggagaga tgaatatcgc ctctggctgc ccagtctttg tcgcccaaac
     1981 tgttctagag aacgggacgt atattaaaga tgatacaatc tttattaagg tcatagtgga
     2041 tacctcggat ctgcctgacc cctgacaaga aagcagggcg gtggattcag cagaaggtaa
     2101 ctcctctggg ggggtgagct agtgtcttca cggaggtcct cgccctcaga aaggaccttg
     2161 tgggacagag gaagcagccg gaggaggaga aggaggtcga gtggctggca ggagagccac
     2221 atgtgaaaac agaccccaac ggattttcta atagactagc cacacccact ctgaaggatt
     2281 atttatccat caacaagata aatactgctg tcagagaagg ttttcatttt cattttaaaa
     2341 gatctagtta attaaggtgg gaacatatat gctaaaaaga aacatgattt ttcttcctta
     2401 acttaaacac caaaaagaga acacatgtgg gggtagctgg atgtgtcagc atgttaacct
     2461 acgaggagaa cttatgaaat cataacacaa tccccatata ctcatcctaa aattcaagag
     2521 tgcaatcttg tttcaaatat agtatattgt ctatttttaa ggcctcatct ggtctctgtt
     2581 ttaataattt gtttgtcaga agaccctgag taggcagaag gtctctaaat tcagaagtca
     2641 tttttaattt aaagttctac aaataattgt tactgcaaac attttgtttt aaaacgttga
     2701 tagactgata tttcttggaa gaaaatgtaa aatatcaaac actggttatc acttgtgata
     2761 ggaaagagaa tattgaacct gctgttattt ctcgttagaa atgtaaccct tcgatatctg
     2821 tcgtagttag tgacactact tcacaatgac tatgagaggg acaatgctca tggatgctgt
     2881 gcatcatttc agacttaaca attgttttca ccctaaaata gggcattagt tgaactttgg
     2941 agttctaaac aaaatcctat aggtttttac aattctgccc catgtttaga caagctctgt
     3001 tgctgacagc accagccttg gtctccagtg tcggtgtccg gggataggca ggtgacccgt
     3061 gccgcaggca ggaggcccca gcgagcatcc catcctgtca tactgctgca tccggctagc
     3121 gcgctccgaa agcaacatcc gtgctcagag atggtggcat acggtacttg tgccttagat
     3181 gtgacatgct gcttcttgtc cctgggtttg cgttcaccat ggttctagaa agtgtcagtt
     3241 taaccagatc tctctccacc accagaactt tgtctctgcc agggccctca ggcaactctg
     3301 aacctgcctg gggatgccag gcctccattg gcagctcttg aagcctctgc tgctaaatat
     3361 tcacagattc caaccgtagg cccctaagag cagctcagtc ccactccaag ggagggaggt
     3421 gtgagcagaa gccacaccct tccaggtctc tgcaagggcc ctgaaatccc cacagcatga
     3481 aggagaagtg ccctagtccc aagcgttccc gagaccactg gtctggggcc tgcccgggct
     3541 ggcagcagca accctggcct ccctgtgagg agggcagcca gctgatgccc agcctgtgag
     3601 tgcagaggcc cgccctctca gctcactgtt cccactgtga tgagaagcct ggagccctgc
     3661 cccggtgccc cttttgctat gcaccacact tcacggtgct ctacactgat gggtgctaca
     3721 cgcgacaggt gcttcttagg caaaaccaat gtgtgcaaac caccacatct gtgccacttg
     3781 cccaaaaggc gcgcccacaa ttggccagct gggcctgcgc ttcagactgc ctgcctctgg
     3841 gctctcccca tggtcgcacg gggacagctg ggttggtgcc cggtagccca ccttgtctct
     3901 ggtgctgcca tctgtcctgg gtgtgccttc gccccagtgc ctgctggaag tgccctcctc
     3961 tcgcacacct gtccccgtgc ttccatgagc gacctcttgg tttcgagcac tcaccctgcc
     4021 cttccatggc tgaagcgttt ggtttgtcct ctgctccccg cttctctcca ttatgctggg
     4081 attgctttgg ggtaagtcag caaccttggt tctgcccaca aggaaagacc gcagagctca
     4141 agttctttca aaggtgccct cctcttcctc taggcctgtc accagggttc ctcccccaaa
     4201 gacctggagt tggggggaac acccagcagt ccttggctgg cttcaggaag cttttctgtg
     4261 gccagatgtc agcaacgggg ccatccctgt agctcccccc ttcagagaaa tcagtgcagt
     4321 atcaacaggt gtaggccagc agcatcgtgt ctgacaaaaa gcatgtctgt ccttagtttc
     4381 agacccttgt atgagggtga ccctgacatg tcctcgggcc cgtcctccct tttagtgaga
     4441 cttggtcaag gctccttcct atgcgaggtg gccctcctgg cttcccccgt gcctgtaggg
     4501 tgtgtgtaaa gtaagtgact gctcccctgg gatgagggcc ctgaacaatg tcacagcttc
     4561 ctgtagtgtg ttgtgtctat tgcatttctc ggtaactgta gaatagtggg caagcttgcc
     4621 cctctgtgcc ctgtctcagt gtgtgaaggg catctcctgg gaggtgtgga gcaggctgcg
     4681 tcctgcctgg gtgtgccttg ctctgctcca tctcagcatt ccttggtgct caccacccgg
     4741 gggtgtgggg cattgttggg ctgtggtctc agcatagctg tggctaccag tcctagcagc
     4801 tagccctcac catatcacag ggtcctggcc atgagaagta tggggtgtca tgcggcgtgt
     4861 gtacctggct gtgcaaaagt gtcaagtgct catcttttaa gaggccggta gttgcatggc
     4921 ctctgtgggg aaattggata caactcctgc ttgccggggt ggtgtttgta cctgctcaca
     4981 gctgaccctg ggaagatggc agccactaac tagcagtgtg tcctgaggcc cagcctgcag
     5041 ttttttgtga atagctgaaa gcttgtgtca gtaacaaccc agggccttcc accttcgttg
     5101 gtcagggaga agaaggtagc ctggggtgcc ctggccgagc ctccttcacc tcttggggat
     5161 agacagagcc agcggaggcc acacatgtag gccgcgtgtg agagggatgg gtgagactgt
     5221 gaatgagtgt aacacactga gtgtgagctg ggctcacaca ggagagcaga gcccatgccc
     5281 agcattccag gaagcaaagg gctgtgagag ggtccgcatc ctcttccttt ctaaagtagc
     5341 ctgtgcacag atggcgccat gtccctaaga cagcacaaca gtcagacagc acagccatga
     5401 gctgagggag gtgtctgctt acagccaccg tccgcctcct ttctttctct gctcttttcc
     5461 cgtttattcc aaggactggg cagcctccag cagggccttc agacccaccc ccaccagatc
     5521 cctttgaaat atgtggtcag cctcatgaga acctagctgt cagccccctg tggatagcta
     5581 gccaccttcc catccctcct tagtcagccc ctgtcccacc aggagttggg acctcatgcc
     5641 tgctatcttg ggcctgacat taactgaaca gtatacatag cagtcaccca cggcagacct
     5701 ggcaaccagt ggacagcatc cagcaaagat gaggatgtct gggcacgcca agtaacgggg
     5761 tcctaggtgg accactcctg ccggcccaag aggagaccag ggggagtgcc agggtcagca
     5821 gcatggccct tgctgcccct ccccctgtgc actgccatgc attgcaggga cttttgtacc
     5881 tggccaaggc atttcccccg acaggtgaca gggttggtca gtcctcactc tcccatacat
     5941 ccctctgctt gggagcatca gtgaatagag aagggcttga tggtgcttag gggactattt
     6001 ttttactttc aatccagaag agctagtgtg ggcttcatgc catcatgtcc tgagtgtgtg
     6061 tgacaaatga gggtctgact ctcgaatctc ctcagaccaa gactctatct tctatttgca
     6121 cacccatagc agctgttttc tccaagctca aatgtgccca cgggggtctg atcaggtgag
     6181 gtgatcattg gcaagtgacc cagccgttgc cagctctccc accccggctg ctgctgctag
     6241 ccacgaggac tgtggcgtcc aggagcccat cccccaacct ggacctatcc tagcctgttg
     6301 tctgcttggg caccattact aggtaggcag gcaaggcagt gacccacacc aaagccagcc
     6361 ctacagctga gcatgcccca gcacccaagc agcgggtatg atccaattcc ctaaccgcac
     6421 cacgtctgga gtctgtcctg tgagctcact gtggaaagga ggttacaagc ccaggtcact
     6481 gtgccactcc atagtcagtg gcgaccagcg tgcaccccta atccccttag tcacttaaga
     6541 aaaccttcaa aggcaaataa atgacctaat tggaaaacac aaaagccggc cttcctccca
     6601 aggattccct aagaatctgt gggcgctctg actgagtagg ttggggtcag tgcagacagc
     6661 tgcagactgt tctaaagttc cgttcttatc tctgatggca cacctctcgt gttcagttct
     6721 attacccaaa aaacaaagac caaagaaggc caatctctca tttgaccgta tttttaatct
     6781 gcctgttttg acacatgccg tctgtagtaa ccgctcgctg tgaggcccca tcttgacagt
     6841 ccaagtgatc gtgaccagtg attagcgtcc cgtgttctaa tgctcttcta agaaactgag
     6901 acagtgtgaa ttattgctca gcaataatca tgtcaccagg agttagcagc acgcctcatc
     6961 tcctgatagc attatgatgt ttcgtgtttt gtttaccgtg tgttacatgt aaggtttcat
     7021 ttggtattta tttgtgtttt gaggtcttgc gatgtttctg ttctgctgct aataataaag
     7081 tttgtaagac tgtagaatgc agaattttgt aatgctcaag tgtctattag aggaaaataa
     7141 agctgattca agagtccggc aaaa
//
